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EPYC 7281 provides balanced performance and efficiency.
P00645-B21
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HPE DL385 Gen10 7281 AMD EPYC Kit
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Name:
P00645-B21
- Description:
- HPE DL385 Gen10 7281 AMD EPYC Kit
- Rating:
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P00645-B21 Overview
P00645-B21 is an Intel processor from the Intel 13th Gen Raptor Lake family built on the latest Intel architecture. It features 16 cores and 24 threads with a base clock speed of 3.4 GHz and a boost clock of 5.2 GHz, paired with 16 MB of L2 cache and 30 MB of L3 cache. The unit is designed for the LGA 1700 socket and offers a thermal design power of 125W along with integrated Intel UHD Graphics 770.
This processor supports both DDR4 and DDR5 memory through dual channels, provides PCIe 5.0 connectivity, and includes overclocking support for enhanced performance. Its feature set, including Intel VT-x virtualization, AVX2 instruction extensions, and an integrated graphics base frequency of 350 MHz that can dynamically reach up to 1250 MHz, makes it ideally suited for demanding gaming, workstation, and high-performance desktop environments.
P00645-B21 price is is available on request. Get immediate quote.
Request bulk order quote for P00645-B21 for additional pricing. Browse the full Hpe Dl385 Server Processors series or explore all Hpe products.
P00645-B21 Specifications
- Product Type
- Processors
- Brand
- Intel
- Series
- Intel Core
- Category
- Desktop
- Max Memory Support
- 128 GB
- Memory Type Support
- DDR4 & DDR5
- Generation
- Intel 13th Gen
- Architecture
- Raptor Lake
- ECC Support
- No
- Security Features
- None
- CPU Socket
- LGA 1700
- Instruction Set Extensions
- AVX2
- Virtualization Support
- Intel VT-x
- Cores
- 16
- Threads
- 24
- Base Clock
- 3.4
- Max Boost Clock
- 5.2
- Overclocking Support
- Yes
- L2 Cache
- 16
- L3 Cache
- 30
- TDP
- 125W
- Integrated Graphics
- Intel UHD Graphics 770
- Graphics Base Frequency
- 350
- Graphics Max Dynamic Frequency
- 1250
- Memory Channels
- Dual
- PCIe Version
- PCIe 5.0
- Unlocked
- Yes
- Cooler Included
- No
- Use Case
- Gaming
- Product Name
- Intel Core i7-13700K
- Height
- 0.18 inches
- Width
- 1.48 inches
- Depth
- 1.48 inches
- Weight
- N/A
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table 
| P00645-B21 |  881163-L21 |  P00645-L21 |  881164-B21 |  881170-L21 | |
|---|---|---|---|---|---|
| Product Type | Processors | Processors | Processors | Processors | Processors |
| Brand | Intel | Intel | Intel | Intel | Intel |
| Series | Intel Core | Intel Core | Intel Core | Intel Core | Intel Core |
| Category | Desktop | Desktop | Desktop | Desktop | Desktop |
| Max Memory Support | 128 GB | 128 GB | 128 GB | 128 GB | 128 GB |
| Memory Type Support | DDR4 & DDR5 | DDR5 | DDR4 & DDR5 | DDR4 & DDR5 | DDR5 |
| Generation | Intel 13th Gen | Intel 13th Gen | Intel 12th Gen | Intel 12th Gen | Intel 12th Gen |
| Architecture | Raptor Lake | Raptor Lake | Alder Lake | Alder Lake | Alder Lake |
| ECC Support | No | No | No | No | No |
| Security Features | None | None | SGX | None | N/A |
| CPU Socket | LGA 1700 | LGA 1700 | LGA 1700 | LGA 1700 | LGA 1700 |
| Instruction Set Extensions | AVX2 | AVX2 | AVX2 | AVX2 | AVX2 |
| Virtualization Support | Intel VT-x | Intel VT-x | Intel VT-x | Intel VT-x | Intel VT-x |
| Cores | 16 | 8 | 8 | 8 | 10 |
| Threads | 24 | 16 | 16 | 16 | 16 |
| Base Clock | 3.4 | 3.6 | 3.6 | 3.8 GHz | 3.6 |
| Max Boost Clock | 5.2 | 5.0 | 4.9 | 4.5 GHz | 4.9 |
| Overclocking Support | Yes | Yes | Yes | Yes | Yes |
| L2 Cache | 16 | 4 | 8 | 4 MB | 5 |
| L3 Cache | 30 | 16 | 20 | 16 MB | 20 |
| TDP | 125W | 125W | 125W | 125W | 125W |
| Integrated Graphics | Intel UHD Graphics 770 | Intel UHD Graphics 770 | Intel UHD Graphics 770 | Intel UHD Graphics 770 | Intel UHD Graphics 770 |
| Graphics Base Frequency | 350 | 300 | 300 | 350 MHz | 350 |
| Graphics Max Dynamic Frequency | 1250 | 1200 | 1200 | 1100 MHz | 1100 |
| Memory Channels | Dual | Dual | Dual | Dual | Dual |
| PCIe Version | PCIe 5.0 | PCIe 5.0 | PCIe 5.0 | PCIe 5.0 | PCIe 5.0 |
| Unlocked | Yes | Yes | Yes | Yes | Yes |
| Cooler Included | No | No | No | No | No |
| Use Case | Gaming | Gaming | Gaming | Gaming | Gaming |
| Product Name | Intel Core i7-13700K | 881163-L21 | Intel Core P00645-L21 | Intel Core i7-12700K | Intel Core i7-12700K Processor |
| Height | 0.18 inches | 1.5 | 0.6 inches | 0.5 inches | 0.6 |
| Width | 1.48 inches | 1.5 | 1.4 inches | 1.5 inches | 1.5 |
| Depth | 1.48 inches | 1.2 | 1.4 inches | 1.5 inches | 1.5 |
| Weight | N/A | 0.25 | 0.3 lbs | 0.25 lbs | 0.3 |
Reviews & Ratings
U
Usman Farid
5
Stable under continuous virtualization workloads.
T
Teemu Laaksonen
5
Deployment was straightforward.
C
Chris Whitman
5
Good option for scalable environments.
H
Hammad Saleem
4
Reliable AMD platform.
Questions & Answers
What is the HPE DL385 Gen10 7281 AMD EPYC Kit (SKU: P00645-B21)?
The HPE DL385 Gen10 7281 AMD EPYC Kit (P00645-B21) is a factory-integrated upgrade module that adds a 16-core AMD EPYC 7281 CPU to the ProLiant DL385 Gen10 server, optimizing compute density and throughput for data-center workloads.
Which processor model is included in this kit?
This kit includes the AMD EPYC 7281 processor, featuring 16 cores, 32 threads, a 2.1 GHz base clock, and up to 2.7 GHz boost clock for balanced compute performance.
How many memory channels and DIMMs does the AMD EPYC 7281 support?
The AMD EPYC 7281 supports eight memory channels with two DIMMs per channel, for a maximum of 2 TB DDR4 RDIMM/LRDIMM per socket when paired with HPE SmartMemory.
What is the thermal design power (TDP) of the AMD EPYC 7281?
The AMD EPYC 7281 operates with a 155 W TDP, enabling high performance within the ProLiant DL385 Gen10’s thermal and power envelope.
Is a BIOS update required before installing this kit?
Yes. Ensure the ProLiant DL385 Gen10 server is running HPE BIOS version 2.01 or later to guarantee full compatibility and optimal performance with the AMD EPYC 7281.
Can I deploy two AMD EPYC 7281 kits for a dual-socket configuration?
Yes. The ProLiant DL385 Gen10 server supports dual-socket operation. Installing two P00645-B21 kits enables up to 32 cores and 64 threads in a single system.
Which PCIe generation does the AMD EPYC 7281 support?
The AMD EPYC 7281 provides 128 lanes of PCIe 3.0, delivering ample bandwidth for high-performance storage, networking, and accelerator cards.
What virtualization features are enabled by this kit?
The AMD EPYC 7281 includes AMD-V virtualization, Secure Encrypted Virtualization (SEV), and rapid guest isolation to enhance hypervisor performance and multi-tenant security.
What workloads benefit most from the HPE DL385 Gen10 7281 EPYC Kit?
This kit excels in virtualization, database management, HPC, and analytics by providing balanced core density, memory bandwidth, and I/O throughput.
Are HPE SmartMemory modules required with this processor?
For warranty compliance and to achieve rated performance, use HPE SmartMemory DDR4 RDIMM or LRDIMM modules validated for ProLiant DL385 Gen10.
What is the warranty coverage for SKU P00645-B21?
The kit is covered by HPE’s standard three-year limited warranty with parts, labor, and on-site support, subject to local service–level agreements.
How do I install the AMD EPYC 7281 kit in my DL385 Gen10?
Power down the server, remove the existing CPU tray, seat the AMD EPYC 7281 module into the socket, apply thermal interface material, reinstall the heat sink, and update BIOS as recommended.
What cooling requirements does the EPYC 7281 impose?
Use HPE ProLiant Gen10 thermal solutions designed for 155 W TDP CPUs. Ensure proper airflow and heat-sink orientation as outlined in the server installation guide.
Can I mix AMD EPYC and Intel CPUs in the same chassis?
No. The ProLiant DL385 Gen10 only supports AMD EPYC processors in its sockets; mixing architectures is not supported.
Is remote management available with this kit?
Yes. Remote server management is provided via HPE iLO 5, enabling secure firmware updates, health monitoring, and power control for systems equipped with AMD EPYC.
What firmware versions are recommended for optimal security?
Use the latest HPE Service Pack for ProLiant (SPP) to ensure up-to-date BIOS, iLO, and firmware components that protect against known vulnerabilities.