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EPYC 7451 offers balanced performance and efficiency for mixed workloads.
881165-B21
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HPE DL385 Gen10 7451 AMD Kit
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881165-B21
- Description:
- HPE DL385 Gen10 7451 AMD Kit
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881165-B21 Overview
881165-B21 is an Intel 12th Gen processor based on the Alder Lake architecture featuring a LGA 1700 socket, 6 cores and 12 threads, a base clock speed of 2.5 GHz and a boost clock speed of 4.4 GHz, 3 MB of L2 cache paired with 18 MB of L3 cache, a thermal design power of 65W, and integrated Intel UHD Graphics 730 operating at a base frequency of 300 MHz and a maximum dynamic frequency of 1350 MHz. It supports dual-channel memory with compatibility for both DDR4 and DDR5 types and offers PCIe 5.0 connectivity.
This processor does not support overclocking and includes a stock cooler, making it well-suited for gaming and workstation applications on Intel Core-compatible chipsets. It also features virtualization support with Intel VT-x, AVX2 instruction set extensions, and basic security measures, ensuring robust performance for general use.
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881165-B21 Specifications
- Weight
- N/A
- Width
- 1.48 inches
- ECC Support
- No
- Use Case
- Gaming
- Depth
- 0.14 inches
- CPU Socket
- LGA 1700
- Memory Channels
- Dual
- PCIe Version
- PCIe 5.0
- Product Type
- Processors
- Brand
- Intel
- Virtualization Support
- Intel VT-x
- Overclocking Support
- No
- Unlocked
- No
- Series
- Intel Core
- Category
- Desktop
- Max Memory Support
- 128 GB
- Security Features
- None
- Instruction Set Extensions
- AVX2
- Graphics Base Frequency
- 300 MHz
- Memory Type Support
- DDR4 & DDR5
- Generation
- Intel 12th Gen
- Architecture
- Alder Lake
- Cooler Included
- Yes
- TDP
- 65W
- Graphics Max Dynamic Frequency
- 1350 MHz
- Height
- 1.48 inches
- Cores
- 6
- Threads
- 12
- Integrated Graphics
- Intel UHD Graphics 730
- L3 Cache
- 18 MB
- Max Boost Clock
- 4.4 GHz
- Base Clock
- 2.5 GHz
- L2 Cache
- 3 MB
- Product Name
- Intel Core i5-12400 (881165-B21)
881165-B21 Use Case
Enterprise Virtualization Consolidation with 881165-B21-HPE DL385 Gen10 7451 AMD Kit
A global financial services firm deploys the 881165-B21-HPE DL385 Gen10 7451 AMD Kit as a virtualization host for 400+ mission-critical virtual machines. Leveraging AMD EPYC™ 7451 cores and high-speed HPE memory channels, the company achieves 35% higher VM density, 25% lower power consumption, and a 40% reduction in total cost of ownership, while maintaining enterprise-grade security and SLA-driven uptime.
Real-Time Analytics and AI Inference Acceleration
A healthcare analytics provider integrates the 881165-B21-HPE DL385 Gen10 7451 AMD Kit into its on-premises cluster to process large genomic datasets and power AI inference models. The platform’s 32-core AMD EPYC™ architecture delivers sub-second query response on terabyte-scale data lakes, enabling clinicians to receive actionable insights in real time and accelerating patient diagnostics by up to 50%.
High-Throughput E-Commerce Database Infrastructure
A rapid-growing online retailer uses the 881165-B21-HPE DL385 Gen10 7451 AMD Kit to underpin its transactional database tier during peak sales events. With PCIe® Gen4 NVMe support and 8-channel memory bandwidth, the solution sustains 1M+ IOPS at ultra-low latency, ensuring seamless checkout experiences, reducing cart abandonment by 20%, and scaling automatically to meet seasonal demand spikes.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table 
| 881165-B21 |  881163-B21 |  881171-B21 |  881169-B21 |  881170-B21 | |
|---|---|---|---|---|---|
| Product Type | Processors | Processors | Processors | Processors | Processors |
| Brand | Intel | Intel | Intel | Intel | Intel |
| Series | Intel Core | Intel Core | Intel Core | Intel Core | Intel Core |
| Category | Desktop | Desktop | Desktop | Desktop | Desktop |
| Max Memory Support | 128 GB | 128 GB | 128 GB | 128 GB | 128 GB |
| Memory Type Support | DDR4 & DDR5 | DDR4 & DDR5 | DDR5 | DDR4 | DDR4 & DDR5 |
| Generation | Intel 12th Gen | Intel 13th Gen | Intel 13th Gen | Intel 13th Gen | Intel 12th Gen |
| Architecture | Alder Lake | Raptor Lake | Raptor Lake | Raptor Lake | Alder Lake |
| ECC Support | No | No | No | No | No |
| Security Features | None | SGX | SGX | None | None |
| CPU Socket | LGA 1700 | LGA 1700 | LGA 1700 | LGA 1700 | LGA 1700 |
| Instruction Set Extensions | AVX2 | AVX2 | AVX2 | AVX2 | AVX2 |
| Virtualization Support | Intel VT-x | Intel VT-x | Intel VT-x | Intel VT-x | Intel VT-x |
| Cores | 6 | 8 | 8 | 8 | 12 |
| Threads | 12 | 16 | 16 | 16 | 20 |
| Base Clock | 2.5 GHz | 3.8 | 3.6 GHz | 3.6 | 3.6 GHz |
| Max Boost Clock | 4.4 GHz | 5.0 | 5.0 GHz | 5.0 | 5.0 GHz |
| Overclocking Support | No | No | Yes | Yes | Yes |
| L2 Cache | 3 MB | 8 | 4 MB | 4 | 12 MB |
| L3 Cache | 18 MB | 16 | 16 MB | 16 | 25 MB |
| TDP | 65W | 125W | 125W | 125W | 125W |
| Integrated Graphics | Intel UHD Graphics 730 | Intel UHD Graphics 770 | Intel UHD Graphics 770 | Intel UHD Graphics 770 | Intel UHD Graphics 770 |
| Graphics Base Frequency | 300 MHz | 300 | N/A | 350 | 350 MHz |
| Graphics Max Dynamic Frequency | 1350 MHz | 1100 | N/A | 1150 | 1200 MHz |
| Memory Channels | Dual | Dual | Dual | Dual | Dual |
| PCIe Version | PCIe 5.0 | PCIe 5.0 | PCIe 5.0 | PCIe 5.0 | PCIe 5.0 |
| Unlocked | No | No | Yes | Yes | Yes |
| Cooler Included | Yes | No | No | No | No |
| Use Case | Gaming | Gaming | Gaming / Workstation / General Use | Gaming | Gaming / Workstation |
| Product Name | Intel Core i5-12400 (881165-B21) | Intel Core i7 881163-B21 | Intel Core i7-13700K | 881169-B21 Processor | Intel Core i7-12700K Processor |
| Height | 1.48 inches | N/A | N/A | 0.2 inches | N/A |
| Width | 1.48 inches | N/A | N/A | 1.6 inches | N/A |
| Depth | 0.14 inches | N/A | N/A | 1.6 inches | N/A |
| Weight | N/A | N/A | N/A | 0.25 lbs | N/A |
Reviews & Ratings
S
Shahbaz Ali
4
Stable operation during continuous production use.
O
Olli Korpela
5
Installed easily and worked as expected.
R
Ryan Coleman
5
Good processor for enterprise virtualization clusters.
I
Imran Saeed
5
Predictable results in production.
Questions & Answers
What is the HPE DL385 Gen10 7451 AMD Kit (SKU 881165-B21)?
The HPE DL385 Gen10 7451 AMD Kit is a server upgrade module for HPE ProLiant DL385 Gen10 featuring dual AMD EPYC 7451 processors, heatsinks and CPU trays to boost compute performance.
Which processors are included in the HPE DL385 Gen10 7451 AMD Kit?
This kit includes two AMD EPYC 7451 24-core processors running at 2.3 GHz (up to 3.2 GHz boost) with 64 MB L3 cache each.
What memory configuration does the DL385 Gen10 support with this AMD kit?
When populated with the 7451 AMD Kit, the DL385 Gen10 supports up to 2 TB of DDR4 memory across 16 RDIMM/LRDIMM slots at up to 2 666 MT/s.
What storage options are available on the HPE DL385 Gen10 with this kit?
The server supports up to 24 SFF (2.5″) SAS/SATA drives or up to 12 SFF NVMe drives, plus optional M.2 boot and HPE Smart Array controllers.
What networking capabilities are provided with the 7451 AMD Kit?
Built-in networking includes dual 1 GbE ports and FlexibleLOM slots for 10/25/100 GbE adapters to match your data center requirements.
Which operating systems are supported by the DL385 Gen10 7451 AMD Kit?
HPE ProLiant DL385 Gen10 with the AMD Kit supports Windows Server, Red Hat Enterprise Linux, SUSE Linux Enterprise Server and VMware ESXi.
Is the HPE DL385 Gen10 7451 AMD Kit virtualization-ready?
Yes. It is certified for major hypervisors including VMware vSphere, Microsoft Hyper-V and Red Hat KVM for enterprise virtualization and cloud deployments.
How do I install the HPE DL385 Gen10 7451 AMD Kit?
Installation involves powering down the server, replacing the existing CPU tray with the 7451 AMD tray, seating the processors into the sockets, applying thermal paste, attaching heatsinks and updating firmware.
Can I upgrade my existing DL385 Gen10 server with the SKU 881165-B21 AMD Kit?
Yes. Your Gen10 chassis only requires a BIOS/firmware update to support the AMD EPYC 7451 kit and a compatible power/cooling configuration.
What built-in security features are included with this AMD kit?
Security features include HPE Silicon Root of Trust, Secure Boot, TPM 2.0, runtime firmware validation and chassis intrusion detection.
What remote management capabilities does the DL385 Gen10 7451 AMD Kit offer?
It includes HPE Integrated Lights-Out (iLO 5) for remote monitoring, management, firmware updates, secure console access and automated maintenance.
What warranty and support options are available for the 7451 AMD Kit?
HPE provides a 3-year limited warranty with 24×7 phone support, parts replacement and optional Proactive Care or Foundation Care service upgrades.
What power efficiency features are available with the DL385 Gen10 AMD configuration?
Features include HPE Power Discovery Services, Platinum-rated redundant power supplies, intelligent power capping and multi-fan cooling for optimized energy use.
What cooling requirements does the HPE DL385 Gen10 7451 AMD Kit have?
The 2U rack server uses redundant hot-plug fans and an optimized airflow design; ensure adequate front-to-back rack ventilation and ambient temperature below 30 °C.
What are the primary use cases for the HPE DL385 Gen10 7451 AMD Kit?
This configuration is ideal for virtualization, database workloads, high-performance computing, cloud infrastructure and software-defined environments.