United States$5,000,000+
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Matthew King
4
Good midline drive for bulk storage. Reliable and cost-effective.
765466-B21
HPE 2TB SAS 12G Midline 7.2K SFF (2.5in) SC 1yr Wty 512e HDD
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765466-B21
- Description:
- HPE 2TB SAS 12G Midline 7.2K SFF (2.5in) SC 1yr Wty 512e HDD
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- List Price:
$1,257.00
- Price:
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765466-B21 Overview
765466-B21 is a high-performance HDD engineered to meet the demands of modern data centers and enterprise storage environments. It features a 3.5-inch form factor, SATA III interface, and a 7200 RPM spindle speed, delivering a robust 4 TB capacity with a 256 MB cache and an annual workload rating of 550 TB/yr.
765466-B21 is enhanced with advanced features such as a helium-sealed design and dual actuator technology that provide superior vibration protection and efficient thermal management. Optimized for continuous operation in desktops, servers, NAS, and surveillance systems, it is rated with a 1,000,000-hour MTBF and designed for reliable 24/7 performance with carefully managed power consumption.
765466-B21 price is $287.00, a 77.2% saving from the Hpe list price of $1,257.00. 765466-B21 is in stock and available for next-day dispatch. (terms applied)
Request bulk order quote for 765466-B21 for additional pricing. Browse the full Hpe Server 2.5" Hard Drives series or explore all Hpe products.
765466-B21 Specifications
- Product Type
- Hard Drive
- Drive Type
- HDD
- Use Case
- Desktop / Server / NAS / Surveillance / Enterprise Storage
- Interface
- SATA III
- Form Factor
- 3.5-inch
- Storage Capacity
- 4 TB
- Spindle Speed (RPM)
- 7200 RPM
- Cache (Buffer Size)
- 256 MB
- Average Latency
- N/A
- Data Transfer Rate
- Up to 250 MB/s
- Annual Workload Rating
- 550 TB/yr
- Power Consumption (Read/Write)
- 8.5 Watts
- Power Consumption (Idle)
- 5 Watts
- Encryption Support
- AES 256-bit
- Helium Sealed
- Helium-Sealed
- Drive Bays Supported
- Multi-bay
- Vibration Protection
- Yes
- Advanced Features
- Dual Actuator
- Operating Temperature
- 5–55°C
- Product Name
- 765466-B21
- Height
- 1.03 inches
- Width
- 5.79 inches
- Depth
- 4.00 inches
- Weight
- 1.82 lbs
765466-B21 Use Case
Tiered Storage Acceleration for SMB Virtualization
In a small-to-medium business data center running HPE ProLiant DL380 Gen10 servers, IT administrators deploy the 765466-B21-HPE 2TB SAS 12G Midline 7.2K SFF (2.5in) SC 1yr Wty 512e HDD as the nearline tier in an HPE Smart Array P408i-a controller. This configuration offloads cold or infrequently accessed virtual machine images from expensive flash tiers onto high-capacity SAS drives. The result is a 40% reduction in storage spend per VM, consistent 150 MB/s throughput for non-critical workloads, and seamless scalability—while maintaining enterprise-grade reliability backed by a 1-year HPE warranty.
Cost-Efficient Enterprise Backup and Archive Repository
An enterprise backup administrator integrates the 765466-B21-HPE 2TB SAS 12G Midline 7.2K SFF (2.5in) SC 1yr Wty 512e HDD into an HPE StoreOnce R1500 appliance for on-premises disk-to-disk backup and long-term archiving. This midline SAS solution offers 2 TB of high-density capacity per drive at 12 Gb/s throughput, enabling 25% faster daily snapshot retention compared to SATA alternatives. The outcome is a 3× longer retention window, predictable rebuild times under 90 minutes, and a 20% lower total cost of ownership for tiered backup storage.
Shared Media Streaming in Post-Production Environments
A post-production studio deploys the 765466-B21-HPE 2TB SAS 12G Midline 7.2K SFF (2.5in) SC 1yr Wty 512e HDD in an HPE MSA 2050 SAN array to serve as the primary storage for 4K video assets. With guaranteed 12 Gb/s SAS connectivity and 7.2K RPM sustained I/O, editors experience smooth multitrack playback and concurrent render jobs without frame drops. This implementation increases multi-user throughput by 35%, reduces storage rack footprint by 40% versus 3.5-inch drives, and ensures data integrity with enterprise-class error recovery.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table 
| 765466-B21 |  P05924-B21 |  764908-B21 |  P09100-B21 |  794605-B21 | |
|---|---|---|---|---|---|
| Product Type | Hard Drive | Hard Drive | Hard Drive | Hard Drive | Hard Drive |
| Drive Type | HDD | HDD | HDD | HDD | HDD |
| Use Case | Desktop / Server / NAS / Surveillance / Enterprise Storage | Enterprise Storage | Enterprise Storage | Desktop / Server / NAS / Surveillance / Enterprise Storage | Desktop / Server / NAS / Surveillance / Enterprise Storage |
| Interface | SATA III | SATA III | SAS 12Gb/s | SATA III | SATA III |
| Form Factor | 3.5-inch | 3.5-inch | 3.5-inch | 3.5-inch | 3.5-inch |
| Storage Capacity | 4 TB | 4 TB | 4 TB | 8 TB | 4 TB |
| Spindle Speed (RPM) | 7200 RPM | 7200 RPM | 7200 RPM | 7200 RPM | 7200 RPM |
| Cache (Buffer Size) | 256 MB | 128 MB | 256 MB | 256 MB | 256 MB |
| Average Latency | N/A | N/A | N/A | N/A | N/A |
| Data Transfer Rate | Up to 250 MB/s | Up to 250 MB/s | Up to 250 MB/s | Up to 250 MB/s | Up to 210 MB/s |
| Annual Workload Rating | 550 TB/yr | 180 TB/yr | 550 TB/yr | 550 TB/yr | 300 TB/yr |
| Power Consumption (Read/Write) | 8.5 Watts | 8 Watts | 8 Watts | 8.5 Watts | 8 Watts |
| Power Consumption (Idle) | 5 Watts | 4 Watts | 5 Watts | 5.0 Watts | 6 Watts |
| Encryption Support | AES 256-bit | AES 256-bit | AES 256-bit | AES 256-bit | AES 256-bit |
| Helium Sealed | Helium-Sealed | Helium-Sealed | Helium-Sealed | Helium-Sealed | Helium-Sealed |
| Drive Bays Supported | Multi-bay | Multi-bay | Multi-bay | Multi-bay | Multi-bay |
| Vibration Protection | Yes | Yes | Yes | Yes | Yes |
| Advanced Features | Dual Actuator | Dual Actuator | Dual Actuator | Dual Actuator | Dual Actuator |
| Operating Temperature | 5–55°C | 5–60°C | 5–60°C | 5–55°C | 5–60°C |
| Product Name | 765466-B21 | P05924-B21 Enterprise HDD | 764908-B21 Enterprise HDD | P09100-B21 Enterprise HDD | 794605-B21 High Performance Hard Drive |
| Height | 1.03 inches | 1.03 inches | 1.03 inches | 1.03 inches | 1.03 inches |
| Width | 5.79 inches | 5.8 inches | 5.79 inches | 5.8 inches | 5.79 inches |
| Depth | 4.00 inches | 4.0 inches | 4.00 inches | 8.7 inches | 7.78 inches |
| Weight | 1.82 lbs | 2.0 lbs | 3.2 lbs | 1.5 lbs | 2.0 lbs |
Reviews & Ratings
U
Usama Javed
5
Installed in backup infrastructure. No issues during continuous operation.
A
Anna M'ller
4
Stable performance and easy integration with existing systems.
R
Rehan Latif
5
Suitable for less latency-sensitive workloads. Performs consistently.
C
Colin Wright
5
Dependable HPE drive for everyday enterprise storage needs.
Questions & Answers
What is the HPE 2TB SAS 12G Midline 7.2K SFF (2.5in) SC 1yr Wty 512e HDD?
The HPE 2TB SAS 12G Midline 7.2K SFF (2.5in) SC HDD is a 2TB capacity, 12Gb/s SAS interface, 7,200 RPM, 2.5-inch small form factor drive with 512e sectors and a 1-year warranty.
What are the key specifications of this drive?
Key specs include 2TB capacity, 12Gb/s SAS interface, 7,200 RPM, 2.5″ SFF form factor, 512e sector size, single-port connectivity and a 1-year warranty.
Is this HDD compatible with HPE ProLiant servers?
Yes, it’s fully compatible with HPE ProLiant Gen8, Gen9 and Gen10 servers, as well as HPE storage enclosures that support 12Gb/s SAS drives.
What are the benefits of the 12Gb/s SAS interface?
The 12Gb/s SAS interface delivers up to 1.5 GB/s throughput, full-duplex transfer and enhanced reliability for demanding enterprise workloads.
What does 'Midline' mean in this context?
‘Midline’ drives balance cost and capacity for nearline storage, offering moderate performance at a lower price point than enterprise-class drives.
What is 512e sector size and why is it important?
512e emulates 512-byte sectors on 4K native platters, ensuring broad OS compatibility while improving storage efficiency and capacity utilization.
What warranty coverage does this HDD include?
This drive includes a 1-year HPE warranty covering defects in materials and workmanship, with optional warranty extensions available.
How do I install the HPE 2TB SAS 12G Midline HDD?
Insert the drive into any HPE 2.5″ SAS bay—it's hot-swappable—and the HPE Smart Array controller auto-configures it on boot.
What are typical use cases for this HDD?
Ideal use cases include backup, archiving, sequential data storage and write-intensive midline workloads requiring high capacity.
What performance can I expect from this HDD?
You can achieve sustained sequential transfers up to 205 MB/s and an average latency of 4.16 ms for midline applications.
How can I monitor the drive’s health?
Use HPE Integrated Lights-Out (iLO) or the HPE Smart Storage Administrator to view S.M.A.R.T. metrics and predictive failure alerts.
What form factor does this HDD use?
The drive uses a 2.5-inch small form factor (SFF), fitting standard 2.5″ SAS bays in HPE servers and storage arrays.
Can I use this HDD in RAID configurations?
Yes, it supports hardware RAID levels 0, 1, 5, 6, 10, 50 and 60 via HPE Smart Array controllers for enhanced data protection.
What is the drive’s MTBF rating?
This HDD is rated for 1.2 million hours Mean Time Between Failures (MTBF), ensuring high reliability for midline storage.
Which operating systems are supported?
The drive is compatible with major operating systems including Microsoft Windows Server, Linux distributions and VMware ESXi.
How do I replace an existing drive with this model?
Power off or enter drive-fail mode, unlock the tray, slide out the old drive, insert the new HDD until it clicks, then rebuild via your RAID controller.