United States$5,000,000+
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Aaron Blake
4
400GB NVMe M.2 handled mixed workloads well.
875583-B21
HP 400GB NVME X4 MU M.2 22110 DS SSD
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Name:
875583-B21
- Description:
- HP 400GB NVME X4 MU M.2 22110 DS SSD
- Rating:
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- Brand:
- Hpe
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875583-B21 Overview
875583-B21 is a high-performance HDD engineered in a 3.5-inch form factor with a SATA III interface. It operates at 7200 RPM, boasts an 8 TB storage capacity with a 256 MB cache, handles a demanding annual workload rating of 550 TB/yr, and features a MTBF of 1,200,000 hours while being rated for continuous operation 8760 hours per year.
Designed with enterprise applications in mind, 875583-B21 incorporates advanced features such as a helium-sealed design, vibration protection, and dual actuator technology, all while maintaining efficient power consumption with approximately 8 Watts during read/write and 4 Watts when idle. Its robust specifications make it a reliable choice for data centers, desktops, NAS systems, and surveillance setups.
875583-B21 price is is available on request. Get immediate quote.
Request bulk order quote for 875583-B21 for additional pricing. Browse the full Hpe Server M.2&Pcie Hard Drives series or explore all Hpe products.
875583-B21 Specifications
- Width
- 4.00 inches
- Weight
- 1.75 lbs
- Form Factor
- 3.5-inch
- Product Type
- Hard Drive
- Drive Type
- HDD
- Interface
- SATA III
- Spindle Speed (RPM)
- 7200 RPM
- Average Latency
- N/A
- Data Transfer Rate
- Up to 210 MB/s
- Power Consumption (Read/Write)
- 8 Watts
- Encryption Support
- AES 256-bit
- Helium Sealed
- Helium-Sealed
- Drive Bays Supported
- Multi-bay
- Vibration Protection
- Yes
- Height
- 1.03 inches
- Cache (Buffer Size)
- 256 MB
- Annual Workload Rating
- 550 TB/yr
- Advanced Features
- Dual Actuator
- Operating Temperature
- 5–60°C
- Depth
- 5.79 inches
- Storage Capacity
- 8 TB
- Power Consumption (Idle)
- 4 Watts
- Use Case
- Server
- Product Name
- 875583-B21 Enterprise HDD
875583-B21 Use Case
Real-Time OLTP Acceleration with 875583-B21-HP 400GB NVMe x4 SSD
Scenario: A financial services firm runs high-volume MySQL OLTP workloads on HP ProLiant DL380 servers. Implementation: Deploy the 875583-B21-HP 400GB NVMe x4 MU M.2 22110 DS SSD as primary data storage. Benefit: Delivers up to 600K/180K random read/write IOPS and sub-100 µs latency, reducing query response times by 80% and boosting transaction throughput by 2.5×. Outcome: Faster analytics-driven decisions, improved SLAs and lower storage TCO.
VDI Boot & Profile Caching Optimization using 875583-B21-HP 400GB NVMe x4 SSD
Scenario: A global enterprise deploys VMware Horizon VDI on HP ProLiant DL380 hosts to support 5,000 concurrent users. Implementation: Install the 875583-B21-HP 400GB NVMe x4 MU M.2 22110 DS SSD as dedicated boot-image and user-profile cache. Benefit: Achieves up to 650/400 MB/s sequential throughput, 1000 TBW endurance and 95 µs latency, cutting login times by 60%. Outcome: Superior end-user experience, simplified management and predictable performance under heavy load.
Industrial Edge AI Inference Reliability with 875583-B21-HP 400GB NVMe x4 SSD
Scenario: A manufacturing plant implements real-time defect detection via AI inference on edge gateways in harsh environments. Implementation: Integrate the 875583-B21-HP 400GB NVMe x4 MU M.2 22110 DS SSD into ruggedized IoT appliances. Benefit: Offers compact M.2 22110 form, 2 million-hour MTBF, 3D NAND endurance and 220K sustained write IOPS, loading AI models in <100 ms. Outcome: Continuous 24/7 operation, zero downtime, improved product quality and reduced inspection costs.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table 
| 875583-B21 |  878038-B21 |  875585-B21 |  877825-B21 |  P10266-B21 | |
|---|---|---|---|---|---|
| Product Type | Hard Drive | Hard Drive | Hard Drive | Hard Drive | Hard Drive |
| Drive Type | HDD | HDD | HDD | HDD | HDD |
| Use Case | Server | Desktop / Server / NAS / Surveillance | Desktop / Server / NAS / Surveillance | Desktop / Server / NAS / Surveillance / Enterprise Storage | Desktop / Server / NAS / Surveillance / Enterprise Storage |
| Interface | SATA III | SATA III | SATA III | SATA III | SATA III |
| Form Factor | 3.5-inch | 3.5-inch | 3.5-inch | 3.5-inch | 3.5-inch |
| Storage Capacity | 8 TB | 4 TB | 4 TB | 4 TB | 10 TB |
| Spindle Speed (RPM) | 7200 RPM | 7200 RPM | 7200 RPM | 7200 RPM | 7200 RPM |
| Cache (Buffer Size) | 256 MB | 128 MB | 128 MB | 256 MB | 128 MB |
| Average Latency | N/A | N/A | N/A | N/A | N/A |
| Data Transfer Rate | Up to 210 MB/s | Up to 250 MB/s | Up to 250 MB/s | Up to 210 MB/s | Up to 250 MB/s |
| Annual Workload Rating | 550 TB/yr | 300 TB/yr | 300 TB/yr | 300 TB/yr | 300 TB/yr |
| Power Consumption (Read/Write) | 8 Watts | 8.5 Watts | 8 Watts | 6 Watts | 8 Watts |
| Power Consumption (Idle) | 4 Watts | 5 Watts | 4 Watts | 4 Watts | 5 Watts |
| Encryption Support | AES 256-bit | AES 256-bit | AES 256-bit | No | AES 256-bit |
| Helium Sealed | Helium-Sealed | Helium-Sealed | Helium-Sealed | No | Helium-Sealed |
| Drive Bays Supported | Multi-bay | Multi-bay | Multi-bay | Multi-bay | Multi-bay |
| Vibration Protection | Yes | Yes | Yes | Yes | Yes |
| Advanced Features | Dual Actuator | Dual Actuator | Dual Actuator | Rotational Vibration Sensors | Dual Actuator |
| Operating Temperature | 5–60°C | 5–60°C | 5–60°C | 5–55°C | 5–60°C |
| Product Name | 875583-B21 Enterprise HDD | 878038-B21 Enterprise HDD | 875585-B21 Enterprise HDD | 877825-B21 High Performance HDD | P10266-B21 |
| Height | 1.03 inches | 1.03 inches | 1.03 inches | 1.03 inches | 1.03 inches |
| Width | 4.00 inches | 4.00 inches | 4.00 inches | 5.79 inches | 4 inches |
| Depth | 5.79 inches | 5.8 inches | 5.79 inches | 8.26 inches | 5.79 inches |
| Weight | 1.75 lbs | 1.6 lbs | 2.2 lbs | 2.1 lbs | 1.8 lbs |
Reviews & Ratings
A
Abdul Rafay
4
Stable and responsive storage.
J
Jason Ford
5
OEM firmware worked smoothly.
H
Haseeb Khan
4
Reliable performance.
T
Thomas Bauer
4
Solid SSD option.
Questions & Answers
What is the HP 875583-B21 400GB NVMe X4 MU M.2 22110 DS SSD?
The HP 875583-B21 is a 400 GB solid-state drive in M.2 22110 form factor using PCIe Gen3 x4 NVMe protocol for high-performance storage.
What interface and protocol does this SSD use?
It uses a PCIe Gen3 x4 interface with NVMe 1.3 protocol for low-latency, high-throughput data transfers.
What are the sequential read and write speeds?
This SSD delivers up to 3,200 MB/s sequential reads and 1,500 MB/s sequential writes under typical workloads.
What form factor and dimensions does the drive have?
The drive is an M.2 22110 dual-sided (DS) module measuring 22 mm wide by 110 mm long, ideal for compact servers and workstations.
What is the endurance rating (TBW) of this SSD?
It features an endurance rating of 800 TBW (terabytes written), ensuring reliable long-term performance for enterprise workloads.
What is the mean time between failures (MTBF)?
The drive offers an MTBF of 2 million hours, demonstrating high reliability and low failure rates in mission-critical environments.
Is this SSD compatible with my server or workstation?
Yes—any motherboard or server with an M.2 22110 PCIe Gen3 x4 slot and NVMe support is compatible with this SSD.
How much power does the drive consume?
Typical active power consumption is 4.5 W, with idle power as low as 50 mW, optimizing energy efficiency in data centers.
What operating temperature range does it support?
It operates reliably from 0°C to 70°C, making it suitable for standard and extended-temperature enterprise applications.
Does the drive come with a warranty?
Yes, HP backs this SSD with a five-year limited warranty covering defects and performance failures under normal use.
How do I install the HP 875583-B21 M.2 SSD?
Power down your system, insert the M.2 22110 module into the PCIe x4 slot at a 30° angle, secure with a mounting screw, then power up and configure in BIOS.
Can this SSD be used in a RAID configuration?
Yes, you can configure multiple HP 875583-B21 drives in hardware or software RAID for enhanced performance or redundancy.
What security features are supported?
The SSD supports AES 256-bit hardware encryption and TCG Opal 2.0 for secure data protection and compliance.
How does this SSD improve overall system performance?
With high IOPS and low latency, the drive accelerates boot times, application launches, and data-intensive workloads for better responsiveness.
What makes this SSD reliable for enterprise use?
Enterprise-grade NAND, advanced wear-leveling, power-loss protection, and high endurance ensure data integrity and consistent performance.
Is firmware upgradable on this SSD?
Yes, HP provides firmware updates via the HP SSD Management Utility to optimize performance and address security patches.
What typical use cases suit this SSD?
Ideal for database servers, virtualization, high-performance computing, content creation, and any application requiring fast, durable storage.