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DL380 Gen10 handles mixed workloads efficiently.
P05524-291
HPE ProLiant DL380 Gen10 4110 2.1GHz 8-core 1P 16GB-R P408i-...
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P05524-291
- Description:
- HPE ProLiant DL380 Gen10 4110 2.1GHz 8-core 1P 16GB-R P408i-a 8SFF 500W RPS Solution
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P05524-291 Overview
P05524-291 is a robust rackmount server engineered for demanding data center environments. It supports Intel Xeon Scalable processors on an LGA 4189 socket with 2P scalability, paired with ECC DDR4 memory supporting capacities up to 512 GB across 16 DIMM slots, ensuring high-performance computing for mission-critical workloads.
The server features 8 PCIe 4.0 expansion slots, dual hot-swappable 3.5-inch SATA SSD storage bays with RAID 0, RAID 1, and RAID 10 options, and an integrated 1GbE network interface. It is powered by redundant 750W power supplies with active cooling and managed remotely via iDRAC, while supporting operating systems such as Windows Server, VMware ESXi, Ubuntu, and RHEL, making it ideal for virtualization, file serving, and application hosting.
P05524-291 price is is available on request. Get immediate quote.
Request bulk order quote for P05524-291 for additional pricing. Browse the full Hpe Proliant Dl380 Gen10 Servers series or explore all Hpe products.
P05524-291 Specifications
- Product Type
- Server
- Form Factor
- Rackmount
- Rack Units
- 2U
- Processor Brand
- Intel
- Processor Series
- Intel Xeon Scalable
- Processor Generation
- Xeon 3rd Gen
- Use Case
- Virtualization
- CPU Socket
- LGA 4189
- Scalability
- 2P
- Max Cores per CPU
- 32
- Max Threads per CPU
- 64
- RAM Type
- ECC DDR4
- RAM Slots
- 16
- Max RAM Capacity
- 512 GB
- Storage Type
- SATA SSD
- Storage Bays
- 2
- Drive Bay Size
- 3.5-inch
- Hot-Swap Support
- Yes
- RAID Support
- RAID 0 / RAID 1 / RAID 10
- PCIe Slots
- 8
- PCIe Version
- PCIe 4.0
- Network Interface
- 1GbE
- LAN Ports
- 1
- Remote Management
- iDRAC
- Power Supply
- Redundant
- Power Supply Wattage
- 750W
- Cooling
- Active
- Operating System
- Windows Server / VMware ESXi / Ubuntu / RHEL
- Virtualization Ready
- Yes
- GPU Support
- No
- Rail Kit Included
- N/A
- Product Name
- P05524-291 High Performance Rack Server
- Height
- 3.5 inches
- Width
- 17.2 inches
- Depth
- 27.5 inches
- Weight
- 45 lbs
P05524-291 Use Case
Virtualization & Server Consolidation for Midsize Enterprises
A midsize manufacturing firm deploys the P05524-291 HPE ProLiant DL380 Gen10 (4110 2.1GHz 8-core, 16GB-R, P408i-a, 8SFF, 500W RPS) as a VMware ESXi host to consolidate ten aging servers into virtual machines. Leveraging HPE OneView and integrated iLO 5 management, IT reduces rack space by 70%, cuts power and cooling costs by 40%, and boosts overall resource utilization by 30%, delivering faster provisioning and simplified operations.
High-Performance Database & ERP Hosting for Financial Services
A regional bank implements the P05524-291 HPE ProLiant DL380 Gen10 (4110 2.1GHz 8-core, 16GB-R, P408i-a RAID, 8SFF, 500W RPS) to run its core banking database and ERP applications. With hardware-accelerated RAID, secure firmware validated by HPE Silicon Root of Trust, and redundant power supplies, the server achieves 99.99% uptime, accelerates transaction processing by 25%, and ensures compliance with data-at-rest encryption and audit trails.
Edge Computing & VDI Deployment for Retail Branch Offices
A national retail chain rolls out the P05524-291 HPE ProLiant DL380 Gen10 (4110 2.1GHz 8-core, 16GB-R, P408i-a, 8SFF, 500W RPS) at 200 branch locations to host Citrix Virtual Desktops and local file caching. Built-in redundancy with 500W RPS and eight hot-swap bays ensures 24/7 availability, while local compute offloads central WAN traffic by 35%, delivers sub-50ms login times, and simplifies patch management from a centralized HPE OneView console.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table
 P05524-291 |  875762-S01 |  P06423-B21 |  850517-S01 |  Q9A05A | |
|---|---|---|---|---|---|
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Cooling | Active | Active | Active | Active | Active |
| Depth | 27.5 inches | 28 inches | 28.7 inches | 28 inches | 28.7 inches |
| Drive Bay Size | 3.5-inch | Mixed | 3.5-inch | 2.5-inch | Mixed |
| Form Factor | Rackmount | Rackmount / Tower | Rackmount | Rackmount | Rackmount |
| GPU Support | No | Yes | Yes | Yes | Yes |
| Height | 3.5 inches | 3.5 inches | 3.5 inches | 3.5 inches | 3.44 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 1 | 4 | 4 | 2 | 2 |
| Max Cores per CPU | 32 | 32 | 32 | 32 | 32 |
| Max RAM Capacity | 512 GB | 512 GB | 2 TB | 512 GB | 1 TB |
| Max Threads per CPU | 64 | 64 | 64 | 64 | 64 |
| Network Interface | 1GbE | 10GbE | 10GbE | 10GbE | 10GbE |
| Operating System | Windows Server / VMware ESXi / Ubuntu / RHEL | Windows Server / VMware ESXi / Ubuntu | VMware ESXi | VMware ESXi | Windows Server / VMware ESXi / Ubuntu |
| PCIe Slots | 8 | 4 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 750W | 1000W | 1000W | 750W | 800W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 3rd Gen | Xeon 4th Gen | Xeon 4th Gen | Xeon 3rd Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | P05524-291 High Performance Rack Server | Server 875762-S01 | P06423-B21 Enterprise Rack Server | 850517-S01 Official Rackmount Server | Q9A05A Server |
| Product Type | Server | Server | Server | Server | Server |
| RAID Support | RAID 0 / RAID 1 / RAID 10 | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 5 | RAID 10 | RAID 10 |
| RAM Slots | 16 | 16 | 16 | 16 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| Rail Kit Included | N/A | No | Yes | Yes | No |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 2 | 8 | 8 | 8 | 8 |
| Storage Type | SATA SSD | Hybrid | NVMe SSD | SATA SSD | NVMe SSD |
| Use Case | Virtualization | Virtualization / File Server / Application Server | Virtualization | Virtualization | Virtualization / File Server / Application Server |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 45 lbs | 45 lbs | 45 lbs | 45 lbs | 45 lbs |
| Width | 17.2 inches | 17 inches | 17.3 inches | 17 inches | 17.2 inches |
Reviews & Ratings
E
Edward Livingston
4
Stable server with good expansion options.
J
Julian Ford
5
Reliable compute and storage balance.
M
Marcus Hinton
3
Smooth deployment and predictable performance.
P
Philip Grant
4
Enterprise grade reliability.
Questions & Answers
What processor does the HPE ProLiant DL380 Gen10 (SKU P05524-291) use?
The server is equipped with a single Intel Xeon Silver 4110 processor featuring 8 cores at 2.1 GHz.
How much memory is installed and supported in this system?
It ships with 16 GB of DDR4 RDIMM and supports up to 1.5 TB across 24 DIMM slots for future expansion.
What drive types and capacities can I install in the 8SFF backplane?
The 8-bay SFF backplane accepts hot-plug SAS, SATA and NVMe drives, enabling up to 64 TB of raw capacity with 8 × 8 TB drives.
Which RAID levels does the HPE Smart Array P408i-a controller support?
The integrated Smart Array P408i-a supports RAID 0, 1, 5, 6, 10, 50 and 60 for robust data protection.