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12LFF layout suits storage heavy environments.
P19718-B21
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HPE DL380 Gen10 12LFF NC CTO Svr
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P19718-B21
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- HPE DL380 Gen10 12LFF NC CTO Svr
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P19718-B21 Overview
P19718-B21 is a robust rackmount server engineered for enterprise environments, featuring support for Intel Xeon Scalable processors on an LGA 4189 socket and offering dual-processor (2P) scalability. It is designed with ECC DDR4 memory, supporting up to 1 TB via 16 memory slots, and includes expansion capabilities with 4 PCIe slots operating at PCIe 4.0.
P19718-B21 also provides versatile storage options with 8 drive bays supporting mixed 2.5-inch/3.5-inch configurations and RAID 10 support, alongside dual 10GbE network interfaces. With redundant 1200W power supplies, active cooling, integrated iDRAC for remote management, and native support for VMware ESXi, this server is ideally suited for data centers, virtualization, file serving, and application hosting.
P19718-B21 price is is available on request. Get immediate quote.
Request bulk order quote for P19718-B21 for additional pricing. Browse the full Hpe Proliant Dl380 Gen10 Servers series or explore all Hpe products.
P19718-B21 Specifications
- Product Type
- Server
- Form Factor
- Rackmount
- Rack Units
- 2U
- Processor Brand
- Intel
- Processor Series
- Intel Xeon Scalable
- Processor Generation
- Xeon 4th Gen
- Use Case
- Virtualization
- CPU Socket
- LGA 4189
- Scalability
- 2P
- Max Cores per CPU
- 32
- Max Threads per CPU
- 64
- RAM Type
- ECC DDR4
- RAM Slots
- 16
- Max RAM Capacity
- 1 TB
- Storage Type
- SATA SSD
- Storage Bays
- 8
- Drive Bay Size
- Mixed
- Hot-Swap Support
- Yes
- RAID Support
- RAID 10
- PCIe Slots
- 4
- PCIe Version
- PCIe 4.0
- Network Interface
- 10GbE
- LAN Ports
- 2
- Remote Management
- iDRAC
- Power Supply
- Redundant
- Power Supply Wattage
- 1200W
- Cooling
- Active
- Operating System
- VMware ESXi
- Virtualization Ready
- Yes
- GPU Support
- Yes
- Rail Kit Included
- Yes
- Product Name
- P19718-B21 Enterprise Server
- Height
- 3.5 inches
- Width
- 17.2 inches
- Depth
- 28 inches
- Weight
- 45 lbs
P19718-B21 Use Case
Enterprise Virtualization Consolidation with P19718-B21 HPE DL380 Gen10 12LFF CTO Server
A global finance firm deploys the P19718-B21 HPE DL380 Gen10 12LFF NC CTO Server to consolidate 200+ VMware ESXi instances onto two chassis. By leveraging dual Intel® Xeon® Scalable processors and 384 GB of DDR4 memory, the IT team achieves 30% higher VM density, a 25% reduction in rack footprint, and 20% lower power and cooling costs—delivering a scalable, resilient virtualization platform with industry-leading performance and efficiency.
High-Performance SQL Database & Analytics on HPE DL380 Gen10 P19718-B21
A retail analytics provider implements the P19718-B21 HPE DL380 Gen10 12LFF NC CTO Server as the primary on-premises SQL Server and Hadoop analytics node. Utilizing twelve 10 TB LFF SAS drives in RAID-10 and optional NVMe for log acceleration, the platform delivers sub-millisecond I/O latency and 3× faster query performance. This configuration ensures real-time reporting, meets SLA targets for data ingestion, and reduces TCO by consolidating disparate database and analytics engines onto a single, fault-tolerant server.
Hyperconverged Edge Infrastructure for Branch Offices with HPE DL380 Gen10 P19718-B21
A multinational retail chain standardizes its 500 branch locations on the P19718-B21 HPE DL380 Gen10 12LFF NC CTO Server as a VMware vSAN edge node. Each server supports up to 12 TB of hot-swappable storage, enabling local POS transaction processing, video surveillance recording, and cache acceleration. The solution delivers 99.99% uptime, simplifies centralized management via HPE OneView, and reduces WAN bandwidth consumption by 40%—ensuring uninterrupted customer service and rapid disaster recovery across distributed sites.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table 
| P19718-B21 |  827007-AA1 |  766342-B21 |  P02468-B21 |  850517-S01 | |
|---|---|---|---|---|---|
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Cooling | Active | Active | Active | Active | Active |
| Depth | 28 inches | 28 inches | 28.0 inches | 28 inches | 28 inches |
| Drive Bay Size | Mixed | 3.5-inch | Mixed | 2.5-inch | 2.5-inch |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | Yes | Yes | Yes | Yes | Yes |
| Height | 3.5 inches | 3.5 inches | 3.5 inches | 3.5 inches | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 2 | 4 | 2 | 2 | 2 |
| Max Cores per CPU | 32 | 32 | 32 | 32 | 32 |
| Max RAM Capacity | 1 TB | 1 TB | 2 TB | 1 TB | 512 GB |
| Max Threads per CPU | 64 | 64 | 64 | 64 | 64 |
| Network Interface | 10GbE | 10GbE | 10GbE | 10GbE | 10GbE |
| Operating System | VMware ESXi | Windows Server | Windows Server | Windows Server | VMware ESXi |
| PCIe Slots | 4 | 4 | 6 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 1200W | 1200W | 800W | 1200W | 750W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 4th Gen | Xeon 3rd Gen | Xeon 4th Gen | Xeon 3rd Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | P19718-B21 Enterprise Server | 827007-AA1 High-Performance Rackmount Server | 766342-B21 Enterprise Rackmount Server | ProX P02468-B21 Enterprise Server | 850517-S01 Official Rackmount Server |
| Product Type | Server | Server | Server | Server | Server |
| RAID Support | RAID 10 | RAID 0/1/5/10 | RAID 10 | RAID 10 | RAID 10 |
| RAM Slots | 16 | 16 | 16 | 16 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| Rail Kit Included | Yes | No | Yes | Yes | Yes |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 8 | 12 | 8 | 8 |
| Storage Type | SATA SSD | SATA HDD | Hybrid | NVMe SSD | SATA SSD |
| Use Case | Virtualization | Virtualization | Virtualization | Virtualization | Virtualization |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 45 lbs | 50 lbs | 50 lbs | 50 lbs | 45 lbs |
| Width | 17.2 inches | 17.2 inches | 17.5 inches | 17.2 inches | 17 inches |
Reviews & Ratings
A
Adil Raza
5
Stable chassis for large capacity deployments.
H
Hugo Martinez
4
Good cooling even with full drive population.
S
Sean Whitmore
5
Predictable performance once configured.
I
Irfan Saleem
5
Strong option for storage focused builds.
Questions & Answers
What does the HPE DL380 Gen10 12LFF NC CTO Server include out of the box?
The HPE DL380 Gen10 12LFF NC CTO Server ships as a bare-bones chassis with 12 large form-factor drive bays, tool-less rail kit, two hot-plug power supplies, and a system board preconfigured for customer-order customization.
Which processors can I install in the HPE DL380 Gen10 12LFF NC CTO Server?
This server supports dual Intel Xeon Scalable processors (up to Platinum series) for up to 28 cores per socket, delivering enterprise-class performance and workload acceleration.
How much memory does the HPE DL380 Gen10 12LFF NC CTO Server support?
With 24 DDR4 DIMM slots, the server supports up to 3 TB of memory using HPE SmartMemory, enabling fast in-memory analytics and virtualization density.
What storage options are available in the 12LFF chassis?
The 12LFF chassis accommodates up to 12 large form-factor SAS/SATA drives or optional NVMe drives, delivering flexible capacity and performance for database and backup applications.
Does the HPE DL380 Gen10 12LFF NC CTO Server include network adapters?
As a CTO (“NC” configuration), it ships without preinstalled network interface cards, allowing you to select from HPE FlexFabric, FlexLOM, or stand-up 1/10/25/40/100 GbE adapters.
Which operating systems are certified for this server?
HPE DL380 Gen10 is certified for Windows Server, VMware vSphere, Red Hat Enterprise Linux, SUSE Linux Enterprise Server, and other leading enterprise OS platforms.
How can I manage and monitor the HPE DL380 Gen10 Server?
Integrated HPE iLO 5 provides agentless remote management, firmware updates, and health monitoring through a secure web interface or HPE OneView integration.
What power supply options are supported?
The server supports redundant hot-plug HPE Flex Slot power supplies (500 W, 800 W, or 1600 W), offering high efficiency (>94% Platinum level) and Active Power Factor Correction.
Can I install this server in standard racks?
Yes, the HPE DL380 Gen10 is a 2U rack server with included tool-less sliding rails, compatible with 4-post racks and cabinets up to 24 inches deep.
What are the primary use cases for the DL380 Gen10 12LFF NC CTO?
Ideal for virtualization, database, high-performance computing, and file-sharing workloads, this server balances storage capacity, compute power, and I/O flexibility.
How does the server enhance data security?
HPE iLO 5 includes Silicon Root of Trust, secure recovery, and TPM 2.0 support, ensuring firmware authenticity and protecting against unauthorized code execution.
What warranty and support options are available?
Standard warranty includes 3 years parts, labor, and on-site service; optional HPE Pointnext Tech Care delivers advanced hardware and software support packages.
Can I expand memory and storage after deployment?
Yes, the modular design supports adding up to 24 DDR4 DIMMs and additional SAS/SATA or NVMe drives without downtime using hot-plug capabilities.
Does this server support NVMe drives?
With optional NVMe drive carriers and HPE Smart Array controllers or Native NVMe, you can deploy up to 12 NVMe SSDs for ultra-low latency storage.
What GPU acceleration does the DL380 Gen10 support?
The server supports up to three full-height, full-length GPUs in the 2U chassis, including NVIDIA Tesla and AMD Instinct accelerators for AI and HPC workloads.
How energy efficient is the HPE DL380 Gen10 Server?
Featuring HPE Flexible Slot power supplies (>94% efficiency), advanced cooling, and power-capping controls, this server reduces energy consumption and operating costs.