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P15735-B21
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- HPE ProLiant DL325 Gen10 Plus 24SFF NVMe U.3 CTO Server
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P15735-B21 Overview
P15735-B21 is a rackmount server engineered for high-performance computing, supporting Intel Xeon Scalable processors on an LGA 4189 socket in a scalable 2P configuration. It utilizes ECC DDR4 memory technology with up to 2 TB capacity and offers 4 PCIe 4.0 expansion slots for enhanced system connectivity.
P15735-B21 is equipped with 8 x 3.5-inch hot-swap storage bays featuring RAID 5 support, dual 10GbE network interfaces for robust connectivity, and a redundant 800W power supply. With active cooling and iDRAC remote management, it supports operating systems such as VMware ESXi, making it ideal for data center deployments, virtualization, file serving, and application serving.
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P15735-B21 Specifications
| Product Type | Server |
| Form Factor | Rackmount |
| Rack Units | 2U |
| Processor Brand | Intel |
| Processor Series | Intel Xeon Scalable |
| Processor Generation | Xeon 4th Gen |
| Use Case | Virtualization / File Server / Application Server |
| CPU Socket | LGA 4189 |
| Scalability | 2P |
| Max Cores Per CPU | 32 |
| Max Threads Per CPU | 64 |
| RAM Type | ECC DDR4 |
| RAM Slots | 16 |
| Max RAM Capacity | 2 TB |
| Storage Type | SATA HDD |
| Storage Bays | 8 |
| Drive Bay Size | 3.5-inch |
| Hot-Swap Support | Yes |
| RAID Support | RAID 5 |
| PCIe Slots | 4 |
| PCIe Version | PCIe 4.0 |
| Network Interface | 10GbE |
| LAN Ports | 2 |
| Remote Management | iDRAC |
| Power Supply | Redundant |
| Power Supply Wattage | 800W |
| Cooling | Active |
| Operating System | VMware ESXi |
| Virtualization Ready | Yes |
| GPU Support | Yes |
| Rail Kit Included | No |
| Product Name | P15735-B21 High Performance Rack Server |
| Height | 3.5 inches |
| Width | 17.2 inches |
| Depth | 29 inches |
| Weight | 60 lbs |
P15735-B21 Use Case
Enterprise Virtual Desktop Infrastructure Consolidation
In a large financial services firm, IT architects deploy the P15735-B21-HPE ProLiant DL325 Gen10 Plus 24SFF NVMe U.3 CTO Server to consolidate 1,000+ virtual desktops. Leveraging its single-socket AMD EPYC™ CPU and NVMe storage, the server delivers sub-millisecond I/O and 20% lower power consumption vs. dual-socket alternatives. Outcome: 40% reduction in rack footprint, 30% lower licensing costs, and consistent end-user performance under peak loads—enabling scalable, secure VDI with optimized TCO.
High-Throughput OLTP Database Acceleration
A retail chain implements the HPE ProLiant DL325 Gen10 Plus to accelerate its point-of-sale and inventory management database. With 24 U.3 NVMe drives in a 2U chassis and hardware-accelerated encryption, the server sustains 1M+ transactions per second and secures PCI-compliant data at rest. Outcome: 5× faster order processing, real-time stock visibility, and enhanced data protection—empowering the chain to scale holiday sales without performance bottlenecks.
Edge AI Inference and Real-Time Analytics
A telecommunications provider deploys the P15735-B21-HPE ProLiant DL325 Gen10 Plus at distributed edge sites to run containerized AI inference for network anomaly detection. The server’s 128GB DDR4 memory and NVMe U.3 drives enable sub-second model loading and 99.9% detection accuracy. Outcome: proactive fault identification, 25% fewer network outages, and localized data processing—reducing bandwidth costs while delivering real-time insights close to the customer.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table
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| Cooling | Active | Active | Active | Active | Active |
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Depth | 29 inches | 28.0 inches | 28 inches | 29 inches | 30 inches |
| Drive Bay Size | Mixed | 3.5-inch | 3.5-inch | 3.5-inch | 3.5-inch |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | Yes | Yes | Yes | Yes | No |
| Height | 3.5 inches | 3.5 inches | 3.5 inches | 3.5 inches | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 2 | 2 | 2 | 2 | 4 |
| Max Cores per CPU | 32 | 32 | 32 | 32 | 32 |
| Max RAM Capacity | 2 TB | 1 TB | 1 TB | 2 TB | 1 TB |
| Max Threads per CPU | 64 | 64 | 64 | 64 | 64 |
| Network Interface | 10GbE | 10GbE | 10GbE | 10GbE | 1GbE |
| Operating System | VMware ESXi | Windows Server / VMware ESXi / Ubuntu / RHEL / SUSE / CentOS | VMware ESXi | VMware ESXi | Windows Server |
| PCIe Slots | 6 | 4 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 1200W | 1600W | 1200W | 800W | 750W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 4th Gen | Xeon 4th Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | P18603-B21 High Performance Rackmount Server | P18604-B21 | P18605-B21 Server | P15735-B21 High Performance Rack Server | P18608-B21 Enterprise Rack Server |
| Product Type | Server | Server | Server | Server | Server |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| RAID Support | RAID 5 | RAID 5 | RAID 10 | RAID 5 | RAID 0 / RAID 1 / RAID 10 |
| Rail Kit Included | Yes | N/A | Yes | No | Yes |
| RAM Slots | 16 | 16 | 16 | 16 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 8 | 8 | 8 | 8 |
| Storage Type | SATA SSD | SATA HDD | SATA SSD | SATA HDD | SATA HDD |
| Use Case | Virtualization | Virtualization / File Server / Application Server | Virtualization | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 40 lbs | 60 lbs | 45 lbs | 60 lbs | 45 lbs |
| Width | 17.5 inches | 17.3 inches | 17.5 inches | 17.2 inches | 17 inches |
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Questions & Answers
Q
What processors does the HPE ProLiant DL325 Gen10 Plus support?
A
The DL325 Gen10 Plus supports single AMD EPYC™ 7002 or 7003 Series processors with up to 64 cores, delivering exceptional performance for data-intensive workloads.
Q
How much memory can I install in the DL325 Gen10 Plus server?
A
This server accommodates up to 16 DDR4 DIMM slots, supporting up to 2 TB of RDIMM/LRDIMM memory at speeds up to 3200 MT/s for maximum application responsiveness.
Q
What storage options are available in the 24SFF NVMe U.3 chassis?
A
The 24-bay SFF chassis natively supports NVMe U.3 drives, enabling up to 153.6 TB of ultra-low latency storage with hot-plug capability for high-performance databases and virtualization.
Q
Can the DL325 Gen10 Plus be customized through CTO?
A
Yes. The Configure-to-Order (CTO) program lets you tailor CPUs, memory, storage, network adapters and HPE Smart Array controllers to match your specific deployment requirements.
Q
Which network interface options are supported?
A
Choose from onboard FlexibleLOM adapters up to 25 GbE, plus additional PCIe slots for 10, 25 or 100 GbE cards to ensure high-throughput, low-latency connectivity.
Q
How does HPE iLO enhance server management?
A
HPE Integrated Lights-Out (iLO) provides secure remote management, automated firmware updates and real-time health monitoring, reducing downtime and IT operational costs.
Q
What built-in security features protect this server?
A
The DL325 Gen10 Plus includes Silicon Root of Trust, Secure Boot, Runtime Firmware Validation and TPM 2.0 to safeguard firmware and protect against cyber threats.
Q
What power supplies and efficiency ratings are available?
A
Choose from redundant 800 W or 1600 W HPE Flex Slot Platinum Plus power supplies with up to 94% efficiency to optimize energy use and reduce operating expenses.
Q
Which operating systems are certified on this server?
A
HPE certifies Windows Server, Red Hat Enterprise Linux, SUSE Linux Enterprise Server and VMware ESXi, ensuring stable platform support and full driver integration.
Q
How does this server optimize virtualization workloads?
A
With high-core AMD EPYC CPUs, large memory capacity and NVMe storage, the server accelerates VM density and I/O performance for VDI, private cloud and container environments.
Q
What are the physical dimensions and weight?
A
This 1U rack server measures 43.5 cm (W) × 73.5 cm (D) × 4.4 cm (H) and weighs approximately 14.5 kg fully configured, fitting standard data-center racks.
Q
What expansion capabilities are available?
A
It offers three PCIe 4.0 slots (one x16, two x8) for GPUs, high-speed NICs or HBA cards, plus two M.2 slots for system boot drives.
Q
What warranty and support options exist?
A
HPE includes a 3-year hardware warranty with 24×7 support. Upgrade to Proactive Care or Foundation Care for advanced diagnostics, on-site response and comprehensive coverage.
Q
How does NVMe U.3 storage improve application performance?
A
NVMe U.3 drives deliver up to 6× higher IOPS and 10× lower latency than SAS SSDs, accelerating database transactions, analytics and real-time processing.
Q
Is this server optimized for containerized environments?
A
Yes. Its single-socket architecture, large memory footprint and NVMe I/O are ideally suited for Kubernetes, Docker and cloud-native applications.
Q
What energy-saving features does the DL325 Gen10 Plus include?
A
Features such as HPE Sea of Sensors, adaptive power capping and advanced cooling design minimize energy consumption while maintaining peak performance.