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P04649-B21
HPE ProLiant DL325 Gen10 7251 2.1GHz 8-core 1P 16GB-R P408i-...
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P04649-B21 is a high-performance rackmount server that supports Intel Xeon Scalable processors on an LGA 4189 socket, delivering 2P CPU scalability. It is designed with ECC DDR4 memory supporting up to 1 TB across 16 slots, features 4 PCIe 4.0 expansion slots, and includes 8 hot-swap 3.5-inch storage bays with comprehensive RAID 0/ RAID 1/ RAID 5/ RAID 10 support, along with a 10GbE network interface with 4 LAN ports.
This server offers a redundant 1000W power supply, active cooling, and integrated iDRAC remote management, making it ideal for data center deployments, virtualization platforms, file serving, and application hosting. It is fully compatible with operating systems such as Windows Server, VMware ESXi, and Ubuntu, ensuring versatile and reliable performance across a variety of enterprise use cases.
P04649-B21 price is is available on request. Get immediate quote.
Request bulk order quote for P04649-B21 for additional pricing. Browse the full Hpe Proliant Dl325 Gen10 Servers series or explore all Hpe products.
Scenario: A global enterprise consolidates 200 virtual desktops on a single 1U P04649-B21-HPE ProLiant DL325 Gen10 7251 2.1 GHz 8-core server. Leveraging 16 GB RAM, P408i-a RAID, and dual 500 W power supplies, IT delivers sub-5 ms latency for all users. Outcome: 35 % infrastructure cost savings, guaranteed high availability through redundant PSUs, and streamlined lifecycle management with HPE iLO.
Scenario: A smart-manufacturing plant deploys the P04649-B21-HPE ProLiant DL325 Gen10 7251 server at the edge to process live sensor streams and run predictive maintenance models. The AMD EPYC 8-core CPU, 16 GB RAM, and hardware RAID accelerate data ingestion and analytics. Outcome: 20 % reduction in unplanned downtime, sub-second anomaly detection, and secure data processing with HPE Silicon Root of Trust.
Scenario: A mid-market e-commerce company implements the P04649-B21-HPE ProLiant DL325 Gen10 7251 server as its primary on-prem database host for PCI-compliant transactions. Equipped with P408i-a RAID, hardware encryption, and dual 500 W PSUs, the system delivers 8 GB/s I/O throughput. Outcome: 99.99 % uptime, end-to-end data security, and a 40 % performance boost over legacy infrastructure.
To get the detailed certification, please go to the Compliance Center.
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Cooling | Active | Active | Active | Active | Active |
| Depth | 28 inches | 28 inches | 28 inches | 28 inches | 28 inches |
| Drive Bay Size | 3.5-inch | 2.5-inch | 2.5-inch | 3.5-inch | 2.5-inch |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | Yes | No | Yes | Yes | Yes |
| Height | 3.5 inches | 3.5 inches | 3.5 inches | 3.44 inches | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 4 | 4 | 4 | 4 | 2 |
| Max Cores per CPU | 32 | 32 | 32 | 32 | 32 |
| Max RAM Capacity | 1 TB | 1 TB | 1 TB | 1 TB | 1 TB |
| Max Threads per CPU | 64 | 64 | 64 | 64 | 64 |
| Network Interface | 10GbE | 1GbE | 10GbE | 10GbE | 10GbE |
| Operating System | Windows Server / VMware ESXi / Ubuntu | Windows Server / VMware ESXi / Ubuntu | Windows Server | Windows Server / VMware ESXi / Ubuntu / RHEL | Windows Server |
| PCIe Slots | 4 | 4 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 1000W | 800W | 750W | 750W | 1600W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 4th Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 4th Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | P04649-B21 High Performance Rack Server | P04654-B21 High Performance Rackmount Server | P04647-AA1 High Performance Rack Server | P04646-B21 High Performance Rack Server | P04646-AA1 |
| Product Type | Server | Server | Server | Server | Server |
| RAID Support | RAID 0/ RAID 1/ RAID 5/ RAID 10 | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 5 | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 1 / RAID 5 / RAID 10 |
| RAM Slots | 16 | 16 | 16 | 16 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| Rail Kit Included | Yes | Yes | Yes | Yes | N/A |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 8 | 8 | 8 | 8 |
| Storage Type | Hybrid | SATA SSD | SATA SSD | SAS HDD | SATA SSD |
| Use Case | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server | Virtualization | Virtualization / File Server / Application Server | Virtualization |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 50 lbs | 45 lbs | 55 lbs | 60 lbs | 45 lbs |
| Width | 17 inches | 17 inches | 17.5 inches | 19 inches | 17 inches |
Solution configuration works well for defined use cases.
Stable server with good storage performance.
Predictable behavior under continuous load.
Reliable for application hosting.
Solid enterprise solution.
The HPE ProLiant DL325 Gen10 (P04649-B21) features an AMD EPYC 7251 2.1 GHz 8-core processor, 16 GB DDR4 memory, an HPE Smart Array P408i-a RAID controller, eight SFF drive bays, and dual 500 W hot-plug power supplies.
It is powered by an AMD EPYC 7251 2.1 GHz single-socket 8-core processor, delivering robust per-core performance and energy efficiency for compute-intensive workloads.
This server ships with 16 GB of DDR4 ECC UDIMM memory in two slots and supports up to 512 GB across eight DIMM slots, enabling seamless scaling for virtualization and data-intensive applications.
It offers eight front-accessible SFF bays for SAS/SATA drives, supports NVMe drive cards, and includes the HPE Smart Array P408i-a RAID controller for hardware-accelerated RAID 0/1/5/6/10/50/60 configurations.