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P06453-B21
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- HPE ProLiant DL360 Gen10 4110 2.1GHz 8-core 1P 16GB-R P408i-a 8SFF 500W PS Performance Server
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Return any product within 14 days of delivery if it doesn’t meet your technical or operational needs.
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All equipment includes a 30-day replacement warranty. If something goes wrong, we’ll repair or swap it — fast.
Replacements shipped in 10 days or less.
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P06453-B21 Overview
P06453-B21 is a high-performance rackmount server that supports Intel Xeon Scalable processors with an LGA 4189 socket. It is designed for 2P scalability, runs on ECC DDR4 memory technology with up to 512 GB capacity, and offers ample expansion opportunities with four PCIe slots. Additionally, it provides robust storage options with 12 available bays designed for 3.5-inch drives and supports RAID configurations including RAID 0, 1, 5, and 10.
P06453-B21 also features integrated networking with dual 1GbE LAN ports, redundant power supplies rated at 750W, and active cooling to ensure optimal performance under demanding workloads. The server includes remote management via IPMI, supports multiple operating systems such as Windows Server, VMware ESXi, and Ubuntu, and is ideally suited for data center deployments, virtualization environments, file serving, and application hosting.
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P06453-B21 Specifications
| Product Type | Server |
| Form Factor | Rackmount |
| Rack Units | 2U |
| Processor Brand | Intel |
| Processor Series | Intel Xeon Scalable |
| Processor Generation | Xeon 3rd Gen |
| Use Case | Virtualization / File Server / Application Server |
| CPU Socket | LGA 4189 |
| Scalability | 2P |
| Max Cores Per CPU | 32 |
| Max Threads Per CPU | 64 |
| RAM Type | ECC DDR4 |
| RAM Slots | 8 |
| Max RAM Capacity | 512 GB |
| Storage Type | SATA HDD |
| Storage Bays | 12 |
| Drive Bay Size | 3.5-inch |
| Hot-Swap Support | Yes |
| RAID Support | RAID 0 / RAID 1 / RAID 5 / RAID 10 |
| PCIe Slots | 4 |
| PCIe Version | PCIe 4.0 |
| Network Interface | 1GbE |
| LAN Ports | 2 |
| Remote Management | IPMI |
| Power Supply | Redundant |
| Power Supply Wattage | 750W |
| Cooling | Active |
| Operating System | Windows Server |
| Virtualization Ready | Yes |
| GPU Support | No |
| Rail Kit Included | No |
| Product Name | P06453-B21 High Performance Rackmount Server |
| Height | 3.5 inches |
| Width | 19 inches |
| Depth | 28 inches |
| Weight | 45 lbs |
P06453-B21 Use Case
Virtualization and Workload Consolidation for SMB Efficiency
In a 200-user mid-sized enterprise, IT architects deploy the P06453-B21 HPE ProLiant DL360 Gen10 4110 2.1GHz 8-core 1P 16GB-R P408i-a 8SFF 500W PS Performance Server to consolidate 50+ Linux and Windows virtual machines. Leveraging HPE iLO 5 remote management and the Smart Array P408i-a RAID controller, they achieve a 60% reduction in rack density, 40% lower power usage, and 30% faster VM provisioning. Outcome: maximized hardware utilization, simplified operations, and scalable growth at reduced TCO.
High-Performance OLTP Database Acceleration in Retail
A nationwide retail chain implements a cluster of P06453-B21 HPE ProLiant DL360 Gen10 4110 2.1GHz 8-core 1P 16GB-R P408i-a 8SFF 500W PS Performance Servers to host their Oracle and PostgreSQL transaction engines. With NVMe-backed 8SFF storage, HPE Smart Array P408i-a RAID, and 16 GB RDIMM memory per node, the setup sustains 10,000+ transactions per second at sub-millisecond latency. Outcome: uninterrupted point-of-sale performance, enterprise-grade data integrity, and full PCI DSS compliance.
Edge AI/ML Inference for Predictive Maintenance in Manufacturing
In an automotive assembly plant, operations teams install the P06453-B21 HPE ProLiant DL360 Gen10 4110 2.1GHz 8-core 1P 16GB-R P408i-a 8SFF 500W PS Performance Server at line-side workcells to run TensorFlow and ONNX inference on streaming sensor data. The 8-core CPU and low-latency local SSD array process 1 TB of telemetry daily, predicting equipment anomalies with 95% accuracy in real time. Outcome: 25% reduction in unplanned downtime, lower maintenance costs, and optimized production throughput.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table
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| Cooling | Active | Active | Active | Active | Active |
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Depth | 30 | 28 inches | 28 inches | 28 inches | 30 inches |
| Drive Bay Size | 3.5-inch | 2.5-inch | 2.5-inch | 3.5-inch | Mixed |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | No | No | Yes | No | Yes |
| Height | 1.75 | 3.44 inches | 3.5 inches | 3.5 inches | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 2 | 2 | 4 | 2 | 2 |
| Max Cores per CPU | 32 | 32 | 32 | 32 | 32 |
| Max RAM Capacity | 2 TB | 1 TB | 1 TB | 512 GB | 1 TB |
| Max Threads per CPU | 64 | 64 | 64 | 64 | 64 |
| Network Interface | 10GbE | 10GbE | 10GbE | 1GbE | 10GbE |
| Operating System | VMware ESXi | Windows Server | VMware ESXi | Windows Server | VMware ESXi |
| PCIe Slots | 4 | 4 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 750W | 800W | 1200W | 750W | 1000W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 4th Gen | Xeon 3rd Gen | Xeon 4th Gen | Xeon 3rd Gen | Xeon 4th Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | 867959-B21 Enterprise Rackmount Server | P03632-B21 Enterprise Server | Enterprise Server 818208-B21 | P06453-B21 High Performance Rackmount Server | SuperServer 874460-S01 |
| Product Type | Server | Server | Server | Server | Server |
| Rack Units | 1U | 2U | 2U | 2U | 2U |
| RAID Support | RAID 10 | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 5 | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 0 / RAID 1 / RAID 5 / RAID 10 |
| Rail Kit Included | N/A | Yes | Yes | No | Yes |
| RAM Slots | 16 | 16 | 16 | 8 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Remote Management | iDRAC | iDRAC | iDRAC | IPMI | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 8 | 8 | 12 | 8 |
| Storage Type | SATA SSD | SATA SSD | SATA SSD | SATA HDD | SATA SSD |
| Use Case | Data Center / Virtualization / File Server / Application Server | Virtualization | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server | Virtualization |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 50 | 45 lbs | 50 lbs | 45 lbs | 60 lbs |
| Width | 19 | 19 inches | 17.2 inches | 19 inches | 19 inches |
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Questions & Answers
Q
What are the key features of the HPE ProLiant DL360 Gen10 4110 server?
A
The HPE ProLiant DL360 Gen10 4110 delivers a 2.1 GHz 8-core Intel® Xeon® 4110 CPU, 16 GB DDR4 memory, HPE Smart Array P408i-a RAID controller, eight 2.5″ SFF drive bays, a 500 W Platinum power supply and HPE iLO 5 management—all in a 1U rack form factor.
Q
Which processor does the DL360 Gen10 4110 include and what performance can I expect?
A
It includes a single Intel® Xeon® Silver 4110 processor (2.1 GHz base, up to 3.0 GHz Turbo, 8 cores, 11 MB cache) designed for secure performance, virtualization and moderate workload consolidation.
Q
How much memory does this server support and what is preinstalled?
A
The server supports up to 1 TB of DDR4 Registered DIMMs across 24 DIMM slots. It ships with 16 GB (1 x 16 GB) DDR4-2666 MT/s RDIMM, providing room for future expansion.
Q
What storage options are available on the DL360 Gen10 4110?
A
This model offers eight front-accessible 2.5″ SFF drive bays, compatible with SAS/SATA HDDs or SSDs and NVMe drives, plus optional M.2 and flexible LOM storage modules for caching or boot devices.
Q
What RAID levels does the HPE Smart Array P408i-a support?
A
The embedded HPE Smart Array P408i-a supports RAID 0, 1, 5, 6, 10, 50 and 60 with up to 12 GB/s internal bandwidth and 2 GB cache (Upgradeable to 4 GB), ensuring data protection and performance.
Q
Can I expand PCIe slots in this server?
A
Yes. The DL360 Gen10 4110 includes three PCIe 3.0 slots (one x16, two x8) for additional network adapters, storage controllers or accelerator cards to scale I/O performance.
Q
What networking connectivity is onboard?
A
It features FlexibleLOM with two integrated 10 GbE ports. You can upgrade to FlexibleLOM 25/50/100 GbE or use PCIe NICs for enhanced bandwidth and redundancy.
Q
How efficient is the power supply?
A
The server includes a 500 W HPE Flex Slot Platinum power supply with up to 94% efficiency. Optional redundant PSUs and power capping features optimize energy usage and uptime.
Q
What remote management capabilities does iLO 5 provide?
A
HPE iLO 5 offers secure remote console, firmware updates, power control, health monitoring, Active System ROM updates and Automated Recovery, simplifying administration and reducing downtime.
Q
Is the DL360 Gen10 4110 suitable for virtualization?
A
Yes. With Intel® VT-x/vt-d, up to 1 TB memory, multiple cores and high bandwidth storage, this server supports VMware, Hyper-V, KVM and other hypervisors for efficient VM consolidation.
Q
Which operating systems are compatible with this server?
A
It supports a wide range of OS including Microsoft Windows Server, various Linux distributions (RHEL, SUSE, CentOS, Ubuntu), VMware ESXi and HPE-certified virtualization environments.
Q
What security features are built into the DL360 Gen10?
A
Security features include Silicon Root of Trust, Secure Boot, TPM 2.0, Runtime Firmware Validation, encrypted recovery, HPE Secure Erase and Secure Start to protect against firmware attacks.
Q
What are common use cases for the HPE ProLiant DL360 Gen10 4110?
A
Ideal for enterprise virtualization, database workloads, web hosting, remote office/branch office (ROBO) deployments and high-performance computing in a space-constrained data center.
Q
How does the DL360 Gen10 ensure high availability?
A
The server offers hot-plug drives, redundant power options, redundant fans, HPE Smart Array RAID, HPE iLO Advanced health monitoring and proactive firmware management for maximum uptime.
Q
What are the physical dimensions and rack requirements?
A
This is a 1U rack server measuring 1.7″ x 17.0″ x 26.0″ (4.3 cm x 43.2 cm x 66.0 cm) and fits standard 19″ racks with a minimum 600 mm depth and proper airflow.
Q
What warranty and support options are available?
A
HPE offers a 3-year parts, labor and onsite limited warranty. Optional Care Pack services include 24×7 support, next-business-day response, Proactive Care and Foundation Care for extended coverage.