United States$5,000,000+
Inventory Delivered By
K
Kevin Marshall
5
DNA subscription adds great visibility. Router performance has been solid.
ISR4321-DNA
Original Stock
Ready to Ship
Cisco ISR 4321 (2GE,2NIM,4G FLASH,4G DRAM,IPB) with DNA sub
FEATURED DEAL
Name:
ISR4321-DNA
- Description:
- Cisco ISR 4321 (2GE,2NIM,4G FLASH,4G DRAM,IPB) with DNA sub
- Rating:
Added to cart 28 times recently
- Availability:
In stock - Ready to Ship
- Brand:
- Cisco
- GTIN:
- 430816355740
- Condition:
- Warranty:
- 3
- List Price:
$2,871.99
- Price:
$2,154.0025% off
Quantity:
1
Business price:
3 Year Extended Warranty
Same-day Shipping
14-Day Money Back Guarantee
Shipping:
Payment:
3 Year Extended Warranty
Same-day Shipping
14-Day Money Back Guarantee
Need Additional Discount on Product?
Request a quote below - Get Exclusive Pricing and Support.
Shipping:
Payment:
TRUSTED, TRIED, PROVEN
Officially Accredited
& Verified By
Next-Gen IT
Solutions Powered By
ISR4321-DNA Overview
ISR4321-DNA is a fixed enterprise router designed with dual WAN configuration and robust power options provided by an AC power supply, featuring 2 WAN ports and 4 LAN ports that support 10/100/1000 Ethernet technology. It is built to deliver integrated services for voice and video while offering modular expansion capabilities and a secure, high-performance platform for business connectivity.
ISR4321-DNA also supports advanced VPN features including IPSec, SSL VPN, DMVPN, and FlexVPN to safeguard network communications. With a throughput capacity of 0.3 Gbps, redundant high availability support, and management via Cisco DNA Center, CLI, and Web UI, it is ideally suited for enterprise and business use cases requiring reliable routing, firewall security, and comprehensive network services.
ISR4321-DNA price is $2,154.00, a 25% saving from the Cisco list price of $2,871.99. ISR4321-DNA is in stock and available for next-day dispatch. (terms applied)
Request bulk order quote for ISR4321-DNA for additional pricing. Browse the full Router Isr 4000 series or explore all Cisco products.
ISR4321-DNA Specifications
- Power Source
- AC Power Supply
- Form Factor
- Rack-mount
- Ethernet Technology
- 10/100/1000
- Height
- 1.75 inches
- Weight
- 11 lbs
- Memory
- 4 GB
- Depth
- 15 inches
- Width
- 17 inches
- Flash Memory
- 512 MB
- Product Type
- Enterprise Router
- Routing Protocols
- OSPF / BGP / EIGRP / RIP / Static Routing
- Architecture
- Fixed
- WAN Configuration
- Dual WAN
- WAN Ports
- 2 WAN
- Wi-Fi Standard
- N/A
- Connectivity Type
- Wired
- Compliance Standards
- FCC, CE
- Wireless Support
- No
- Firewall Features
- Yes
- Management
- Managed
- Safety
- N/A
- EMC
- N/A
- Telecom
- N/A
- QoS Features
- Supported
- Stacking Capability
- No
- 5G Support
- No
- Device Type
- Router
- Network Protocols
- IPv4, IPv6
- High Availability Support
- Supported
- Expansion Slots
- EHWIC
- Broadband
- N/A
- Integrated Services
- Voice / Video
- LAN Ports
- 4 LAN Ports
- Use Case
- Enterprise / Business
- Built-in Security Features
- Firewall / Intrusion Prevention / Malware Protection
- Speed/Capacity
- Gigabit
- Modular Slots Available
- 3+ Slots
- Interface Ports
- RJ-45 / SFP
- Features
- VPN / IPv6 Compatible / Firewall / MPLS
- Throughput Capacity
- 0.3 Gbps
- VPN Support
- IPSec / SSL VPN / DMVPN / FlexVPN / N/A
- Remote Management
- Cisco DNA Center, CLI, Web UI
- Power
- 200 Watts
- Product Name
- ISR4321-DNA
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table 
| ISR4321-DNA |  ISR4331-V/K9 |  ISR4461-VSEC/K9 |  ISR4351-AX/K9 |  ISR4321-V/K9 | |
|---|---|---|---|---|---|
| 5G Support | No | No | No | No | No |
| Architecture | Fixed | Modular | Modular | Fixed | Fixed |
| Broadband | N/A | N/A | N/A | N/A | N/A |
| Built-in Security Features | Firewall / Intrusion Prevention / Malware Protection | Firewall / Intrusion Prevention / Malware Protection | Firewall / Intrusion Prevention / Malware Protection | Firewall / Intrusion Prevention | Firewall / Intrusion Prevention |
| Compliance Standards | FCC, CE | CE / FCC / UL | FCC, CE, RoHS | FCC / CE / RoHS | FCC, CE |
| Connectivity Type | Wired | Wired | Wired | Wired | Wired / Ethernet |
| Depth | 15 inches | 13.9 inches | 18.3 inches | 16.9 inches | 16.1 inches |
| Device Type | Router | Router | Router | Router | Router |
| EMC | N/A | N/A | N/A | N/A | N/A |
| Ethernet Technology | 10/100/1000 | 10/100/1000 | 10/100/1000 | 10/100/1000 | 10/100/1000 |
| Expansion Slots | EHWIC | EHWIC / NIM / SM-X | EHWIC | NIM | EHWIC |
| Features | VPN / IPv6 Compatible / Firewall / MPLS | VPN / Voice / Video / IPv6 Compatible / Firewall / MPLS | VPN / VoIP / IPv6 Compatible / Firewall / MPLS | VPN / VoIP / IPv6 Compatible / Firewall / WAN Optimization | VPN / VoIP / IPv6 Compatible / Firewall / MPLS |
| Firewall Features | Yes | Yes | Yes | Yes | Yes |
| Flash Memory | 512 MB | 2 GB | 2 GB | 256 MB | 256 MB |
| Form Factor | Rack-mount | Rack-mount | Rack-mount | Rack-mount | Rack-mount |
| Height | 1.75 inches | 4.33 inches | 1.75 inches | 1.7 inches | 1.75 inches |
| High Availability Support | Supported | Supported | Supported | Supported | Supported |
| Integrated Services | Voice / Video | Voice / Video / WAN Optimization | Voice / Video / WAN Optimization | Voice / Video / WAN Optimization | Voice / Video |
| Interface Ports | RJ-45 / SFP | RJ-45 / SFP | RJ-45 / SFP | RJ-45 | RJ-45 |
| LAN Ports | 4 LAN Ports | 4 LAN Ports | 4 LAN Ports | 4 LAN Ports | 4 LAN Ports |
| Management | Managed | Managed | Managed | Managed | Managed |
| Memory | 4 GB | 4 GB | 4 GB | 1 GB | 2 GB |
| Modular Slots Available | 3+ Slots | 3+ Slots | 2 Slots | 2 Slots | 2 Slots |
| Network Protocols | IPv4, IPv6 | IPv4 / IPv6 / MPLS | IPv4, IPv6, MPLS | IPv4 / IPv6 / MPLS / VPN | IPv4, IPv6 |
| Power | 200 Watts | 250 W | 305 W | 62 W | 65W |
| Power Source | AC Power Supply | AC Power Supply / Redundant | AC Power Supply / Redundant | AC Power Supply / DC Power Supply / Redundant | AC Power Supply / Redundant |
| Product Name | ISR4321-DNA | Cisco ISR 4331 Integrated Services Router | Cisco ISR 4461 Integrated Services Router - Security Enhanced | Cisco ISR4351-AX/K9 Integrated Services Router | Cisco ISR4321 Integrated Services Router |
| Product Type | Enterprise Router | Enterprise Router | Enterprise Router | Enterprise Router | Enterprise Router |
| QoS Features | Supported | Supported | Supported | Supported | Supported |
| Remote Management | Cisco DNA Center, CLI, Web UI | SSH / Telnet / SNMP | SSH, Telnet, SNMP, NetConf | SSH / Telnet / SNMP | SSH, Telnet, SNMP |
| Routing Protocols | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / MPLS / IS-IS / RIP / Static Routing | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / MPLS / IS-IS / RIP / Static Routing |
| Safety | N/A | N/A | N/A | N/A | N/A |
| Speed/Capacity | Gigabit | Gigabit | Gigabit | Gigabit | Gigabit |
| Stacking Capability | No | Yes | No | No | No |
| Telecom | N/A | N/A | N/A | N/A | N/A |
| Throughput Capacity | 0.3 Gbps | 0.15 Gbps | 1 Gbps | 0.15 Gbps | 300 Mbps |
| Use Case | Enterprise / Business | Enterprise / Branch | Enterprise | Enterprise | Enterprise |
| VPN Support | IPSec / SSL VPN / DMVPN / FlexVPN / N/A | IPSec / SSL VPN / DMVPN / FlexVPN / N/A | IPSec / SSL VPN / GRE / DMVPN / FlexVPN | IPSec / SSL VPN / DMVPN / FlexVPN | IPSec / SSL VPN / DMVPN / FlexVPN |
| WAN Configuration | Dual WAN | Dual WAN | Dual WAN | WAN | Dual WAN |
| WAN Ports | 2 WAN | 2 WAN | 2 WAN | 2 WAN | 2 WAN |
| Weight | 11 lbs | 19 lbs | 27 lbs | 19 lbs | 12.3 lbs |
| Wi-Fi Standard | N/A | N/A | N/A | N/A | N/A |
| Width | 17 inches | 17.4 inches | 17.5 inches | 17.3 inches | 17.3 inches |
| Wireless Support | No | No | No | No | No |
Reviews & Ratings
R
Ryan Whitfield
4
Good routing performance with modern management features.
S
Scott Bennett
4
Cisco DNA simplifies operations for branch networks.
O
Oliver Grant
5
Stable ISR with added value from DNA licensing.
D
Derek Lawson
4
Ideal for teams adopting software driven networking.
Questions & Answers
What is the Cisco ISR 4321 with DNA subscription?
The Cisco ISR 4321 with DNA subscription is a modular branch router featuring 2 Gigabit Ethernet ports, 2 Network Interface Module (NIM) slots, 4 GB flash, 4 GB DRAM, IP Base license, and Cisco DNA software assurance for advanced network automation and security.
Which performance capabilities does the ISR 4321 deliver?
The ISR 4321 delivers up to 50 Mbps of performance with hardware acceleration, support for multiple WAN links, and QoS to ensure reliable application delivery in small to midsize branch environments.
What network modules are supported on the ISR 4321?
The ISR 4321 supports two NIM slots compatible with Ethernet, serial, DSL, and other WAN interface modules for flexible connectivity and network expansion.
How much memory and storage does the ISR 4321 include?
The device includes 4 GB of onboard DRAM and 4 GB of onboard flash storage to accommodate IOS XE software, configurations, logs, and optional feature images.
What is included in the Cisco DNA subscription for ISR 4321?
Cisco DNA subscription provides continuous feature updates, automation, analytics, security intelligence, and centralized management through Cisco DNA Center for the ISR 4321.
How does the ISR 4321 enhance network security?
The ISR 4321 integrates Cisco Secure Firewall features, intrusion prevention, URL filtering, and encryption to deliver comprehensive threat defense at the branch.
What are the typical use cases for the Cisco ISR 4321?
The ISR 4321 is ideal for small to midsize branch offices, retail locations, and remote sites requiring secure WAN connectivity, basic routing, and on-premises application access.
What port options are available on the Cisco ISR 4321?
The router offers 2 fixed Gigabit Ethernet ports, 2 NIM slots for additional WAN or LAN interfaces, and an optional Network Interface Card for further expansion.
How can I manage the ISR 4321?
You can manage the ISR 4321 using Cisco DNA Center, Cisco IOS XE CLI, web-based device manager, or industry-standard network management tools via SNMP and REST APIs.
Is the ISR 4321 suitable for SD-WAN deployments?
Yes, the ISR 4321 supports Cisco SD-WAN software, enabling secure, policy-based overlay connectivity across diverse transport links.
What is the power consumption of the Cisco ISR 4321?
Typical power consumption is approximately 25 W under full load, with support for AC power input and optional DC power modules.
How do I configure network interface modules on the ISR 4321?
Insert the compatible NIM, enable it via Cisco IOS XE CLI with the 'platform hardware slot' commands, and configure interface parameters under global configuration mode.
What warranty options are available for the ISR 4321?
Cisco offers a 1-year limited hardware warranty with next-business-day replacement, extendable via Cisco SMARTnet service for 24/7 technical support and expedited hardware replacement.
How scalable is the Cisco ISR 4321?
With modular NIM slots and integrated expansion capabilities, the ISR 4321 scales from basic branch routing to advanced services like security, WAN optimization, and unified communications.
Can the ISR 4321 support virtualization services?
Yes, the ISR 4321 supports Cisco IOS XE virtualization for network services, allowing multiple virtual network functions (VNFs) to run on a single platform.
How does the ISR 4321 compare to the ISR 4331?
The ISR 4321 offers lower performance (up to 50 Mbps) and fewer expansion slots than the ISR 4331 (up to 100 Mbps), making it more cost-effective for smaller branch deployments.
What support and maintenance services are available for the ISR 4321?
Customers can choose Cisco SMARTnet or Cisco Software Support Service for 24/7 technical assistance, software updates, hardware replacement, and proactive diagnostic tools.