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P00880-B21
HPE DL580 Gen10 Intel Xeon-Gold 6143 (2.8GHz/16-core/205W) P...
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P00880-B21 is a high-performance AMD Ryzen 5000 Series processor that features 8 cores and 16 threads engineered on the Zen 3 architecture. Designed for the AM4 socket, this processor delivers robust computing with a base clock of 3.8 GHz and a boost clock of 4.6 GHz, backed by 4 MB of L2 cache and 32 MB of L3 cache, all within a 105W thermal design power envelope.
P00880-B21 supports dual-channel DDR4 memory and PCIe 4.0 connectivity while offering unlocked overclocking capabilities, making it ideal for both gaming and workstation scenarios. Although it lacks integrated graphics, its design aligns well with high-end system builds and modern chipsets, ensuring platform compatibility for enthusiasts and professional users alike.
P00880-B21 price is is available on request. Get immediate quote.
Request bulk order quote for P00880-B21 for additional pricing. Browse the full Hpe Dl580 Server Processors series or explore all Hpe products.
A global financial services firm deploys the P00880-B21 HPE DL580 Gen10 with Intel Xeon-Gold 6143 to consolidate 150+ VMs onto four chassis, reducing rack footprint by 40% and power draw by 30%. Outcome: 3:1 VM consolidation ratio, 30% lower TCO and sustained enterprise-grade performance.
A national retail chain runs a 500 TB SAP HANA cluster on the P00880-B21 HPE DL580 Gen10 with Intel Xeon-Gold 6143, handling sub-second inventory updates across 2,000 stores. Outcome: 20% faster stock replenishment, improved demand forecasting accuracy, and enhanced customer satisfaction.
A university research center harnesses the P00880-B21 HPE DL580 Gen10 with Intel Xeon-Gold 6143 to execute large-scale CFD and FEA workloads. By leveraging 16 cores per socket and advanced memory bandwidth, simulation runtimes drop from 72 to 24 hours. Outcome: 3× throughput improvement, faster innovation cycles, and deeper modeling insights.
To get the detailed certification, please go to the Compliance Center.
| Architecture | Zen 3 | Raptor Lake | Raptor Lake | Raptor Lake | Alder Lake |
| Base Clock | 3.8 | 3.4 GHz | 3.8 GHz | 3.6 GHz | 3.6 |
| Brand | AMD | Intel | Intel | Intel | Intel |
| CPU Socket | AM4 | LGA 1700 | LGA 1700 | LGA 1700 | LGA 1700 |
| Category | Desktop | Desktop | Desktop | Desktop | Desktop |
| Cooler Included | Yes | No | No | No | No |
| Cores | 8 | 16 | 16 | 8 | 12 |
| Depth | 1.0 | N/A | 1.5 inches | N/A | N/A |
| ECC Support | No | No | No | No | No |
| Generation | Ryzen 5000 Series | Intel 13th Gen | Intel 13th Gen | Intel 13th Gen | Intel 12th Gen |
| Graphics Base Frequency | N/A | 350 MHz | 350 MHz | 350 MHz | 350 |
| Graphics Max Dynamic Frequency | N/A | 1300 MHz | 1200 MHz | 1200 MHz | 1200 |
| Height | 1.5 | N/A | 0.6 inches | N/A | N/A |
| Instruction Set Extensions | AVX2 | AVX2 | AVX2 | AVX2 | AVX2 |
| Integrated Graphics | None | Intel UHD Graphics 770 | Intel UHD Graphics 770 | Intel UHD Graphics 770 | Intel UHD Graphics 770 |
| L2 Cache | 4 | 1.5 MB | 16 MB | 4 MB | 12 |
| L3 Cache | 32 | 30 MB | 30 MB | 16 MB | 20 |
| Max Boost Clock | 4.6 | 5.4 GHz | 5.0 GHz | 5.0 GHz | 4.9 |
| Max Memory Support | 128 GB | 128 GB | 128 GB | 128 GB | 128 GB |
| Memory Channels | Dual | Dual | Dual | Dual | Dual |
| Memory Type Support | DDR4 | DDR4 & DDR5 | DDR5 | DDR4 & DDR5 | DDR4 & DDR5 |
| Overclocking Support | Yes | Yes | Yes | Yes | Yes |
| PCIe Version | PCIe 4.0 | PCIe 5.0 | PCIe 5.0 | PCIe 5.0 | PCIe 5.0 |
| Product Name | P00880-B21 | 878144-L21 | P05704-L21 High Performance Desktop Processor | Intel Core i7-13700K | 878133-B21 |
| Product Type | Processors | Processors | Processors | Processors | Processors |
| Security Features | None | None | SGX | None | SGX |
| Series | AMD Ryzen | Intel Core | Intel Core | Intel Core | Intel Core |
| TDP | 105W | 125W | 125W | 125W | 125W |
| Threads | 16 | 24 | 24 | 16 | 20 |
| Unlocked | Yes | Yes | Yes | Yes | Yes |
| Use Case | Gaming / Workstation | Gaming | Gaming / Workstation | Gaming | Gaming |
| Virtualization Support | AMD-V | Intel VT-x / Intel VT-d | Intel VT-x | Intel VT-x | Intel VT-x |
| Weight | 0.25 | N/A | 0.25 lbs | N/A | N/A |
| Width | 1.5 | N/A | 1.5 inches | N/A | N/A |
The Xeon Gold 6143 delivered reliable multi-core performance.
Handled virtualization and analytics smoothly.
Stable performance under sustained load.
No issues in production environment.
Solid enterprise-grade processor.
The HPE DL580 Gen10 Intel Xeon-Gold 6143 Processor Kit (P00880-B21) delivers 16 cores/32 threads at 2.8 GHz base and up to 3.7 GHz Turbo, 24.75 MB L3 cache, 205 W TDP and DDR4 SmartMemory support in the ProLiant DL580 Gen10.
This processor kit is compatible exclusively with the HPE ProLiant DL580 Gen10 server platform, ensuring optimized performance and full feature support.
The Intel Xeon-Gold 6143 delivers 16 physical cores and 32 threads to handle high-density virtualization and parallel compute workloads.
The processor runs at a 2.8 GHz base frequency and accelerates up to 3.7 GHz with Intel Turbo Boost Technology for burst performance.
This CPU has a 205 W TDP, balancing high performance with enterprise-class cooling requirements in the DL580 Gen10 chassis.
It features 24.75 MB of shared L3 cache to accelerate data access, reduce latency and improve multi-threaded performance.
It supports DDR4 SmartMemory ECC DIMMs at up to 2666 MT/s across six memory channels, enabling a maximum capacity of 6 TB in the DL580 Gen10.
Yes, it includes Intel VT-x and VT-d for hardware-accelerated virtualization, secure partitioning and efficient resource management.
With its high core count, fast clock speeds and large cache, it significantly boosts compute-intensive, database and virtualization workloads on the DL580 Gen10.
Compared to the Gen9 lineup, it delivers higher core density, faster DDR4 support, increased cache and advanced security features like Intel SGX and AES-NI.
Yes, it installs directly into the DL580 Gen10 CPU socket and is auto-detected by HPE iLO for seamless firmware alignment and configuration.
HPE offers a one-year limited warranty with global three-year electronic support and optional on-site warranties up to five years through HPE Services.
Regular iLO firmware and UEFI updates are recommended to maintain compatibility, security and peak performance on the DL580 Gen10 platform.
It excels in virtualization, large-scale databases, in-memory analytics and enterprise applications that demand high core counts and memory bandwidth.
Yes, it fully integrates with HPE OneView and Integrated Lights-Out (iLO) for proactive health monitoring, remote management and automated firmware updates.
By delivering higher performance per core and energy-efficient design, it reduces server consolidation needs and lowers operational costs over its lifecycle.