Name:
ISR4221-AX/K9
- Description:
- Cisco ISR 4221 AX Bundle w/APP, SEC lic
- Rating:
-
(0)
Added to cart 8 times recently
- Availability:
-
In stock - Ready to Ship
- Brand:
- Cisco
- Condition:
- GTIN:
- 659821191628
- Warranty:
-
3 - List Price:
-
- Price:
-
3 Year Extended Warranty
Same-day Shipping
14-Day Money Back Guarantee
Need Additional Discount on Product?
Request a quote below - Get Exclusive Pricing and Support.
Exclusive Bulk Discounts tailored to your order size
Priority Processing with a dedicated account manager
Fast Response: Get your custom quote within 5-10 minutes during business hours (Mon-Fri, 6:00 AM – 6:00 PM PST)
Holiday Bonus: Submissions on holidays receive priority handling the next business day
Shipping:
Payment:
Shipping as per your need
Same-day Shipping
Express Delivery Across the USA
Need it fast? Choose Express Shipping and receive your order within 1–3 business days.
Free Ground Shipping Available
Standard ground delivery across the U.S. takes 2–6 days, depending on your location — no extra charge.
International Shipments Made Simple
For all international orders, we ship via your UPS, FedEx, or DHL account — or to your U.S.-based freight forwarder.
Delivery Timelines
Under 100 KG? Ships Express.
Smaller shipments go via DHL or FedEx Express — delivered worldwide in approximately 3 business days.
Over 100 KG? Ships via Freight.
Larger orders are dispatched through freight forwarding partners. Delivery takes 7–10 business days, globally.
Always Delivered to Your Door
Every shipment is delivered directly to your address — regardless of country or carrier.
14-Day Money Back Guarantee
Free 14-Day Returns
Tested it, but it’s not a fit?
Return any product within 14 days of delivery if it doesn’t meet your technical or operational needs.
Initiate returns with ease.
Our RMA process is streamlined — just raise a request, follow the packaging guidelines, and we’ll handle the rest.
Refund or restock, your call.
Changed your mind? Get a refund (restocking fees may apply) or swap with another product.
30-Day Hardware Replacement
Covered for any early faults.
All equipment includes a 30-day replacement warranty. If something goes wrong, we’ll repair or swap it — fast.
Replacements shipped in 10 days or less.
Once your return is inspected and approved, we dispatch the replacement promptly to keep your operations moving.
RMA protocol keeps it smooth.
Just ensure all accessories and original packaging are intact — we’ll take care of the technical validation.
TRUSTED, TRIED, PROVEN
ISR4221-AX/K9 Overview
ISR4221-AX/K9 is a robust enterprise router featuring a fixed architecture optimized for secure branch connectivity with integrated VPN, firewall, and advanced security services. It supports flexible power options with an AC power supply while providing modular expansion capabilities to address evolving network demands.
ISR4221-AX/K9 delivers comprehensive WAN/LAN interfaces with dual WAN ports and four LAN ports operating at 10/100/1000 speeds, and integrates services including voice, video, and WAN optimization. Its high throughput, reliable VPN features, and performance-enhanced design make it an ideal choice for enterprise branch offices, small businesses, and remote sites needing secure and scalable connectivity.
What is the price of ISR4221-AX/K9?
Pricing for ISR4221-AX/K9 is available on request. Get immediate quote or for exclusive discounts, opt for bulk quotation for ISR4221-AX/K9.
Explore more options from Routers or explore other Cisco products.
ISR4221-AX/K9 Specifications
| Product Type | Enterprise Router |
| VPN Support | IPSec / SSL VPN |
| Power Source | AC Power Supply |
| Routing Protocols | OSPF / BGP / EIGRP / RIP / Static Routing |
| Broadband | N/A |
| Architecture | Fixed |
| WAN Configuration | Dual WAN |
| WAN Ports | 2 WAN |
| LAN Ports | 4 LAN Ports |
| Ethernet Technology | 10/100/1000 |
| Wi-Fi Standard | N/A |
| Connectivity Type | Wired |
| Network Protocols | IPv4, IPv6, MPLS |
| Remote Management | SSH, Telnet, SNMP |
| Compliance Standards | FCC / CE / UL |
| Wireless Support | No |
| Speed/Capacity | Gigabit |
| Firewall Features | Yes |
| Features | VPN / Firewall / IPv6 Compatible |
| Use Case | Enterprise / Branch Office |
| Management | Managed |
| Form Factor | Rack-mount |
| Integrated Services | Voice / Video / WAN Optimization |
| High Availability Support | Not Supported |
| Safety | N/A |
| EMC | N/A |
| Telecom | N/A |
| Throughput Capacity | 0.25 Gbps |
| QoS Features | Supported |
| Built-in Security Features | Firewall / Intrusion Prevention |
| Expansion Slots | EHWIC / NIM |
| Modular Slots Available | 1 Slot |
| Stacking Capability | No |
| 5G Support | No |
| Memory | 1 GB |
| Flash Memory | 256 MB |
| Interface Ports | RJ-45, SFP |
| Power | 70 Watt |
| Device Type | Router |
| Product Name | Cisco ISR 4221 Integrated Services Router |
| Height | 1.75 inches |
| Width | 17.6 inches |
| Depth | 12 inches |
| Weight | 10 lbs |
ISR4221-AX/K9 Use Case
ISR4221-AX/K9 for Secure Branch Office Connectivity
A multinational retail chain deploys Cisco ISR 4221 AX Bundle w/APP, SEC lic at new branch locations to establish encrypted IPsec VPN tunnels, enable next-generation firewall and intrusion prevention. Outcome: Unified, zero-trust network segmentation across 50+ sites, 40% reduction in security incidents and full compliance with PCI DSS.
Application-Aware SD-WAN Optimization with ISR4221-AX/K9
A global professional services firm leverages the ISR 4221 AX APP license to dynamically route critical SaaS and UC traffic over broadband or MPLS links based on real-time performance metrics. Outcome: Consistent sub-50 ms latency for cloud applications, 30% lower WAN costs and centralized policy enforcement via Cisco DNA Center.
Hybrid Cloud On-Ramp and Secure IaaS Connectivity
A mid-market manufacturing company uses Cisco ISR 4221 AX Bundle w/APP, SEC lic as a dedicated on-ramp router to AWS and Azure, combining DMVPN, direct connect and integrated threat defense. Outcome: 50% faster cloud workload provisioning, end-to-end encryption, and unified security posture across on-premises and public cloud environments.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table
|
|
|
|
|
|
|
|---|---|---|---|---|---|
| 5G Support | No | No | No | No | No |
| Architecture | Fixed | Modular | Modular | Fixed | Modular |
| Broadband | N/A | N/A | N/A | N/A | N/A |
| Built-in Security Features | Firewall, Intrusion Prevention, Malware Protection | Firewall / Intrusion Prevention / Malware Protection | Firewall / Intrusion Prevention / Malware Protection | Firewall / Intrusion Prevention | Firewall / Intrusion Prevention / Malware Protection |
| Compliance Standards | FCC, CE | FCC / CE / UL | IEEE / FCC / CE | FCC / CE / UL | FCC / CE |
| Connectivity Type | Wired | Wired | Wired | Wired | Wired |
| Depth | N/A | 15.1 inches | N/A | 12 inches | N/A |
| Device Type | Router | Router | Router | Router | Router |
| EMC | N/A | N/A | N/A | N/A | N/A |
| Ethernet Technology | 10/100/1000 | 10/100/1000 | 10/100/1000 | 10/100/1000 | 10/100/1000 |
| Expansion Slots | NIM, EHWIC | NIM | EHWIC / NIM / SFP+ | EHWIC / NIM | EHWIC |
| Features | VPN, Firewall, IPv6 Compatible | VPN / IPv6 Compatible / Firewall / MPLS | VPN / Firewall / VoIP / IPv6 Compatible / MPLS / Integrated Services | VPN / Firewall / IPv6 Compatible | VPN / Firewall / Voice / Video / WAN Optimization |
| Firewall Features | Yes | Yes | Yes | Yes | Yes |
| Flash Memory | 1 GB | 512 MB | 512 MB | 256 MB | 256 MB |
| Form Factor | Rack-mount | Rack-mount | Rack-mount | Rack-mount | Rack-mount |
| Height | N/A | 1.75 inches | N/A | 1.75 inches | N/A |
| High Availability Support | Supported | Supported | Supported | Not Supported | Supported |
| Integrated Services | Voice, Video, WAN Optimization | Voice / Video / WAN Optimization | Voice / Video / WAN Optimization | Voice / Video / WAN Optimization | Voice / Video / WAN Optimization |
| Interface Ports | RJ-45, SFP | RJ-45 | RJ-45 / SFP | RJ-45, SFP | RJ-45 / SFP |
| LAN Ports | 2 LAN Ports | Modular LAN | 4 LAN Ports | 4 LAN Ports | Modular LAN |
| Management | Managed | Managed | Managed | Managed | Managed |
| Memory | 2 GB | 4 GB | 4 GB | 1 GB | 4 GB |
| Modular Slots Available | 1 Slot | 2 Slots | 3+ Slots | 1 Slot | 2 Slots |
| Network Protocols | IPv4, IPv6 | IPv4, IPv6 | IPv4, IPv6, MPLS | IPv4, IPv6, MPLS | IPv4 / IPv6 |
| Power | 75W | 130 W | 150 W | 70 Watt | 115W |
| Power Source | AC Power Supply / DC Power Supply (Redundant) | AC Power Supply / Redundant | AC Power Supply / DC Power Supply / Redundant | AC Power Supply | AC Power Supply / Redundant |
| Product Name | Cisco ISR4321-SEC/K9 | Cisco ISR 4331 Secure Integrated Services Router | ISR4431-DNA | Cisco ISR 4221 Integrated Services Router | Cisco ISR4351-DNA |
| Product Type | Enterprise Router | Enterprise Router | Enterprise Router | Enterprise Router | Enterprise Router |
| QoS Features | Supported | Supported | Supported | Supported | Supported |
| Remote Management | SSH, Telnet, SNMP | SSH, Telnet, SNMP | SSH / Telnet / SNMP / NETCONF | SSH, Telnet, SNMP | CLI / SNMP / Cisco DNA Center |
| Routing Protocols | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / MPLS / IS-IS / RIP / Static Routing | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / RIP / Static Routing |
| Safety | N/A | N/A | N/A | N/A | N/A |
| Speed/Capacity | Gigabit | Gigabit | Gigabit | Gigabit | Gigabit |
| Stacking Capability | No | No | No | No | No |
| Telecom | N/A | N/A | N/A | N/A | N/A |
| Throughput Capacity | 300 Mbps | 0.1 Gbps | 1.2 Gbps | 0.25 Gbps | 1 Gbps |
| Use Case | Enterprise, Small Business | Enterprise | Enterprise | Enterprise / Branch Office | Enterprise |
| VPN Support | IPSec / SSL VPN / DMVPN / FlexVPN | IPSec / SSL VPN / DMVPN / FlexVPN | IPSec / SSL VPN / GRE / DMVPN / FlexVPN | IPSec / SSL VPN | IPSec / SSL VPN / DMVPN / FlexVPN / N/A |
| WAN Configuration | Dual WAN | Dual WAN | Dual WAN | Dual WAN | Dual WAN |
| WAN Ports | 2 WAN Ports | Modular WAN | Modular WAN | 2 WAN | Modular WAN |
| Weight | N/A | 11 lbs | N/A | 10 lbs | N/A |
| Wi-Fi Standard | N/A | N/A | N/A | N/A | N/A |
| Width | N/A | 17.5 inches | N/A | 17.6 inches | N/A |
| Wireless Support | No | No | No | No | No |
Showing - of 0 Results
Questions & Answers
Q
What is the Cisco ISR 4221 AX Bundle w/APP, SEC lic?
A
The Cisco ISR 4221 AX Bundle w/APP, SEC lic (SKU ISR4221-AX/K9) is a fixed-port integrated services router with Cisco IOS XE, application-hosting capabilities, and an advanced Security license for firewall, IPS, AMP, URL filtering, and VPN encryption.
Q
What hardware specifications does the ISR 4221 AX include?
A
The ISR 4221 AX features two Gigabit Ethernet ports, USB and console ports, 4 GB DRAM, 4 GB flash memory, an integrated Application Hosting module, and supports up to 50 Mbps aggregated WAN throughput in a compact desktop or rack-mountable design.
Q
What throughput and performance can I expect?
A
With the AX Bundle and SEC license enabled, the ISR 4221 delivers up to 50 Mbps of aggregate WAN throughput, hardware-accelerated AES-256 encryption, and consistent performance under full security-service load.
Q
Which security features are provided by the SEC license?
A
The Security (SEC) license includes Cisco IOS XE Firewall, Next-Generation Intrusion Prevention (NGIPS), Advanced Malware Protection (AMP), URL Filtering, and site-to-site IPsec VPN with AES-256 encryption.
Q
Can I host custom applications on this router?
A
Yes. The integrated Application Hosting (APP) module supports Docker containers and custom Linux-based applications, enabling local processing, analytics, and edge-services deployment.
Q
Does the Cisco ISR 4221 AX support SD-WAN?
A
Yes. The ISR 4221 AX running IOS XE is fully SD-WAN ready and can be managed via Cisco SD-WAN vManage for centralized policy enforcement, path control, and telemetry.
Q
Which software platform runs on the ISR 4221 AX?
A
Cisco IOS XE powers the ISR 4221 AX, offering modular services, programmability via RESTCONF/NETCONF, and integration with Cisco DNA Center for automated provisioning and policy management.
Q
How do I configure VPN services on the ISR 4221 AX?
A
You can configure site-to-site IPsec VPN and AnyConnect SSL VPN via CLI templates, Cisco Configuration Professional, or Cisco DNA Center, leveraging hardware crypto acceleration for high performance.
Q
What management and orchestration tools are supported?
A
The ISR 4221 AX is supported by Cisco DNA Center, Cisco Prime Infrastructure, Cisco SD-WAN vManage, and open APIs (RESTCONF/NETCONF) for full life-cycle management and telemetry.
Q
Is the security license subscription-based or perpetual?
A
You can purchase the SEC license as a perpetual Cisco IOS XE license (K9) or as a subscription under Cisco Smart Licensing, providing flexible renewal and compliance tracking.
Q
What deployment scenarios suit the ISR 4221 AX?
A
The ISR 4221 AX is ideal for small to medium branch offices, retail outlets, and remote or micro-branch sites that require secure WAN connectivity with local application hosting.
Q
Can I upgrade the router’s throughput or features later?
A
Yes. You can upgrade DRAM and flash, activate additional IOS XE feature licenses, or add security subscriptions to scale performance and service capabilities as your network grows.
Q
What are the power and environmental specs?
A
The ISR 4221 AX supports 12–24 V DC or 100–240 V AC input, consumes up to 40 W, and operates between 0 °C and 40 °C in desktop or 1U rack-mount form factor.
Q
What warranty and support options are available?
A
Cisco provides a 90-day limited hardware warranty by default. For enhanced SLA, access to software updates, and 24/7 technical assistance, you can purchase Cisco SMARTnet service.
Q
How do I order the Cisco ISR 4221 AX Bundle w/APP, SEC lic?
A
Order SKU ISR4221-AX/K9 through Cisco authorized resellers, distributors, or Cisco’s online portal. Contact your Cisco partner for pricing, lead times, and configuration guidance.
Q
Does the ISR 4221 AX support cloud connectivity?
A
Yes. The ISR 4221 AX supports secure connectivity to AWS, Microsoft Azure, and Google Cloud via VPN or Cisco Cloud OnRamp for SaaS, enabling optimized cloud access.
Q
How can I ensure optimal performance on my ISR 4221 AX?
A
Keep IOS XE up to date, enable hardware offload for encryption, right-size security profiles, and implement QoS policies to prioritize critical applications and maintain consistent throughput.