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877626-B21
HPE ML350 Gen10 SFF CTO Server
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877626-B21 is a rackmount server that supports Intel Xeon Scalable processors with an LGA 4189 socket and offers 2P CPU scalability. It accommodates ECC DDR4 memory up to 1 TB across 16 DIMM slots, provides 4 PCIe expansion slots, and features 8 hot-swap 2.5-inch storage bays with RAID 0, RAID 1, RAID 5, and RAID 10 support.
This product is equipped with dual redundant 800W power supplies, active cooling, and remote management via iDRAC. It integrates 4 x 1GbE network interfaces, supports operating systems such as Windows Server, VMware ESXi, and RHEL, and is ideally suited for data center virtualization, file serving, and application hosting use cases.
877626-B21 price is is available on request. Get immediate quote.
Request bulk order quote for 877626-B21 for additional pricing. Browse the full Hpe Proliant Ml350 Gen9/10 Servers series or explore all Hpe products.
In a mid-sized financial services firm, IT teams deploy the 877626-B21 HPE ML350 Gen10 SFF CTO Server as a VMware ESXi host to consolidate 20+ critical Windows and Linux VMs onto a single chassis. This reduces rack-space footprint by 60%, cuts power costs by 30%, and delivers sub-millisecond response times for front-office trading applications, driving a 2× improvement in overall infrastructure ROI.
A healthcare analytics provider implements the HPE ML350 Gen10 SFF CTO Server (877626-B21) to run mixed OLTP/OLAP workloads on Microsoft SQL Server and MongoDB, leveraging 8 NVMe drives and dual Intel Xeon Scalable CPUs. The result is sustained 150,000 IOPS, sub-millisecond query latency, and 99.99% uptime—empowering timely patient data insights while meeting stringent HIPAA and uptime SLAs.
A global retail chain deploys the HPE ML350 Gen10 SFF CTO Server (877626-B21) at 50+ branch locations to host local POS, backup, and edge analytics workloads, integrated with HPE GreenLake hybrid cloud. This edge-to-cloud design slashes WAN traffic by 40%, accelerates inventory restocking insights, and centralizes IT management—achieving a 25% reduction in total cost of ownership and faster branch-level decision making.
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| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4677 | LGA 4189 |
| Cooling | Active | Active | Active | Active | Active |
| Depth | 28.0 inches | 28 inches | 28 inches | 28 inches | 28 inches |
| Drive Bay Size | 2.5-inch | 3.5-inch | 3.5-inch | Mixed | 3.5-inch |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | No | No | Yes | No | Yes |
| Height | 3.5 inches | 3.5 inches | 3.44 inches | 3.5 inches | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 4 | 2 | 4 | 4 | 4 |
| Max Cores per CPU | 32 | 32 | 32 | 16 | 16 |
| Max RAM Capacity | 1 TB | 512 GB | 512 GB | 512 GB | 1 TB |
| Max Threads per CPU | 64 | 64 | 64 | 32 | 32 |
| Network Interface | 1GbE | 10GbE | 10GbE | 10GbE | 10GbE |
| Operating System | Windows Server | VMware ESXi | Windows Server / VMware ESXi | VMware ESXi | VMware ESXi |
| PCIe Slots | 4 | 4 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 800W | 750W | 800W | 800W | 750W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | 877626-B21 | 765822-001 High Performance Rack Server | P11053-001 Enterprise Server | 835851-S01 Enterprise Rack Server | 877619-001 |
| Product Type | Server | Server | Server | Server | Server |
| RAID Support | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 5 | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 10 | RAID 5 |
| RAM Slots | 16 | 16 | 16 | 8 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| Rail Kit Included | Yes | N/A | Yes | Yes | Yes |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 8 | 12 | 8 | 8 |
| Storage Type | SATA SSD | SATA SSD | Hybrid | Hybrid | SATA HDD |
| Use Case | Virtualization | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 45 lbs | 75 lbs | 55 lbs | 45 lbs | 50 lbs |
| Width | 17.3 inches | 19 inches | 19 inches | 19 inches | 17 inches |
Gen10 SFF CTO server fits well in space constrained environments.
Reliable and easy to configure.
Consistent performance with custom setups.
Good airflow and thermal management.
Meets enterprise expectations for reliability.
The HPE ML350 Gen10 SFF CTO Server features dual Intel Xeon Scalable processors, up to 3 TB DDR4 memory, eight SFF drive bays, HPE iLO 5 management, and modular expandability.
The HPE ML350 Gen10 SFF CTO supports up to 3 TB of DDR4 ECC memory across 24 DIMM slots for high-performance workloads.
This server is compatible with Intel Xeon Scalable Gold and Platinum processors, up to 28 cores per CPU for intensive compute tasks.
The ML350 Gen10 SFF CTO offers eight 2.5″ hot-plug drive bays supporting SAS, SATA, or NVMe SSDs for flexible high-performance storage.