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P04646-B21
HPE ProLiant DL325 Gen10 7251 2.1GHz 8-core 1P 8GB-R E208i-a...
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P04646-B21 is a high-performance rackmount server engineered for demanding data center and virtualization environments. It supports Intel Xeon Scalable processors on an LGA 4189 socket with a 2P scalability, enabling robust performance for enterprise applications. The server is built around ECC DDR4 memory technology with 16 memory slots supporting up to 1 TB of RAM, and it features 4 PCIe slots utilizing PCIe 4.0.
The P04646-B21 is designed with 8 hot-swap 3.5-inch drive bays for SAS HDD storage and supports RAID 0 / RAID 1 / RAID 5 / RAID 10 configurations, ensuring reliable data protection. It offers 4 x 10GbE network ports, redundant 750W power supplies, active cooling, and iDRAC for remote management. This server runs Windows Server, VMware ESXi, Ubuntu, and RHEL, making it an ideal choice for data centers, virtualization, file server, and application server deployments.
P04646-B21 price is is available on request. Get immediate quote.
Request bulk order quote for P04646-B21 for additional pricing. Browse the full Hpe Proliant Dl325 Gen10 Servers series or explore all Hpe products.
A mid-sized IT department deploys the P04646-B21-HPE ProLiant DL325 Gen10 7251 to consolidate 10 legacy servers into a single 8-core AMD EPYC node. This reduces datacenter rack space by 60%, lowers power consumption by 40%, and simplifies management via HPE OneView, delivering a 30% reduction in total cost of ownership.
An e-commerce platform uses the P04646-B21-HPE ProLiant DL325 Gen10 7251 with 8GB memory to host MySQL and real-time analytics workloads. The server’s AMD EPYC 7251 cores and HPE Smart Array E208i-a enable sub-second query response and 3× higher transaction throughput, ensuring low-latency customer experiences and rapid inventory insights.
A retail chain implements the P04646-B21-HPE ProLiant DL325 Gen10 7251 at 50 remote stores for local POS, IoT aggregation, and caching. Its compact 4LFF form factor, 500W power supply, and robust single-socket design deliver 99.99% uptime and under-5ms processing latency, optimizing bandwidth and ensuring seamless edge-site operations.
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| P04646-B21 |  P04653-B21 |  P04648-B21 |  P04651-B21 |  P04654-B21 | |
|---|---|---|---|---|---|
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Cooling | Active | Active | Active | Active | Active |
| Depth | 28 inches | 28 | 28 inches | 28.2 inches | 28 inches |
| Drive Bay Size | 3.5-inch | 3.5-inch | Mixed | Mixed | 2.5-inch |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | Yes | No | No | Yes | No |
| Height | 3.44 inches | 3.5 | 3.5 inches | 3.5 inches | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 4 | 2 | 4 | 4 | 4 |
| Max Cores per CPU | 32 | 64 | 32 | 32 | 32 |
| Max RAM Capacity | 1 TB | 1 TB | 1 TB | 512 GB | 1 TB |
| Max Threads per CPU | 64 | 128 | 64 | 64 | 64 |
| Network Interface | 10GbE | 10GbE | 10GbE | 10GbE | 1GbE |
| Operating System | Windows Server / VMware ESXi / Ubuntu / RHEL | VMware ESXi | VMware ESXi | VMware ESXi | Windows Server / VMware ESXi / Ubuntu |
| PCIe Slots | 4 | 4 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 750W | 800W | 800W | 800W | 800W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 4th Gen | Xeon 3rd Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | P04646-B21 High Performance Rack Server | P04653-B21 | P04648-B21 Enterprise Rack Server | P04651-B21 Enterprise Server | P04654-B21 High Performance Rackmount Server |
| Product Type | Server | Server | Server | Server | Server |
| RAID Support | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 0, RAID 1, RAID 5, RAID 10 | RAID 10 | RAID 10 | RAID 0 / RAID 1 / RAID 5 / RAID 10 |
| RAM Slots | 16 | 16 | 8 | 16 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 8 | 8 | 12 | 8 |
| Storage Type | SAS HDD | Hybrid | SATA HDD | Hybrid | SATA SSD |
| Use Case | Virtualization / File Server / Application Server | Virtualization | Virtualization | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 60 lbs | 52 | 45 lbs | 75 lbs | 45 lbs |
| Width | 19 inches | 17 | 17 inches | 17.3 inches | 17 inches |
Every unit is authentic, sourced through trusted and authorised channels, and serial-verified on request. Genuine networking and IT hardware, guaranteed, or your money back.
New products are backed by up to 3 years of extended warranty, and certified refurbished units by up to 3 months, for dependable protection on every order. Coverage is clear, honoured in full, and confirmed on each product page.
If a unit ever falls short, our streamlined RMA process gets a replacement to you fast, with advance replacement available to keep your network running. No jargon, no runaround.
Every device is inspected, bench-tested, and firmware-verified, with configurations wiped before dispatch. Additional testing can be arranged to confirm full working condition on request.
Our specialists assist with compatibility, configuration, licensing, and installation, before and after you buy. Real hardware expertise, whenever you need it.
dispatched quickly and shipped worldwide from regional hubs, fully tracked and insured.
Entry DL325 performs reliably for light workloads.
Efficient server with low power usage.
Smooth deployment and stable performance.
Good value for AMD based infrastructure.
Meets expectations for entry deployments.
The HPE ProLiant DL325 Gen10 features an AMD EPYC 7251 2.1 GHz 8-core CPU, 8 GB DDR4 RAM, HPE Smart Array E208i-a RAID controller, 4 LFF bays and a 500 W power supply.
It is powered by an AMD EPYC 7251 processor clocked at 2.1 GHz with 8 cores and 16 threads, delivering enterprise-class performance and scalability.
This server ships with 8 GB of DDR4 ECC Registered memory on a single module and supports up to 512 GB across eight DIMM slots.
It offers four front-accessible 3.5″ bays for HDDs or SSDs, supporting up to 4 TB drives each, and features an integrated HPE Smart Array E208i-a RAID controller.
The E208i-a supports RAID 0, 1, 10 and 5, enabling data protection and performance optimization for mixed workload environments.
Standard networking includes two embedded 1 GbE ports. Additional 10 GbE or Fibre Channel adapters are available via two PCIe 3.0 slots.
It includes a 500 W non-hot-plug, fixed unit optimized for entry workloads, delivering up to 92% efficiency under typical loads.
This server is a 1U rack-mountable system, ideal for dense datacenter deployments requiring a compact footprint.
Supported OS options include VMware ESXi, Microsoft Windows Server, Red Hat Enterprise Linux, SUSE Linux Enterprise Server and Ubuntu.
Yes. With AMD EPYC multi-core performance, large memory capacity and HPE virtualization licenses, it supports VMware, Hyper-V and KVM environments.
Built-in HPE Silicon Root of Trust, Secure Boot, Runtime Firmware Validation and Trusted Platform Module ensure firmware integrity and endpoint security.
The server provides two PCIe 3.0 slots (one x16 full-height, one x8 half-height) for network, storage or accelerator cards.
Ideal for virtualization, databases, edge computing and general-purpose workloads requiring balanced CPU, memory and storage performance.
It comes with a standard 3-year HPE warranty featuring next business day exchange and 24×7 phone support.
Yes. Memory can be expanded up to 512 GB across eight DIMMs and storage can be upgraded by adding larger or additional drives in the 4 LFF bays.
Contact an authorized HPE reseller or visit HPE’s online storefront. Provide SKU P04646-B21 for configuration and pricing details.
United States
