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Balanced configuration suitable for mixed workloads.
P05887-B21
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HPE ProLiant DL385 Gen10 7251 2.1GHz 8-core 1P 16GB-R P408i-...
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P05887-B21
- Description:
- HPE ProLiant DL385 Gen10 7251 2.1GHz 8-core 1P 16GB-R P408i-a 8SFF 500W RPS Solution Server
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P05887-B21 Overview
P05887-B21 is a rackmount server engineered to support high-performance Intel Xeon Scalable processors on an LGA 4189 socket. Designed for dual processor (2P) scalability, the server is equipped with ECC DDR4 memory technology across 32 slots with a maximum capacity of 1 TB, and it features four high-speed PCIe 4.0 expansion slots. The system also includes 12 hot-swappable 2.5-inch storage bays with RAID 5 support to ensure data redundancy and performance.
P05887-B21 delivers robust networking with 10GbE interfaces across four LAN ports and is powered by redundant 800W power supplies that help maintain continuous operation. Active cooling and integrated iDRAC remote management ensure optimal thermal performance and ease of maintenance. Certified for operating environments such as Windows Server and VMware ESXi, this server is ideal for data centers, virtualization infrastructures, file servers, and application servers.
P05887-B21 price is is available on request. Get immediate quote.
Request bulk order quote for P05887-B21 for additional pricing. Browse the full Hpe Proliant Dl385 Gen10 Servers series or explore all Hpe products.
P05887-B21 Specifications
- Product Type
- Server
- Form Factor
- Rackmount
- Rack Units
- 2U
- Processor Brand
- Intel
- Processor Series
- Intel Xeon Scalable
- Processor Generation
- Xeon 3rd Gen
- Use Case
- Virtualization
- CPU Socket
- LGA 4189
- Scalability
- 2P
- Max Cores per CPU
- 32
- Max Threads per CPU
- 64
- RAM Type
- ECC DDR4
- RAM Slots
- 32
- Max RAM Capacity
- 1 TB
- Storage Type
- SATA SSD
- Storage Bays
- 12
- Drive Bay Size
- 2.5-inch
- Hot-Swap Support
- Yes
- RAID Support
- RAID 5
- PCIe Slots
- 4
- PCIe Version
- PCIe 4.0
- Network Interface
- 10GbE
- LAN Ports
- 4
- Remote Management
- iDRAC
- Power Supply
- Redundant
- Power Supply Wattage
- 800W
- Cooling
- Active
- Operating System
- Windows Server
- Virtualization Ready
- Yes
- GPU Support
- No
- Rail Kit Included
- Yes
- Product Name
- P05887-B21 Enterprise Rackmount Server
- Height
- 3.5 inches
- Width
- 17.5 inches
- Depth
- 28 inches
- Weight
- 60 lbs
P05887-B21 Use Case
Virtualization Consolidation for SMB Infrastructure
A mid-sized professional services firm deploys the P05887-B21 HPE ProLiant DL385 Gen10 7251 2.1 GHz 8-core 1P 16 GB-R P408i-a 8SFF 500 W RPS Solution Server as a VMware ESXi host, consolidating five legacy physical servers into a two-node cluster. By leveraging AMD EPYC cores and the onboard P408i-a RAID controller, the IT team reduces rack footprint by 60%, cuts power consumption by 30%, and accelerates VM provisioning by 40%. Outcome: streamlined management, scalable compute capacity, and a 20% reduction in total cost of ownership (TCO).
High-Performance OLTP Database for Financial Services
A regional financial institution selects the P05887-B21 HPE ProLiant DL385 Gen10 7251 2.1 GHz 8-core 1P 16 GB-R P408i-a 8SFF 500 W RPS Solution Server as its primary SQL Server node to process over 1 million transactions per hour. The combination of AMD EPYC 7251 processors, 16 GB RAM, and Intel NVMe SSDs in the 8SFF bays ensures sub-5 ms I/O latency. Outcome: 50% faster transaction throughput, 99.99% system availability, and audit-ready data integrity.
Edge-Compute and Remote Office Deployment for Retail
A national retail chain deploys the P05887-B21 HPE ProLiant DL385 Gen10 7251 2.1 GHz 8-core 1P 16 GB-R P408i-a 8SFF 500 W RPS Solution Server at 50 branch locations to host point-of-sale, local caching, and on-site backups. The robust 500 W redundant power supplies and eight hot-swap SFF bays store critical data on high-end SSDs, while HPE iLO enables centralized monitoring. Outcome: 100% POS uptime, 60% faster inventory lookups, and simplified remote management.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table 
| P05887-B21 |  878714-B21 |  P00323-S01 |  P09708-B21 |  P11747-B21 | |
|---|---|---|---|---|---|
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Cooling | Active | Active | Active | Active | Active |
| Depth | 28 inches | 28 inches | 28.0 inches | 28 inches | 28.5 inches |
| Drive Bay Size | 2.5-inch | 2.5-inch | 2.5-inch | Mixed | Mixed |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | No | Yes | No | Yes | No |
| Height | 3.5 inches | 3.5 inches | 3.5 inches | 3.5 inches | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 4 | 2 | 4 | 4 | 4 |
| Max Cores per CPU | 32 | 32 | 32 | 32 | 32 |
| Max RAM Capacity | 1 TB | 1 TB | 512 GB | 1 TB | 2 TB |
| Max Threads per CPU | 64 | 64 | 64 | 64 | 64 |
| Network Interface | 10GbE | 10GbE | 1GbE | 10GbE | 10GbE |
| Operating System | Windows Server | Windows Server | Windows Server | VMware ESXi | VMware ESXi |
| PCIe Slots | 4 | 4 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 800W | 1000W | 750W | 1000W | 750W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | P05887-B21 Enterprise Rackmount Server | 878714-B21 | P00323-S01 High Performance Rackmount Server | P09708-B21 Enterprise Rackmount Server | P11747-B21 |
| Product Type | Server | Server | Server | Server | Server |
| RAID Support | RAID 5 | RAID 5 | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 10 | RAID 10 |
| RAM Slots | 32 | 16 | 16 | 16 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| Rail Kit Included | Yes | N/A | Yes | Yes | N/A |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 12 | 8 | 8 | 8 | 12 |
| Storage Type | SATA SSD | SATA SSD | SATA SSD | NVMe SSD | Hybrid |
| Use Case | Virtualization | Virtualization / File Server / Application Server | Virtualization | Virtualization | Virtualization |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 60 lbs | 45 lbs | 45 lbs | 50 lbs | 45 lbs |
| Width | 17.5 inches | 19 inches | 17.0 inches | 17.5 inches | 17.3 inches |
Reviews & Ratings
B
Bilal Zafar
4
Easy setup with reliable RAID performance.
R
Remy Laurent
4
Consistent throughput and low maintenance.
O
Oliver Shaw
4
Good value for solution deployments.
F
Fahad Iqbal
5
Meets enterprise stability needs.
Questions & Answers
What processor does the HPE ProLiant DL385 Gen10 P05887-B21 include?
The server is equipped with a single AMD EPYC 7251 2.1 GHz 8-core processor for balanced performance and efficiency.
How much memory is pre-installed in this server?
It ships with 16 GB of DDR4 RDIMM memory, providing reliable baseline capacity for virtualization and database workloads.
How many drive bays does the server support and what types of drives are compatible?
It features eight hot-plug SFF drive bays compatible with SAS, SATA, and NVMe SSDs or HDDs for flexible storage configurations.
What RAID controller is included with the P05887-B21 configuration?
The HPE Smart Array P408i-a controller with 2 GB battery-backed cache delivers hardware RAID levels 0, 1, 5, 6, 10, 50, and 60.
What power supply does the HPE ProLiant DL385 Gen10 use?
A 500 W hot-plug redundant power supply provides high availability and allows maintenance without downtime.
What is the form factor of this server?
This is a 2U rack-mount server designed for data center and enterprise environments.
Which management tools are integrated into this server?
Integrated HPE iLO 5 offers remote management, monitoring, and lifecycle automation through an intuitive web interface.
Which operating systems are supported by the DL385 Gen10?
It supports major OS platforms including Windows Server, Red Hat Enterprise Linux, SUSE Linux Enterprise Server, Ubuntu, and VMware ESXi.
Is this server suitable for virtualization environments?
Yes, its multi-core AMD EPYC processor and large memory capacity make it ideal for virtual machines and hypervisor deployments.
What expansion options are available?
Three PCIe 3.0 expansion slots enable additional network, storage, or accelerator cards to meet growing workload demands.
What network connectivity options are built in?
It includes two onboard 1 Gb Ethernet ports and supports optional Flexible LOM or PCIe network adapters up to 100 Gb.
What warranty and support options are available?
The server comes with a standard 3-year parts, labor, and onsite warranty, with upgradeable support packages for enhanced service levels.
How energy efficient is the HPE ProLiant DL385 Gen10?
With platinum efficiency power supplies and advanced thermal design, it delivers optimized performance-per-watt and reduces data center costs.
What are the typical use cases for this server model?
It is ideal for database management, virtualization, big data analytics, VDI, and high-performance computing workloads.
How does the server ensure data protection?
Data protection is ensured through hardware RAID support, integrated TPM 2.0, Secure Boot, and proactive monitoring via iLO 5.
Can the memory and storage be upgraded?
Yes, memory can scale up to 1.5 TB using RDIMMs or LRDIMMs, and storage can be expanded with additional SAS, SATA, or NVMe drives in available bays.
How does the P05887-B21 configuration differ from other DL385 Gen10 models?
This configuration pairs the AMD EPYC 7251 CPU with the P408i-a RAID controller, 16 GB memory, and eight SFF bays, distinguishing it with balanced baseline performance and storage flexibility.