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P06420-B21
HPE ProLiant DL380 Gen10 4110 2.1GHz 8-core 1P 16GB-R P408i-...
Federal agencies and Fortune 500 operations source through ORM Systems.
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Enterprise Clients
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Ten years serving buyers who audit their vendors. From federal agencies to 20,000+ enterprise clients worldwide.
P06420-B21 is a high-performance rackmount server engineered to support Intel Xeon Scalable processors of the 3rd Gen series with an LGA 4189 socket, enabling a dual-processor (2P) configuration that delivers robust computing power. It comes equipped with ECC DDR4 memory supporting up to 1 TB across 16 slots, along with 4 PCIe expansion slots and 8 hot-swap 2.5-inch storage bays featuring RAID 10 support and a 10GbE network interface with 2 LAN ports.
Optimized for demanding environments, this server includes redundant 1000W power supplies and active cooling to ensure reliable operation, complemented by integrated iDRAC remote management for streamlined maintenance. Its compatibility with operating systems such as Windows Server makes it an ideal solution for data center deployments, virtualization, file serving, and application server use cases.
P06420-B21 price is is available on request. Get immediate quote.
Request bulk order quote for P06420-B21 for additional pricing. Browse the full Hpe Proliant Dl380 Gen10 Servers series or explore all Hpe products.
A mid-sized enterprise implements the P06420-B21 HPE ProLiant DL380 Gen10 4110 2.1GHz 8-core Performance Server to consolidate 20+ VMware vSphere virtual machines for ERP, CRM and file services. Leveraging 16 GB RAM and the HPE P408i-a RAID controller with eight SFF bays, the deployment achieves 40% faster VM provisioning, 30% higher I/O throughput and 99.99% service availability—streamlining management, reducing rack footprint and cutting TCO.
A financial services firm uses the P06420-B21 HPE ProLiant DL380 Gen10 4110 8-core server to host mission-critical Microsoft SQL Server databases handling 10,000+ daily transactions. With optimized RAID-5 on the P408i-a controller and tiered flash storage, query latency drops by 25% while throughput scales 2× under peak load. The result is sub-second response times, improved customer experience and predictable transaction performance.
A global manufacturer deploys the P06420-B21 HPE ProLiant DL380 Gen10 4110 Performance Server at a smart-factory edge node to process real-time sensor data from 500+ machines. Equipped with 16 GB RAM and high-performance RAID, the server delivers sub-10 ms analytics, reduces WAN backhaul by 60% and supports predictive maintenance algorithms. The outcome is minimized downtime, lower bandwidth costs and rapid on-site decision-making.
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| P06420-B21 |  P02462-B21 |  P19719-B21 |  P06421-B21 |  826567-B21 | |
|---|---|---|---|---|---|
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Cooling | Active | Active | Active | Active | Active |
| Depth | 28.7 inches | 28.0 inches | 28.0 inches | 28 inches | 28.5 inches |
| Drive Bay Size | 2.5-inch | 2.5-inch | 3.5-inch | 3.5-inch | 3.5-inch |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | No | No | No | Yes | Yes |
| Height | 3.5 inches | 3.5 inches | 3.5 inches | 3.5 inches | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 2 | 4 | 4 | 2 | 4 |
| Max Cores per CPU | 16 | 32 | 32 | 32 | 32 |
| Max RAM Capacity | 1 TB | 1 TB | 512 GB | 2 TB | 512 GB |
| Max Threads per CPU | 32 | 64 | 64 | 64 | 64 |
| Network Interface | 10GbE | 10GbE | 10GbE | 10GbE | 10GbE |
| Operating System | Windows Server | Windows Server | Windows Server | Windows Server / VMware ESXi / Ubuntu | VMware ESXi |
| PCIe Slots | 4 | 4 | 4 | 6 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 1000W | 750W | 1200W | 1000W | 1000W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 4th Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | P06420-B21 | P02462-B21 Enterprise Rack Server | P19719-B21 Enterprise Rackmount Server | P06421-B21 | 826567-B21 Server |
| Product Type | Server | Server | Server | Server | Server |
| RAID Support | RAID 10 | RAID 5 | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 0 / RAID 1 / RAID 5 / RAID 6 / RAID 10 | RAID 10 |
| RAM Slots | 16 | 16 | 16 | 16 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR5 | ECC DDR4 |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 12 | 8 | 8 | 8 |
| Storage Type | NVMe SSD | SATA SSD | SAS HDD | SATA SSD | SATA SSD |
| Use Case | Application Server | Virtualization / File Server / Application Server | Virtualization | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 60 lbs | 45 lbs | 40 lbs | 45 lbs | 45 lbs |
| Width | 17.3 inches | 17.5 inches | 17.5 inches | 17.5 inches | 17.5 inches |
Every unit is authentic, sourced through trusted and authorised channels, and serial-verified on request. Genuine networking and IT hardware, guaranteed, or your money back.
New products are backed by up to 3 years of extended warranty, and certified refurbished units by up to 3 months, for dependable protection on every order. Coverage is clear, honoured in full, and confirmed on each product page.
If a unit ever falls short, our streamlined RMA process gets a replacement to you fast, with advance replacement available to keep your network running. No jargon, no runaround.
Every device is inspected, bench-tested, and firmware-verified, with configurations wiped before dispatch. Additional testing can be arranged to confirm full working condition on request.
Our specialists assist with compatibility, configuration, licensing, and installation, before and after you buy. Real hardware expertise, whenever you need it.
dispatched quickly and shipped worldwide from regional hubs, fully tracked and insured.
Performance oriented Gen10 server handles demanding tasks well.
Stable under continuous compute load.
Good balance of power and efficiency.
Reliable rack server for enterprise use.
Consistent production performance.
The server features an Intel Xeon Silver 4110 2.1GHz 8-core CPU, 16GB DDR4 RAM, HPE Smart Array P408i-a RAID controller, eight SFF drive bays and a 500W redundant power supply.
It supports a single Intel Xeon Silver 4110 processor with 8 physical cores, enabling multi-threaded workloads and virtualization.
It ships with 16GB of DDR4 Registered Memory, expandable up to 3TB across 24 DIMM slots for high-density applications.
You can install up to eight small form factor SAS or SATA drives, supporting NVMe via optional risers for up to 24 drives.
Yes. It includes a 500W hot-plug, high-efficiency power supply with N+1 redundancy options for continuous uptime.
The Xeon Silver 4110 offers 8 cores, 16 threads, Turbo Boost to 3.0GHz and 11MB cache, delivering balanced compute for virtualization and database tasks.
Add HPE Flexible Smart Array controllers, NVMe drive risers or upgrade to larger SFF/SAS drives. Up to 24 small form factor drives are supported.
It includes HPE iLO 5 for remote management, HPE OneView integration, Active Health System and Intelligent Provisioning for simplified deployment.
Yes. The server fully supports HPE OneView, enabling API-driven automation, firmware management and firmware compliance.
It offers Silicon Root of Trust, secure boot, runtime firmware validation and TPM 2.0 to protect firmware and data integrity.
Supported OSes include Windows Server, Red Hat Enterprise Linux, SUSE Linux Enterprise Server and VMware ESXi.
Use cases include virtualization, database workloads, high-performance computing, cloud infrastructure and enterprise applications.
It meets 80 PLUS Platinum efficiency, reducing power consumption by up to 94% under typical loads.
Yes. It supports future CPU upgrades up to 28 cores per socket and memory upgrades up to 3TB using HPE DDR4 SmartMemory.
Standard HPE 3-year Parts, Labor and Onsite support is included, with options to extend to 5 years or add 24x7 coverage.
It offers redundant power supplies, hot-plug drives, Smart Array RAID, iLO remote management and HPE InfoSight predictive analytics.
United States
