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754521-B21
HPE DL160 Gen9 4LFF CTO Server
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754521-B21 is a high-performance rackmount server engineered for demanding data center, virtualization, file server, and application server environments. It supports Intel Xeon Scalable processors on an LGA 4189 socket with dual-processor (2P) scalability, paired with ECC DDR4 memory offering up to 1 TB capacity across 16 slots. The server features four PCIe 4.0 expansion slots, eight hot-swap NVMe SSD bays in a 2.5-inch drive bay format, and robust RAID 5 support to ensure data integrity on intensive workloads.
754521-B21 also provides redundant power supplies rated at 1200W and active cooling solutions, ensuring continuous performance under heavy loads. Integrated remote management via iDRAC allows for streamlined monitoring and troubleshooting, while the system is optimized for operating systems such as VMware ESXi. This server is ideally suited for enterprise applications in data centers, virtualization, file serving, and advanced application hosting.
754521-B21 price is $749.79, a 19% saving from the Hpe list price of $925.66. 754521-B21 is in stock and available for next-day dispatch. (terms applied)
Request bulk order quote for 754521-B21 for additional pricing. Browse the full Hpe Proliant Dl160 Gen9/10 Servers series or explore all Hpe products.
In small to medium-sized businesses, the HPE DL160 Gen9 4LFF CTO Server (754521-B21) serves as a dense virtualization host using VMware vSphere or Microsoft Hyper-V. Deploying up to eight virtual machines on a single 1U chassis reduces hardware footprint and energy costs. Benefit: Achieve up to 40% lower total cost of ownership and simplified management through consolidated compute resources.
For enterprise applications demanding robust database performance, the HPE DL160 Gen9 4LFF CTO Server (754521-B21) delivers accelerated I/O and high availability. Configured with Intel Xeon processors and four large-form-factor drives, it optimizes Microsoft SQL Server and Oracle databases with sub-millisecond latency. Benefit: Ensure 99.9% uptime and improve transaction processing speeds by up to 30% for mission-critical operations.
Remote and branch offices leverage the HPE DL160 Gen9 4LFF CTO Server (754521-B21) for on-premises file sharing, local backup, and domain services. Its compact 1U profile and four 3.5
To get the detailed certification, please go to the Compliance Center.
| CPU Socket | LGA 4189 | LGA 4677 | LGA 4189 | LGA 4189 | LGA 4189 |
| Cooling | Active | Active | Active | Active | Active |
| Depth | 28 inches | 28.0 | 28 inches | 28 inches | 28.0 inches |
| Drive Bay Size | 2.5-inch | 3.5-inch | Mixed | 3.5-inch | 3.5-inch |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | Yes | Yes | Yes | Yes | Yes |
| Height | 3.5 inches | 3.5 | 3.5 inches | 3.44 inches | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 4 | 4 | 4 | 2 | 4 |
| Max Cores per CPU | 32 | 32 | 32 | 32 | 32 |
| Max RAM Capacity | 1 TB | 2 TB | 1 TB | 1 TB | 512 GB |
| Max Threads per CPU | 64 | 64 | 64 | 64 | 64 |
| Network Interface | 10GbE | 10GbE | 10GbE | 10GbE | 10GbE |
| Operating System | VMware ESXi | VMware ESXi | VMware ESXi | VMware ESXi | Windows Server / VMware ESXi / Ubuntu / RHEL / SUSE / CentOS |
| PCIe Slots | 4 | 4 | 4 | 4 | 6 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 1200W | 1200W | 1000W | 1200W | 750W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 4th Gen | Xeon 4th Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | 754521-B21 High Performance Rack Server | 830577-S01 Advanced Enterprise Server | 878968-B21 Server | 754522-B21 High Performance Rackmount Server | 754520-B21 |
| Product Type | Server | Server | Server | Server | Server |
| RAID Support | RAID 5 | RAID 10 | RAID 10 | RAID 10 | RAID 5 |
| RAM Slots | 16 | 16 | 16 | 16 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| Rail Kit Included | Yes | Yes | Yes | Yes | Yes |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 8 | 8 | 8 | 8 |
| Storage Type | NVMe SSD | SATA SSD | Hybrid | SATA HDD | SATA SSD |
| Use Case | Virtualization | Virtualization | Virtualization / File Server / Application Server | Virtualization | Virtualization / File Server / Application Server |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 50 lbs | 45 | 50 lbs | 45 lbs | 50 lbs |
| Width | 17.5 inches | 17.5 | 17.5 inches | 19 inches | 17.0 inches |
4LFF CTO server fit our storage needs.
Stable and quiet operation.
Consistent performance.
Good value for enterprise use.
Reliable ProLiant server.
The HPE DL160 Gen9 4LFF CTO Server features dual Intel Xeon E5-2600 v3/v4 processors, up to 512 GB DDR4 ECC memory across eight DIMM slots, four LFF hot-plug drive bays, and flexible PCIe expansion for versatile data center workloads.
It supports Intel Xeon E5-2600 v3 and v4 product families, offering up to 22 cores per processor and Turbo Boost for optimized multi-threaded performance.
The server supports up to 512 GB of DDR4 ECC RDIMM or LRDIMM memory at speeds up to 2400 MT/s across eight DIMM slots for high reliability and performance.
It includes four large form factor (3.5") hot-plug drive bays supporting SAS, SATA, and nearline SAS drives up to 10 TB each, plus optional onboard M.2 or NVMe boot modules.
Compatible RAID options include HPE Smart Array P440ar, P440, P840, and B140i controllers providing hardware RAID levels 0, 1, 5, 6, 10, and 50 for data protection.
Standard networking includes FlexibleLOM for up to 10 GbE ports, with optional 1/10/25/40/100 Gb Ethernet and InfiniBand adapters via PCIe slots.
The server supports single or redundant hot-plug HPE Flexible Slot Power Supplies configurable between 500 W and 800 W for efficiency and high availability.
Yes, it is certified for VMware vSphere, Microsoft Hyper-V, Red Hat, and Citrix XenServer, delivering optimized virtual machine density and performance.
It includes HPE iLO 4 for secure remote management and supports HPE OneView and Insight Control for unified infrastructure automation.
Yes, the DL160 Gen9 is fully compatible with HPE OneView for software-defined infrastructure automation and lifecycle management.
Ideal for SMB databases, web hosting, virtualization, and high-performance computing workloads requiring scalable compute and storage.
It uses redundant hot-swappable fans, advanced thermal sensors, and iLO-driven fan speed optimization to maintain efficient cooling under load.
Standard HPE 3-year parts, labor, and onsite support is included, with optional HPE Foundation Care and Proactive Care upgrades for extended coverage.
It offers scalable compute, memory, storage, and networking options with support for dual processors, up to eight DIMMs, multiple drive bays, and PCIe expansion slots.
Certified OS options include Windows Server 2012/2016/2019, Red Hat Enterprise Linux, SUSE Linux Enterprise Server, VMware ESXi, and Ubuntu LTS releases.
Yes, remote deployment is supported via HPE iLO 4 virtual media, scripting tools, and the HPE Scripting Toolkit for automated headless installations.
It provides up to three PCIe Gen3 slots, a FlexibleLOM bay, and optional mezzanine cards for Ethernet, InfiniBand, or converged fabrics.