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Flexible CTO platform for custom server builds.
P15535-B21
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HPE ProLiant DL325 Gen10 Plus 24SFF CTO Server
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P15535-B21
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- HPE ProLiant DL325 Gen10 Plus 24SFF CTO Server
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P15535-B21 Overview
P15535-B21 is a rackmount server featuring Intel Xeon Scalable processors on an LGA 4189 socket, designed for 2P (dual-processor) scalability. It supports ECC DDR4 memory up to 2 TB capacity, includes four PCIe 4.0 expansion slots, accommodates storage bays with mixed 2.5-inch and 3.5-inch drive support, and offers RAID 10 for enhanced data resiliency.
Engineered for demanding enterprise deployments, the server comes with 10GbE network interfaces, redundant 1200W power supplies, and active cooling to ensure optimal performance under heavy workloads. With integrated iDRAC remote management and certified VMware ESXi compatibility, P15535-B21 is an ideal solution for data center environments, virtualization, file serving, and application hosting.
P15535-B21 price is is available on request. Get immediate quote.
Request bulk order quote for P15535-B21 for additional pricing. Browse the full Hpe Proliant Dl325 Gen10 Plus Servers series or explore all Hpe products.
P15535-B21 Specifications
- Product Type
- Server
- Form Factor
- Rackmount
- Rack Units
- 2U
- Processor Brand
- Intel
- Processor Series
- Intel Xeon Scalable
- Processor Generation
- Xeon 3rd Gen
- Use Case
- Virtualization
- CPU Socket
- LGA 4189
- Scalability
- 2P
- Max Cores per CPU
- 32
- Max Threads per CPU
- 64
- RAM Type
- ECC DDR4
- RAM Slots
- 16
- Max RAM Capacity
- 2 TB
- Storage Type
- NVMe SSD
- Storage Bays
- 8
- Drive Bay Size
- Mixed
- Hot-Swap Support
- Yes
- RAID Support
- RAID 10
- PCIe Slots
- 4
- PCIe Version
- PCIe 4.0
- Network Interface
- 10GbE
- LAN Ports
- 4
- Remote Management
- iDRAC
- Power Supply
- Redundant
- Power Supply Wattage
- 1200W
- Cooling
- Active
- Operating System
- VMware ESXi
- Virtualization Ready
- Yes
- GPU Support
- Yes
- Rail Kit Included
- Yes
- Product Name
- P15535-B21 Enterprise Server
- Height
- 3.5 inches
- Width
- 17.2 inches
- Depth
- 28.0 inches
- Weight
- 75 lbs
P15535-B21 Use Case
High-Density Virtual Desktop Infrastructure (VDI) Consolidation with VMware Horizon
In large enterprises deploying VMware Horizon or Citrix Virtual Apps, the P15535-B21 HPE ProLiant DL325 Gen10 Plus 24SFF CTO Server leverages a single-socket AMD EPYC™ CPU and 24 NVMe bays to host 300+ virtual desktops per chassis. Outcome: 35% reduction in datacenter footprint and 30% lower TCO, while delivering consistent end-user performance and simplified IT management via HPE OneView.
Edge-to-Cloud Retail Analytics for Real-Time Inventory Management
Multi-site retailers implement microservices-based POS and inventory tracking at each storefront using the DL325 Gen10 Plus’s high-core count and NVMe caching to process transactions locally with sub-5 ms latency. Outcome: 15% improvement in on-shelf availability, centralized analytics in HPE GreenLake Cloud, and accelerated promotional decision-making.
AI/ML Inference Acceleration for Manufacturing Quality Control
Manufacturing plants deploy computer-vision pipelines on the DL325 Gen10 Plus 24SFF CTO server—utilizing up to 64 AMD EPYC cores and optional GPU cards—to run real-time TensorFlow and PyTorch inference on high-resolution images. Outcome: defect detection accuracy increased by 25%, production throughput boosted by 20%, and compliance with Industry 4.0 quality standards.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table 
| P15535-B21 |  P18608-B21 |  P18603-B21 |  P15735-B21 |  P18606-B21 | |
|---|---|---|---|---|---|
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Cooling | Active | Active | Active | Active | Active |
| Depth | 28.0 inches | 30 inches | 29 inches | 29 inches | 28 inches |
| Drive Bay Size | Mixed | 3.5-inch | Mixed | 3.5-inch | 3.5-inch |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | Yes | No | Yes | Yes | Yes |
| Height | 3.5 inches | 3.5 inches | 3.5 inches | 3.5 inches | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 4 | 4 | 2 | 2 | 4 |
| Max Cores per CPU | 32 | 32 | 32 | 32 | 32 |
| Max RAM Capacity | 2 TB | 1 TB | 2 TB | 2 TB | 2 TB |
| Max Threads per CPU | 64 | 64 | 64 | 64 | 64 |
| Network Interface | 10GbE | 1GbE | 10GbE | 10GbE | 1GbE |
| Operating System | VMware ESXi | Windows Server | VMware ESXi | VMware ESXi | VMware ESXi |
| PCIe Slots | 4 | 4 | 6 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 1200W | 750W | 1200W | 800W | 750W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 4th Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | P15535-B21 Enterprise Server | P18608-B21 Enterprise Rack Server | P18603-B21 High Performance Rackmount Server | P15735-B21 High Performance Rack Server | P18606-B21 High-Performance Rack Server |
| Product Type | Server | Server | Server | Server | Server |
| RAID Support | RAID 10 | RAID 0 / RAID 1 / RAID 10 | RAID 5 | RAID 5 | RAID 0 / RAID 1 / RAID 10 |
| RAM Slots | 16 | 16 | 16 | 16 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| Rail Kit Included | Yes | Yes | Yes | No | Yes |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 8 | 8 | 8 | 8 |
| Storage Type | NVMe SSD | SATA HDD | SATA SSD | SATA HDD | SATA HDD |
| Use Case | Virtualization | Virtualization / File Server / Application Server | Virtualization | Virtualization / File Server / Application Server | Virtualization |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 75 lbs | 45 lbs | 40 lbs | 60 lbs | 65 lbs |
| Width | 17.2 inches | 17 inches | 17.5 inches | 17.2 inches | 19 inches |
Reviews & Ratings
S
Shahbaz Ahmed
4
Easy to configure for specific needs.
A
Antti Lehtinen
5
Good base for tailored deployments.
K
Kevin Monroe
5
Reliable HPE platform.
J
Jorge Ramirez
5
Customization options worked well.
Questions & Answers
What is the HPE ProLiant DL325 Gen10 Plus 24SFF CTO Server?
The HPE ProLiant DL325 Gen10 Plus 24SFF CTO Server is a 1U, single-socket AMD EPYC™-based rack server with 24 small-form-factor drive bays, designed for high-density virtualization, database and cloud workloads.
Which processors does the DL325 Gen10 Plus 24SFF CTO Server support?
This server supports 2nd-generation AMD EPYC™ processors up to 64 cores per socket, delivering up to 2X memory bandwidth and robust multi-threaded performance.
What memory configurations are available for this server?
The DL325 Gen10 Plus offers 8 DDR4 DIMM slots, supporting up to 2 TB of 3200 MT/s TruDDR4 memory with optional HPE Persistent Memory for in-memory analytics.
How many drives can the DL325 Gen10 Plus 24SFF accommodate?
It accommodates up to 24 SFF (2.5-inch) SAS/SATA drives or NVMe SSDs, providing up to 184 TB of raw capacity in a single 1U chassis.
Does the server support NVMe storage?
Yes, the DL325 Gen10 Plus 24SFF CTO Server supports up to 24 NVMe/U.2 drives for ultra-low latency and high I/O performance.
Which RAID controllers are compatible with this model?
Compatible controllers include HPE Smart Array P408e-p, P816i-a SR Gen10, and Smart Storage S100i, offering hardware-accelerated RAID 0/1/5/6/10/50 for data protection.
What GPU accelerators can be installed?
You can install single-width and half-height PCIe GPUs such as NVIDIA T4 or AMD MI50 for AI inference, machine learning and HPC workloads.
How does HPE iLO 5 enhance server management?
HPE iLO 5 provides agentless remote management, automated lifecycle tools, secure firmware updates and AI-driven analytics for 24/7 monitoring.
What security features are built in?
Built-in security includes silicon root of trust, Secure Boot, Run Safe firmware validation, cryptographically signed updates and TPM 2.0 for data integrity.
Which operating systems are certified?
The server is certified for Microsoft Windows Server, Red Hat Enterprise Linux, SUSE Linux Enterprise Server, VMware vSphere, and Ubuntu LTS editions.
What power supply and redundancy options are available?
Options include hot-plug, redundant 800W or 1600W Flex Slot Platinum Plus power supplies with hotswap capability and high-efficiency up to 94%.
What are the server’s dimensions and weight?
The chassis measures 1.7 x 17.5 x 27.2 inches (H x W x D) and weighs approximately 35 lbs (empty), fitting standard 19-inch racks.
What is the typical power consumption?
Typical operating power ranges from 200W to 500W depending on CPU, memory and drive configuration, with peak efficiency at 50% load.
How does Gen10 Plus differ from Gen10?
Gen10 Plus adds support for 2nd-gen AMD EPYC CPUs, higher memory speeds, PCIe Gen4, enhanced thermal design and improved security features over Gen10.
What workloads is this server best suited for?
Ideal for virtualization, cloud infrastructure, database services, high-performance computing, AI inference and data analytics in dense environments.
What warranty and support options are available?
Standard warranty is 3 years with next-business-day parts replacement; optional HPE Foundation Care and Proactive Care services extend coverage and SLAs.