United States$5,000,000+
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Victor Sanderson
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P408i controller performs well under IO load.
P04651-B21
HPE ProLiant DL325 Gen10 7351P 2.4GHz 16-core 1P 16GB-R P408...
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P04651-B21
- Description:
- HPE ProLiant DL325 Gen10 7351P 2.4GHz 16-core 1P 16GB-R P408i-a 8SFF 500W RPS Performance Server
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P04651-B21 Overview
P04651-B21 is a high-performance server offering a flexible form factor that can be deployed in both rackmount and tower configurations, tailored for modern data center environments and virtualization needs. It supports Intel Xeon Scalable processors (Xeon 3rd Gen) housed in an LGA 4189 socket and is scalable to a 2P configuration, ensuring robust processing power and efficiency. The system comes equipped with ECC DDR4 memory across 16 DIMM slots, supporting up to 512 GB, and provides multiple PCIe 4.0 expansion slots to accommodate various add-on cards.
Designed to be versatile, the P04651-B21 features a mixed drive bay design offering 12 storage bays suitable for both 2.5-inch and 3.5-inch drives with RAID 10 support for enhanced data protection. Integrated networking includes 10GbE with 4 LAN ports for fast connectivity, while redundant 800W power supplies and active cooling reinforce its reliability. Remote management is enabled via iDRAC, and the server is optimized for operating systems such as VMware ESXi, making it ideal for data center operations, virtualization, file serving, and application hosting.
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Request bulk order quote for P04651-B21 for additional pricing. Browse the full Hpe Proliant Dl325 Gen10 Servers series or explore all Hpe products.
P04651-B21 Specifications
- Product Type
- Server
- Form Factor
- Rackmount
- Rack Units
- 2U
- Processor Brand
- Intel
- Processor Series
- Intel Xeon Scalable
- Processor Generation
- Xeon 3rd Gen
- Use Case
- Virtualization / File Server / Application Server
- CPU Socket
- LGA 4189
- Scalability
- 2P
- Max Cores per CPU
- 32
- Max Threads per CPU
- 64
- RAM Type
- ECC DDR4
- RAM Slots
- 16
- Max RAM Capacity
- 512 GB
- Storage Type
- Hybrid
- Storage Bays
- 12
- Drive Bay Size
- Mixed
- Hot-Swap Support
- Yes
- RAID Support
- RAID 10
- PCIe Slots
- 4
- PCIe Version
- PCIe 4.0
- Network Interface
- 10GbE
- LAN Ports
- 4
- Remote Management
- iDRAC
- Power Supply
- Redundant
- Power Supply Wattage
- 800W
- Cooling
- Active
- Operating System
- VMware ESXi
- Virtualization Ready
- Yes
- GPU Support
- Yes
- Rail Kit Included
- Yes
- Product Name
- P04651-B21 Enterprise Server
- Height
- 3.5 inches
- Width
- 17.3 inches
- Depth
- 28.2 inches
- Weight
- 75 lbs
P04651-B21 Use Case
Virtualization Consolidation for SMB Remote Offices
In a multi‐location SMB environment, IT teams deploy the P04651-B21 HPE ProLiant DL325 Gen10 (7351P 2.4 GHz 16-core, 16 GB-R, P408i-a, 8 SFF, 500 W RPS) as a hypervisor host (VMware ESXi or Microsoft Hyper-V) to consolidate 20+ virtual machines per remote office. This single-socket, high-density server delivers enterprise-grade CPU performance and fast NVMe/SSD storage, reducing rack space, lowering power consumption by 30%, and cutting remote‐site IT management overhead by 40%.
High-Performance Transactional Database Hosting
An e-commerce enterprise runs mission-critical SQL Server and Oracle databases on the P04651-B21 HPE ProLiant DL325 Gen10 to achieve sub-5 ms I/O latency. The onboard P408i-a RAID controller with eight SFF drives enables high IOPS, while 16 GB of DDR4 memory scales to 1 TB for in-memory caching. Result: 2× faster transaction throughput, 99.99% availability, and simplified HA failover for peak sale events.
Secure Edge Analytics for Industrial IoT
A manufacturing plant deploys the P04651-B21 HPE ProLiant DL325 Gen10 as an edge compute node to process real-time sensor data in its SCADA network. With built-in silicon root of trust and TPM 2.0 security, the server ingests and analyzes 10,000+ data points per second locally, enabling predictive maintenance alerts within milliseconds. Outcome: 25% reduction in unplanned downtime and streamlined compliance reporting.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table
 P04651-B21 |  P04646-B21 |  P04648-AA1 |  P04654-B21 |  P04647-AA1 | |
|---|---|---|---|---|---|
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Cooling | Active | Active | Active | Active | Active |
| Depth | 28.2 inches | 28 inches | 28.74 inches | 28 inches | 28 inches |
| Drive Bay Size | Mixed | 3.5-inch | 3.5-inch | 2.5-inch | 2.5-inch |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | Yes | Yes | Yes | No | Yes |
| Height | 3.5 inches | 3.44 inches | 3.44 inches | 3.5 inches | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 4 | 4 | 2 | 4 | 4 |
| Max Cores per CPU | 32 | 32 | 32 | 32 | 32 |
| Max RAM Capacity | 512 GB | 1 TB | 1 TB | 1 TB | 1 TB |
| Max Threads per CPU | 64 | 64 | 64 | 64 | 64 |
| Network Interface | 10GbE | 10GbE | 10GbE | 1GbE | 10GbE |
| Operating System | VMware ESXi | Windows Server / VMware ESXi / Ubuntu / RHEL | Windows Server | Windows Server / VMware ESXi / Ubuntu | Windows Server |
| PCIe Slots | 4 | 4 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 800W | 750W | 800W | 800W | 750W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 4th Gen | Xeon 3rd Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | P04651-B21 Enterprise Server | P04646-B21 High Performance Rack Server | P04648-AA1 High Performance Rackmount Server | P04654-B21 High Performance Rackmount Server | P04647-AA1 High Performance Rack Server |
| Product Type | Server | Server | Server | Server | Server |
| RAID Support | RAID 10 | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 6 | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 5 |
| RAM Slots | 16 | 16 | 16 | 16 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| Rail Kit Included | Yes | Yes | Yes | Yes | Yes |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 12 | 8 | 8 | 8 | 8 |
| Storage Type | Hybrid | SAS HDD | SATA HDD | SATA SSD | SATA SSD |
| Use Case | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server | Virtualization |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 75 lbs | 60 lbs | 45 lbs | 45 lbs | 55 lbs |
| Width | 17.3 inches | 19 inches | 17.32 inches | 17 inches | 17.5 inches |
Reviews & Ratings
T
Tariq Bashir
4
Stable and responsive for enterprise tasks.
L
Laurent Chevalier
5
Good balance of compute and storage.
E
Edward Barnes
3
Reliable rack server for data centers.
S
Saif Qureshi
4
Strong performance and uptime.
Questions & Answers
What are the key specifications of the HPE ProLiant DL325 Gen10 7351P Performance Server?
The HPE ProLiant DL325 Gen10 7351P features a single AMD EPYC 7351P 2.4 GHz 16-core CPU, 16 GB RDIMM, HPE Smart Array P408i-a RAID, eight SFF drive bays and a 500 W RPS.
Which processor is installed in the HPE ProLiant DL325 Gen10 7351P?
This server is powered by a single AMD EPYC 7351P 2.4 GHz 16-core processor, delivering high per-core performance and scalability for enterprise workloads.
How much memory does the DL325 Gen10 support and ship with?
It ships with 16 GB DDR4 RDIMM and supports up to 2 TB of DDR4 RDIMM memory across 16 DIMM slots, enabling large-scale virtualization and data-intensive applications.
What storage options are available in the DL325 Gen10 8SFF chassis?
The DL325 Gen10 8SFF chassis supports up to eight hot-plug SFF SAS/SATA drives, NVMe boot options and external expansion via additional disk enclosures.