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Cisco ONE licensing made setup quick. Stable router for small branches.
C1-CISCO4221/K9
Cisco One -Cisco ISR 4221 (2GE, 2NIM, 8G FLASH, 4G DRAM, IPB...
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Name:
C1-CISCO4221/K9
- Description:
- Cisco One -Cisco ISR 4221 (2GE, 2NIM, 8G FLASH, 4G DRAM, IPB)
- Rating:
Added to cart 28 times recently
- Availability:
In stock - Ready to Ship
- Brand:
- Cisco
- GTIN:
- 818249335827
- Condition:
- Warranty:
- 3
- List Price:
$2,327.00
- Price:
$1,000.0057% off
Quantity:
1
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C1-CISCO4221/K9 Overview
C1-CISCO4221/K9 is a high-performance integrated router built on a fixed architecture with dual power options that ensure reliable operation in demanding branch office environments. It features dual WAN interfaces paired with four LAN ports, delivering robust connectivity and integrated services designed for secure, high-throughput data, voice, and video transmission.
C1-CISCO4221/K9 offers modular expansion capabilities with two dedicated EHWIC slots, advanced VPN features for secure remote access, and redundancy options to support mission-critical operations. Its optimized performance, quality of service, and integrated firewall and intrusion prevention functionalities make it an ideal solution for enterprise branch deployments requiring efficient and secure networking.
C1-CISCO4221/K9 price is $1,000.00, a 57% saving from the Cisco list price of $2,327.00. C1-CISCO4221/K9 is in stock and available for next-day dispatch. (terms applied)
Request bulk order quote for C1-CISCO4221/K9 for additional pricing. Browse the full Router Isr 4000 series or explore all Cisco products.
C1-CISCO4221/K9 Specifications
- Product Type
- Enterprise Router
- VPN Support
- IPSec / DMVPN / FlexVPN / N/A
- Power Source
- AC Power Supply / N/A
- Routing Protocols
- OSPF / BGP / EIGRP / RIP / Static Routing
- Broadband
- N/A
- Architecture
- Fixed
- WAN Configuration
- Dual WAN
- WAN Ports
- 2 WAN
- LAN Ports
- 4 LAN Ports
- Ethernet Technology
- 10/100/1000
- Wi-Fi Standard
- N/A
- Connectivity Type
- Wired
- Network Protocols
- IPv4, IPv6, MPLS
- Remote Management
- CLI, WebUI, SNMP
- Compliance Standards
- FCC, CE, UL
- Wireless Support
- No
- Speed/Capacity
- Gigabit
- Firewall Features
- Yes
- Features
- VPN / VoIP / IPv6 Compatible / Firewall
- Use Case
- Enterprise
- Management
- Managed
- Form Factor
- Rack-mount
- Integrated Services
- Voice / Video
- High Availability Support
- Supported
- Safety
- UL, CE
- EMC
- FCC, CE
- Telecom
- N/A
- Throughput Capacity
- 0.075 Gbps
- QoS Features
- Supported
- Built-in Security Features
- Firewall / Intrusion Prevention / Malware Protection
- Expansion Slots
- EHWIC
- Modular Slots Available
- 2 Slots
- Stacking Capability
- No
- 5G Support
- No
- Memory
- 2 GB
- Flash Memory
- 256 MB
- Interface Ports
- RJ-45
- Power
- 80 Watt
- Device Type
- Router
- Product Name
- Cisco 4221 Integrated Services Router
- Height
- 1.73 inches
- Width
- 17.3 inches
- Depth
- 10.1 inches
- Weight
- 15.7 lbs
C1-CISCO4221/K9 Use Case
SD-WAN Optimization and Analytics for Multi-Site Retail with Cisco ISR 4221
A nationwide retail chain deploys the C1-CISCO4221/K9-Cisco One Cisco ISR 4221 at 100+ stores to enable Cisco SD-WAN, real-time application prioritization and integrated security. Using 2GE ports and 2 NIM slots for wireless failover, the solution delivers dynamic path selection, end-to-end encryption and centralized policy management. Outcome: 30% lower WAN costs, 40% faster POS transactions and unified network visibility across all locations.
Encrypted VPN Gateway and Zero-Trust Access for Financial Branches
A regional bank leverages the Cisco ISR 4221 (C1-CISCO4221/K9-Cisco One) as a hardware-accelerated IPsec VPN gateway in 75 remote branches. With 8 GB flash, 4 GB DRAM and built-in firewall, each ISR 4221 enforces identity-based policies, PCI DSS compliance and 256-bit encryption over MPLS and broadband links. Benefit: 99.9% uptime, simplified regulatory audits and granular control of user and application access.
IoT Edge Aggregation and Secure Connectivity in Smart Manufacturing
A smart manufacturing plant installs Cisco ISR 4221 (C1-CISCO4221/K9-Cisco One) to aggregate industrial IoT sensors, PLC controllers and CCTV feeds. The router’s 2GE uplinks, 2 NIM slots for LTE backup and Cisco Trustworthy Solutions hardware root-of-trust isolate OT traffic and prevent lateral threats. Result: 24/7 operational visibility, 20% reduction in unplanned downtime and robust segmentation of IT and OT networks.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table
 C1-CISCO4221/K9 |  C1-CISCO4321/K9 |  ISR4451-X-V/K9 |  ISR4431-VSEC/K9 |  C1-CISCO4451/K9 | |
|---|---|---|---|---|---|
| 5G Support | No | No | No | No | No |
| Architecture | Fixed | Modular | Modular | Modular | Modular |
| Broadband | N/A | N/A | N/A | N/A | N/A |
| Built-in Security Features | Firewall / Intrusion Prevention / Malware Protection | Firewall / Intrusion Prevention | Firewall / Intrusion Prevention / Malware Protection | Firewall / Intrusion Prevention / Malware Protection | Firewall, Intrusion Prevention, Malware Protection |
| Compliance Standards | FCC, CE, UL | FCC / CE | FCC / CE / UL | FCC, CE, UL | FCC, CE |
| Connectivity Type | Wired | Wired | Ethernet | Wired | Wired |
| Depth | 10.1 inches | 20 inches | 18 inches | N/A | 18 inches |
| Device Type | Router | Router | Router | Router | Router |
| EMC | FCC, CE | N/A | N/A | FCC, CE | N/A |
| Ethernet Technology | 10/100/1000 | 10/100/1000 | 10/100/1000 | 10/100/1000 | 10/100/1000 |
| Expansion Slots | EHWIC | NIM / EHWIC | NIM | NIM | EHWIC / NIM |
| Features | VPN / VoIP / IPv6 Compatible / Firewall | VPN / VoIP / IPv6 Compatible / Firewall / WAN Optimization | VPN / VoIP / IPv6 Compatible / Firewall / MPLS | VPN / Firewall / IPS / Intrusion Prevention / IPv6 Compatible | VPN, VoIP, IPv6 Compatible, Firewall, MPLS |
| Firewall Features | Yes | Yes | Yes | Yes | Yes |
| Flash Memory | 256 MB | 512 MB | 2 GB | 2 GB | 2 GB |
| Form Factor | Rack-mount | Rack-mount | Rack-mount | Rack-mount | Rack-mount |
| Height | 1.73 inches | 1.75 inches | 1.75 inches | N/A | 1.75 inches |
| High Availability Support | Supported | Supported | Supported | Supported | Supported |
| Integrated Services | Voice / Video | Voice / Video / WAN Optimization | Voice / Video / WAN Optimization | Voice / Video / WAN Optimization | Voice, Video, WAN Optimization |
| Interface Ports | RJ-45 | RJ-45 / SFP | RJ-45 / SFP | RJ-45 / SFP / Combo Ports | RJ-45, SFP, Combo Ports |
| LAN Ports | 4 LAN Ports | Modular LAN | Modular LAN | Modular LAN | Modular LAN |
| Management | Managed | Managed | Managed | Managed | Managed |
| Memory | 2 GB | 1 GB | 4 GB | 4 GB | 4 GB |
| Modular Slots Available | 2 Slots | 2 Slots | 3+ Slots | 3+ Slots | 3+ Slots |
| Network Protocols | IPv4, IPv6, MPLS | IPv4, IPv6 | IPv4, IPv6, MPLS | IPv4, IPv6, MPLS | IPv4, IPv6 |
| Power | 80 Watt | 110 W | 370W | 350 W | 250 W |
| Power Source | AC Power Supply / N/A | AC Power Supply with Redundant Options | AC Power Supply / Redundant | AC Power Supply / Redundant | AC Power Supply / Redundant |
| Product Name | Cisco 4221 Integrated Services Router | Cisco 4321 Integrated Services Router (C1-CISCO4321/K9) | Cisco ISR4451-X-V/K9 | Cisco ISR4431-VSEC/K9 | Cisco 4451 Integrated Services Router |
| Product Type | Enterprise Router | Enterprise Router | Enterprise Router | Enterprise Router | Enterprise Router |
| QoS Features | Supported | Supported | Supported | Supported | Supported |
| Remote Management | CLI, WebUI, SNMP | SSH / Telnet / SNMP | SSH / Telnet / SNMP | SSH, Telnet, SNMP, NetConf | CLI, SNMP, Telnet, SSH |
| Routing Protocols | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / IS-IS / RIP / Static Routing / MPLS | OSPF / BGP / EIGRP / MPLS / IS-IS / RIP / Static Routing / N/A | OSPF / BGP / EIGRP / MPLS / IS-IS / RIP / Static Routing |
| Safety | UL, CE | N/A | N/A | UL Listed | N/A |
| Speed/Capacity | Gigabit | Gigabit | Gigabit | Gigabit | Gigabit |
| Stacking Capability | No | No | No | Yes | No |
| Telecom | N/A | N/A | N/A | N/A | N/A |
| Throughput Capacity | 0.075 Gbps | 0.15 Gbps | 2 Gbps | 1 Gbps | 2 Gbps |
| Use Case | Enterprise | Enterprise | Enterprise | Enterprise | Enterprise |
| VPN Support | IPSec / DMVPN / FlexVPN / N/A | IPSec / SSL VPN / DMVPN / FlexVPN | IPSec / SSL VPN / GRE / DMVPN / FlexVPN | IPSec / SSL VPN / GRE / DMVPN / FlexVPN / N/A | IPSec / SSL VPN / GRE / DMVPN / FlexVPN / N/A |
| WAN Configuration | Dual WAN | Dual WAN | Modular WAN | Dual WAN | Dual WAN |
| WAN Ports | 2 WAN | 2 WAN | Modular WAN | Modular WAN | Modular WAN |
| Weight | 15.7 lbs | 14 lbs | 30 lbs | N/A | 23 lbs |
| Wi-Fi Standard | N/A | N/A | N/A | N/A | N/A |
| Width | 17.3 inches | 17.5 inches | 17.5 inches | N/A | 17.5 inches |
| Wireless Support | No | No | No | No | No |
Reviews & Ratings
M
Mark Ellison
4
Reliable ISR with good performance for its size.
J
James Thornton
5
Consistent uptime and easy configuration. Meets basic enterprise needs.
S
Steven Palmer
3
Good entry level ISR with Cisco reliability.
B
Brian Fletcher
4
Solid router for secure branch connectivity.
Questions & Answers
What is the Cisco ISR 4221 and which use cases does it serve?
Cisco ISR 4221 is a compact branch router delivering secure WAN, LAN and cloud connectivity with up to 50 Mbps aggregate throughput, ideal for small offices and distributed enterprise sites.
What licensing options are available for Cisco ISR 4221?
Cisco ISR 4221 supports Cisco One subscriptions for software feature bundles (IP Base, Security, Unified Communications) as well as traditional perpetual licenses, enabling flexible deployment and upgrade paths.
What is included in the Cisco One software subscription for ISR 4221?
Cisco One provides a single subscription that bundles software updates, new feature releases and unified support across IP Base, Security and Application Experience licenses for ISR 4221.
What are the performance specifications of the ISR 4221 router?
ISR 4221 delivers up to 50 Mbps of aggregate performance, two 10/100/1000 Ethernet ports, hardware acceleration for security and QoS, and the ability to scale with Service Performance Levels.