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Balanced CTO server for mixed workloads.
P14279-B21
HPE ProLiant DL385 Gen10 Plus 24 SFF CTO Server
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P14279-B21
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- HPE ProLiant DL385 Gen10 Plus 24 SFF CTO Server
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P14279-B21 Overview
P14279-B21 is a high-performance rackmount server engineered to support Intel Xeon Scalable processors on an LGA 4189 socket and enables dual-processor (2P) scalability for demanding enterprise workloads. It features ECC DDR4 memory with 16 slots supporting up to 2 TB capacity, 4 PCIe expansion slots running at PCIe 4.0, and hot-swap enabled storage bays that accommodate 8 x 3.5-inch drives with RAID 0/1/5/10 support.
The server is equipped with dual 10GbE network interfaces, redundant power supplies rated at 750W, and active cooling to ensure stable operation in data center environments. Remote management is provided via iDRAC, and the platform supports a range of operating systems, including Windows Server, VMware ESXi, Ubuntu, and RHEL, making it ideal for virtualization, file serving, application hosting, and other mission-critical applications.
P14279-B21 price is is available on request. Get immediate quote.
Request bulk order quote for P14279-B21 for additional pricing. Browse the full Hpe Proliant Dl385 Gen10 Plus Servers series or explore all Hpe products.
P14279-B21 Specifications
- Product Type
- Server
- Form Factor
- Rackmount
- Rack Units
- 2U
- Processor Brand
- Intel
- Processor Series
- Intel Xeon Scalable
- Processor Generation
- Xeon 4th Gen
- Use Case
- Virtualization
- CPU Socket
- LGA 4189
- Scalability
- 2P
- Max Cores per CPU
- 32
- Max Threads per CPU
- 64
- RAM Type
- ECC DDR4
- RAM Slots
- 16
- Max RAM Capacity
- 2 TB
- Storage Type
- SATA SSD
- Storage Bays
- 8
- Drive Bay Size
- 3.5-inch
- Hot-Swap Support
- Yes
- RAID Support
- RAID 0/1/5/10
- PCIe Slots
- 4
- PCIe Version
- PCIe 4.0
- Network Interface
- 10GbE
- LAN Ports
- 2
- Remote Management
- iDRAC
- Power Supply
- Redundant
- Power Supply Wattage
- 750W
- Cooling
- Active
- Operating System
- Windows Server
- Virtualization Ready
- Yes
- GPU Support
- No
- Rail Kit Included
- Yes
- Product Name
- P14279-B21
- Height
- 3.5 inches
- Width
- 17.3 inches
- Depth
- 28.0 inches
- Weight
- 45 lbs
P14279-B21 Use Case
Multi-Tenant Virtualization and Cloud Hosting
In a managed services environment, the P14279-B21 HPE ProLiant DL385 Gen10 Plus 24 SFF CTO Server consolidates hundreds of Linux and Windows VMs via VMware vSphere or HPE OneView, delivering 3× higher virtual machine density and reducing TCO by 30%. Benefit: on-demand scalability, enterprise-grade security and 99.9% uptime for mission-critical cloud services.
High-Performance Data Analytics and AI/ML Workloads
A financial services firm leverages the P14279-B21 HPE ProLiant DL385 Gen10 Plus with AMD EPYC™ processors to power Monte Carlo simulations, real-time risk analytics and AI model training. The platform doubles data processing throughput and scales to 1.5 PB NVMe storage. Benefit: faster time-to-insight, improved forecasting accuracy and a 50% reduction in nightly batch windows.
Mission-Critical SAP HANA and Enterprise Database Consolidation
A global retail chain deploys P14279-B21 HPE ProLiant DL385 Gen10 Plus 24 SFF CTO Servers to host SAP HANA in-memory databases and Oracle workloads. The solution delivers sub-millisecond transaction latency, 99.99% availability and a simplified two-node cluster architecture. Benefit: lower licensing costs, seamless seasonal scaling and streamlined maintenance.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table
 P14279-B21 |  P07598-B21 |  P14278-B21 |  P14280-B21 |  P07597-B21 | |
|---|---|---|---|---|---|
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Cooling | Active | Active | Active | Active | Active |
| Depth | 28.0 inches | 28 inches | 28 inches | 28.0 inches | 28 inches |
| Drive Bay Size | 3.5-inch | Mixed | 2.5-inch | 3.5-inch | 3.5-inch |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | No | No | Yes | No | Yes |
| Height | 3.5 inches | 3.5 inches | 3.5 inches | 3.5 inches | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 2 | 4 | 2 | 2 | 2 |
| Max Cores per CPU | 32 | 32 | 32 | 32 | 32 |
| Max RAM Capacity | 2 TB | 1 TB | 512 GB | 512 GB | 1 TB |
| Max Threads per CPU | 64 | 64 | 64 | 64 | 64 |
| Network Interface | 10GbE | 1GbE | 10GbE | 1GbE | 10GbE |
| Operating System | Windows Server | Windows Server / VMware ESXi / RHEL | Windows Server | Windows Server | VMware ESXi |
| PCIe Slots | 4 | 6 | 6 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 750W | 800W | 750W | 750W | 1200W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 4th Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | P14279-B21 | P07598-B21 High Performance Rackmount Server | P14278-B21 | P14280-B21 | P07597-B21 |
| Product Type | Server | Server | Server | Server | Server |
| RAID Support | RAID 0/1/5/10 | RAID 0 / RAID 1 / RAID 5 / RAID 6 / RAID 10 | RAID 10 | RAID 10 | RAID 10 |
| RAM Slots | 16 | 16 | 8 | 8 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| Rail Kit Included | Yes | No | N/A | N/A | Yes |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 8 | 8 | 10 | 8 |
| Storage Type | SATA SSD | SATA SSD | SATA SSD | SATA HDD | SATA SSD |
| Use Case | Virtualization | Virtualization | Virtualization | Virtualization | Virtualization |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 45 lbs | 45 lbs | 45 lbs | 50 lbs | 50 lbs |
| Width | 17.3 inches | 17.5 inches | 17.3 inches | 17.2 inches | 17.5 inches |
Reviews & Ratings
S
Salman Yaqoob
4
Stable and reliable base platform.
J
Jari Virtanen
5
Good flexibility for customization.
P
Peter Collins
3
Easy deployment.
V
Victor Salinas
4
Consistent performance.
Questions & Answers
What are the key specifications of the HPE ProLiant DL385 Gen10 Plus 24 SFF CTO Server?
The HPE ProLiant DL385 Gen10 Plus 24 SFF CTO features dual AMD EPYC™ processors, up to 4 TB DDR4 memory, 24 SFF drive bays, modular RAID, dual M.2 options and integrated HPE iLO management.
Which AMD EPYC processors are supported in the DL385 Gen10 Plus?
The DL385 Gen10 Plus supports AMD EPYC™ 7002 and 7003 Series CPUs, up to 64 cores per processor for high-density compute workloads.
How much memory can the DL385 Gen10 Plus accommodate?
This server supports up to 32 DIMM slots of DDR4 Smart Memory, reaching a maximum capacity of 4 TB with 128 GB RDIMMs or LRDIMMs.
What storage options are available in the 24 SFF configuration?
The CTO model offers 24 SFF (2.5") drive bays supporting SAS, SATA, NVMe SSDs and HPE Persistent Memory for flexible performance and capacity.