United States$5,000,000+
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Richard Evans
5
Solid security router for smaller branches. Stable and easy to deploy.
ISR4221-SEC/K9
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Cisco ISR 4221 SEC Bundle with SEC lic
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Name:
ISR4221-SEC/K9
- Description:
- Cisco ISR 4221 SEC Bundle with SEC lic
- Rating:
Added to cart 28 times recently
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In stock - Ready to Ship
- Brand:
- Cisco
- GTIN:
- 661541411184
- Condition:
- Warranty:
- 3
- List Price:
$3,217.00
- Price:
$2,041.0036.6% off
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1
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ISR4221-SEC/K9 Overview
ISR4221-SEC/K9 is a fixed enterprise router designed to deliver robust performance with integrated security, featuring dual WAN and four LAN Gigabit Ethernet interfaces that support high throughput and advanced VPN capabilities. Built with an AC power supply option and redundant power support, its architecture ensures reliable operations for branch office environments while delivering integrated services such as voice and video to meet modern communication demands.
ISR4221-SEC/K9 further enhances network performance with modular expansion capabilities through a dedicated EHWIC slot, advanced firewall features, and support for standard routing protocols including OSPF, BGP, EIGRP, RIP, Static Routing, and MPLS. Its proven performance, high availability support, and versatile use case suitability make it an ideal solution for enterprise and small business deployments that require secure, high-speed connectivity and integrated services.
ISR4221-SEC/K9 price is $2,041.00, a 36.6% saving from the Cisco list price of $3,217.00. ISR4221-SEC/K9 is in stock and available for next-day dispatch. (terms applied)
Request bulk order quote for ISR4221-SEC/K9 for additional pricing. Browse the full Router Isr 4000 series or explore all Cisco products.
ISR4221-SEC/K9 Specifications
- Ethernet Technology
- 10/100/1000
- Height
- 1.73 inches
- Depth
- 11.3 inches
- Width
- 17.2 inches
- Form Factor
- Desktop
- Weight
- 8.6 lbs
- Product Type
- Enterprise Router
- Architecture
- Fixed
- WAN Configuration
- Dual WAN
- WAN Ports
- 2 WAN
- Wi-Fi Standard
- N/A
- Connectivity Type
- Wired
- Wireless Support
- No
- Firewall Features
- Yes
- Management
- Managed
- QoS Features
- Supported
- Stacking Capability
- No
- 5G Support
- No
- Interface Ports
- RJ-45
- Device Type
- Router
- VPN Support
- IPSec / SSL VPN / DMVPN / FlexVPN
- Network Protocols
- IPv4, IPv6
- Remote Management
- SSH, Telnet, SNMP
- High Availability Support
- Supported
- Expansion Slots
- EHWIC
- Broadband
- N/A
- Features
- VPN / IPv6 Compatible / Firewall
- Use Case
- Enterprise
- Integrated Services
- Voice / Video
- Modular Slots Available
- 1 Slot
- LAN Ports
- 4 LAN Ports
- Safety
- UL, cUL
- Built-in Security Features
- Firewall / Intrusion Prevention
- Power Source
- AC Power Supply / Redundant
- Power
- 65W
- Speed/Capacity
- Gigabit
- Memory
- 1 GB
- Flash Memory
- 1 GB
- Compliance Standards
- IEEE 802.3, FCC, CE
- Throughput Capacity
- 300 Mbps
- Telecom
- FCC Part 15
- Routing Protocols
- OSPF / BGP / EIGRP / RIP / Static Routing / MPLS
- EMC
- CISPR 22
- Product Name
- Cisco ISR 4221-SEC/K9
ISR4221-SEC/K9 Use Case
Optimized SD-WAN and Zero-Touch Provisioning for Branch Offices
Leverage the ISR4221-SEC/K9 bundle to provision secure, policy-based SD-WAN tunnels across 50+ retail branches via zero-touch deployment. Outcome: 40% reduction in provisioning time, dynamic path selection for high-availability traffic, and end-to-end AES-256 encryption that ensures PCI DSS compliance and consistent user experience.
Zero-Trust Segmentation for Industrial IoT Networks
Deploy Cisco ISR4221-SEC at manufacturing sites to segment OT and IT networks, enforce contextual access policies using integrated firewall, IPS, and URL filtering. Outcome: Meets NIST SP 800-82 security guidelines, reduces lateral threat movement by 75%, and delivers real-time visibility into device posture for accelerated incident response.
Encrypted Hybrid-Cloud Connectivity for Secure Multi-Cloud Access
Use ISR4221-SEC/K9 to establish DMVPN/IPsec tunnels to AWS and Azure VPCs with built-in secure segmentation and traffic optimization. Outcome: Achieve 99.99% uptime SLA, eliminate MPLS costs with automated path failover, and ensure enterprise-grade encryption and compliance for multi-cloud applications.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table 
| ISR4221-SEC/K9 |  ISR4321-AXV/K9 |  ISR4461-AX/K9 |  ISR4461/K9 |  ISR4451-X-SEC/K9 | |
|---|---|---|---|---|---|
| 5G Support | No | No | No | No | No |
| Architecture | Fixed | Fixed | Fixed | Modular | Modular |
| Broadband | N/A | N/A | N/A | N/A | N/A |
| Built-in Security Features | Firewall / Intrusion Prevention | Firewall / Intrusion Prevention / Malware Protection | Firewall, Intrusion Prevention, Malware Protection | Firewall, Intrusion Prevention, Malware Protection | Firewall, Intrusion Prevention, Malware Protection |
| Compliance Standards | IEEE 802.3, FCC, CE | FCC, CE | FCC, CE, RoHS | FCC, CE, RoHS | FCC, CE, UL |
| Connectivity Type | Wired | Wired | Wired / Wireless / Ethernet | Wired | Wired |
| Depth | 11.3 inches | 18.3 inches | N/A | 20 inches | 14.1 in |
| Device Type | Router | Router | Router | Router | Router |
| EMC | CISPR 22 | CISPR22, FCC Part 15 | N/A | N/A | N/A |
| Ethernet Technology | 10/100/1000 | 10/100/1000 | 10/100/1000 | 10/100/1000 | 10/100/1000 |
| Expansion Slots | EHWIC | NIM / EHWIC | EHWIC, NIM | EHWIC / NIM | NIM, EHWIC |
| Features | VPN / IPv6 Compatible / Firewall | Mesh / VPN / VoIP / IPv6 Compatible / Firewall / MPLS | VPN, Voice, Video, IPv6 Compatible, Firewall, POE, Integrated Services | VPN / Firewall / IPv6 Compatible | VPN, IPv6 Compatible, Firewall, Intrusion Prevention System |
| Firewall Features | Yes | Yes | Yes | Yes | Yes |
| Flash Memory | 1 GB | 256 MB | 1 GB | 512 MB | 512 MB |
| Form Factor | Desktop | Rack-mount / Desktop | Rack-mount | Rack-mount | Rack-mount |
| Height | 1.73 inches | 1.75 inches | N/A | 1.73 inches | 1.75 in |
| High Availability Support | Supported | Supported | Supported | Supported | Supported |
| Integrated Services | Voice / Video | Voice / Video / WAN Optimization | Voice, Video, WAN Optimization | Voice, Video, WAN Optimization | Voice, Video, WAN Optimization |
| Interface Ports | RJ-45 | RJ-45 / SFP | RJ-45, SFP, Combo Ports | RJ-45, SFP | RJ-45, SFP |
| LAN Ports | 4 LAN Ports | 4 LAN Ports | 4 LAN Ports | 4 LAN Ports | 4 LAN Ports |
| Management | Managed | Managed | Managed | Managed | Managed |
| Memory | 1 GB | 512 MB | 4 GB | 4 GB | 4 GB |
| Modular Slots Available | 1 Slot | 2 Slots | 2 Slots | 3+ Slots | 2 Slots |
| Network Protocols | IPv4, IPv6 | IPv4, IPv6 | OSPF, BGP, EIGRP, RIP, Static Routing | IPv4, IPv6 | Ethernet, Fast Ethernet, Gigabit Ethernet |
| Power | 65W | 54 W | 350 W | 350 W | 350 W |
| Power Source | AC Power Supply / Redundant | AC Power Supply / Redundant | AC Power Supply with Redundant Option | AC Power Supply / Redundant | AC Power Supply / Redundant |
| Product Name | Cisco ISR 4221-SEC/K9 | Cisco ISR4321-AXV/K9 | ISR4461-AX/K9 | Cisco ISR 4461/K9 Integrated Services Router | Cisco ISR4451-X-SEC/K9 |
| Product Type | Enterprise Router | Enterprise Router | Enterprise Router | Integrated Services Router | Enterprise Router |
| QoS Features | Supported | Supported | Supported | Supported | Supported |
| Remote Management | SSH, Telnet, SNMP | SSH, Telnet, SNMP | CLI, HTTP, SNMP | SSH / Telnet / SNMP | SSH, Telnet, SNMP |
| Routing Protocols | OSPF / BGP / EIGRP / RIP / Static Routing / MPLS | OSPF / BGP / EIGRP / MPLS / IS-IS / RIP / Static Routing | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / RIP / Static Routing | OSPF / BGP / EIGRP / MPLS / IPv6 / Static Routing |
| Safety | UL, cUL | RoHS Compliant | N/A | N/A | N/A |
| Speed/Capacity | Gigabit | Gigabit | Gigabit | Gigabit | Gigabit |
| Stacking Capability | No | Yes | Yes | Yes | No |
| Telecom | FCC Part 15 | TIA/EIA | N/A | N/A | N/A |
| Throughput Capacity | 300 Mbps | 200 Mbps | 1 Gbps | 2 Gbps | 2 Gbps |
| Use Case | Enterprise | Enterprise / Branch | Enterprise / Branch Office | Enterprise | Enterprise |
| VPN Support | IPSec / SSL VPN / DMVPN / FlexVPN | IPSec / SSL VPN / DMVPN / FlexVPN | IPSec / SSL VPN / DMVPN / FlexVPN / N/A | IPSec / SSL VPN / DMVPN / FlexVPN | IPSec / SSL VPN / DMVPN / N/A |
| WAN Configuration | Dual WAN | Dual WAN | Dual WAN | Dual WAN | Dual WAN |
| WAN Ports | 2 WAN | 2 WAN | 2 WAN | 2 WAN | 2 WAN |
| Weight | 8.6 lbs | 13.2 lbs | N/A | 25 lbs | 21 lbs |
| Wi-Fi Standard | N/A | N/A | WiFi 6 (802.11ax) | N/A | N/A |
| Width | 17.2 inches | 17.5 inches | N/A | 17.5 inches | 17.5 in |
| Wireless Support | No | No | Yes | No | No |
Reviews & Ratings
P
Paul Jennings
5
Good performance with security services enabled. Reliable choice.
S
Simon Carter
4
Cisco ISR stability with essential security features. Meets expectations.
O
Oliver Matthews
4
Handles VPN and firewall tasks smoothly. No issues so far.
D
Duncan Walsh
5
Practical and dependable router for secure branch connectivity.
Questions & Answers
What is the Cisco ISR 4221 SEC Bundle with SEC license (SKU: ISR4221-SEC/K9)?
The Cisco ISR 4221 SEC Bundle (ISR4221-SEC/K9) is an Integrated Services Router optimized for secure small-branch deployments, including a built-in security (SEC) license that enables advanced threat defense and VPN services.
Which security features are included in the SEC license for the ISR 4221?
The SEC license activates Cisco’s advanced security suite, including firewall, intrusion prevention (IPS), URL filtering, malware defense, and secure VPN termination for up to 50 tunnels.
What is the performance throughput of the Cisco ISR 4221 SEC Bundle?
The ISR 4221 SEC delivers up to 50 Mbps of firewall throughput and 35 Mbps of IPsec VPN performance when all security features are enabled.
How many VPN tunnels does the ISR 4221 SEC support?
It supports up to 50 IPsec VPN tunnels concurrently, providing secure site-to-site and remote-access connectivity.
What WAN connection options are available on the Cisco ISR 4221 SEC?
The router offers two onboard GE WAN ports, one integrated DSL interface module (optional), and support for LTE cellular connectivity via an external modem.
Can I manage the ISR 4221 SEC Bundle centrally?
Yes, it integrates with Cisco DNA Center and Cisco Prime Infrastructure for centralized policy, lifecycle, and configuration management.
What are the hardware specifications of the ISR 4221 SEC?
The ISR 4221 SEC features a dual-core 1.2 GHz CPU, 2 GB of DRAM (upgradeable), 4 GB of flash storage, and modular WAN slot capacity.
Is the Cisco ISR 4221 SEC suitable for small branch offices?
Absolutely; it’s designed for small branches that need enterprise-grade security, application performance, and scalable WAN connectivity.
How do I install the SEC license on the ISR 4221?
Simply order the SEC license entitlement, receive a PAK code, then use the Cisco licensing portal or CLI ‘license install’ command to activate.
What deployment models does the ISR 4221 SEC support?
It supports on-premises, cloud-managed (Cisco SD-WAN), and hybrid WAN deployments with flexible licensing and overlay options.
Does the ISR 4221 SEC support quality of service (QoS)?
Yes, it includes advanced QoS features such as traffic shaping, class-based policing, and priority queuing to ensure application performance.
What software images are compatible with the ISR 4221 SEC Bundle?
It runs Cisco IOS XE software, supporting performance-optimized, universal, and security-optimized feature sets.
How scalable is the Cisco ISR 4221 SEC?
Scalability options include modular interface adapters, memory expansions up to 4 GB, and optional Network Interface Modules (NIMs) for growth.
What warranty and support options are available for the ISR4221-SEC/K9?
Cisco offers a limited lifetime hardware warranty plus optional SMARTnet support for updates, 24/7 TAC access, and advance hardware replacement.
Can the ISR 4221 SEC Bundle be integrated into a Cisco SD-WAN environment?
Yes, the router fully supports Cisco SD-WAN with vEdge feature parity, centralized orchestration, and secure overlay connectivity.
How does the SEC license enhance data protection on the ISR 4221?
The SEC license adds real-time threat intelligence, malware sandboxing, and encrypted traffic inspection to safeguard data in motion and at rest.