Name:
P04646-B21
- Description:
- HPE ProLiant DL325 Gen10 7251 2.1GHz 8-core 1P 8GB-R E208i-a 4LFF 500W PS Entry Server
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3 Year Extended Warranty
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Smaller shipments go via DHL or FedEx Express — delivered worldwide in approximately 3 business days.
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Larger orders are dispatched through freight forwarding partners. Delivery takes 7–10 business days, globally.
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Free 14-Day Returns
Tested it, but it’s not a fit?
Return any product within 14 days of delivery if it doesn’t meet your technical or operational needs.
Initiate returns with ease.
Our RMA process is streamlined — just raise a request, follow the packaging guidelines, and we’ll handle the rest.
Refund or restock, your call.
Changed your mind? Get a refund (restocking fees may apply) or swap with another product.
30-Day Hardware Replacement
Covered for any early faults.
All equipment includes a 30-day replacement warranty. If something goes wrong, we’ll repair or swap it — fast.
Replacements shipped in 10 days or less.
Once your return is inspected and approved, we dispatch the replacement promptly to keep your operations moving.
RMA protocol keeps it smooth.
Just ensure all accessories and original packaging are intact — we’ll take care of the technical validation.
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P04646-B21 Overview
P04646-B21 is a high-performance rackmount server engineered for demanding data center and virtualization environments. It supports Intel Xeon Scalable processors on an LGA 4189 socket with a 2P scalability, enabling robust performance for enterprise applications. The server is built around ECC DDR4 memory technology with 16 memory slots supporting up to 1 TB of RAM, and it features 4 PCIe slots utilizing PCIe 4.0.
The P04646-B21 is designed with 8 hot-swap 3.5-inch drive bays for SAS HDD storage and supports RAID 0 / RAID 1 / RAID 5 / RAID 10 configurations, ensuring reliable data protection. It offers 4 x 10GbE network ports, redundant 750W power supplies, active cooling, and iDRAC for remote management. This server runs Windows Server, VMware ESXi, Ubuntu, and RHEL, making it an ideal choice for data centers, virtualization, file server, and application server deployments.
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P04646-B21 Specifications
| Product Type | Server |
| Form Factor | Rackmount |
| Rack Units | 2U |
| Processor Brand | Intel |
| Processor Series | Intel Xeon Scalable |
| Processor Generation | Xeon 3rd Gen |
| Use Case | Virtualization / File Server / Application Server |
| CPU Socket | LGA 4189 |
| Scalability | 2P |
| Max Cores Per CPU | 32 |
| Max Threads Per CPU | 64 |
| RAM Type | ECC DDR4 |
| RAM Slots | 16 |
| Max RAM Capacity | 1 TB |
| Storage Type | SAS HDD |
| Storage Bays | 8 |
| Drive Bay Size | 3.5-inch |
| Hot-Swap Support | Yes |
| RAID Support | RAID 0 / RAID 1 / RAID 5 / RAID 10 |
| PCIe Slots | 4 |
| PCIe Version | PCIe 4.0 |
| Network Interface | 10GbE |
| LAN Ports | 4 |
| Remote Management | iDRAC |
| Power Supply | Redundant |
| Power Supply Wattage | 750W |
| Cooling | Active |
| Operating System | Windows Server / VMware ESXi / Ubuntu / RHEL |
| Virtualization Ready | Yes |
| GPU Support | Yes |
| Rail Kit Included | Yes |
| Product Name | P04646-B21 High Performance Rack Server |
| Height | 3.44 inches |
| Width | 19 inches |
| Depth | 28 inches |
| Weight | 60 lbs |
P04646-B21 Use Case
Virtualization Consolidation for SMB Workloads
A mid-sized IT department deploys the P04646-B21-HPE ProLiant DL325 Gen10 7251 to consolidate 10 legacy servers into a single 8-core AMD EPYC node. This reduces datacenter rack space by 60%, lowers power consumption by 40%, and simplifies management via HPE OneView, delivering a 30% reduction in total cost of ownership.
High-Performance Database Hosting and Analytics
An e-commerce platform uses the P04646-B21-HPE ProLiant DL325 Gen10 7251 with 8GB memory to host MySQL and real-time analytics workloads. The server’s AMD EPYC 7251 cores and HPE Smart Array E208i-a enable sub-second query response and 3× higher transaction throughput, ensuring low-latency customer experiences and rapid inventory insights.
Edge Computing and Remote Site Reliability
A retail chain implements the P04646-B21-HPE ProLiant DL325 Gen10 7251 at 50 remote stores for local POS, IoT aggregation, and caching. Its compact 4LFF form factor, 500W power supply, and robust single-socket design deliver 99.99% uptime and under-5ms processing latency, optimizing bandwidth and ensuring seamless edge-site operations.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table
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| Cooling | Active | Active | Active | Active | Active |
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Depth | 28 inches | 28 inches | 28.2 inches | 28 inches | 28 |
| Drive Bay Size | Mixed | 3.5-inch | Mixed | 2.5-inch | 3.5-inch |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | No | Yes | Yes | No | No |
| Height | 3.5 inches | 3.44 inches | 3.5 inches | 3.5 inches | 3.5 |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 4 | 4 | 4 | 4 | 2 |
| Max Cores per CPU | 32 | 32 | 32 | 32 | 64 |
| Max RAM Capacity | 1 TB | 1 TB | 512 GB | 1 TB | 1 TB |
| Max Threads per CPU | 64 | 64 | 64 | 64 | 128 |
| Network Interface | 10GbE | 10GbE | 10GbE | 1GbE | 10GbE |
| Operating System | VMware ESXi | Windows Server / VMware ESXi / Ubuntu / RHEL | VMware ESXi | Windows Server / VMware ESXi / Ubuntu | VMware ESXi |
| PCIe Slots | 4 | 4 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 800W | 750W | 800W | 800W | 800W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 4th Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | P04648-B21 Enterprise Rack Server | P04646-B21 High Performance Rack Server | P04651-B21 Enterprise Server | P04654-B21 High Performance Rackmount Server | P04653-B21 |
| Product Type | Server | Server | Server | Server | Server |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| RAID Support | RAID 10 | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 10 | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 0, RAID 1, RAID 5, RAID 10 |
| Rail Kit Included | N/A | Yes | Yes | Yes | N/A |
| RAM Slots | 8 | 16 | 16 | 16 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 8 | 12 | 8 | 8 |
| Storage Type | SATA HDD | SAS HDD | Hybrid | SATA SSD | Hybrid |
| Use Case | Virtualization | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server | Virtualization |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 45 lbs | 60 lbs | 75 lbs | 45 lbs | 52 |
| Width | 17 inches | 19 inches | 17.3 inches | 17 inches | 17 |
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Questions & Answers
Q
What are the key specifications of the HPE ProLiant DL325 Gen10 7251 Entry Server (SKU: P04646-B21)?
A
The HPE ProLiant DL325 Gen10 features an AMD EPYC 7251 2.1 GHz 8-core CPU, 8 GB DDR4 RAM, HPE Smart Array E208i-a RAID controller, 4 LFF bays and a 500 W power supply.
Q
Which processor powers the HPE ProLiant DL325 Gen10 7251 server?
A
It is powered by an AMD EPYC 7251 processor clocked at 2.1 GHz with 8 cores and 16 threads, delivering enterprise-class performance and scalability.
Q
How much memory does the HPE ProLiant DL325 Gen10 include and is it expandable?
A
This server ships with 8 GB of DDR4 ECC Registered memory on a single module and supports up to 512 GB across eight DIMM slots.
Q
What storage configuration does the DL325 Gen10 support?
A
It offers four front-accessible 3.5″ bays for HDDs or SSDs, supporting up to 4 TB drives each, and features an integrated HPE Smart Array E208i-a RAID controller.
Q
Which RAID levels are supported by the HPE Smart Array E208i-a controller?
A
The E208i-a supports RAID 0, 1, 10 and 5, enabling data protection and performance optimization for mixed workload environments.
Q
What networking options come standard on the DL325 Gen10 server?
A
Standard networking includes two embedded 1 GbE ports. Additional 10 GbE or Fibre Channel adapters are available via two PCIe 3.0 slots.
Q
What power supply does the DL325 Gen10 use?
A
It includes a 500 W non-hot-plug, fixed unit optimized for entry workloads, delivering up to 92% efficiency under typical loads.
Q
What is the form factor of the HPE ProLiant DL325 Gen10 server?
A
This server is a 1U rack-mountable system, ideal for dense datacenter deployments requiring a compact footprint.
Q
Which operating systems are supported on the HPE ProLiant DL325 Gen10?
A
Supported OS options include VMware ESXi, Microsoft Windows Server, Red Hat Enterprise Linux, SUSE Linux Enterprise Server and Ubuntu.
Q
Is the DL325 Gen10 suitable for virtualization workloads?
A
Yes. With AMD EPYC multi-core performance, large memory capacity and HPE virtualization licenses, it supports VMware, Hyper-V and KVM environments.
Q
What security features are included in the DL325 Gen10 platform?
A
Built-in HPE Silicon Root of Trust, Secure Boot, Runtime Firmware Validation and Trusted Platform Module ensure firmware integrity and endpoint security.
Q
How many PCIe expansion slots are available?
A
The server provides two PCIe 3.0 slots (one x16 full-height, one x8 half-height) for network, storage or accelerator cards.
Q
What are the recommended use cases for the ProLiant DL325 Gen10?
A
Ideal for virtualization, databases, edge computing and general-purpose workloads requiring balanced CPU, memory and storage performance.
Q
What warranty coverage does the HPE ProLiant DL325 Gen10 include?
A
It comes with a standard 3-year HPE warranty featuring next business day exchange and 24×7 phone support.
Q
Can I upgrade the memory and storage on this server later?
A
Yes. Memory can be expanded up to 512 GB across eight DIMMs and storage can be upgraded by adding larger or additional drives in the 4 LFF bays.
Q
How do I order the HPE ProLiant DL325 Gen10 (P04646-B21)?
A
Contact an authorized HPE reseller or visit HPE’s online storefront. Provide SKU P04646-B21 for configuration and pricing details.