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754537-B21
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- HPE ML350T09 LFF CTO Server
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754537-B21 Overview
754537-B21 is a robust rackmount server engineered for high-performance data centers, featuring Intel Xeon Scalable processors on an LGA 4189 socket with a 2P scalability option. Designed for demanding workloads, it supports ECC DDR4 memory up to 512 GB distributed across 16 slots, and includes multiple PCIe 4.0 expansion slots for additional connectivity required in virtualization and application server environments.
754537-B21 also offers 8 hot-swappable 3.5-inch storage bays compatible with a hybrid storage environment that supports both SATA HDD and NVMe SSD configurations along with RAID 10 protection. With integrated 10GbE network interfaces across 4 LAN ports, a redundant 800W power supply, active cooling, and remote management via iDRAC, this server is optimized to run operating systems such as Windows Server, VMware ESXi, and RHEL, making it ideal for data centers, virtualization, file servers, and application servers.
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754537-B21 Specifications
| Product Type | Server |
| Form Factor | Rackmount |
| Rack Units | 2U |
| Processor Brand | Intel |
| Processor Series | Intel Xeon Scalable |
| Processor Generation | Xeon 3rd Gen |
| Use Case | Virtualization |
| CPU Socket | LGA 4189 |
| Scalability | 2P |
| Max Cores Per CPU | 32 |
| Max Threads Per CPU | 64 |
| RAM Type | ECC DDR4 |
| RAM Slots | 16 |
| Max RAM Capacity | 512 GB |
| Storage Type | Hybrid |
| Storage Bays | 8 |
| Drive Bay Size | 3.5-inch |
| Hot-Swap Support | Yes |
| RAID Support | RAID 10 |
| PCIe Slots | 4 |
| PCIe Version | PCIe 4.0 |
| Network Interface | 10GbE |
| LAN Ports | 4 |
| Remote Management | iDRAC |
| Power Supply | Redundant |
| Power Supply Wattage | 800W |
| Cooling | Active |
| Operating System | Windows Server |
| Virtualization Ready | Yes |
| GPU Support | No |
| Rail Kit Included | N/A |
| Product Name | 754537-B21 |
| Height | 3.5 inches |
| Width | 17.5 inches |
| Depth | 28 inches |
| Weight | 75 lbs |
754537-B21 Use Case
Virtual Infrastructure Consolidation with HPE ML350T09 LFF CTO Server
A mid-size enterprise leverages the HPE 754537-B21 ML350T09 LFF CTO Server to virtualize 50+ Windows and Linux workloads under VMware vSphere. By deploying dual Intel® Xeon® Scalable processors, 512 GB DDR4 memory, and HPE Smart Array RAID, the organization achieves 40% reduction in physical servers, simplifies management via HPE iLO, and cuts energy costs by 30%. The outcome: improved resource utilization, business agility, and sub-1-hour provisioning for new virtual machines.
High-Performance Database Hosting for Mission-Critical Apps
A global retail chain uses the HPE ML350T09 LFF CTO Server as the backbone for its Microsoft SQL Server and Oracle databases. Configured with NVMe caching, 24 LFF drive bays, and HPE Persistent Memory, the solution delivers sub-5 ms query response times and 99.99% availability. Integrated HPE OneView ensures automated firmware updates and rapid scale-out, enabling real-time inventory management and seamless peak-season performance.
On-Premises Backup & Disaster Recovery for Regulated Environments
A regional healthcare provider deploys the 754537-B21 HPE ML350T09 LFF CTO Server as a dedicated backup target using Veeam and HPE StoreEasy. With eight LFF drives in RAID 6, redundant power supplies, and HPE iLO remote management, the team enforces sub-15 minute RPO and one-hour RTO for patient records. The result: full compliance with HIPAA retention rules, rapid failover testing, and zero unplanned downtime over 12 months.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table
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| Cooling | Active | Active | Active | Active | Active |
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Depth | 28 inches | 28 inches | 28 inches | 28 inches | 28 inches |
| Drive Bay Size | 3.5-inch | 2.5-inch | 3.5-inch | Mixed | 3.5-inch |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | Yes | Yes | Yes | Yes | No |
| Height | 3.5 inches | 3.5 inches | 3.5 inches | 3.5 inches | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 2 | 2 | 2 | 4 | 4 |
| Max Cores per CPU | 32 | 32 | 32 | 32 | 32 |
| Max RAM Capacity | 512 GB | 1 TB | 1 TB | 1 TB | 512 GB |
| Max Threads per CPU | 64 | 64 | 64 | 64 | 64 |
| Network Interface | 10GbE | 10GbE | 10GbE | 10GbE | 10GbE |
| Operating System | Windows Server | VMware ESXi | Windows Server | Ubuntu | Windows Server |
| PCIe Slots | 5 | 4 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 750W | 1000W | 750W | 1000W | 800W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | 877620-001 | P11051-AA1 High Performance Rack Server | 765821-001 Enterprise Rackmount Server | 835263-001 Enterprise Rackmount Server | 754537-B21 |
| Product Type | Server | Server | Server | Server | Server |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| RAID Support | RAID 5 | RAID 0 / RAID 1 / RAID 5 / RAID 6 / RAID 10 | - | RAID 10 | RAID 10 |
| Rail Kit Included | N/A | Yes | N/A | Yes | N/A |
| RAM Slots | 16 | 16 | 16 | 12 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 1P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 8 | 4 | 8 | 8 |
| Storage Type | SATA HDD | SATA SSD | SATA HDD | Hybrid | Hybrid |
| Use Case | Virtualization | Virtualization | Virtualization / File Server / Application Server | Virtualization | Virtualization |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 45 lbs | 45 lbs | 65 lbs | 50 lbs | 75 lbs |
| Width | 17.5 inches | 17 inches | 17 inches | 17 inches | 17.5 inches |
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Questions & Answers
Q
What are the key features of the HPE ML350T09 LFF CTO Server?
A
The HPE ML350T09 LFF CTO Server features dual Intel Xeon Scalable processors, up to 768 GB DDR4 memory, eight hot-plug 3.5-inch drive bays, redundant power supplies, integrated HPE iLO 5 management, and flexible PCIe expansion.
Q
Which processors does the HPE ML350T09 support?
A
It supports up to two Intel Xeon Scalable CPUs with up to 28 cores each, delivering high performance for compute-intensive and virtualization workloads.
Q
What is the maximum memory capacity of the ML350T09 server?
A
The server supports up to 12 DDR4 ECC DIMM slots, allowing a maximum of 768 GB memory for large data sets and multitasking.
Q
How many hard drives can the LFF CTO server accommodate?
A
The HPE ML350T09 includes eight Large Form Factor (3.5-inch) hot-plug drive bays, supporting up to 96 TB of internal storage with 12 TB drives.
Q
Which storage and RAID controller options are available?
A
You can choose HPE Smart Array controllers such as the P408i-a with RAID 0/1/5/6/10/50 support and optional cache for enhanced performance and data protection.
Q
How many PCIe expansion slots does it offer?
A
The system provides up to seven PCIe Gen3 slots, including full-height and half-height options for networking, graphics, and specialized cards.
Q
What networking ports are integrated?
A
Built-in dual 1 GbE ports are standard, with optional FlexibleLOM or PCIe adapters supporting 10/25/40/100 GbE for scalable connectivity.
Q
Which management tools and interfaces are included?
A
The server features HPE Integrated Lights-Out (iLO 5) for secure remote management, HPE OneView integration, and mobile access via the iLO Mobile app.
Q
What power supplies and redundancy features are supported?
A
It supports redundant hot-plug Flex Slot power supplies up to 1600 W with Platinum efficiency, ensuring continuous operation under heavy loads.
Q
Which operating systems are compatible?
A
The ML350T09 is certified for Windows Server, Red Hat Enterprise Linux, SUSE Linux Enterprise Server, VMware ESXi, and other major enterprise OSs.
Q
Is the server certified for virtualization platforms?
A
Yes, it is certified for VMware vSphere, Microsoft Hyper-V, and Red Hat Virtualization to optimize performance in virtual environments.
Q
What security features are built in?
A
Integrated security includes Secure Boot, Silicon Root of Trust, TPM 2.0, chassis intrusion detection, and optional Smart Card or USB key access.
Q
What warranty and support options are available?
A
HPE offers a standard 3-year Parts, Labor, and Onsite warranty with 24×7 coverage, plus optional Proactive Care and Datacenter Care services.
Q
What is the typical power consumption?
A
Typical power usage is around 250 W at idle and up to 600 W under full load, depending on configuration and workload.
Q
Can the HPE ML350T09 be customized further?
A
As a CTO model, it allows configuration of processors, memory, storage, network adapters, and power supplies to meet specific business requirements.
Q
What form factor and rack mounting options are available?
A
The server ships as a tower (17.5×7.7×17 inches) and can be converted to a 5U rack-mount unit using an optional conversion kit.
Q
Who is the ideal user for this server?
A
The ML350T09 is ideal for small to medium businesses seeking scalable compute performance, high availability, and remote management in tower or rack environments.