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Solid Xeon Silver processor for everyday Gen10 workloads with stable performance and low power consumption.
866526-L21
HPE ML350 Gen10 4110 Xeon-S FIO
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866526-L21
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- HPE ML350 Gen10 4110 Xeon-S FIO
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866526-L21 Overview
866526-L21 is a high-performance processor designed for rigorous computing demands. It is an Intel processor from the Intel 13th Gen family featuring the advanced Raptor Lake architecture and a modern LGA 1700 socket. With 16 cores and 24 threads, this CPU achieves a base clock speed of 3.6 GHz and boosts up to 5.0 GHz, while utilizing 16 MB of L2 cache and 30 MB of L3 cache. Its 125W TDP ensures a balanced blend of power and efficiency.
This processor also integrates Intel UHD Graphics 770, operating at a graphics base frequency of 350 MHz and reaching up to 1100 MHz dynamically, making it suitable for both immersive gaming and creative workstation tasks. It supports high-speed memory through DDR4 & DDR5 across dual channels and features PCIe 5.0 connectivity alongside unlocked overclocking options. Overall, the 866526-L21 is built for desktops demanding top-tier performance in gaming, workstation, and general use environments.
866526-L21 price is is available on request. Get immediate quote.
Request bulk order quote for 866526-L21 for additional pricing. Browse the full Hpe Ml350 Server Processors series or explore all Hpe products.
866526-L21 Specifications
- Product Type
- Processors
- Brand
- Intel
- Series
- Intel Core
- Category
- Desktop
- Max Memory Support
- 128 GB
- Memory Type Support
- DDR4 & DDR5
- Generation
- Intel 13th Gen
- Architecture
- Raptor Lake
- ECC Support
- No
- Security Features
- SGX
- CPU Socket
- LGA 1700
- Instruction Set Extensions
- AVX2
- Virtualization Support
- Intel VT-x
- Cores
- 16
- Threads
- 24
- Base Clock
- 3.6
- Max Boost Clock
- 5.0
- Overclocking Support
- Yes
- L2 Cache
- 16
- L3 Cache
- 30
- TDP
- 125W
- Integrated Graphics
- Intel UHD Graphics 770
- Graphics Base Frequency
- 350
- Graphics Max Dynamic Frequency
- 1100
- Memory Channels
- Dual
- PCIe Version
- PCIe 5.0
- Unlocked
- Yes
- Cooler Included
- No
- Use Case
- Gaming
- Product Name
- Intel Core i7-13700K
- Height
- 0.25
- Width
- 1.5
- Depth
- 1.5
- Weight
- 0.2
866526-L21 Use Case
High-Density Virtualization for SMB Infrastructure
In a mid-sized financial services firm running 50+ Windows and Linux virtual machines, the 866526-L21 HPE ML350 Gen10 with Intel Xeon-S 4110 drives consolidation and agility. Its eight-core processor, 192 GB DDR4 memory capacity and scalable NVMe storage enable 3:1 virtualization density. Benefit: 40 % reduction in rack footprint and 30 % lower power costs while maintaining enterprise-grade uptime for critical applications.
Real-Time Edge Analytics in Industrial IoT
A manufacturing plant leverages the 866526-L21 HPE ML350 Gen10 Xeon-S 4110 FIO at the production line edge to ingest and analyze sensor data from 500+ machines. With sub-millisecond I/O latency and hardware-accelerated security (TPM 2.0), it processes predictive maintenance algorithms locally. Benefit: 25 % fewer unplanned outages, 20 % increase in equipment utilization and compliance with industry 4.0 data integrity standards.
Secure On-Premises Backup and Disaster Recovery
A healthcare provider uses the 866526-L21 HPE ML350 Gen10 Xeon-S 4110 FIO as a local backup and DR node for electronic health record (EHR) systems. Configured with HPE StoreEasy storage and HPE iLO 5 remote management, it delivers automated daily snapshots and encrypted replication to an offsite vault. Benefit: 15-minute recovery point objective (RPO), sub-one-hour recovery time objective (RTO), and full HIPAA compliance.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table
 866526-L21 |  878660-L21 |  878659-L21 |  878657-L21 |  866538-L21 | |
|---|---|---|---|---|---|
| Product Type | Processors | Processors | Processors | Processors | Processors |
| Brand | Intel | Intel | Intel | Intel | Intel |
| Series | Intel Core | Intel Core | Intel Core | Intel Core | Intel Core |
| Category | Desktop | Desktop | Desktop | Desktop | Desktop |
| Max Memory Support | 128 GB | 128 GB | 128 GB | 128 GB | 128 GB |
| Memory Type Support | DDR4 & DDR5 | DDR4 & DDR5 | DDR5 | DDR5 | DDR4 & DDR5 |
| Generation | Intel 13th Gen | Intel 12th Gen | Intel 13th Gen | Intel 13th Gen | Intel 13th Gen |
| Architecture | Raptor Lake | Alder Lake | Raptor Lake | Raptor Lake | Raptor Lake |
| ECC Support | No | No | No | No | No |
| Security Features | SGX | SGX | None | None | None |
| CPU Socket | LGA 1700 | LGA 1700 | LGA 1700 | LGA 1700 | LGA 1700 |
| Instruction Set Extensions | AVX2 | AVX2 | AVX2 | AVX2 | AVX2 |
| Virtualization Support | Intel VT-x | Intel VT-x | Intel VT-x | Intel VT-x | Intel VT-x |
| Cores | 16 | 8 | 8 | 8 | 8 |
| Threads | 24 | 16 | 16 | 16 | 16 |
| Base Clock | 3.6 | 3.6 GHz | 3.6 | 3.6 | 3.2 GHz |
| Max Boost Clock | 5.0 | 4.9 GHz | 5.0 | 5.0 | 4.8 GHz |
| Overclocking Support | Yes | Yes | Yes | Yes | Yes |
| L2 Cache | 16 | 8 | 4 | 4 | 4 MB |
| L3 Cache | 30 | 16 | 16 | 24 | 16 MB |
| TDP | 125W | 125W | 125W | 125W | 125W |
| Integrated Graphics | Intel UHD Graphics 770 | Intel UHD Graphics 770 | Intel UHD Graphics 770 | Intel UHD Graphics 770 | Intel UHD Graphics 770 |
| Graphics Base Frequency | 350 | 300 MHz | 300 | 350 | 350 MHz |
| Graphics Max Dynamic Frequency | 1100 | 1100 MHz | 1150 | 1100 | 1200 MHz |
| Memory Channels | Dual | Dual | Dual | Dual | Dual |
| PCIe Version | PCIe 5.0 | PCIe 5.0 | PCIe 5.0 | PCIe 5.0 | PCIe 5.0 |
| Unlocked | Yes | Yes | Yes | Yes | Yes |
| Cooler Included | No | No | No | No | No |
| Use Case | Gaming | Gaming | Gaming | Gaming | Gaming |
| Product Name | Intel Core i7-13700K | Intel Core i7-12700K Processor | Intel Core i7-13700K | 878657-L21 | Intel Core i7-13700K |
| Height | 0.25 | N/A | 0.2 inches | 0.5 | N/A |
| Width | 1.5 | N/A | 1.48 inches | 0.5 | N/A |
| Depth | 1.5 | N/A | 1.48 inches | 0.5 | N/A |
| Weight | 0.2 | N/A | 0.3 lbs | 0.3 | N/A |
Reviews & Ratings
A
Arbaz Hussain
4
Runs reliably in production with no performance fluctuations.
S
Stefan Lindholm
5
Installed cleanly and recognized immediately by the system.
P
Paul Redding
3
Good fit for general purpose enterprise servers.
N
Naeem Siddiqui
4
Predictable and dependable CPU choice.
Questions & Answers
What are the key specifications of the HPE ML350 Gen10 4110 Xeon-S FIO (SKU: 866526-L21)?
The HPE ML350 Gen10 4110 Xeon-S FIO (866526-L21) features an Intel Xeon Silver 4110 CPU, up to 1.5 TB DDR4 memory, support for up to 24 SFF or 8 LFF drives, dual 10 GbE ports, HPE iLO 5 management, and redundant hot-plug PSUs.
Which Intel Xeon processor does the HPE ML350 Gen10 866526-L21 use?
The server is equipped with an Intel Xeon Silver 4110 processor, delivering 8 cores, 16 threads, a 2.1 GHz base frequency (up to 3.0 GHz Turbo), and 11 MB of L3 cache for balanced performance.
How much memory can the HPE ML350 Gen10 4110 Xeon-S FIO support?
This system supports up to 1.5 TB of DDR4 SmartMemory across 24 DIMM slots, enabling high-performance workloads and virtualization at enterprise scale.
What storage configurations are available on SKU 866526-L21?
You can configure the ML350 Gen10 with up to eight LFF or 24 SFF hot-plug SAS/SATA drives, plus optional NVMe drive support for high-throughput applications.