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Outstanding compute capacity for demanding enterprise workloads.
878665-B21
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HPE ML350 Gen10 8168 Xeon-P Kit
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878665-B21
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- HPE ML350 Gen10 8168 Xeon-P Kit
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878665-B21 Overview
878665-B21 is an AMD processor built on the Ryzen 5000 Series platform featuring the advanced Zen 3 architecture for high-performance desktop computing. With 8 cores and 16 threads, it delivers a base clock speed of 3.8 GHz and can boost up to 4.7 GHz. The chip includes 4 MB of L2 cache and 32 MB of L3 cache, operates with a thermal design power of 105W, and is designed for the AM4 socket platform. It supports DDR4 memory via dual channels and features a PCIe 4.0 interface, along with AMD-V virtualization and AVX2 instruction set extensions.
The unlocked multiplier allows for overclocking, making 878665-B21 well-suited for gaming and workstation environments where robust performance is key. Although it does not include integrated graphics, it pairs effectively with dedicated GPUs and compatible chipsets to meet the demands of high-end gaming, content creation, and general computing workloads.
878665-B21 price is is available on request. Get immediate quote.
Request bulk order quote for 878665-B21 for additional pricing. Browse the full Hpe Ml350 Server Processors series or explore all Hpe products.
878665-B21 Specifications
- Weight
- 0.20 lbs
- Depth
- 0.15 inches
- Width
- 1.48 inches
- ECC Support
- No
- Use Case
- Gaming
- Memory Channels
- Dual
- CPU Socket
- AM4
- PCIe Version
- PCIe 4.0
- Product Type
- Processors
- Integrated Graphics
- None
- Graphics Base Frequency
- N/A
- Graphics Max Dynamic Frequency
- N/A
- Cooler Included
- No
- Category
- Desktop
- Max Memory Support
- 128 GB
- Security Features
- None
- Instruction Set Extensions
- AVX2
- Cores
- 8
- Threads
- 16
- Overclocking Support
- Yes
- Unlocked
- Yes
- L2 Cache
- 4
- Memory Type Support
- DDR4
- Base Clock
- 3.8
- Height
- 1.48 inches
- Brand
- AMD
- Series
- AMD Ryzen
- Generation
- Ryzen 5000 Series
- Architecture
- Zen 3
- Virtualization Support
- AMD-V
- L3 Cache
- 32
- TDP
- 105W
- Max Boost Clock
- 4.7
- Product Name
- 878665-B21
878665-B21 Use Case
Virtualized Workload Consolidation in SMB Data Centers
In a mid-sized enterprise, IT teams deploy the 878665-B21 HPE ML350 Gen10 8168 Xeon-P Kit to consolidate over 50 Windows and Linux VMs onto a single 2U server. This configuration delivers 30% higher CPU utilization, reduces rack footprint by 2U, and cuts power consumption by 40%. Benefit: lowers total cost of ownership, streamlines management, and ensures performance headroom.
Edge AI Inference for Real-Time Retail Analytics
A regional retailer installs HPE ML350 Gen10 servers equipped with the 878665-B21 8168 Xeon-P Kit in stores to run on-premise computer vision analytics for customer traffic and inventory tracking. The optimized Xeon-P processors deliver sub-10ms inference latency, enabling dynamic pricing and personalized promotions. Benefit: enhances customer engagement and drives revenue growth.
Accelerated OLTP Database for Financial Services
A fintech company powers its real-time transaction platform with the 878665-B21 HPE ML350 Gen10 8168 Xeon-P Kit, handling 15,000 transactions per second with sub-millisecond response times via NVMe caching. Benefit: achieves 99.99% availability, meets regulatory compliance, and scales seamlessly during peak trading hours.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table 
| 878665-B21 |  866540-L21 |  878666-L21 |  878664-L21 |  801230-L21 | |
|---|---|---|---|---|---|
| Product Type | Processors | Processors | Processors | Processors | Processors |
| Brand | AMD | Intel | Intel | Intel | Intel |
| Series | AMD Ryzen | Intel Core | Intel Core | Intel Core | Intel Core |
| Category | Desktop | Desktop | Desktop | Desktop | Desktop |
| Max Memory Support | 128 GB | 128 GB | 128 GB | 128 GB | 128 GB |
| Memory Type Support | DDR4 | DDR4 & DDR5 | DDR5 | DDR4 & DDR5 | DDR5 |
| Generation | Ryzen 5000 Series | Intel 13th Gen | Intel 13th Gen | Intel 13th Gen | Intel 13th Gen |
| Architecture | Zen 3 | Raptor Lake | Raptor Lake | Raptor Lake | Raptor Lake |
| ECC Support | No | No | No | No | No |
| Security Features | None | SGX | None | None | SGX |
| CPU Socket | AM4 | LGA 1700 | LGA 1700 | LGA 1700 | LGA 1700 |
| Instruction Set Extensions | AVX2 | AVX-512 | AVX2 | AVX2 | AVX2 |
| Virtualization Support | AMD-V | Intel VT-x | Intel VT-x | Intel VT-x | Intel VT-x |
| Cores | 8 | 8 | 16 | 16 | 8 |
| Threads | 16 | 16 | 24 | 24 | 16 |
| Base Clock | 3.8 | 3.6 GHz | 3.2 GHz | 3.4 GHz | 3.6 |
| Max Boost Clock | 4.7 | 5.0 GHz | 5.0 GHz | 5.4 GHz | 5.0 |
| Overclocking Support | Yes | Yes | Yes | Yes | Yes |
| L2 Cache | 4 | 4 MB | 2 MB | 26 MB | 8 |
| L3 Cache | 32 | 16 MB | 24 MB | 30 MB | 24 |
| TDP | 105W | 95W | 125W | 125W | 125W |
| Integrated Graphics | None | Intel UHD Graphics 770 | Intel UHD Graphics 770 | Intel UHD Graphics 770 | Intel UHD Graphics 770 |
| Graphics Base Frequency | N/A | 350 MHz | N/A | 350 MHz | 300 |
| Graphics Max Dynamic Frequency | N/A | 1100 MHz | N/A | 1350 MHz | 1150 |
| Memory Channels | Dual | Dual | Dual | Dual | Dual |
| PCIe Version | PCIe 4.0 | PCIe 5.0 | PCIe 5.0 | PCIe 5.0 | PCIe 5.0 |
| Unlocked | Yes | Yes | Yes | Yes | Yes |
| Cooler Included | No | No | No | No | No |
| Use Case | Gaming | Gaming / Workstation / General Use | Gaming | Gaming | Gaming / Workstation |
| Product Name | 878665-B21 | Intel Core i7-866540-L21 | Intel Core i9-13 Series 878666-L21 | Intel Core i7-13700K Processor | 801230-L21 Processor |
| Height | 1.48 inches | 1.48 inches | 0.5 inches | 0.5 inches | 1.5 |
| Width | 1.48 inches | 1.48 inches | 0.5 inches | 1.5 inches | 1.5 |
| Depth | 0.15 inches | 0.17 inches | 0.125 inches | 1.5 inches | 1.5 |
| Weight | 0.20 lbs | 0.3 lbs | 0.2 lbs | 0.3 lbs | 0.75 |
Reviews & Ratings
S
Shoaib Akhtar
5
No stability issues during continuous high usage.
K
Kalle Niemi
5
Build quality and performance meet expectations.
J
Jonathan Reeves
4
Perfect fit for top tier ML350 Gen10 deployments.
A
Ahsan Mehmood
5
Delivers consistent high end performance.
Questions & Answers
What does the HPE ML350 Gen10 8168 Xeon-P Kit (SKU: 878665-B21) include?
The HPE 878665-B21 kit includes one Intel Xeon Platinum 8168 processor, an HPE-validated heat sink, thermal interface material and a CPU carrier tray, factory-integrated for immediate installation in an ML350 Gen10 server.
Is the Xeon-P 8168 Kit compatible with all HPE ProLiant ML350 Gen10 servers?
Yes. The 878665-B21 kit is fully compatible with HPE ProLiant ML350 Gen10 systems that use the LGA3647 socket and are running BIOS version 1.72 or later.
How many cores and threads does the Intel Xeon Platinum 8168 feature?
The Intel Xeon Platinum 8168 provides 24 cores and 48 threads, delivering high-density multi-threaded performance for virtualization, database and analytics workloads.
What are the base and maximum turbo frequencies of the Xeon Platinum 8168?
The CPU operates at a 2.7 GHz base frequency and can turbo boost up to 3.7 GHz under peak single-threaded workloads.
What is the thermal design power (TDP) for the Xeon-P 8168 Kit?
The Intel Xeon Platinum 8168 has a 155 W TDP, requiring the ML350 Gen10’s standard chassis cooling to maintain optimal operating temperatures.
Which memory types and capacities are supported by this kit?
The processor supports six-channel DDR4 memory at up to 2666 MT/s per channel, with a maximum capacity of 1.5 TB using Registered DIMMs or Intel Optane DC Persistent Memory modules.
Does the kit support Intel Optane DC Persistent Memory?
Yes. The Xeon Platinum 8168 Kit is validated for use with Intel Optane DC Persistent Memory, enabling larger in-memory databases and faster data recovery after power events.
What performance benefits does upgrading to the 8168 Xeon-P Kit deliver?
Upgrading boosts virtualization density by up to 30%, improves transaction throughput and adds hardware-accelerated encryption with Intel SGX and cryptographic extensions for enhanced security.
How do I install the HPE ML350 Gen10 8168 Xeon-P Kit?
Power down the server, open the chassis, seat the Xeon Platinum 8168 CPU in the LGA3647 socket, install the included heat sink per HPE’s installation guide and update the BIOS to the required version.
Do I need to update BIOS before installing this kit?
Yes. You must update your ML350 Gen10 server BIOS to version 1.72 or later to ensure full compatibility and stable operation with the Xeon Platinum 8168.
What warranty coverage comes with the 878665-B21 Kit?
HPE provides a standard three-year limited warranty on all factory-integrated components, with optional Foundation Care or Proactive Care service upgrades.
Can I mix this Xeon-P 8168 with other processor models in the same server?
No. HPE ProLiant servers require identical processor models in all populated CPU sockets; mixing different SKUs or microarchitectures is not supported.
How can I verify the authenticity of my HPE 878665-B21 Kit?
Check the HPE security label and serial number on the packaging, then validate against the HPE Genuine Parts Portal or through an authorized HPE reseller.
What cooling solution is required for the Xeon Platinum 8168 Kit?
The ML350 Gen10’s factory-configured air-cooling array is sufficient for the kit’s 155 W TDP; no additional fans or liquid cooling are necessary.
Where can I purchase the HPE ML350 Gen10 8168 Xeon-P Kit (878665-B21)?
Order directly from HPE or an authorized HPE channel partner. Provide SKU 878665-B21 to ensure you receive the genuine HPE kit.
What is HPE’s return policy for the 878665-B21 Kit?
HPE offers a 30-day return policy on unused, unopened kits. Contact your reseller or HPE support to obtain a return merchandise authorization (RMA).