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P14280-B21
- Description:
- HPE ProLiant DL385 Gen10 Plus 12 LFF CTO Server
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3 Year Extended Warranty
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Delivery Timelines
Under 100 KG? Ships Express.
Smaller shipments go via DHL or FedEx Express — delivered worldwide in approximately 3 business days.
Over 100 KG? Ships via Freight.
Larger orders are dispatched through freight forwarding partners. Delivery takes 7–10 business days, globally.
Always Delivered to Your Door
Every shipment is delivered directly to your address — regardless of country or carrier.
Our best-in-class warranties
3-Year Extended Warranty
Extended protection, enterprise-grade.
All enterprise hardware is backed by a 3-year warranty — triple the industry standard — covering defects under normal use.
Professional repairs & replacements.
If a hardware issue is confirmed, we’ll repair or replace the unit. Replacement parts carry either original or 3-month coverage.
RMA process, simplified.
Once an RMA is approved, return the defective unit within 10 days. We handle the rest — no service gaps.
Service Boundaries & Exclusions
What’s covered — and what’s best avoided.
Your warranty covers defects under normal use. For continued protection, avoid accidental damage, unauthorized repairs, third-party parts, or extreme environments.
Know your location’s service type.
In some regions, return-to-factory or remote service may apply. On-site service depends on infrastructure availability.
Minimal documentation required.
To initiate service, just submit the invoice and warranty card — no red tape, no waiting.
14-Day Money Back Guarantee
Free 14-Day Returns
Tested it, but it’s not a fit?
Return any product within 14 days of delivery if it doesn’t meet your technical or operational needs.
Initiate returns with ease.
Our RMA process is streamlined — just raise a request, follow the packaging guidelines, and we’ll handle the rest.
Refund or restock, your call.
Changed your mind? Get a refund (restocking fees may apply) or swap with another product.
30-Day Hardware Replacement
Covered for any early faults.
All equipment includes a 30-day replacement warranty. If something goes wrong, we’ll repair or swap it — fast.
Replacements shipped in 10 days or less.
Once your return is inspected and approved, we dispatch the replacement promptly to keep your operations moving.
RMA protocol keeps it smooth.
Just ensure all accessories and original packaging are intact — we’ll take care of the technical validation.
TRUSTED, TRIED, PROVEN
P14280-B21 Overview
P14280-B21 is a high-performance rackmount server engineered with support for Intel Xeon Scalable processors on an LGA 4189 socket, offering 2P CPU scalability to meet demanding workloads. It comes equipped with ECC DDR4 memory up to 512 GB across 8 slots, 4 PCIe 4.0 expansion slots, and 10 3.5-inch drive bays featuring hot-swap capability and RAID 10 support for reliable storage.
P14280-B21 also features dual redundant 750W power supplies and active cooling to maintain optimal operating temperatures in intensive data center environments. Integrated 1GbE network interfaces with 2 LAN ports, remote management via iDRAC, and official support for Windows Server and VMware ESXi make this server ideally suited for virtualization, file serving, and application hosting use cases.
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P14280-B21 Specifications
| Product Type | Server |
| Form Factor | Rackmount |
| Rack Units | 2U |
| Processor Brand | Intel |
| Processor Series | Intel Xeon Scalable |
| Processor Generation | Xeon 3rd Gen |
| Use Case | Virtualization |
| CPU Socket | LGA 4189 |
| Scalability | 2P |
| Max Cores Per CPU | 32 |
| Max Threads Per CPU | 64 |
| RAM Type | ECC DDR4 |
| RAM Slots | 8 |
| Max RAM Capacity | 512 GB |
| Storage Type | SATA HDD |
| Storage Bays | 10 |
| Drive Bay Size | 3.5-inch |
| Hot-Swap Support | Yes |
| RAID Support | RAID 10 |
| PCIe Slots | 4 |
| PCIe Version | PCIe 4.0 |
| Network Interface | 1GbE |
| LAN Ports | 2 |
| Remote Management | iDRAC |
| Power Supply | Redundant |
| Power Supply Wattage | 750W |
| Cooling | Active |
| Operating System | Windows Server |
| Virtualization Ready | Yes |
| GPU Support | No |
| Rail Kit Included | N/A |
| Product Name | P14280-B21 |
| Height | 3.5 inches |
| Width | 17.2 inches |
| Depth | 28.0 inches |
| Weight | 50 lbs |
P14280-B21 Use Case
Enterprise Virtualization and Workload Consolidation
In a global enterprise data center, IT architects deploy the P14280-B21-HPE ProLiant DL385 Gen10 Plus 12 LFF CTO Server to run VMware vSphere and Hyper-V clusters. Leveraging dual AMD EPYC™ processors and 12 LFF bays for flexible storage tiers, this solution consolidates 50+ virtual machines per node, cuts hardware sprawl by 70%, and lowers total cost of ownership through improved resource utilization and centralized management.
High-Performance Database and ERP Infrastructure
A financial services firm implements the P14280-B21-HPE ProLiant DL385 Gen10 Plus 12 LFF CTO Server as its primary Oracle and SAP HANA platform. With sub-millisecond I/O response, up to 4 TB of memory, hardware root of trust and custom 12 LFF storage, the server delivers predictable transaction throughput, ensures 99.99% application availability and accelerates daily close by 40%.
Scalable Analytics, AI Inference and Big Data Processing
A research lab scales its AI training and inference pipelines on a cluster of P14280-B21-HPE ProLiant DL385 Gen10 Plus 12 LFF CTO Servers. Combining AMD EPYC cores, optional NVIDIA GPUs and up to 144 TB of direct-attached storage, the platform powers large-scale Hadoop and TensorFlow workloads, reducing model training time by 60% while maintaining secure data sovereignty and edge-ready deployment flexibility.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table
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| Cooling | Active | Active | Active | Active | Active |
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Depth | 28 | 28 inches | 28.0 inches | 28 inches | 28.0 inches |
| Drive Bay Size | 3.5-inch | 2.5-inch | 3.5-inch | 3.5-inch | 3.5-inch |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | Yes | Yes | No | Yes | No |
| Height | 3.5 | 3.5 inches | 3.5 inches | 3.5 inches | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 2 | 2 | 2 | 2 | 2 |
| Max Cores per CPU | 32 | 32 | 32 | 32 | 32 |
| Max RAM Capacity | 1 TB | 512 GB | 512 GB | 512 GB | 2 TB |
| Max Threads per CPU | 64 | 64 | 64 | 64 | 64 |
| Network Interface | 10GbE | 10GbE | 1GbE | 10GbE | 10GbE |
| Operating System | Windows Server / VMware ESXi / Ubuntu | Windows Server | Windows Server | Windows Server / VMware ESXi / Ubuntu | Windows Server |
| PCIe Slots | 4 | 6 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 800W | 750W | 750W | 800W | 750W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 4th Gen | Xeon 4th Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | P07594-B21 | P14278-B21 | P14280-B21 | P14281-B21 High-Performance Rackmount Server | P14279-B21 |
| Product Type | Server | Server | Server | Server | Server |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| RAID Support | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 10 | RAID 10 | RAID 5 / RAID 10 | RAID 0/1/5/10 |
| Rail Kit Included | N/A | N/A | N/A | Yes | Yes |
| RAM Slots | 16 | 8 | 8 | 16 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 8 | 10 | 8 | 8 |
| Storage Type | SATA HDD | SATA SSD | SATA HDD | SATA SSD | SATA SSD |
| Use Case | Virtualization / File Server / Application Server | Virtualization | Virtualization | Virtualization / File Server / Application Server | Virtualization |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 35 lbs | 45 lbs | 50 lbs | 75 lbs | 45 lbs |
| Width | 17 | 17.3 inches | 17.2 inches | 17.5 inches | 17.3 inches |
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Questions & Answers
Q
What are the key specifications of the HPE ProLiant DL385 Gen10 Plus 12 LFF CTO Server?
A
The HPE ProLiant DL385 Gen10 Plus CTO features dual AMD EPYC processors, up to 4 TB DDR4 memory, 12 LFF drive bays, HPE Smart Array controller, flexible networking via FlexibleLOM, and HPE Integrated Lights-Out (iLO) 5 management.
Q
Which processors does the HPE ProLiant DL385 Gen10 Plus support?
A
It supports dual AMD EPYC 7002 and 7003 Series CPUs with up to 64 cores per socket, delivering high-performance compute for demanding workloads.
Q
What is the maximum memory capacity and type supported?
A
The server supports up to 4 TB of DDR4 SmartMemory across 16 DIMM slots, with speeds up to 3200 MT/s to optimize performance and reliability.
Q
How many drive bays does this server offer and what drive types can be installed?
A
It offers 12 large form factor (3.5") bays supporting SAS, SATA, and NVMe drives, enabling flexible and high-capacity storage configurations.
Q
Which storage controllers are available on the HPE ProLiant DL385 Gen10 Plus 12 LFF CTO?
A
Available options include HPE Smart Array P408i-a, P408e, and Ultra320 SCSI controllers providing RAID 0/1/5/6/10 support for data protection.
Q
What network connectivity options are supported?
A
Standard connectivity includes two embedded 1 GbE ports, with up to six FlexibleLOM or mezzanine slots supporting 10/25/100 GbE adapters for scalable networking.
Q
Does this server support GPU acceleration?
A
Yes, the DL385 Gen10 Plus can accommodate up to three double-wide or six single-wide GPUs via two PCIe 4.0 x16 slots for AI and HPC workloads.
Q
What management tools are included with the HPE ProLiant DL385 Gen10 Plus CTO?
A
It includes HPE Integrated Lights-Out (iLO) 5 for remote management, HPE InfoSight for AI-driven insights, and HPE OneView for unified infrastructure control.
Q
Is the HPE ProLiant DL385 Gen10 Plus compatible with major virtualization platforms?
A
Yes, it is certified for VMware vSphere, Microsoft Hyper-V, Red Hat Virtualization, and Nutanix AHV, ensuring broad virtualization support.
Q
Which operating systems are supported on this server?
A
Supported operating systems include Microsoft Windows Server, Red Hat Enterprise Linux, SUSE Linux Enterprise Server, Ubuntu Server, and VMware ESXi.
Q
What are the power efficiency and typical power consumption levels?
A
Powered by HPE Platinum efficiency power supplies (up to 94%), the server consumes approximately 350–600 W under full load, optimizing TCO.
Q
What form factor and physical dimensions does the server have?
A
It is a 2U rack server measuring 86.8 mm x 447 mm x 737 mm (H x W x D) and weighs up to 33 kg fully configured.
Q
What warranty and support options are available?
A
The server includes a standard 3-year HPE hardware warranty with optional HPE Foundation Care, Proactive Care, and Datacenter Care service upgrades.
Q
How does the HPE ProLiant DL385 Gen10 Plus address security and encryption?
A
It features Silicon Root of Trust, Secure Boot, runtime firmware validation, and supports optional HPE Self-Encrypting Drives (SEDs) for data protection.
Q
Can I customize the server configuration at purchase?
A
Yes, the CTO model allows customization of processors, memory, storage, networking, GPU options, and power supplies during ordering.
Q
What are common use cases and workloads for this server?
A
Ideal for virtualization, database management, high-performance computing, software-defined storage, AI inference, and edge computing.
Q
What cooling and acoustic levels should I expect?
A
It uses hot-plug redundant fans with N+1 configuration; typical acoustic noise is around 62 dB(A) at idle per ISO 7779 standards.
