Featured Deal
Hand-picked by our procurement team for standout value. This unit is offered at our sharpest price on current stock, verified against live market rates.
Name:
Added to cart 28 times recently
Ready to Ship
Certified Refurbished
Professionally inspected, bench-tested, and firmware-verified, with configurations wiped. Restored to full working order and backed by our warranty.
$2,871.99
$2,154.0025% off
Quantity:
3 Year Extended Warranty
Same-day Shipping
30-Day Money Back Guarantee
Shipping:
Payment:
3 Year Extended Warranty
Same-day Shipping
30-Day Money Back Guarantee
Need Additional Discount on Product?
Request a quote below - Get Exclusive Pricing and Support.
Shipping:
Payment:
ISR4321-DNA
Cisco ISR 4321 (2GE,2NIM,4G FLASH,4G DRAM,IPB) with DNA sub
Trusted by the Highest-Stakes Buyers
Federal agencies and Fortune 500 operations source through ORM Systems.
US Government & Defense
Enterprise Clients
Built Global. Stocked Local.
Regional teams and 25+ distribution partners keep stock near you and accountability in your time zone.
Buyer Protection on Every Order
Pay by PayPal or Revolut with full chargeback rights. Order on PO terms, Net-30 for government.
Verified By Federal Bodies
Every registration we claim is public record — check our federal contractor status yourself before you spend a dollar.
Since 2016, Enterprise-Trusted
Ten years serving buyers who audit their vendors. From federal agencies to 20,000+ enterprise clients worldwide.
ISR4321-DNA is a fixed enterprise router designed with dual WAN configuration and robust power options provided by an AC power supply, featuring 2 WAN ports and 4 LAN ports that support 10/100/1000 Ethernet technology. It is built to deliver integrated services for voice and video while offering modular expansion capabilities and a secure, high-performance platform for business connectivity.
ISR4321-DNA also supports advanced VPN features including IPSec, SSL VPN, DMVPN, and FlexVPN to safeguard network communications. With a throughput capacity of 0.3 Gbps, redundant high availability support, and management via Cisco DNA Center, CLI, and Web UI, it is ideally suited for enterprise and business use cases requiring reliable routing, firewall security, and comprehensive network services.
ISR4321-DNA price is $2,154.00, a 25% saving from the Cisco list price of $2,871.99. ISR4321-DNA is in stock and available for next-day dispatch. (terms applied)
Request bulk order quote for ISR4321-DNA for additional pricing. Browse the full Router Isr 4000 series or explore all Cisco products.
Mon–Fri: [09:00-16:00]
Avg. response under 30 mins
| ISR4321-DNA |  ISR4331-V/K9 |  ISR4461-VSEC/K9 |  ISR4351-AX/K9 |  ISR4321-V/K9 | |
|---|---|---|---|---|---|
| 5G Support | No | No | No | No | No |
| Architecture | Fixed | Modular | Modular | Fixed | Fixed |
| Built-in Security Features | Firewall / Intrusion Prevention / Malware Protection | Firewall / Intrusion Prevention / Malware Protection | Firewall / Intrusion Prevention / Malware Protection | Firewall / Intrusion Prevention | Firewall / Intrusion Prevention |
| Compliance Standards | FCC, CE | CE / FCC / UL | FCC, CE, RoHS | FCC / CE / RoHS | FCC, CE |
| Connectivity Type | Wired | Wired | Wired | Wired | Wired / Ethernet |
| Depth | 15 inches | 13.9 inches | 18.3 inches | 16.9 inches | 16.1 inches |
| Device Type | Router | Router | Router | Router | Router |
| Ethernet Technology | 10/100/1000 | 10/100/1000 | 10/100/1000 | 10/100/1000 | 10/100/1000 |
| Expansion Slots | EHWIC | EHWIC / NIM / SM-X | EHWIC | NIM | EHWIC |
| Features | VPN / IPv6 Compatible / Firewall / MPLS | VPN / Voice / Video / IPv6 Compatible / Firewall / MPLS | VPN / VoIP / IPv6 Compatible / Firewall / MPLS | VPN / VoIP / IPv6 Compatible / Firewall / WAN Optimization | VPN / VoIP / IPv6 Compatible / Firewall / MPLS |
| Firewall Features | Yes | Yes | Yes | Yes | Yes |
| Flash Memory | 512 MB | 2 GB | 2 GB | 256 MB | 256 MB |
| Form Factor | Rack-mount | Rack-mount | Rack-mount | Rack-mount | Rack-mount |
| Height | 1.75 inches | 4.33 inches | 1.75 inches | 1.7 inches | 1.75 inches |
| High Availability Support | Supported | Supported | Supported | Supported | Supported |
| Integrated Services | Voice / Video | Voice / Video / WAN Optimization | Voice / Video / WAN Optimization | Voice / Video / WAN Optimization | Voice / Video |
| Interface Ports | RJ-45 / SFP | RJ-45 / SFP | RJ-45 / SFP | RJ-45 | RJ-45 |
| LAN Ports | 4 LAN Ports | 4 LAN Ports | 4 LAN Ports | 4 LAN Ports | 4 LAN Ports |
| Management | Managed | Managed | Managed | Managed | Managed |
| Memory | 4 GB | 4 GB | 4 GB | 1 GB | 2 GB |
| Modular Slots Available | 3+ Slots | 3+ Slots | 2 Slots | 2 Slots | 2 Slots |
| Network Protocols | IPv4, IPv6 | IPv4 / IPv6 / MPLS | IPv4, IPv6, MPLS | IPv4 / IPv6 / MPLS / VPN | IPv4, IPv6 |
| Power | 200 Watts | 250 W | 305 W | 62 W | 65W |
| Power Source | AC Power Supply | AC Power Supply / Redundant | AC Power Supply / Redundant | AC Power Supply / DC Power Supply / Redundant | AC Power Supply / Redundant |
| Product Name | ISR4321-DNA | Cisco ISR 4331 Integrated Services Router | Cisco ISR 4461 Integrated Services Router - Security Enhanced | Cisco ISR4351-AX/K9 Integrated Services Router | Cisco ISR4321 Integrated Services Router |
| Product Type | Enterprise Router | Enterprise Router | Enterprise Router | Enterprise Router | Enterprise Router |
| QoS Features | Supported | Supported | Supported | Supported | Supported |
| Remote Management | Cisco DNA Center, CLI, Web UI | SSH / Telnet / SNMP | SSH, Telnet, SNMP, NetConf | SSH / Telnet / SNMP | SSH, Telnet, SNMP |
| Routing Protocols | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / MPLS / IS-IS / RIP / Static Routing | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / MPLS / IS-IS / RIP / Static Routing |
| Speed/Capacity | Gigabit | Gigabit | Gigabit | Gigabit | Gigabit |
| Stacking Capability | No | Yes | No | No | No |
| Throughput Capacity | 0.3 Gbps | 0.15 Gbps | 1 Gbps | 0.15 Gbps | 300 Mbps |
| Use Case | Enterprise / Business | Enterprise / Branch | Enterprise | Enterprise | Enterprise |
| VPN Support | IPSec / SSL VPN / DMVPN / FlexVPN / N/A | IPSec / SSL VPN / DMVPN / FlexVPN / N/A | IPSec / SSL VPN / GRE / DMVPN / FlexVPN | IPSec / SSL VPN / DMVPN / FlexVPN | IPSec / SSL VPN / DMVPN / FlexVPN |
| WAN Configuration | Dual WAN | Dual WAN | Dual WAN | WAN | Dual WAN |
| WAN Ports | 2 WAN | 2 WAN | 2 WAN | 2 WAN | 2 WAN |
| Weight | 11 lbs | 19 lbs | 27 lbs | 19 lbs | 12.3 lbs |
| Width | 17 inches | 17.4 inches | 17.5 inches | 17.3 inches | 17.3 inches |
| Wireless Support | No | No | No | No | No |
Every unit is authentic, sourced through trusted and authorised channels, and serial-verified on request. Genuine networking and IT hardware, guaranteed, or your money back.
New products are backed by up to 3 years of extended warranty, and certified refurbished units by up to 3 months, for dependable protection on every order. Coverage is clear, honoured in full, and confirmed on each product page.
If a unit ever falls short, our streamlined RMA process gets a replacement to you fast, with advance replacement available to keep your network running. No jargon, no runaround.
Every device is inspected, bench-tested, and firmware-verified, with configurations wiped before dispatch. Additional testing can be arranged to confirm full working condition on request.
Our specialists assist with compatibility, configuration, licensing, and installation, before and after you buy. Real hardware expertise, whenever you need it.
dispatched quickly and shipped worldwide from regional hubs, fully tracked and insured.
DNA subscription adds great visibility. Router performance has been solid.
Good routing performance with modern management features.
Cisco DNA simplifies operations for branch networks.
Stable ISR with added value from DNA licensing.
Ideal for teams adopting software driven networking.
The Cisco ISR 4321 with DNA subscription is a modular branch router featuring 2 Gigabit Ethernet ports, 2 Network Interface Module (NIM) slots, 4 GB flash, 4 GB DRAM, IP Base license, and Cisco DNA software assurance for advanced network automation and security.
The ISR 4321 delivers up to 50 Mbps of performance with hardware acceleration, support for multiple WAN links, and QoS to ensure reliable application delivery in small to midsize branch environments.
The ISR 4321 supports two NIM slots compatible with Ethernet, serial, DSL, and other WAN interface modules for flexible connectivity and network expansion.
The device includes 4 GB of onboard DRAM and 4 GB of onboard flash storage to accommodate IOS XE software, configurations, logs, and optional feature images.
Cisco DNA subscription provides continuous feature updates, automation, analytics, security intelligence, and centralized management through Cisco DNA Center for the ISR 4321.
The ISR 4321 integrates Cisco Secure Firewall features, intrusion prevention, URL filtering, and encryption to deliver comprehensive threat defense at the branch.
The ISR 4321 is ideal for small to midsize branch offices, retail locations, and remote sites requiring secure WAN connectivity, basic routing, and on-premises application access.
The router offers 2 fixed Gigabit Ethernet ports, 2 NIM slots for additional WAN or LAN interfaces, and an optional Network Interface Card for further expansion.
You can manage the ISR 4321 using Cisco DNA Center, Cisco IOS XE CLI, web-based device manager, or industry-standard network management tools via SNMP and REST APIs.
Yes, the ISR 4321 supports Cisco SD-WAN software, enabling secure, policy-based overlay connectivity across diverse transport links.
Typical power consumption is approximately 25 W under full load, with support for AC power input and optional DC power modules.
Insert the compatible NIM, enable it via Cisco IOS XE CLI with the 'platform hardware slot' commands, and configure interface parameters under global configuration mode.
Cisco offers a 1-year limited hardware warranty with next-business-day replacement, extendable via Cisco SMARTnet service for 24/7 technical support and expedited hardware replacement.
With modular NIM slots and integrated expansion capabilities, the ISR 4321 scales from basic branch routing to advanced services like security, WAN optimization, and unified communications.
Yes, the ISR 4321 supports Cisco IOS XE virtualization for network services, allowing multiple virtual network functions (VNFs) to run on a single platform.
The ISR 4321 offers lower performance (up to 50 Mbps) and fewer expansion slots than the ISR 4331 (up to 100 Mbps), making it more cost-effective for smaller branch deployments.
Customers can choose Cisco SMARTnet or Cisco Software Support Service for 24/7 technical assistance, software updates, hardware replacement, and proactive diagnostic tools.
United States
