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Hugh Callahan
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Dual processor setup delivers strong virtualization performance.
P02465-B21
HPE ProLiant DL380 Gen10 5218 2.3GHz 16-core 2P 64GB-R P408i...
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P02465-B21
- Description:
- HPE ProLiant DL380 Gen10 5218 2.3GHz 16-core 2P 64GB-R P408i-a 8SFF 800W PS Server
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P02465-B21 Overview
P02465-B21 is a high-performance rackmount server featuring support for Intel Xeon Scalable processors in an LGA 4189 socket, engineered for a 2P (dual processor) configuration. Designed for intensive workloads, it supports ECC DDR4 memory with up to 512 GB total capacity, ensuring reliable performance for virtualization, file serving, and application hosting.
This model includes 8 hot-swap drive bays sized for 2.5-inch drives and offers robust RAID 10 protection, along with 4 PCIe 4.0 expansion slots and integrated 10GbE network interfaces. It is equipped with redundant 800W power supplies, active cooling, and comprehensive remote management via iDRAC, making it ideally suited for modern data centers and enterprise-grade deployments.
P02465-B21 price is is available on request. Get immediate quote.
Request bulk order quote for P02465-B21 for additional pricing. Browse the full Hpe Proliant Dl380 Gen10 Servers series or explore all Hpe products.
P02465-B21 Specifications
- Product Type
- Server
- Form Factor
- Rackmount
- Rack Units
- 2U
- Processor Brand
- Intel
- Processor Series
- Intel Xeon Scalable
- Processor Generation
- Xeon 3rd Gen
- Use Case
- Virtualization
- CPU Socket
- LGA 4189
- Scalability
- 2P
- Max Cores per CPU
- 32
- Max Threads per CPU
- 64
- RAM Type
- ECC DDR4
- RAM Slots
- 8
- Max RAM Capacity
- 512 GB
- Storage Type
- SATA SSD
- Storage Bays
- 8
- Drive Bay Size
- 2.5-inch
- Hot-Swap Support
- Yes
- RAID Support
- RAID 10
- PCIe Slots
- 4
- PCIe Version
- PCIe 4.0
- Network Interface
- 10GbE
- LAN Ports
- 4
- Remote Management
- iDRAC
- Power Supply
- Redundant
- Power Supply Wattage
- 800W
- Cooling
- Active
- Operating System
- VMware ESXi
- Virtualization Ready
- Yes
- GPU Support
- Yes
- Rail Kit Included
- Yes
- Product Name
- P02465-B21 Enterprise Server
- Height
- 3.5
- Width
- 19
- Depth
- 27
- Weight
- 45
P02465-B21 Use Case
High-Density Enterprise Virtualization for Private Cloud
In a global financial services data center, the P02465-B21 HPE ProLiant DL380 Gen10 5218 (2.3 GHz, 16-core × 2) with 64 GB RAM and P408i-a RAID powers a VMware vSphere cluster. By consolidating 50+ Linux® and Windows® VMs onto eight-bay SFF storage, the deployment cuts rack footprint by 60%, reduces power draw by 40%, and accelerates VM provisioning to under 30 seconds—delivering secure multi-tenant isolation, predictable performance, and 99.99% uptime.
Secure Virtual Desktop Infrastructure (VDI) for Enterprise Workforces
A multinational retail chain leverages the P02465-B21 HPE ProLiant DL380 Gen10 server to host Citrix® Virtual Apps and Desktops. Dual 16-core CPUs, 64 GB RAM, and an 8-SFF chassis with 800 W Platinum power supplies deliver sub-100 ms login times for 200 concurrent users. Outcome: streamlined IT management with HPE OneView, 50% lower TCO versus legacy blades, and end-to-end encryption meeting PCI DSS standards for retail point-of-sale environments.
Real-Time Analytics and In-Memory Database Acceleration
In a subscription-based media platform, the P02465-B21 HPE ProLiant DL380 Gen10 accelerates SAP® HANA® in-memory workloads. Equipped with dual 16-core processors, 64 GB RAM, and P408i-a caching, the server sustains 2M+ transactions per minute and sub-millisecond database queries. Benefit: 70% faster content personalization, seamless scale-out for peak viewing periods, and 24×7 availability backed by HPE Integrated Lights-Out (iLO) remote monitoring—driving subscriber engagement and revenue growth.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table
 P02465-B21 |  767033-B21 |  776318-B21 |  810393-B21 |  P19720-B21 | |
|---|---|---|---|---|---|
| CPU Socket | LGA 4189 | LGA 4677 | LGA 4189 | LGA 4189 | LGA 4189 |
| Cooling | Active | Active | Active | Active | Active |
| Depth | 27 | 28 inches | 28.7 inches | 28 inches | 28 inches |
| Drive Bay Size | 2.5-inch | 2.5-inch | 3.5-inch | 2.5-inch | 2.5-inch |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | Yes | Yes | No | Yes | Yes |
| Height | 3.5 | 3.5 inches | 3.5 inches | 3.5 inches | 3.4 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 4 | 4 | 2 | 2 | 4 |
| Max Cores per CPU | 32 | 32 | 32 | 32 | 64 |
| Max RAM Capacity | 512 GB | 1 TB | 1 TB | 1 TB | 512 GB |
| Max Threads per CPU | 64 | 64 | 64 | 64 | 128 |
| Network Interface | 10GbE | 10GbE | 10GbE | 10GbE | 10GbE |
| Operating System | VMware ESXi | VMware ESXi | VMware ESXi | Windows Server | Windows Server |
| PCIe Slots | 4 | 4 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 800W | 1000W | 750W | 800W | 800W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 3rd Gen | Xeon 4th Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | P02465-B21 Enterprise Server | 767033-B21 Enterprise Rackmount Server | 776318-B21 | 810393-B21 | P19720-B21 |
| Product Type | Server | Server | Server | Server | Server |
| RAID Support | RAID 10 | RAID 10 | RAID 10 | RAID 10 | RAID 10 |
| RAM Slots | 8 | 8 | 16 | 16 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| Rail Kit Included | Yes | Yes | Yes | No | No |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 8 | 8 | 8 | 8 |
| Storage Type | SATA SSD | NVMe SSD | SATA HDD | NVMe SSD | SATA SSD |
| Use Case | Virtualization | Virtualization | Virtualization | Virtualization | Virtualization / File Server / Application Server |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 45 | 45 lbs | 45 lbs | 60 lbs | 45 lbs |
| Width | 19 | 19 inches | 17.3 inches | 17.5 inches | 17.2 inches |
Reviews & Ratings
S
Sohail Iftikhar
4
Excellent stability under heavy load.
D
Davide Conti
5
Consistent throughput for enterprise apps.
M
Marcus Dunn
3
Reliable power and cooling.
F
Furqan Aziz
4
Enterprise ready compute platform.
Questions & Answers
What are the key specifications of the HPE ProLiant DL380 Gen10 SKU P02465-B21?
The HPE ProLiant DL380 Gen10 SKU P02465-B21 includes dual Intel Xeon Silver 5218 processors (2.3 GHz, 16 cores each), 64 GB DDR4-R memory, HPE Smart Array P408i-a RAID controller, eight SFF drive bays, and an 800 W power supply.
How many processors and cores does the P02465-B21 server support?
This server supports two Intel Xeon Silver 5218 processors, delivering a total of 32 physical cores and 64 threads for high-performance computing.
What type and amount of memory is included in the P02465-B21?
The P02465-B21 ships with 64 GB of DDR4-Registered memory (4 x 16 GB RDIMMs) running at up to 2933 MT/s, expandable up to 3 TB using 24 DIMM slots.
What RAID controller is integrated into this server?
This model features the HPE Smart Array P408i-a SR Gen10 Controller, offering hardware RAID levels 0, 1, 5, 6, 10, 50, and 60 for enhanced data protection.