Server Processors HPE ML110
HPE ML110 server processors deliver robust performance, reliability, and scalability for data centers and enterprise applications. These processors enhance virtualization, streamline IT operations, and secure mission-critical workloads.
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826106-L21 (HPE ML110 Gen9 E5-1603v4 FIO Kit)
4.4 (5)- Processors
- Intel
- Intel Core
- Desktop
- 128 GB
- DDR4 & DDR5
- Intel 12th Gen
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826107-L21 (HPE ML110 Gen9 E5-1620v4 FIO Kit)
4.6 (5)- Processors
- AMD
- AMD Ryzen
- Desktop
- 128 GB
- DDR4
- Ryzen 5000 Series
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826108-L21 (HPE ML110 Gen9 E5-1607v4 FIO Kit)
4.6 (5)- Processors
- Intel
- Intel Core
- Desktop
- 128 GB
- DDR4 & DDR5
- Intel 13th Gen
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826110-L21 (HPE ML110 Gen9 E5-1660v4 FIO Kit)
4.4 (5)- Processors
- Intel
- Intel Core
- Desktop
- 128 GB
- DDR5
- Intel 13th Gen
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826111-L21 (HPE ML110 Gen9 E5-1680v4 FIO Kit)
4.6 (5)- Processors
- Intel
- Intel Core
- Desktop
- 128 GB
- DDR4
- Intel 11th Gen
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- FEARURED

826099-L21 (HPE ML110 Gen9 E5-2660v4 FIO Kit)
4.8 (5)- Processors
- Intel
- Intel Core
- Desktop
- 128 GB
- DDR4 & DDR5
- Intel 13th Gen
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876916-L21 (HPE ML110 Gen10 Xeon-B 3106 FIO Kit)
4.4 (5)- Processors
- Intel
- Intel Core
- Desktop
- 128 GB
- DDR4 & DDR5
- Intel 13th Gen
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826100-L21 (HPE ML110 Gen9 E5-2640v4 FIO Kit)
4.4 (5)- Processors
- Intel
- Intel Core
- Desktop
- 128 GB
- DDR5
- Intel 13th Gen
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876917-L21 (HPE ML110 Gen10 Xeon-S 4108 FIO Kit)
4.8 (5)- Processors
- Intel
- Intel Core
- Desktop
- 128 GB
- DDR4 & DDR5
- Intel 13th Gen
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826101-L21 (HPE ML110 Gen9 E5-2620v4 FIO Kit)
5 (5)- Processors
- Intel
- Intel Core
- Desktop
- 128 GB
- DDR4 & DDR5
- Intel 12th Gen
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876918-L21 (HPE ML110 Gen10 Xeon-S 4110 FIO Kit)
4.4 (5)- Processors
- Intel
- Intel Core
- Desktop
- 128 GB
- DDR4 & DDR5
- Intel 13th Gen
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826102-L21 (HPE ML110 Gen9 E5-2609v4 FIO Kit)
4.6 (5)- Processors
- Intel
- Intel Core
- Desktop
- 128 GB
- DDR5
- Intel 13th Gen
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872298-L21 (HPE ML110 Gen10 Xeon-S 4114 FIO Kit)
4.8 (5)- Processors
- Intel
- Intel Core
- Desktop
- 128 GB
- DDR5
- Intel 13th Gen
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826103-L21 (HPE ML110 Gen9 E5-2603v4 FIO Kit)
4.2 (5)- Processors
- Intel
- Intel Core
- Desktop
- 128 GB
- DDR4 & DDR5
- Intel 13th Gen
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872302-L21 (HPE ML110 Gen10 Xeon-G 5115 FIO Kit)
4.4 (5)- Processors
- Intel
- Intel Core
- Desktop
- 128 GB
- DDR4 & DDR5
- Intel 12th Gen
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826104-L21 (HPE ML110 Gen9 E5-2630Lv4 FIO Kit)
4.8 (5)- Processors
- Intel
- Intel Core
- Desktop
- 128 GB
- DDR5
- Intel 13th Gen
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826105-L21 (HPE ML110 Gen9 E5-2623v4 FIO Kit)
4.2 (5)- Processors
- Intel
- Intel Core
- Desktop
- 128 GB
- DDR5
- Intel 13th Gen
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872296-L21 (HPE ML110 Gen10 Xeon-S 4112 FIO Kit)
5 (5)- Processors
- Intel
- Intel Core
- Desktop
- 128 GB
- DDR4 & DDR5
- Intel 12th Gen
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872306-L21 (HPE ML110 Gen10 Xeon-G 5120 FIO Kit)
4.8 (5)- Processors
- Intel
- Intel Core
- Desktop
- 128 GB
- DDR5
- Intel 13th Gen
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872308-L21 (HPE ML110 Gen10 Xeon-G 5122 FIO Kit)
4.6 (5)- Processors
- Intel
- Intel Core
- Desktop
- 128 GB
- DDR4 & DDR5
- Intel 13th Gen
Est ValueFirst-Time Buyer Discount – Get up to 2% additional off on your first order
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Questions & Answers
What processors are compatible with HPE ProLiant ML110 Gen10 servers?
HPE ML110 Gen10 servers support Intel Xeon Scalable 1st and 2nd Gen processors (Bronze, Silver, Gold, Platinum) with up to 16 cores and 205W TDP for enterprise-grade performance.
How many CPU sockets does the HPE ML110 Gen10 server support?
The HPE ML110 Gen10 features a single LGA 3647 CPU socket, enabling installation of one Intel Xeon Scalable processor for simplified upgrade paths and predictable scaling.
What is the maximum CPU core count for HPE ML110 Gen10?
When equipped with Intel Xeon Platinum 8280 or equivalent 2nd Gen CPUs, the ML110 Gen10 can deliver up to 28 cores (56 threads) for intensive virtualization and compute tasks.
What is the maximum Turbo Boost frequency on ML110 Gen10 processors?
ML110 Gen10 supports Intel Turbo Boost Technology up to 4.3 GHz on select Xeon Scalable 2nd Gen models, dynamically accelerating core-level performance during peak workloads.
What thermal design power (TDP) ratings does HPE ML110 Gen10 support?
The ML110 Gen10 is validated for Intel Xeon Scalable processors with TDP ratings up to 205 W, ensuring compatibility with high-performance CPUs while maintaining proper cooling.
Does HPE ML110 Gen10 support Hyper-Threading and virtualization technologies?
Yes. ML110 Gen10 fully supports Intel Hyper-Threading Technology, Intel VT-x, and Intel VT-d, delivering enhanced thread‐level parallelism and secure virtualization for VMs.
Can I upgrade the processor in my HPE ML110 Gen10 server?
You can upgrade to any supported Intel Xeon Scalable 1st or 2nd Gen processor within the server’s 205 W TDP limit, provided you apply the latest HPE Service Pack for ProLiant (SPP) firmware.
What memory types work with HPE ML110 Gen10 processors?
ML110 Gen10 supports DDR4 RDIMMs or LRDIMMs at up to 2933 MT/s, with four DIMM slots per CPU enabling configurations from 16 GB up to 512 GB of ECC-protected memory.
What is the difference between ML110 Gen9 and Gen10 processor support?
ML110 Gen9 uses Intel Xeon E5-2600 v3/v4 CPUs (LGA 2011-3), whereas Gen10 upgrades to Intel Xeon Scalable 1st/2nd Gen (LGA 3647), offering higher core counts, faster memory, and advanced security features.
Does HPE ML110 Gen10 support AMD EPYC processors?
No. The HPE ML110 Gen10 platform is engineered exclusively for Intel Xeon Scalable processors and does not support AMD EPYC CPU architectures.
How do I update the CPU microcode on an HPE ML110 Gen10 server?
Download and install the latest HPE Service Pack for ProLiant (SPP) ISO to update CPU microcode, firmware, and BIOS, ensuring optimal stability and vulnerability mitigation.
What power supply options are available for HPE ML110 Gen10 with high-TDP CPUs?
ML110 Gen10 offers 350 W and 500 W Flex Slot power supplies to support processors up to 205 W TDP, with optional redundant PSU configurations for high availability.
Are integrated graphics available on HPE ML110 Gen10 processors?
Intel Xeon Scalable CPUs in ML110 Gen10 do not include integrated GPUs. The server uses a Matrox G200 video controller for basic management and remote console operations.
What warranty covers the processors in HPE ML110 Gen10 servers?
Processors in the ML110 Gen10 come with HPE’s standard three-year parts, labor, and on-site warranty, with optional Care Pack upgrades for extended support and fast response.
How many DIMM slots can I populate for optimized CPU memory performance?
The ML110 Gen10 provides four DIMM slots per CPU socket, supporting balanced dual-channel memory configurations for maximum bandwidth and reduced latency.
What security features do HPE ML110 Gen10 processors provide?
Intel Xeon Scalable 2nd Gen processors in ML110 Gen10 include Intel SGX for enclave security, Intel OS Guard, and Secure Boot, protecting firmware and kernel against unauthorized code execution.