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P00880-B21
HPE DL580 Gen10 Intel Xeon-Gold 6143 (2.8GHz/16-core/205W) P...
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P00880-B21 is a high-performance AMD Ryzen 5000 Series processor that features 8 cores and 16 threads engineered on the Zen 3 architecture. Designed for the AM4 socket, this processor delivers robust computing with a base clock of 3.8 GHz and a boost clock of 4.6 GHz, backed by 4 MB of L2 cache and 32 MB of L3 cache, all within a 105W thermal design power envelope.
P00880-B21 supports dual-channel DDR4 memory and PCIe 4.0 connectivity while offering unlocked overclocking capabilities, making it ideal for both gaming and workstation scenarios. Although it lacks integrated graphics, its design aligns well with high-end system builds and modern chipsets, ensuring platform compatibility for enthusiasts and professional users alike.
P00880-B21 price is is available on request. Get immediate quote.
Request bulk order quote for P00880-B21 for additional pricing. Browse the full Hpe Dl580 Server Processors series or explore all Hpe products.
A global financial services firm deploys the P00880-B21 HPE DL580 Gen10 with Intel Xeon-Gold 6143 to consolidate 150+ VMs onto four chassis, reducing rack footprint by 40% and power draw by 30%. Outcome: 3:1 VM consolidation ratio, 30% lower TCO and sustained enterprise-grade performance.
A national retail chain runs a 500 TB SAP HANA cluster on the P00880-B21 HPE DL580 Gen10 with Intel Xeon-Gold 6143, handling sub-second inventory updates across 2,000 stores. Outcome: 20% faster stock replenishment, improved demand forecasting accuracy, and enhanced customer satisfaction.
A university research center harnesses the P00880-B21 HPE DL580 Gen10 with Intel Xeon-Gold 6143 to execute large-scale CFD and FEA workloads. By leveraging 16 cores per socket and advanced memory bandwidth, simulation runtimes drop from 72 to 24 hours. Outcome: 3× throughput improvement, faster innovation cycles, and deeper modeling insights.
To get the detailed certification, please go to the Compliance Center.
| Product Type | Processors | Processors | Processors | Processors | Processors |
| Brand | AMD | Intel | Intel | Intel | Intel |
| Series | AMD Ryzen | Intel Core | Intel Core | Intel Core | Intel Core |
| Category | Desktop | Desktop | Desktop | Desktop | Desktop |
| Max Memory Support | 128 GB | 128 GB | 128 GB | 128 GB | 128 GB |
| Memory Type Support | DDR4 | DDR4 & DDR5 | DDR5 | DDR4 & DDR5 | DDR4 & DDR5 |
| Generation | Ryzen 5000 Series | Intel 13th Gen | Intel 13th Gen | Intel 13th Gen | Intel 12th Gen |
| Architecture | Zen 3 | Raptor Lake | Raptor Lake | Raptor Lake | Alder Lake |
| ECC Support | No | No | No | No | No |
| Security Features | None | None | SGX | None | SGX |
| CPU Socket | AM4 | LGA 1700 | LGA 1700 | LGA 1700 | LGA 1700 |
| Instruction Set Extensions | AVX2 | AVX2 | AVX2 | AVX2 | AVX2 |
| Virtualization Support | AMD-V | Intel VT-x / Intel VT-d | Intel VT-x | Intel VT-x | Intel VT-x |
| Cores | 8 | 16 | 16 | 8 | 12 |
| Threads | 16 | 24 | 24 | 16 | 20 |
| Base Clock | 3.8 | 3.4 GHz | 3.8 GHz | 3.6 GHz | 3.6 |
| Max Boost Clock | 4.6 | 5.4 GHz | 5.0 GHz | 5.0 GHz | 4.9 |
| Overclocking Support | Yes | Yes | Yes | Yes | Yes |
| L2 Cache | 4 | 1.5 MB | 16 MB | 4 MB | 12 |
| L3 Cache | 32 | 30 MB | 30 MB | 16 MB | 20 |
| TDP | 105W | 125W | 125W | 125W | 125W |
| Integrated Graphics | None | Intel UHD Graphics 770 | Intel UHD Graphics 770 | Intel UHD Graphics 770 | Intel UHD Graphics 770 |
| Graphics Base Frequency | N/A | 350 MHz | 350 MHz | 350 MHz | 350 |
| Graphics Max Dynamic Frequency | N/A | 1300 MHz | 1200 MHz | 1200 MHz | 1200 |
| Memory Channels | Dual | Dual | Dual | Dual | Dual |
| PCIe Version | PCIe 4.0 | PCIe 5.0 | PCIe 5.0 | PCIe 5.0 | PCIe 5.0 |
| Unlocked | Yes | Yes | Yes | Yes | Yes |
| Cooler Included | Yes | No | No | No | No |
| Use Case | Gaming / Workstation | Gaming | Gaming / Workstation | Gaming | Gaming |
| Product Name | P00880-B21 | 878144-L21 | P05704-L21 High Performance Desktop Processor | Intel Core i7-13700K | 878133-B21 |
| Height | 1.5 | N/A | 0.6 inches | N/A | N/A |
| Width | 1.5 | N/A | 1.5 inches | N/A | N/A |
| Depth | 1.0 | N/A | 1.5 inches | N/A | N/A |
| Weight | 0.25 | N/A | 0.25 lbs | N/A | N/A |
The Xeon Gold 6143 delivered reliable multi-core performance.
Handled virtualization and analytics smoothly.
Stable performance under sustained load.
No issues in production environment.
Solid enterprise-grade processor.
The HPE DL580 Gen10 Intel Xeon-Gold 6143 Processor Kit (P00880-B21) delivers 16 cores/32 threads at 2.8 GHz base and up to 3.7 GHz Turbo, 24.75 MB L3 cache, 205 W TDP and DDR4 SmartMemory support in the ProLiant DL580 Gen10.
This processor kit is compatible exclusively with the HPE ProLiant DL580 Gen10 server platform, ensuring optimized performance and full feature support.
The Intel Xeon-Gold 6143 delivers 16 physical cores and 32 threads to handle high-density virtualization and parallel compute workloads.
The processor runs at a 2.8 GHz base frequency and accelerates up to 3.7 GHz with Intel Turbo Boost Technology for burst performance.