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ISR4221-SEC/K9
Cisco ISR 4221 SEC Bundle with SEC lic
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ISR4221-SEC/K9 is a fixed enterprise router designed to deliver robust performance with integrated security, featuring dual WAN and four LAN Gigabit Ethernet interfaces that support high throughput and advanced VPN capabilities. Built with an AC power supply option and redundant power support, its architecture ensures reliable operations for branch office environments while delivering integrated services such as voice and video to meet modern communication demands.
ISR4221-SEC/K9 further enhances network performance with modular expansion capabilities through a dedicated EHWIC slot, advanced firewall features, and support for standard routing protocols including OSPF, BGP, EIGRP, RIP, Static Routing, and MPLS. Its proven performance, high availability support, and versatile use case suitability make it an ideal solution for enterprise and small business deployments that require secure, high-speed connectivity and integrated services.
ISR4221-SEC/K9 price is $2,041.00, a 36.6% saving from the Cisco list price of $3,217.00. ISR4221-SEC/K9 is in stock and available for next-day dispatch. (terms applied)
Request bulk order quote for ISR4221-SEC/K9 for additional pricing. Browse the full Router Isr 4000 series or explore all Cisco products.
Leverage the ISR4221-SEC/K9 bundle to provision secure, policy-based SD-WAN tunnels across 50+ retail branches via zero-touch deployment. Outcome: 40% reduction in provisioning time, dynamic path selection for high-availability traffic, and end-to-end AES-256 encryption that ensures PCI DSS compliance and consistent user experience.
Deploy Cisco ISR4221-SEC at manufacturing sites to segment OT and IT networks, enforce contextual access policies using integrated firewall, IPS, and URL filtering. Outcome: Meets NIST SP 800-82 security guidelines, reduces lateral threat movement by 75%, and delivers real-time visibility into device posture for accelerated incident response.
Use ISR4221-SEC/K9 to establish DMVPN/IPsec tunnels to AWS and Azure VPCs with built-in secure segmentation and traffic optimization. Outcome: Achieve 99.99% uptime SLA, eliminate MPLS costs with automated path failover, and ensure enterprise-grade encryption and compliance for multi-cloud applications.
To get the detailed certification, please go to the Compliance Center.
| 5G Support | No | No | No | No | No |
| Architecture | Fixed | Fixed | Fixed | Modular | Modular |
| Broadband | N/A | N/A | N/A | N/A | N/A |
| Built-in Security Features | Firewall / Intrusion Prevention | Firewall / Intrusion Prevention / Malware Protection | Firewall, Intrusion Prevention, Malware Protection | Firewall, Intrusion Prevention, Malware Protection | Firewall, Intrusion Prevention, Malware Protection |
| Compliance Standards | IEEE 802.3, FCC, CE | FCC, CE | FCC, CE, RoHS | FCC, CE, RoHS | FCC, CE, UL |
| Connectivity Type | Wired | Wired | Wired / Wireless / Ethernet | Wired | Wired |
| Depth | 11.3 inches | 18.3 inches | N/A | 20 inches | 14.1 in |
| Device Type | Router | Router | Router | Router | Router |
| EMC | CISPR 22 | CISPR22, FCC Part 15 | N/A | N/A | N/A |
| Ethernet Technology | 10/100/1000 | 10/100/1000 | 10/100/1000 | 10/100/1000 | 10/100/1000 |
| Expansion Slots | EHWIC | NIM / EHWIC | EHWIC, NIM | EHWIC / NIM | NIM, EHWIC |
| Features | VPN / IPv6 Compatible / Firewall | Mesh / VPN / VoIP / IPv6 Compatible / Firewall / MPLS | VPN, Voice, Video, IPv6 Compatible, Firewall, POE, Integrated Services | VPN / Firewall / IPv6 Compatible | VPN, IPv6 Compatible, Firewall, Intrusion Prevention System |
| Firewall Features | Yes | Yes | Yes | Yes | Yes |
| Flash Memory | 1 GB | 256 MB | 1 GB | 512 MB | 512 MB |
| Form Factor | Desktop | Rack-mount / Desktop | Rack-mount | Rack-mount | Rack-mount |
| Height | 1.73 inches | 1.75 inches | N/A | 1.73 inches | 1.75 in |
| High Availability Support | Supported | Supported | Supported | Supported | Supported |
| Integrated Services | Voice / Video | Voice / Video / WAN Optimization | Voice, Video, WAN Optimization | Voice, Video, WAN Optimization | Voice, Video, WAN Optimization |
| Interface Ports | RJ-45 | RJ-45 / SFP | RJ-45, SFP, Combo Ports | RJ-45, SFP | RJ-45, SFP |
| LAN Ports | 4 LAN Ports | 4 LAN Ports | 4 LAN Ports | 4 LAN Ports | 4 LAN Ports |
| Management | Managed | Managed | Managed | Managed | Managed |
| Memory | 1 GB | 512 MB | 4 GB | 4 GB | 4 GB |
| Modular Slots Available | 1 Slot | 2 Slots | 2 Slots | 3+ Slots | 2 Slots |
| Network Protocols | IPv4, IPv6 | IPv4, IPv6 | OSPF, BGP, EIGRP, RIP, Static Routing | IPv4, IPv6 | Ethernet, Fast Ethernet, Gigabit Ethernet |
| Power | 65W | 54 W | 350 W | 350 W | 350 W |
| Power Source | AC Power Supply / Redundant | AC Power Supply / Redundant | AC Power Supply with Redundant Option | AC Power Supply / Redundant | AC Power Supply / Redundant |
| Product Name | Cisco ISR 4221-SEC/K9 | Cisco ISR4321-AXV/K9 | ISR4461-AX/K9 | Cisco ISR 4461/K9 Integrated Services Router | Cisco ISR4451-X-SEC/K9 |
| Product Type | Enterprise Router | Enterprise Router | Enterprise Router | Integrated Services Router | Enterprise Router |
| QoS Features | Supported | Supported | Supported | Supported | Supported |
| Remote Management | SSH, Telnet, SNMP | SSH, Telnet, SNMP | CLI, HTTP, SNMP | SSH / Telnet / SNMP | SSH, Telnet, SNMP |
| Routing Protocols | OSPF / BGP / EIGRP / RIP / Static Routing / MPLS | OSPF / BGP / EIGRP / MPLS / IS-IS / RIP / Static Routing | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / MPLS / IPv6 / Static Routing |
| Safety | UL, cUL | RoHS Compliant | N/A | N/A | N/A |
| Speed/Capacity | Gigabit | Gigabit | Gigabit | Gigabit | Gigabit |
| Stacking Capability | No | Yes | Yes | Yes | No |
| Telecom | FCC Part 15 | TIA/EIA | N/A | N/A | N/A |
| Throughput Capacity | 300 Mbps | 200 Mbps | 1 Gbps | 2 Gbps | 2 Gbps |
| Use Case | Enterprise | Enterprise / Branch | Enterprise / Branch Office | Enterprise | Enterprise |
| VPN Support | IPSec / SSL VPN / DMVPN / FlexVPN | IPSec / SSL VPN / DMVPN / FlexVPN | IPSec / SSL VPN / DMVPN / FlexVPN / N/A | IPSec / SSL VPN / DMVPN / FlexVPN | IPSec / SSL VPN / DMVPN / N/A |
| WAN Configuration | Dual WAN | Dual WAN | Dual WAN | Dual WAN | Dual WAN |
| WAN Ports | 2 WAN | 2 WAN | 2 WAN | 2 WAN | 2 WAN |
| Weight | 8.6 lbs | 13.2 lbs | N/A | 25 lbs | 21 lbs |
| Wi-Fi Standard | N/A | N/A | WiFi 6 (802.11ax) | N/A | N/A |
| Width | 17.2 inches | 17.5 inches | N/A | 17.5 inches | 17.5 in |
| Wireless Support | No | No | Yes | No | No |
Solid security router for smaller branches. Stable and easy to deploy.
Good performance with security services enabled. Reliable choice.
Cisco ISR stability with essential security features. Meets expectations.
Handles VPN and firewall tasks smoothly. No issues so far.
Practical and dependable router for secure branch connectivity.
The Cisco ISR 4221 SEC Bundle (ISR4221-SEC/K9) is an Integrated Services Router optimized for secure small-branch deployments, including a built-in security (SEC) license that enables advanced threat defense and VPN services.
The SEC license activates Cisco’s advanced security suite, including firewall, intrusion prevention (IPS), URL filtering, malware defense, and secure VPN termination for up to 50 tunnels.
The ISR 4221 SEC delivers up to 50 Mbps of firewall throughput and 35 Mbps of IPsec VPN performance when all security features are enabled.
It supports up to 50 IPsec VPN tunnels concurrently, providing secure site-to-site and remote-access connectivity.