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752688-B21
HPE ProLiant DL380 Gen9 E5-2620v3 16GB-R P840/4GB 12LFF 2x80...
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752688-B21 is a high-performance rackmount server engineered for demanding data center environments. Designed to support Intel Xeon Scalable processors on the LGA 4189 socket, this server delivers exceptional compute power with a 2P scalability configuration, enabling reliable performance for virtualization and heavy workload applications. It features ECC DDR4 memory with 24 available RAM slots and a maximum capacity of up to 1 TB, ensuring robust memory performance for critical applications.
752688-B21 offers versatile expansion with 4 PCIe 4.0 slots and 8 hot-swap 3.5-inch storage bays with RAID 10 support to guarantee data integrity and protection. Equipped with multiple 1GbE network interfaces across 4 LAN ports, a redundant 1000W power supply, active cooling, and integrated iDRAC remote management, it is optimized for use as a file server, application server, and virtualization platform with supported operating systems including VMware ESXi and Windows Server.
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A global professional services firm deploys the 752688-B21 HPE ProLiant DL380 Gen9 as a VMware vSphere ESXi node to consolidate 10 legacy rack servers into a single chassis. Equipped with dual Intel® Xeon® E5-2620v3 processors, 16 GB of RAM (expandable to 1.5 TB), and an HPE Smart Array P840 RAID controller with 4 GB write-back cache, this server delivers 2.3× higher VM density, 40% lower power consumption per VM, and enterprise-grade I/O performance. Outcome: reduced data-center footprint by 70%, cut licensing and maintenance costs by 50%, and improved SLA compliance through hardware redundancy and HPE Integrated Lights-Out remote management.
A mid-market financial services company implements the 752688-B21 HPE ProLiant DL380 Gen9 to host its Microsoft SQL Server 2019 data warehouse. The server’s P840 controller with battery-backed write cache and 12LFF bays populated with SSDs accelerates OLAP query response times by 60%. Dual E5-2620v3 CPUs and scalable memory enable parallel processing of large financial datasets, while 2×800 W redundant power supplies ensure 99.99% uptime. Outcome: end-of-month financial close shortened from 48 hours to 8 hours, real-time BI dashboard refreshes in under 30 seconds, and guaranteed SLAs for 24×7 trading operations.
A multinational healthcare provider builds a Citrix Virtual Apps and Desktops environment on the 752688-B21 HPE ProLiant DL380 Gen9 to support secure remote access for 500 clinicians. The server’s Intel® Xeon® E5-2620v3 CPUs and 16 GB RAM (expandable to meet VDI demands) pair with HPE Persistent Memory and the P840 controller to minimize boot storms and application load times. HPE Sea of Sensors and redundant power supplies maintain HIPAA compliance through continuous hardware monitoring and fail-over. Outcome: clinicians experience sub-2-second login times, IT reduces VDI-related support tickets by 70%, and patient data security is enforced end-to-end.
To get the detailed certification, please go to the Compliance Center.
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4677 | LGA 4189 | LGA 4189 |
| Cooling | Active | Active | Active | Active | Active |
| Depth | 28.1 inches | 28 inches | 28 inches | 27.5 inches | 27 inches |
| Drive Bay Size | 3.5-inch | 2.5-inch | Mixed | 2.5-inch | Mixed |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | No | No | Yes | Yes | Yes |
| Height | 3.44 inches | 1.75 inches | 3.5 inches | 3.5 inches | 3 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 4 | 2 | 4 | 2 | 4 |
| Max Cores per CPU | 32 | 32 | 32 | 32 | 32 |
| Max RAM Capacity | 1 TB | 1 TB | 1 TB | 1 TB | 512 GB |
| Max Threads per CPU | 64 | 64 | 64 | 64 | 64 |
| Network Interface | 1GbE | 10GbE | 10GbE | 10GbE | 10GbE |
| Operating System | VMware ESXi | Windows Server / VMware ESXi / RHEL | VMware ESXi | VMware ESXi / Windows Server | Windows Server / VMware ESXi / RHEL |
| PCIe Slots | 4 | 4 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 1000W | 750W | 1000W | 1000W | 750W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 4th Gen | Xeon 3rd Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | 752688-B21 | 868709-AA1 Enterprise Rackmount Server | 827009-AA1 High Performance Rack Server | 875761-S01 Enterprise Server | 850519-S01 |
| Product Type | Server | Server | Server | Server | Server |
| RAID Support | RAID 10 | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 10 | RAID 10 | RAID 10 |
| RAM Slots | 24 | 16 | 16 | 16 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Rack Units | 2U | 1U | 2U | 2U | 2U |
| Rail Kit Included | N/A | Yes | Yes | Yes | N/A |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 8 | 8 | 8 | 8 |
| Storage Type | SATA SSD | NVMe SSD | Hybrid | NVMe SSD | Hybrid |
| Use Case | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server | Virtualization | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 75 lbs | 45 lbs | 60 lbs | 35 lbs | 55 lbs |
| Width | 17.3 inches | 19 inches | 19 inches | 17.5 inches | 17.5 inches |
12LFF configuration suits storage heavy environments.
Stable server for large capacity deployments.
Good cooling even with full drive population.
Predictable performance under load.
Reliable for storage focused roles.
The server offers Intel Xeon E5-2620v3 6-core processors, 16 GB DDR4 Registered RAM, HPE Smart Array P840/4 GB RAID, 12 LFF drive bays and dual 800 W redundant power supplies.
It includes one Intel Xeon E5-2620v3 six-core CPU clocked at 2.4 GHz with Turbo Boost up to 3.0 GHz and 15 MB Intel Smart Cache.
This server ships with 16 GB of DDR4 Registered memory across two DIMMs. You can upgrade up to 768 GB using 24 DIMM slots for maximum performance.
It features HPE Smart Array P840 with 4 GB cache and 12 front-access LFF bays. You can add up to 12 × 8 TB HDDs or SSDs for 96 TB total capacity.