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ISR4321-DNA
Cisco ISR 4321 (2GE,2NIM,4G FLASH,4G DRAM,IPB) with DNA sub
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ISR4321-DNA is a fixed enterprise router designed with dual WAN configuration and robust power options provided by an AC power supply, featuring 2 WAN ports and 4 LAN ports that support 10/100/1000 Ethernet technology. It is built to deliver integrated services for voice and video while offering modular expansion capabilities and a secure, high-performance platform for business connectivity.
ISR4321-DNA also supports advanced VPN features including IPSec, SSL VPN, DMVPN, and FlexVPN to safeguard network communications. With a throughput capacity of 0.3 Gbps, redundant high availability support, and management via Cisco DNA Center, CLI, and Web UI, it is ideally suited for enterprise and business use cases requiring reliable routing, firewall security, and comprehensive network services.
ISR4321-DNA price is $2,154.00, a 25% saving from the Cisco list price of $2,871.99. ISR4321-DNA is in stock and available for next-day dispatch. (terms applied)
Request bulk order quote for ISR4321-DNA for additional pricing. Browse the full Router Isr 4000 series or explore all Cisco products.
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| 5G Support | No | No | No | No | No |
| Architecture | Fixed | Modular | Modular | Fixed | Fixed |
| Broadband | N/A | N/A | N/A | N/A | N/A |
| Built-in Security Features | Firewall / Intrusion Prevention / Malware Protection | Firewall / Intrusion Prevention / Malware Protection | Firewall / Intrusion Prevention / Malware Protection | Firewall / Intrusion Prevention | Firewall / Intrusion Prevention |
| Compliance Standards | FCC, CE | CE / FCC / UL | FCC, CE, RoHS | FCC / CE / RoHS | FCC, CE |
| Connectivity Type | Wired | Wired | Wired | Wired | Wired / Ethernet |
| Depth | 15 inches | 13.9 inches | 18.3 inches | 16.9 inches | 16.1 inches |
| Device Type | Router | Router | Router | Router | Router |
| EMC | N/A | N/A | N/A | N/A | N/A |
| Ethernet Technology | 10/100/1000 | 10/100/1000 | 10/100/1000 | 10/100/1000 | 10/100/1000 |
| Expansion Slots | EHWIC | EHWIC / NIM / SM-X | EHWIC | NIM | EHWIC |
| Features | VPN / IPv6 Compatible / Firewall / MPLS | VPN / Voice / Video / IPv6 Compatible / Firewall / MPLS | VPN / VoIP / IPv6 Compatible / Firewall / MPLS | VPN / VoIP / IPv6 Compatible / Firewall / WAN Optimization | VPN / VoIP / IPv6 Compatible / Firewall / MPLS |
| Firewall Features | Yes | Yes | Yes | Yes | Yes |
| Flash Memory | 512 MB | 2 GB | 2 GB | 256 MB | 256 MB |
| Form Factor | Rack-mount | Rack-mount | Rack-mount | Rack-mount | Rack-mount |
| Height | 1.75 inches | 4.33 inches | 1.75 inches | 1.7 inches | 1.75 inches |
| High Availability Support | Supported | Supported | Supported | Supported | Supported |
| Integrated Services | Voice / Video | Voice / Video / WAN Optimization | Voice / Video / WAN Optimization | Voice / Video / WAN Optimization | Voice / Video |
| Interface Ports | RJ-45 / SFP | RJ-45 / SFP | RJ-45 / SFP | RJ-45 | RJ-45 |
| LAN Ports | 4 LAN Ports | 4 LAN Ports | 4 LAN Ports | 4 LAN Ports | 4 LAN Ports |
| Management | Managed | Managed | Managed | Managed | Managed |
| Memory | 4 GB | 4 GB | 4 GB | 1 GB | 2 GB |
| Modular Slots Available | 3+ Slots | 3+ Slots | 2 Slots | 2 Slots | 2 Slots |
| Network Protocols | IPv4, IPv6 | IPv4 / IPv6 / MPLS | IPv4, IPv6, MPLS | IPv4 / IPv6 / MPLS / VPN | IPv4, IPv6 |
| Power | 200 Watts | 250 W | 305 W | 62 W | 65W |
| Power Source | AC Power Supply | AC Power Supply / Redundant | AC Power Supply / Redundant | AC Power Supply / DC Power Supply / Redundant | AC Power Supply / Redundant |
| Product Name | ISR4321-DNA | Cisco ISR 4331 Integrated Services Router | Cisco ISR 4461 Integrated Services Router - Security Enhanced | Cisco ISR4351-AX/K9 Integrated Services Router | Cisco ISR4321 Integrated Services Router |
| Product Type | Enterprise Router | Enterprise Router | Enterprise Router | Enterprise Router | Enterprise Router |
| QoS Features | Supported | Supported | Supported | Supported | Supported |
| Remote Management | Cisco DNA Center, CLI, Web UI | SSH / Telnet / SNMP | SSH, Telnet, SNMP, NetConf | SSH / Telnet / SNMP | SSH, Telnet, SNMP |
| Routing Protocols | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / MPLS / IS-IS / RIP / Static Routing | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / MPLS / IS-IS / RIP / Static Routing |
| Safety | N/A | N/A | N/A | N/A | N/A |
| Speed/Capacity | Gigabit | Gigabit | Gigabit | Gigabit | Gigabit |
| Stacking Capability | No | Yes | No | No | No |
| Telecom | N/A | N/A | N/A | N/A | N/A |
| Throughput Capacity | 0.3 Gbps | 0.15 Gbps | 1 Gbps | 0.15 Gbps | 300 Mbps |
| Use Case | Enterprise / Business | Enterprise / Branch | Enterprise | Enterprise | Enterprise |
| VPN Support | IPSec / SSL VPN / DMVPN / FlexVPN / N/A | IPSec / SSL VPN / DMVPN / FlexVPN / N/A | IPSec / SSL VPN / GRE / DMVPN / FlexVPN | IPSec / SSL VPN / DMVPN / FlexVPN | IPSec / SSL VPN / DMVPN / FlexVPN |
| WAN Configuration | Dual WAN | Dual WAN | Dual WAN | WAN | Dual WAN |
| WAN Ports | 2 WAN | 2 WAN | 2 WAN | 2 WAN | 2 WAN |
| Weight | 11 lbs | 19 lbs | 27 lbs | 19 lbs | 12.3 lbs |
| Wi-Fi Standard | N/A | N/A | N/A | N/A | N/A |
| Width | 17 inches | 17.4 inches | 17.5 inches | 17.3 inches | 17.3 inches |
| Wireless Support | No | No | No | No | No |
DNA subscription adds great visibility. Router performance has been solid.
Good routing performance with modern management features.
Cisco DNA simplifies operations for branch networks.
Stable ISR with added value from DNA licensing.
Ideal for teams adopting software driven networking.
The Cisco ISR 4321 with DNA subscription is a modular branch router featuring 2 Gigabit Ethernet ports, 2 Network Interface Module (NIM) slots, 4 GB flash, 4 GB DRAM, IP Base license, and Cisco DNA software assurance for advanced network automation and security.
The ISR 4321 delivers up to 50 Mbps of performance with hardware acceleration, support for multiple WAN links, and QoS to ensure reliable application delivery in small to midsize branch environments.
The ISR 4321 supports two NIM slots compatible with Ethernet, serial, DSL, and other WAN interface modules for flexible connectivity and network expansion.
The device includes 4 GB of onboard DRAM and 4 GB of onboard flash storage to accommodate IOS XE software, configurations, logs, and optional feature images.