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P02465-B21
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- HPE ProLiant DL380 Gen10 5218 2.3GHz 16-core 2P 64GB-R P408i-a 8SFF 800W PS Server
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P02465-B21 Overview
P02465-B21 is a high-performance rackmount server featuring support for Intel Xeon Scalable processors in an LGA 4189 socket, engineered for a 2P (dual processor) configuration. Designed for intensive workloads, it supports ECC DDR4 memory with up to 512 GB total capacity, ensuring reliable performance for virtualization, file serving, and application hosting.
This model includes 8 hot-swap drive bays sized for 2.5-inch drives and offers robust RAID 10 protection, along with 4 PCIe 4.0 expansion slots and integrated 10GbE network interfaces. It is equipped with redundant 800W power supplies, active cooling, and comprehensive remote management via iDRAC, making it ideally suited for modern data centers and enterprise-grade deployments.
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P02465-B21 Specifications
| Product Type | Server |
| Form Factor | Rackmount |
| Rack Units | 2U |
| Processor Brand | Intel |
| Processor Series | Intel Xeon Scalable |
| Processor Generation | Xeon 3rd Gen |
| Use Case | Virtualization |
| CPU Socket | LGA 4189 |
| Scalability | 2P |
| Max Cores Per CPU | 32 |
| Max Threads Per CPU | 64 |
| RAM Type | ECC DDR4 |
| RAM Slots | 8 |
| Max RAM Capacity | 512 GB |
| Storage Type | SATA SSD |
| Storage Bays | 8 |
| Drive Bay Size | 2.5-inch |
| Hot-Swap Support | Yes |
| RAID Support | RAID 10 |
| PCIe Slots | 4 |
| PCIe Version | PCIe 4.0 |
| Network Interface | 10GbE |
| LAN Ports | 4 |
| Remote Management | iDRAC |
| Power Supply | Redundant |
| Power Supply Wattage | 800W |
| Cooling | Active |
| Operating System | VMware ESXi |
| Virtualization Ready | Yes |
| GPU Support | Yes |
| Rail Kit Included | Yes |
| Product Name | P02465-B21 Enterprise Server |
| Height | 3.5 |
| Width | 19 |
| Depth | 27 |
| Weight | 45 |
P02465-B21 Use Case
High-Density Enterprise Virtualization for Private Cloud
In a global financial services data center, the P02465-B21 HPE ProLiant DL380 Gen10 5218 (2.3 GHz, 16-core × 2) with 64 GB RAM and P408i-a RAID powers a VMware vSphere cluster. By consolidating 50+ Linux® and Windows® VMs onto eight-bay SFF storage, the deployment cuts rack footprint by 60%, reduces power draw by 40%, and accelerates VM provisioning to under 30 seconds—delivering secure multi-tenant isolation, predictable performance, and 99.99% uptime.
Secure Virtual Desktop Infrastructure (VDI) for Enterprise Workforces
A multinational retail chain leverages the P02465-B21 HPE ProLiant DL380 Gen10 server to host Citrix® Virtual Apps and Desktops. Dual 16-core CPUs, 64 GB RAM, and an 8-SFF chassis with 800 W Platinum power supplies deliver sub-100 ms login times for 200 concurrent users. Outcome: streamlined IT management with HPE OneView, 50% lower TCO versus legacy blades, and end-to-end encryption meeting PCI DSS standards for retail point-of-sale environments.
Real-Time Analytics and In-Memory Database Acceleration
In a subscription-based media platform, the P02465-B21 HPE ProLiant DL380 Gen10 accelerates SAP® HANA® in-memory workloads. Equipped with dual 16-core processors, 64 GB RAM, and P408i-a caching, the server sustains 2M+ transactions per minute and sub-millisecond database queries. Benefit: 70% faster content personalization, seamless scale-out for peak viewing periods, and 24×7 availability backed by HPE Integrated Lights-Out (iLO) remote monitoring—driving subscriber engagement and revenue growth.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table
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| Cooling | Active | Active | Active | Active | Active |
| CPU Socket | LGA 4189 | LGA 4677 | LGA 4189 | LGA 4189 | LGA 4189 |
| Depth | 28 inches | 28 inches | 28 inches | 27 | 28.7 inches |
| Drive Bay Size | 2.5-inch | 2.5-inch | 2.5-inch | 2.5-inch | 3.5-inch |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | Yes | Yes | Yes | Yes | No |
| Height | 3.4 inches | 3.5 inches | 3.5 inches | 3.5 | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 4 | 4 | 2 | 4 | 2 |
| Max Cores per CPU | 64 | 32 | 32 | 32 | 32 |
| Max RAM Capacity | 512 GB | 1 TB | 1 TB | 512 GB | 1 TB |
| Max Threads per CPU | 128 | 64 | 64 | 64 | 64 |
| Network Interface | 10GbE | 10GbE | 10GbE | 10GbE | 10GbE |
| Operating System | Windows Server | VMware ESXi | Windows Server | VMware ESXi | VMware ESXi |
| PCIe Slots | 4 | 4 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 800W | 1000W | 800W | 800W | 750W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 3rd Gen | Xeon 4th Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | P19720-B21 | 767033-B21 Enterprise Rackmount Server | 810393-B21 | P02465-B21 Enterprise Server | 776318-B21 |
| Product Type | Server | Server | Server | Server | Server |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| RAID Support | RAID 10 | RAID 10 | RAID 10 | RAID 10 | RAID 10 |
| Rail Kit Included | No | Yes | No | Yes | Yes |
| RAM Slots | 16 | 8 | 16 | 8 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 8 | 8 | 8 | 8 |
| Storage Type | SATA SSD | NVMe SSD | NVMe SSD | SATA SSD | SATA HDD |
| Use Case | Virtualization / File Server / Application Server | Virtualization | Virtualization | Virtualization | Virtualization |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 45 lbs | 45 lbs | 60 lbs | 45 | 45 lbs |
| Width | 17.2 inches | 19 inches | 17.5 inches | 19 | 17.3 inches |
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Questions & Answers
Q
What are the key specifications of the HPE ProLiant DL380 Gen10 SKU P02465-B21?
A
The HPE ProLiant DL380 Gen10 SKU P02465-B21 includes dual Intel Xeon Silver 5218 processors (2.3 GHz, 16 cores each), 64 GB DDR4-R memory, HPE Smart Array P408i-a RAID controller, eight SFF drive bays, and an 800 W power supply.
Q
How many processors and cores does the P02465-B21 server support?
A
This server supports two Intel Xeon Silver 5218 processors, delivering a total of 32 physical cores and 64 threads for high-performance computing.
Q
What type and amount of memory is included in the P02465-B21?
A
The P02465-B21 ships with 64 GB of DDR4-Registered memory (4 x 16 GB RDIMMs) running at up to 2933 MT/s, expandable up to 3 TB using 24 DIMM slots.
Q
What RAID controller is integrated into this server?
A
This model features the HPE Smart Array P408i-a SR Gen10 Controller, offering hardware RAID levels 0, 1, 5, 6, 10, 50, and 60 for enhanced data protection.
Q
How many drive bays and what form factor does it support?
A
The DL380 Gen10 P02465-B21 includes eight Small Form Factor (2.5") hot-plug drive bays and supports optional expansion up to 24 SFF or 12 LFF bays.
Q
What is the power supply configuration of the P02465-B21?
A
This server is equipped with a single 800 W Flexible Slot Platinum Hot Plug power supply, with optional redundant or higher-wattage units available.
Q
Which operating systems are compatible with the P02465-B21?
A
The P02465-B21 is certified for Windows Server, Red Hat Enterprise Linux, SUSE Linux Enterprise Server, VMware ESXi, and other major enterprise operating systems.
Q
Can the P02465-B21 be used for virtualization workloads?
A
Yes, with dual 16-core CPUs, large memory capacity, and HPE Virtualization Licensing options, this server is ideal for VMware, Hyper-V, and containerized environments.
Q
What network connectivity options are available?
A
The server includes four embedded 1 GbE network ports and supports optional FlexibleLOM or PCIe network adapters for 10/25/40/100 GbE connectivity.
Q
How scalable is the storage on this server?
A
You can scale storage via eight standard SFF bays plus additional optional drive cages, support for NVMe drives, and external HPE MSA or 3PAR arrays.
Q
What management tools are included for remote administration?
A
The P02465-B21 features HPE Integrated Lights-Out (iLO) 5 for agentless remote management, monitoring, firmware updates, and RESTful API integration.
Q
What is the warranty and support coverage for this SKU?
A
HPE ProLiant DL380 Gen10 P02465-B21 comes with a standard three-year, next-business-day parts replacement warranty, with optional HPE Foundation Care and Proactive Care services.
Q
How energy efficient is the HPE ProLiant DL380 Gen10?
A
This server uses HPE Platinum efficiency power supplies, advanced thermal design, and HPE Sea of Sensors technology to optimize power consumption and cooling.
Q
What expansion options are available for additional PCIe cards?
A
The chassis offers up to six PCIe Gen4 slots, supporting GPUs, NVMe RAID adapters, network cards, and storage controllers for customized performance.
Q
How do I upgrade the memory or storage on the P02465-B21?
A
Upgrades are simple: insert additional DDR4 RDIMMs into empty slots and add or replace drives in the hot-plug bays; no tools are required thanks to the tool-less design.
Q
Where can I purchase spare parts or additional components?
A
Genuine HPE spare parts and accessories for the DL380 Gen10 P02465-B21 are available through authorized HPE resellers or the HPE Parts Store online.