Servers HPE Proliant DL380 Gen10
Engineered to deliver unparalleled performance and reliability, the HPE Proliant DL380 Gen10 servers are ideal for mission-critical applications, advanced virtualization, and data-intensive workloads, optimizing operational efficiency.
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868703-B21 (HPE DL380 Gen10 8SFF CTO Server)
4.8 (5)- Server
- Rackmount
- 2U
- Intel
- Intel Xeon Scalable
- Xeon 3rd Gen
- Virtualization / File Server / Application Server
Est Value$2,478.54
$1,313.63
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824171-B21 (HPE OEM DL380 Gen9 24-SFF CTO Chassis)
4.2 (5)- Server
- Rackmount
- 2U
- Intel
- Intel Xeon Scalable
- Xeon 3rd Gen
- Virtualization
Est Value$2,335.90
$1,051.15
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719061-B21 (HPE DL380 Gen9 12LFF CTO Server)
4.2 (5)- Server
- Rackmount
- 2U
- Intel
- Intel Xeon Scalable
- Xeon 3rd Gen
- Virtualization / File Server / Application Server
Est Value$1,848.28
$1,127.45
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868706-B21 (HPE DL380 Gen10 8LFF CTO Server)
4.6 (5)- Server
- Rackmount
- 2U
- Intel
- Intel Xeon Scalable
- Xeon 3rd Gen
- Virtualization / File Server / Application Server
Est Value$2,336.91
$1,332.03
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810393-B21 (HPE DL380 G9 NVMe 6 SSD Exp Bay CTO Svr)
4.8 (5)- Server
- Rackmount
- 2U
- Intel
- Intel Xeon Scalable
- Xeon 3rd Gen
- Virtualization
Est Value$2,604.99
$1,563.00
40% offFirst-Time Buyer Discount – Get up to 2% additional off on your first order
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826564-B21 (HPE ProLiant DL380 Gen10 3106 1.7GHz 8-core 1P 16GB-R S100i 8SFF 500W PS Entry SATA Server)
4.6 (5)- Server
- Rackmount
- 2U
- Intel
- Intel Xeon Scalable
- Xeon 3rd Gen
- Virtualization / File Server / Application Server
Est Value$3,792.68
$1,592.92
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826681-B21 (HPE ProLiant DL380 Gen9 E5-2609v4 1.7GHz 8-core 1P 8GB-R B140i 8SFF 500W PS Entry SATA Server)
4.4 (5)- Server
- Rackmount
- 2U
- Intel
- Intel Xeon Scalable
- Xeon 3rd Gen
- Virtualization
Est Value$3,035.00
$1,782.00
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875759-S01 (HPE ProLiant DL380 Gen10 4112 2.6GHz 4-core 1P 16GB-R P408i-a 8LFF 1x500W PS Server/S-Buy)
4.4 (5)- Server
- Rackmount
- 2U
- Intel
- Intel Xeon Scalable
- Xeon 3rd Gen
- Virtualization
Est Value$2,730.44
$1,856.70
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867448-S01 (HPE ProLiant DL380 Gen9 E5-2620v4 2.1GHz 8-core 1P 16GB-R P440ar 8SFF 500W PS Server/S-Buy)
4.4 (5)- Server
- Rackmount
- 2U
- Intel
- Intel Xeon Scalable
- Xeon 3rd Gen
- Virtualization / File Server / Application Server
Est Value$2,224.61
$1,868.67
16% offFirst-Time Buyer Discount – Get up to 2% additional off on your first order
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868709-B21 (HPE ProLiant DL380 Gen10 3106 1.7GHz 8-core 1P 16GB-R S100i 8LFF 500W PS Entry SATA Server)
4.4 (5)- Server
- Rackmount
- 2U
- Intel
- Intel Xeon Scalable
- Xeon 3rd Gen
- Virtualization
Est Value$3,762.32
$2,106.89
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867450-S01 (HPE ProLiant DL380 Gen9 E5-2640v4 2.4GHz 10-core 1P 16GB-R P440ar 8SFF 500W PS Server/S-Buy)
5 (5)- Server
- Rackmount
- 2U
- Intel
- Intel Xeon Scalable
- Xeon 3rd Gen
- Virtualization
Est Value$2,629.27
$2,208.59
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826682-B21 (HPE ProLiant DL380 Gen9 E5-2620v4 2.1GHz 8-core 1P 16GB-R P440ar 8SFF 500W PS Base Server)
4.6 (5)- Server
- Rackmount
- 2U
- Intel
- Intel Xeon Scalable
- Xeon 4th Gen
- General Purpose
Est Value$3,939.00
$2,696.00
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859084-S01 (HPE ProLiant DL380 Gen9 E5-2620v4 2.1GHz 8-core 1P 16GB P440ar 24SFF 800W PS Server/S-Buy)
5 (5)- Server
- Rackmount
- 2U
- Intel
- Intel Xeon Scalable
- Xeon 3rd Gen
- Virtualization
Est Value$3,529.64
$2,964.90
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875763-S01 (HPE ProLiant DL380 Gen10 6126 2.6GHz 12-core 1P 32GB-R P408i-a 8SFF 2x500W PS Server/S-Buy)
4.2 (5)- Server
- Rackmount
- 2U
- Intel
- Intel Xeon Scalable
- Xeon 3rd Gen
- Virtualization / File Server / Application Server
Est Value$5,259.56
$3,418.71
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P02463-B21 (HPE ProLiant DL380 Gen10 4208 2.1GHz 8-core 1P 16GB-R S100i 12LFF 500W PS Server)
4.6 (5)- Server
- Rackmount
- 2U
- Intel
- Intel Xeon Scalable
- Xeon 4th Gen
- Virtualization / File Server / Application Server
Est Value$3,550.89
$3,479.87
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826565-B21 (HPE ProLiant DL380 Gen10 4114 2.2GHz 10-core 1P 32GB-R P408i-a 8SFF 500W PS Base Server)
4.4 (5)- Server
- Rackmount
- 2U
- Intel
- Intel Xeon Scalable
- Xeon 3rd Gen
- Virtualization / File Server / Application Server
Est Value$5,563.06
$3,615.99
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848774-B21 (HPE ProLiant DL380 Gen9 E5-2620v4 2.2GHz 10-core 1P 16GB-R P440ar 8SFF 500W PS Base Server)
4.6 (5)- Server
- Rackmount
- 1U
- Intel
- Intel Xeon Scalable
- Xeon 3rd Gen
- Virtualization / File Server / Application Server
Est Value$4,289.00
$3,644.00
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826683-B21 (HPE Proliant Dl380 Gen9 E5-2620v4 2.1GHz 8-core E5-2620v4 2.1GHz 8-core 1P 16GB-R P840ar 12LFF 2x800w PS Base Server)
4.8 (5)- Server
- Rackmount
- 2U
- Intel
- Intel Xeon Scalable
- Xeon 3rd Gen
- Virtualization / File Server / Application Server
Est Value$4,759.00
$4,043.00
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868710-B21 (HPE ProLiant DL380 Gen10 4110 2.1GHz 8-core 1P 32GB-R P816i-a 12LFF 2x800W PS Base Server)
4.6 (5)- Server
- Rackmount
- 2U
- Intel
- Intel Xeon Scalable
- Xeon 3rd Gen
- Virtualization
Est Value$6,068.88
$4,066.15
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875762-S01 (HPE ProLiant DL380 Gen10 6132 2.6GHz 14-core 1P 32GB-R P408i-a 8SFF 2x500W PS Server/S-Buy)
4.8 (5)- Server
- Rackmount / Tower
- 2U
- Intel
- Intel Xeon Scalable
- Xeon 4th Gen
- Virtualization / File Server / Application Server
Est Value$4,854.90
$4,078.12
16% offFirst-Time Buyer Discount – Get up to 2% additional off on your first order
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Questions & Answers
What are the key specifications of the HPE ProLiant DL380 Gen10 server?
The HPE ProLiant DL380 Gen10 features dual Intel Xeon Scalable processors, up to 3 TB DDR4 SmartMemory, 12 LFF or 24 SFF drive bays, HPE Smart Array storage controllers, and HPE iLO 5 remote management.
Which Intel processors are supported by the DL380 Gen10?
The DL380 Gen10 supports Intel Xeon Scalable Processor family (Bronze, Silver, Gold, Platinum) with up to 28 cores per CPU for flexible performance tiers.
How much memory can the DL380 Gen10 server accommodate?
It supports up to 3 TB of DDR4 ECC SmartMemory across 24 DIMM slots, including HPE Persistent Memory options for enhanced in-memory workload performance.
What storage options are available on the DL380 Gen10?
Choose from 12 LFF or 24 SFF HDD/SSD bays, including SAS, SATA, NVMe SSDs, and HPE NVMe Mixed Use or Read Intensive drive kits for high I/O performance.
Does the DL380 Gen10 support NVMe SSDs?
Yes, the server offers factory-integrated or retrofittable NVMe drive cages supporting up to 20 NVMe SSDs for ultra-low latency storage.
What RAID controllers are supported by the DL380 Gen10?
The DL380 Gen10 supports HPE Smart Array controllers, including P408i-a, P408e-p, and the HPE Smart Storage Accelerator for software RAID acceleration.
How many PCIe expansion slots does the server have?
It provides up to eight PCIe Gen3 slots in a standard 2U chassis, supporting mezzanine cards and FlexibleLOM for I/O customization.
What network connectivity options does the DL380 Gen10 offer?
Standard FlexibleLOM offers two 1/10 GbE ports; optional FlexibleLOM adapters support 25/50/100 GbE, and additional NICs can be added via PCIe slots.
Can I install GPUs in the HPE ProLiant DL380 Gen10?
Yes, the server supports up to three single-width or two double-width GPUs for AI, HPC, and VDI workloads, depending on cooling and power configurations.
What server management tools come with the DL380 Gen10?
HPE iLO 5 provides automated provisioning, remote management, firmware updates, health monitoring, and advanced security with silicon root of trust.
What security features does the DL380 Gen10 include?
It features HPE Silicon Root of Trust, Secure Boot, Secure Firmware Update, TPM 2.0, runtime firmware validation, and BIOS-level lockdown to prevent tampering.
Is the DL380 Gen10 energy efficient?
Yes, it uses HPE Power Discovery Services, multi-fan variable speed controls, and efficient power supplies (up to 94% platinum) to optimize energy usage.
What are common use cases for the DL380 Gen10?
Ideal for virtualization, database analytics, cloud, AI/ML inference, ERP, VDI, and high-performance computing requiring balanced compute, memory, and storage.
Does the DL380 Gen10 support virtualization platforms?
Yes, it is validated for VMware vSphere, Microsoft Hyper-V, Red Hat Virtualization, and Nutanix AHV, with optimized performance for virtual workloads.
What warranty and support options are available?
Standard warranty is 3-year parts, labor, and on-site support; HPE Foundation Care and Proactive Care Upgrades offer extended coverage, rapid response, and 24×7 support.
How do I configure RAID on the DL380 Gen10?
Use the HPE Smart Storage Administrator (SSA) in iLO or server BIOS to create and manage RAID levels (0, 1, 5, 6, 10, 50, 60) on the Smart Array controller.