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Scott Reynolds
4
480GB NVMe M.2 provided fast boot and app load times.
875579-B21
HPE 480GB NVMe x4 RI M.2 22110 DS SSD
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875579-B21
- Description:
- HPE 480GB NVMe x4 RI M.2 22110 DS SSD
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875579-B21 Overview
875579-B21 is a high-performance HDD engineered for enterprise usage, featuring a 3.5-inch form factor and a SATA III interface. It spins at 7200 RPM and offers a 4 TB storage capacity with a 128 MB cache, delivering reliable 24/7 operation with a workload rating of 180 TB/yr and an MTBF of 1,000,000 hours for data center and server environments.
875579-B21 is designed for use in desktops, servers, NAS systems, and surveillance applications. It boasts advanced features including helium-sealed construction, vibration protection, and dual actuator technology. With efficient power consumption ratings of 8.5 Watts (read/write) and 5.5 Watts (idle), this drive is built to meet the demands of modern data storage infrastructures.
875579-B21 price is is available on request. Get immediate quote.
Request bulk order quote for 875579-B21 for additional pricing. Browse the full Hpe Server M.2&Pcie Hard Drives series or explore all Hpe products.
875579-B21 Specifications
- Product Type
- Hard Drive
- Drive Type
- HDD
- Use Case
- Desktop / Server / NAS / Surveillance / Enterprise Storage
- Interface
- SATA III
- Form Factor
- 3.5-inch
- Storage Capacity
- 4 TB
- Spindle Speed (RPM)
- 7200 RPM
- Cache (Buffer Size)
- 128 MB
- Average Latency
- N/A
- Data Transfer Rate
- Up to 250 MB/s
- Annual Workload Rating
- 180 TB/yr
- Power Consumption (Read/Write)
- 8.5 Watts
- Power Consumption (Idle)
- 5.5 Watts
- Encryption Support
- AES 256-bit
- Helium Sealed
- Helium-Sealed
- Drive Bays Supported
- Multi-bay
- Vibration Protection
- Yes
- Advanced Features
- Dual Actuator
- Operating Temperature
- 5–60°C
- Product Name
- 875579-B21 Enterprise HDD
- Height
- 1.03 inches
- Width
- 5.79 inches
- Depth
- 4.01 inches
- Weight
- 1.83 lbs
875579-B21 Use Case
High-Performance Database Acceleration in Enterprise Data Centers
In a global financial services firm, the 875579-B21-HPE 480GB NVMe x4 RI M.2 22110 DS SSD is deployed to host transaction-processing databases on HPE ProLiant servers. With sustained random read/write performance above 350K IOPS and sub-100µs latency, the solution reduces query response times by 60% and increases daily transaction throughput by 2×. Businesses benefit from reduced contention during peak trading hours, compliance-grade data integrity and predictable SLA delivery.
Edge AI Inference Acceleration for Real-Time Analytics
A smart manufacturing plant integrates the 875579-B21-HPE 480GB NVMe x4 RI M.2 22110 DS SSD into HPE Edgeline servers to process video streams and sensor data for defect detection. The enterprise-grade NVMe drive delivers 4× higher sequential throughput and 5× lower latency than SATA drives, enabling sub-10ms inference times at the line side. Manufacturers gain faster quality-control decisions, reduced scrap rates and a 15% boost in overall equipment effectiveness (OEE).
Ultra-Responsive Virtual Desktop Infrastructure (VDI) Deployment
A global consulting firm implements the 875579-B21-HPE 480GB NVMe x4 RI M.2 22110 DS SSD in their HPE Synergy compute modules to host VDI gold images and user profiles. By leveraging 3GB/s sequential bandwidth and robust endurance, the SSD lowers login times by 70% and supports 200% more concurrent desktops per chassis. IT teams benefit from streamlined patch management, predictable boot storms and improved end-user experience in mission-critical remote work environments.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table 
| 875579-B21 |  Q2U11A |  875581-B21 |  875585-B21 |  P05021-B21 | |
|---|---|---|---|---|---|
| Product Type | Hard Drive | Hard Drive | Hard Drive | Hard Drive | Hard Drive |
| Drive Type | HDD | HDD | HDD | HDD | HDD |
| Use Case | Desktop / Server / NAS / Surveillance / Enterprise Storage | Desktop / Server / NAS / Surveillance | Desktop / Server / NAS / Surveillance / Enterprise Storage | Desktop / Server / NAS / Surveillance | Desktop / Server / NAS / Surveillance / Enterprise Storage |
| Interface | SATA III | SATA III | SATA III | SATA III | SATA III |
| Form Factor | 3.5-inch | 3.5-inch | 3.5-inch | 3.5-inch | 3.5-inch |
| Storage Capacity | 4 TB | 8 TB | 8 TB | 4 TB | 10 TB |
| Spindle Speed (RPM) | 7200 RPM | 7200 RPM | 7200 RPM | 7200 RPM | 7200 RPM |
| Cache (Buffer Size) | 128 MB | 256 MB | 256 MB | 128 MB | 256 MB |
| Average Latency | N/A | N/A | N/A | N/A | N/A |
| Data Transfer Rate | Up to 250 MB/s | Up to 250 MB/s | Up to 250 MB/s | Up to 250 MB/s | Up to 280 MB/s |
| Annual Workload Rating | 180 TB/yr | 550 TB/yr | 180 TB/yr | 300 TB/yr | 300 TB/yr |
| Power Consumption (Read/Write) | 8.5 Watts | 8 Watts | 7 Watts | 8 Watts | 7.2 Watts |
| Power Consumption (Idle) | 5.5 Watts | 5 Watts | 4 Watts | 4 Watts | 4.8 Watts |
| Encryption Support | AES 256-bit | AES 256-bit | AES 256-bit | AES 256-bit | AES 256-bit |
| Helium Sealed | Helium-Sealed | Helium-Sealed | Helium-Sealed | Helium-Sealed | Helium-Sealed |
| Drive Bays Supported | Multi-bay | Multi-bay | Multi-bay | Multi-bay | Multi-bay |
| Vibration Protection | Yes | Yes | Yes | Yes | Yes |
| Advanced Features | Dual Actuator | Dual Actuator | Dual Actuator | Dual Actuator | Dual Actuator |
| Operating Temperature | 5–60°C | 5–60°C | 5–60°C | 5–60°C | 5–60°C |
| Product Name | 875579-B21 Enterprise HDD | Q2U11A High-Performance Enterprise HDD | 875581-B21 | 875585-B21 Enterprise HDD | P05021-B21 |
| Height | 1.03 inches | 1.03 inches | 1.03 inches | 1.03 inches | 1.03 inches |
| Width | 5.79 inches | 5.79 inches | 5.79 inches | 4.00 inches | 5.79 inches |
| Depth | 4.01 inches | 4.00 inches | 4 inches | 5.79 inches | 4.01 inches |
| Weight | 1.83 lbs | 1.5 lbs | 2.2 lbs | 2.2 lbs | 1.92 lbs |
Reviews & Ratings
F
Furqan Ali
5
Reliable read-intensive performance.
G
George Allen
4
OEM SSD fit perfectly.
S
Salman Rauf
5
Good for OS drives.
O
Olli Nieminen
5
Consistent and efficient.
Questions & Answers
What is the storage capacity of the HPE 875579-B21 SSD?
The HPE 875579-B21 SSD offers 480 GB of raw flash storage, ideal for boot, cache, and high‐performance tiered applications.
Which interface and form factor does this SSD use?
It uses a PCIe® 3.1 NVMe™ Gen3 x4 interface in an M.2 22110 double‐sided (DS) form factor for direct board mounting.
What sequential read and write performance can I expect?
This drive delivers up to 3,200 MB/s sequential read and up to 2,000 MB/s sequential write throughput for demanding workloads.
What random I/O performance (IOPS) does the SSD deliver?
It achieves up to 400,000 random read IOPS and 160,000 random write IOPS at 4 KB transfer sizes for high concurrency.
What is the endurance rating and total bytes written (TBW)?
The SSD is rated for 0.75 drive writes per day (DWPD) over five years, equivalent to approximately 660 TB total bytes written.
What warranty does HPE provide for this drive?
HPE includes a three-year limited warranty and worldwide support, covering defects and hardware failures.
Which HPE servers and systems is the SSD compatible with?
It is validated for HPE ProLiant Gen9 and Gen10 servers, Apollo systems, Synergy frames, and select HPE edge servers with M.2 NVMe slots.
Does the HPE 875579-B21 support hardware encryption?
No. This model is optimized for read-intensive performance and does not include a self-encrypting drive (SED) feature.
How do I install the HPE M.2 22110 SSD?
Power down the server, insert the M.2 module into the onboard M.2 slot at a 30° angle, secure with the mounting screw, then reboot.
Can this SSD be used in RAID configurations?
Yes. The NVMe x4 interface supports hardware and software RAID implementations when paired with a compatible RAID controller.
What is the operating temperature range?
The drive operates between 0 °C and 70 °C (32 °F–158 °F) for ambient system temperatures.
What are the typical power consumption figures?
Power draw is roughly 6.2 W active and 2.8 W in idle, helping to balance performance with energy efficiency.
What is the MTBF (mean time between failures)?
This SSD is rated at 2 million hours MTBF, reflecting its enterprise-class reliability.
Is the drive suitable as a primary boot device?
Yes. Its read-intensive optimization and NVMe performance make it ideal for boot volumes and OS installations.
What does the 'RI' designation mean?
‘RI’ stands for Read-Intensive. The SSD is tuned for high read workloads, offering optimized endurance and performance for read-heavy applications.
What does 'M.2 22110 DS' indicate?
‘M.2 22110 DS’ refers to a 22 mm width, 110 mm length, double-sided circuit board design in the M.2 form factor.