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Name:
P00375-B21
- Description:
- HPE 2048GB NVME X4 RI M.2 2280
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3 Year Extended Warranty
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Standard ground delivery across the U.S. takes 2–6 days, depending on your location — no extra charge.
International Shipments Made Simple
For all international orders, we ship via your UPS, FedEx, or DHL account — or to your U.S.-based freight forwarder.
Delivery Timelines
Under 100 KG? Ships Express.
Smaller shipments go via DHL or FedEx Express — delivered worldwide in approximately 3 business days.
Over 100 KG? Ships via Freight.
Larger orders are dispatched through freight forwarding partners. Delivery takes 7–10 business days, globally.
Always Delivered to Your Door
Every shipment is delivered directly to your address — regardless of country or carrier.
Our best-in-class warranties
3-Year Extended Warranty
Extended protection, enterprise-grade.
All enterprise hardware is backed by a 3-year warranty — triple the industry standard — covering defects under normal use.
Professional repairs & replacements.
If a hardware issue is confirmed, we’ll repair or replace the unit. Replacement parts carry either original or 3-month coverage.
RMA process, simplified.
Once an RMA is approved, return the defective unit within 10 days. We handle the rest — no service gaps.
Service Boundaries & Exclusions
What’s covered — and what’s best avoided.
Your warranty covers defects under normal use. For continued protection, avoid accidental damage, unauthorized repairs, third-party parts, or extreme environments.
Know your location’s service type.
In some regions, return-to-factory or remote service may apply. On-site service depends on infrastructure availability.
Minimal documentation required.
To initiate service, just submit the invoice and warranty card — no red tape, no waiting.
14-Day Money Back Guarantee
Free 14-Day Returns
Tested it, but it’s not a fit?
Return any product within 14 days of delivery if it doesn’t meet your technical or operational needs.
Initiate returns with ease.
Our RMA process is streamlined — just raise a request, follow the packaging guidelines, and we’ll handle the rest.
Refund or restock, your call.
Changed your mind? Get a refund (restocking fees may apply) or swap with another product.
30-Day Hardware Replacement
Covered for any early faults.
All equipment includes a 30-day replacement warranty. If something goes wrong, we’ll repair or swap it — fast.
Replacements shipped in 10 days or less.
Once your return is inspected and approved, we dispatch the replacement promptly to keep your operations moving.
RMA protocol keeps it smooth.
Just ensure all accessories and original packaging are intact — we’ll take care of the technical validation.
TRUSTED, TRIED, PROVEN
P00375-B21 Overview
P00375-B21 is a high-performance HDD engineered in a 3.5-inch form factor and built for demanding enterprise environments. It features a SAS 12Gb/s interface, a 7200 RPM spindle speed, a robust 10 TB storage capacity, and a substantial 256 MB cache while relying on a proven design to handle mission‐critical applications.
Optimized for server, desktop, NAS, surveillance, and enterprise storage use cases, this drive is rated for an annual workload of 550 TB/yr and is designed for exceptional reliability. With low power consumption (8 Watts under read/write and 5 Watts idle), advanced helium-sealed construction, integrated vibration protection, and a dual actuator feature, P00375-B21 is suited for multi‐bay deployments in data centers and other high‐demand environments.
What is the price of P00375-B21?
Pricing for P00375-B21 is available on request. Get immediate quote or for exclusive discounts, opt for bulk quotation for P00375-B21.
Explore more options from Hard Drives & Ssds or explore other Hpe products.
P00375-B21 Specifications
| Product Type | Hard Drive |
| Drive Type | HDD |
| Use Case | Desktop / Server / NAS / Surveillance / Enterprise Storage |
| Interface | SAS 12Gb/s |
| Form Factor | 3.5-inch |
| Storage Capacity | 10 TB |
| Spindle Speed (RPM) | 7200 RPM |
| Cache (Buffer Size) | 256 MB |
| Average Latency | N/A |
| Data Transfer Rate | Up to 250 MB/s |
| Annual Workload Rating | 550 TB/yr |
| Power Consumption (Read/Write) | 8 Watts |
| Power Consumption (Idle) | 5 Watts |
| Encryption Support | AES 256-bit |
| Helium Sealed | Helium-Sealed |
| Drive Bays Supported | Multi-bay |
| Vibration Protection | Yes |
| Advanced Features | Dual Actuator |
| Operating Temperature | 5–60°C |
| Product Name | P00375-B21 |
| Height | 1.03 inches |
| Width | 5.79 inches |
| Depth | 4.00 inches |
| Weight | 1.55 lbs |
P00375-B21 Use Case
Real-Time Financial Trading Acceleration with P00375-B21-HPE 2048GB NVMe X4 RI M.2 2280
In a global investment bank’s low-latency order matching cluster, deploying the P00375-B21-HPE 2048GB NVMe X4 RI M.2 2280 module on HPE ProLiant servers delivers sub-microsecond I/O response. This use case drives a 40% uplift in transaction throughput, ensures consistent order book updates, and safeguards competitive advantage in high-frequency trading environments.
Enterprise VDI Boot Storm Mitigation with P00375-B21-HPE 2048GB NVMe X4 RI M.2 2280
A Fortune 500 corporation integrates P00375-B21-HPE 2048GB NVMe X4 RI M.2 2280 SSDs as boot volumes for 2,500 concurrent Virtual Desktop Infrastructure (VDI) instances. Resulting in 60% faster login times, near-instant desktop provisioning, and a 35% reduction in help-desk tickets, this solution optimizes end-user experience and maximizes IT resource utilization.
Edge AI Inference Acceleration with P00375-B21-HPE 2048GB NVMe X4 RI M.2 2280
A telecommunications provider deploys P00375-B21-HPE 2048GB NVMe X4 RI M.2 2280 drives in edge compute nodes to cache preprocessed sensor data for real-time AI inference. By halving data-load latency and boosting model throughput by 30%, this implementation reduces WAN backhaul, accelerates decision-making at the network edge, and supports scalable IoT analytics.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table
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| Advanced Features | Dual Actuator | Rotational Vibration Sensors | Dual Actuator | Dual Actuator | Dual Actuator |
| Annual Workload Rating | 300 TB/yr | 180 TB/yr | 550 TB/yr | 550 TB/yr | 180 TB/yr |
| Average Latency | N/A | N/A | N/A | N/A | N/A |
| Cache (Buffer Size) | 128 MB | 128 MB | 256 MB | 256 MB | 256 MB |
| Data Transfer Rate | Up to 250 MB/s | Up to 250 MB/s | Up to 250 MB/s | Up to 250 MB/s | Up to 250 MB/s |
| Depth | 4 inches | 4.02 inches | 4.0 inches | 4.00 inches | 4 inches |
| Drive Bays Supported | Multi-bay | Multi-bay | Multi-bay | Multi-bay | Multi-bay |
| Drive Type | HDD | HDD | HDD | HDD | HDD |
| Encryption Support | AES 256-bit | AES 256-bit | AES 256-bit | AES 256-bit | AES 256-bit |
| Form Factor | 3.5-inch | 3.5-inch | 3.5-inch | 3.5-inch | 3.5-inch |
| Height | 1 inches | 1.03 inches | 1.0 inches | 1.03 inches | 1.03 inches |
| Helium Sealed | Helium-Sealed | Helium-Sealed | Helium-Sealed | Helium-Sealed | Helium-Sealed |
| Interface | SATA III | SATA III | SATA III | SAS 12Gb/s | SATA III |
| Operating Temperature | 5–60°C | 5–60°C | 5–60°C | 5–60°C | 5–60°C |
| Power Consumption (Idle) | 4.5 Watts | 6.0 Watts | 5 Watts | 5 Watts | 4 Watts |
| Power Consumption (Read/Write) | 8.5 Watts | 8.0 Watts | 8 Watts | 8 Watts | 7 Watts |
| Product Name | 877829-B21 Enterprise Helium-Sealed HDD | 880264-B21 Enterprise 4TB SATA HDD | Seagate Exos X18 8TB 7200 RPM SATA III Enterprise HDD | P00375-B21 | 875581-B21 |
| Product Type | Hard Drive | Hard Drive | Hard Drive | Hard Drive | Hard Drive |
| Spindle Speed (RPM) | 7200 RPM | 7200 RPM | 7200 RPM | 7200 RPM | 7200 RPM |
| Storage Capacity | 4 TB | 4 TB | 8 TB | 10 TB | 8 TB |
| Use Case | Desktop / Server / NAS / Surveillance / Enterprise Storage | Desktop / Server / NAS / Surveillance / Enterprise Storage | Server / Enterprise Storage | Desktop / Server / NAS / Surveillance / Enterprise Storage | Desktop / Server / NAS / Surveillance / Enterprise Storage |
| Vibration Protection | Yes | Yes | Yes | Yes | Yes |
| Weight | 1.5 lbs | 1.55 lbs | 1.8 lbs | 1.55 lbs | 2.2 lbs |
| Width | 5.8 inches | 5.75 inches | 5.8 inches | 5.79 inches | 5.79 inches |
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Questions & Answers
Q
What is the storage capacity of the HPE P00375-B21 NVMe SSD?
A
The HPE P00375-B21 NVMe SSD delivers 2048 GB of usable storage capacity in an M.2 2280 form factor.
Q
Which interface and PCIe lanes does the HPE 2048GB NVMe X4 RI M.2 2280 use?
A
It uses the NVMe 1.4 protocol over a PCIe Gen4 x4 interface to maximize throughput and minimize latency.
Q
What are the sequential read and write performance specifications?
A
The drive achieves up to 7,000 MB/s sequential reads and up to 5,100 MB/s sequential writes under optimal conditions.
Q
What random IOPS can I expect from this HPE NVMe SSD?
A
It delivers up to 1.2 million random read IOPS and up to 300,000 random write IOPS at QD32.
Q
What workload profile is the HPE P00375-B21 optimized for?
A
This SSD is engineered for read-intensive (RI) data-center workloads such as boot, caching, database reads, and analytics.
Q
What endurance rating does the HPE 2048GB NVMe X4 RI drive have?
A
It is rated for 1 Drive Write per Day (DWPD) over a 5-year service life and supports up to 3,650 TB written.
Q
Is the HPE P00375-B21 hot-swappable in HPE servers?
A
Yes, it supports hot-swap operation in all HPE Gen10 and Gen11 servers with an M.2 rear-I/O slot and NVMe backplane.
Q
Which HPE server platforms are compatible with this M.2 SSD?
A
It is compatible with HPE ProLiant Gen10+ and Gen11 series servers featuring an M.2 2280 NVMe connector and appropriate BIOS support.
Q
Does the HPE 2048GB NVMe X4 RI offer built-in data encryption?
A
Yes, it supports AES-256 hardware encryption and TCG Pyrite compliance for secure data-at-rest protection.
Q
What management tools are available for monitoring this NVMe SSD?
A
You can monitor health, performance, and firmware updates using HPE Smart Storage Administrator and standard NVMe-CLI utilities.
Q
What are the operating temperature and shock tolerances?
A
The SSD operates from 0 °C to 70 °C, survives 1,500 G shock, and endures 20 G rms vibration between 10–2,000 Hz.
Q
What is the mean time between failures (MTBF) for this drive?
A
The HPE P00375-B21 NVMe SSD has an MTBF rating of 2 million hours.
Q
How do I install the HPE M.2 2280 NVMe SSD in my server?
A
Simply insert the drive into the M.2 2280 slot at a 30° angle, press down, secure it with the mounting screw, and enable NVMe support in BIOS.
Q
What power consumption should I plan for?
A
Typical active power is 6.5 W, with a maximum of 8 W during peak writes and under 50 mW in idle mode.
Q
What warranty coverage does the HPE 2048GB NVMe X4 RI include?
A
HPE provides a standard 5-year limited warranty with proactive notification of drive failures via HPE InfoSight.
