United States$5,000,000+
Inventory Delivered By
O
Oliver Price
5
Cisco ISR 4221 delivers stable routing and UC performance. Ideal for small offices with predictable workloads.
ISR4221/K9
Cisco ISR 4221 (2GE,2NIM,8G FLASH,4G DRAM,IPB)
FEATURED DEAL
Name:
ISR4221/K9
- Description:
- Cisco ISR 4221 (2GE,2NIM,8G FLASH,4G DRAM,IPB)
- Rating:
Added to cart 28 times recently
- Availability:
In stock - Ready to Ship
- Brand:
- Cisco
- GTIN:
- 818242357789
- Condition:
- Warranty:
- 3
- List Price:
$2,131.00
- Price:
$625.0070.7% off
Quantity:
1
Business price:
3 Year Extended Warranty
Same-day Shipping
14-Day Money Back Guarantee
Shipping:
Payment:
3 Year Extended Warranty
Same-day Shipping
14-Day Money Back Guarantee
Need Additional Discount on Product?
Request a quote below - Get Exclusive Pricing and Support.
Shipping:
Payment:
TRUSTED, TRIED, PROVEN
Officially Accredited
& Verified By
Next-Gen IT
Solutions Powered By
ISR4221/K9 Overview
ISR4221/K9 is a fixed, enterprise-class router engineered for branch deployments with integrated services that ensure robust VPN features, comprehensive security, and high-performance routing. It delivers flexible power options through an AC Power Supply, supports dual WAN configurations with dedicated 10/100/1000 Ethernet ports for both WAN and LAN connectivity, and offers modular capabilities via EHWIC slots for enhanced network expansion.
ISR4221/K9 integrates advanced routing protocols including OSPF, EIGRP, BGP, and RIP, while its built-in firewall and VPN support (IPSec, SSL VPN, DMVPN) guarantee secure data transmission. Designed to handle up to 0.3 Gbps throughput with high availability and redundancy, it is ideally suited for enterprise environments requiring unified communications, voice and video services, and robust WAN optimization without compromise.
ISR4221/K9 price is $625.00, a 70.7% saving from the Cisco list price of $2,131.00. ISR4221/K9 is in stock and available for next-day dispatch. (terms applied)
Request bulk order quote for ISR4221/K9 for additional pricing. Browse the full Router Isr 4000 series or explore all Cisco products.
ISR4221/K9 Specifications
- Product Type
- Enterprise Router
- VPN Support
- IPSec / SSL VPN / DMVPN
- Power Source
- AC Power Supply
- Routing Protocols
- OSPF / BGP / EIGRP / RIP / Static Routing
- Broadband
- N/A
- Architecture
- Fixed
- WAN Configuration
- Dual WAN
- WAN Ports
- 2 WAN
- LAN Ports
- 4 LAN Ports
- Ethernet Technology
- 10/100/1000
- Wi-Fi Standard
- N/A
- Connectivity Type
- Wired
- Network Protocols
- IPv4 / IPv6 / OSPF / EIGRP / BGP / RIP
- Remote Management
- CLI / SNMP / Cisco SDM
- Compliance Standards
- FCC / CE
- Wireless Support
- No
- Speed/Capacity
- Gigabit
- Firewall Features
- Yes
- Features
- VPN / VoIP / IPv6 Compatible / Firewall / MPLS / QoS
- Use Case
- Enterprise
- Management
- Managed
- Form Factor
- Rack-mount
- Integrated Services
- Voice / Video
- High Availability Support
- Supported
- Safety
- N/A
- EMC
- N/A
- Telecom
- N/A
- Throughput Capacity
- 0.3 Gbps
- QoS Features
- Supported
- Built-in Security Features
- Firewall / Intrusion Prevention / Malware Protection
- Expansion Slots
- EHWIC
- Modular Slots Available
- 2 Slots
- Stacking Capability
- No
- 5G Support
- No
- Memory
- 1 GB
- Flash Memory
- 256 MB
- Interface Ports
- RJ-45 / EHWIC
- Power
- 65 Watt
- Device Type
- Router
- Product Name
- Cisco ISR 4221/K9
- Height
- 1.73 inches
- Width
- 17.3 inches
- Depth
- 15.7 inches
- Weight
- 10.4 lbs
ISR4221/K9 Use Case
Secure SD-WAN Edge for Distributed Branch Offices
In a multinational enterprise deploying Cisco SD-WAN at remote sites, the Cisco ISR4221/K9 serves as a compact yet powerful SD-WAN edge router. Leveraging its dual GE WAN interfaces, two NIM slots for 4G-LTE backup, 8 GB Flash and 4 GB DRAM, it delivers encrypted tunnels, application-aware routing, and zero-touch provisioning across 50+ branch locations. Outcome: 99.9% uptime, 40% reduction in operational expenses, and consistent user experience.
Integrated Firewall and Secure Internet Gateway for SMB Retail Chains
An SMB retail chain uses the Cisco ISR4221/K9 as a unified threat management appliance. Built-in Cisco zone-based firewall, IPS, and NAT combine with 8 GB Flash and the IP Base license to secure POS transactions and guest Wi-Fi. Dual 1 GE interfaces support WAN diversification while rapid firmware upgrades are stored on flash. Outcome: PCI-DSS compliance, 30% faster threat response, and 25% lower total cost of ownership.
Converged IoT and Voice Deployment in Smart Manufacturing Sites
A manufacturing plant aggregates IoT sensors, surveillance cameras, and VoIP phones through the Cisco ISR4221/K9. Two NIM slots enable WAN redundancy and LTE failover; advanced QoS prioritizes voice and machine-critical data; and the IP Base license enforces secure segmentation. Outcome: 50% improvement in real-time monitoring accuracy, 20% boost in production efficiency, and simplified centralized network management.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table
 ISR4221/K9 |  ISR4321-SEC/K9 |  C1-CISCO4331/K9 |  C1-CISCO4321/K9 |  ISR4221-SEC/K9 | |
|---|---|---|---|---|---|
| 5G Support | No | No | No | No | No |
| Architecture | Fixed | Fixed | Modular | Modular | Fixed |
| Broadband | N/A | N/A | N/A | N/A | N/A |
| Built-in Security Features | Firewall / Intrusion Prevention / Malware Protection | Firewall, Intrusion Prevention, Malware Protection | Firewall, Intrusion Prevention, Malware Protection | Firewall / Intrusion Prevention | Firewall / Intrusion Prevention |
| Compliance Standards | FCC / CE | FCC, CE | FCC, CE | FCC / CE | IEEE 802.3, FCC, CE |
| Connectivity Type | Wired | Wired | Wired | Wired | Wired |
| Depth | 15.7 inches | N/A | 16.5 inches | 20 inches | 11.3 inches |
| Device Type | Router | Router | Router | Router | Router |
| EMC | N/A | N/A | FCC Compliant | N/A | CISPR 22 |
| Ethernet Technology | 10/100/1000 | 10/100/1000 | 10/100/1000 | 10/100/1000 | 10/100/1000 |
| Expansion Slots | EHWIC | NIM, EHWIC | NIM / EHWIC | NIM / EHWIC | EHWIC |
| Features | VPN / VoIP / IPv6 Compatible / Firewall / MPLS / QoS | VPN, Firewall, IPv6 Compatible | VPN, Voice, Video, Integrated Services, Firewall | VPN / VoIP / IPv6 Compatible / Firewall / WAN Optimization | VPN / IPv6 Compatible / Firewall |
| Firewall Features | Yes | Yes | Yes | Yes | Yes |
| Flash Memory | 256 MB | 1 GB | 2 GB | 512 MB | 1 GB |
| Form Factor | Rack-mount | Rack-mount | Rack-mount | Rack-mount | Desktop |
| Height | 1.73 inches | N/A | 1.75 inches | 1.75 inches | 1.73 inches |
| High Availability Support | Supported | Supported | Supported | Supported | Supported |
| Integrated Services | Voice / Video | Voice, Video, WAN Optimization | Voice, Video, WAN Optimization | Voice / Video / WAN Optimization | Voice / Video |
| Interface Ports | RJ-45 / EHWIC | RJ-45, SFP | RJ-45, SFP | RJ-45 / SFP | RJ-45 |
| LAN Ports | 4 LAN Ports | 2 LAN Ports | 4 LAN Ports | Modular LAN | 4 LAN Ports |
| Management | Managed | Managed | Managed | Managed | Managed |
| Memory | 1 GB | 2 GB | 4 GB | 1 GB | 1 GB |
| Modular Slots Available | 2 Slots | 1 Slot | 2 Slots | 2 Slots | 1 Slot |
| Network Protocols | IPv4 / IPv6 / OSPF / EIGRP / BGP / RIP | IPv4, IPv6 | OSPF, BGP, EIGRP, RIP, MPLS | IPv4, IPv6 | IPv4, IPv6 |
| Power | 65 Watt | 75W | 115W | 110 W | 65W |
| Power Source | AC Power Supply | AC Power Supply / DC Power Supply (Redundant) | AC Power Supply / Redundant | AC Power Supply with Redundant Options | AC Power Supply / Redundant |
| Product Name | Cisco ISR 4221/K9 | Cisco ISR4321-SEC/K9 | Cisco 4331 Integrated Services Router | Cisco 4321 Integrated Services Router (C1-CISCO4321/K9) | Cisco ISR 4221-SEC/K9 |
| Product Type | Enterprise Router | Enterprise Router | Enterprise Router | Enterprise Router | Enterprise Router |
| QoS Features | Supported | Supported | Supported | Supported | Supported |
| Remote Management | CLI / SNMP / Cisco SDM | SSH, Telnet, SNMP | Cisco SDM, SSH, Telnet | SSH / Telnet / SNMP | SSH, Telnet, SNMP |
| Routing Protocols | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / MPLS / IS-IS / RIP / Static Routing | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / RIP / Static Routing / MPLS |
| Safety | N/A | N/A | UL Listed | N/A | UL, cUL |
| Speed/Capacity | Gigabit | Gigabit | Gigabit | Gigabit | Gigabit |
| Stacking Capability | No | No | Yes | No | No |
| Telecom | N/A | N/A | TIA/EIA | N/A | FCC Part 15 |
| Throughput Capacity | 0.3 Gbps | 300 Mbps | 100 Mbps | 0.15 Gbps | 300 Mbps |
| Use Case | Enterprise | Enterprise, Small Business | Enterprise / Branch | Enterprise | Enterprise |
| VPN Support | IPSec / SSL VPN / DMVPN | IPSec / SSL VPN / DMVPN / FlexVPN | IPSec / SSL VPN / DMVPN / FlexVPN | IPSec / SSL VPN / DMVPN / FlexVPN | IPSec / SSL VPN / DMVPN / FlexVPN |
| WAN Configuration | Dual WAN | Dual WAN | Dual WAN | Dual WAN | Dual WAN |
| WAN Ports | 2 WAN | 2 WAN Ports | 2 WAN | 2 WAN | 2 WAN |
| Weight | 10.4 lbs | N/A | 17.6 lbs | 14 lbs | 8.6 lbs |
| Wi-Fi Standard | N/A | N/A | N/A | N/A | N/A |
| Width | 17.3 inches | N/A | 17.3 inches | 17.5 inches | 17.2 inches |
| Wireless Support | No | No | No | No | No |
Reviews & Ratings
E
Emma Jenkins
4
Durable and reliable. Supports 2GE, 2NIM, and multiple endpoints efficiently without downtime.
L
Lucas Morgan
5
Easy to configure and maintain. Provides consistent UC, voice, and network operations across branch offices.
M
Mia Foster
3
Reliable Cisco solution. Maintains seamless UC, voice, and data communications in small to medium branches.
J
James Riley
4
High-performing and robust. Perfect for offices needing secure and reliable routing with UC support.
Questions & Answers
What is the Cisco ISR 4221 (SKU ISR4221/K9)?
The Cisco ISR 4221 (SKU ISR4221/K9) is a compact branch router delivering integrated routing, security, and application services in a single platform.
What key features does the Cisco ISR 4221 offer?
Key features include two Gigabit Ethernet ports, two NIM expansion slots, 4 GB DRAM, 8 GB flash memory, hardware encryption, and an internal power supply.
What throughput performance can I expect from the ISR 4221?
The ISR 4221 delivers up to 50 Mbps aggregate throughput by default and can be boosted to 100 Mbps with an optional Performance on Demand license.
Which physical interfaces and expansion options are available?
It features two 10/100/1000 Mbps RJ-45 ports and two Network Interface Module (NIM) slots supporting additional Ethernet, T1/E1, DSL, or cellular modules.