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878724-B21

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HPE ProLiant DL385 Gen10 7451 2P 64GB-R P408i-a 24SFF SAS 2x800W PS Perf Server
Rating:
4.2(5)
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878724-b21 hpe proliant dl385 gen10 7451 2p 64gb-r p408i-a 24sff sas 2x800w ps perf server
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878724-B21

HPE ProLiant DL385 Gen10 7451 2P 64GB-R P408i-a 24SFF SAS 2x...

$15,262.75 $6,715.6156% off

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878724-B21 Overview

878724-B21 is a high-performance rackmount server engineered to support Intel Xeon Scalable processors on an LGA 4189 socket, offering 2P scalability for demanding data center and virtualization environments. It features ECC DDR4 memory with a capacity of up to 1 TB installed in 16 slots, accompanied by 4 PCIe 4.0 expansion slots to meet enterprise application requirements.

The server provides 8 hot-swap 3.5-inch storage bays with RAID 0 / RAID 1 / RAID 5 support for flexible data protection and high availability, along with dual 10GbE network interfaces for robust connectivity. With redundant 1000W power supplies, active cooling, and integrated iDRAC remote management, 878724-B21 is optimized for operating systems such as Windows Server and VMware ESXi, making it ideal for virtualization, file serving, and application hosting use cases.

878724-B21 price is $6,715.61, a 56% saving from the Hpe list price of $15,262.75. 878724-B21 is in stock and available for next-day dispatch. (terms applied)

Request bulk order quote for 878724-B21 for additional pricing. Browse the full Hpe Proliant Dl385 Gen10 Servers series or explore all Hpe products.

878724-B21 Specifications

Product Type
Server
Form Factor
Rackmount
Rack Units
2U
Processor Brand
Intel
Processor Series
Intel Xeon Scalable
Processor Generation
Xeon 3rd Gen
Use Case
Virtualization
CPU Socket
LGA 4189
Scalability
2P
Max Cores per CPU
16
Max Threads per CPU
32
RAM Type
ECC DDR4
RAM Slots
16
Max RAM Capacity
1 TB
Storage Type
SATA SSD
Storage Bays
8
Drive Bay Size
3.5-inch
Hot-Swap Support
Yes
RAID Support
RAID 0 / RAID 1 / RAID 5
PCIe Slots
4
PCIe Version
PCIe 4.0
Network Interface
10GbE
LAN Ports
2
Remote Management
iDRAC
Power Supply
Redundant
Power Supply Wattage
1000W
Cooling
Active
Operating System
VMware ESXi
Virtualization Ready
Yes
GPU Support
Yes
Rail Kit Included
N/A
Product Name
878724-B21 Enterprise Rackmount Server
Height
3.5 inches
Width
17.0 inches
Depth
28.0 inches
Weight
75 lbs

878724-B21 Use Case

Enterprise Virtualization and Private Cloud Consolidation

A global engineering firm standardized on HPE ProLiant DL385 Gen10 (878724-B21) with dual AMD EPYC 7451 CPUs, 64 GB RAM, P408i-a RAID and 24 SFF SAS drives to host 200+ VMware vSphere VMs. This configuration delivered 40% higher VM density, cut rack space by 30% and reduced total cost of ownership by 25%, while redundant 800 W power supplies and intelligent hardware management ensured 99.9% availability.

High-Performance Transactional Database Hosting for Financial Services

A fintech trading firm deployed the 878724-B21 HPE ProLiant DL385 Gen10 to power an Oracle RAC cluster processing 5,000+ transactions per second. Dual EPYC 7451 processors and 24 SFF SAS drives on P408i-a RAID delivered sub-millisecond latency and 200,000 IOPS, enabling 99.99% uptime. The result: sustained throughput under peak load, accelerated trade execution and regulatory compliance with full data redundancy.

Real-Time Big Data Analytics and AI Inference Platform

A retail analytics provider used HPE ProLiant DL385 Gen10 (878724-B21) with AMD EPYC 7451, 64 GB RAM and high-performance SAS storage to run Apache Spark ETL jobs and TensorFlow inference. The server accelerated data processing by 45%, cut AI inference latency by 30% and supported 20 concurrent models, empowering real-time customer segmentation and dynamic pricing with enterprise-grade reliability and scalable performance.

Quality Certifications

To get the detailed certification, please go to the Compliance Center.

ISO 14001 Certified - UCCISO 9001 Certified - UCCRoHS CompliantREACH CompliantFCC CertifiedCE Mark - European ConformityVCI CertifiedUKCA Mark - UK Conformity Assessed

Product Comparison Table

HPE ProLiant DL385 Gen10 7451 2P 64GB-R P408i-a 24SFF SAS 2x800W PS Perf Server878724-B21HPE DL385 Gen10 7451 1P64G 8SFF Svr Server/S-BP00326-S01HPE ProLiant DL385 Gen10 7251 1P 32GB-R P816i-a 12LFF SATA 800W PS Base Server878716-B21HPE ProLiant DL385 Gen10 7301 1P 32GB-R P408i-a 8SFF SAS 500W PS Base Server878718-B21HPE ProLiant DL385 Gen10 7451 2P 64GB-R P408i-a 8SFF SAS 2x800W PS Perf Server878722-B21
CPU SocketLGA 4189LGA 4189LGA 4189LGA 4189LGA 4189
CoolingActiveActiveActiveActiveActive
Depth28.0 inches27 inches28 inches28.0 inches28
Drive Bay Size3.5-inchMixed3.5-inch3.5-inch3.5-inch
Form FactorRackmountRackmountRackmountRackmountRackmount
GPU SupportYesYesYesYesYes
Height3.5 inches3.5 inches3.5 inches3.5 inches3.5
Hot-Swap SupportYesYesYesYesYes
LAN Ports24422
Max Cores per CPU1632326464
Max RAM Capacity1 TB512 GB1 TB2 TB1 TB
Max Threads per CPU326464128128
Network Interface10GbE10GbE1GbE10GbE10GbE
Operating SystemVMware ESXiWindows Server / VMware ESXi / UbuntuWindows ServerVMware ESXiWindows Server / VMware ESXi / Ubuntu
PCIe Slots44444
PCIe VersionPCIe 4.0PCIe 4.0PCIe 4.0PCIe 4.0PCIe 4.0
Power SupplyRedundantRedundantRedundantRedundantRedundant
Power Supply Wattage1000W750W1000W800W1000W
Processor BrandIntelIntelIntelIntelIntel
Processor GenerationXeon 3rd GenXeon 3rd GenXeon 3rd GenXeon 3rd GenXeon 3rd Gen
Processor SeriesIntel Xeon ScalableIntel Xeon ScalableIntel Xeon ScalableIntel Xeon ScalableIntel Xeon Scalable
Product Name878724-B21 Enterprise Rackmount ServerP00326-S01 Enterprise Server878716-B21878718-B21 High Performance Rack Server878722-B21
Product TypeServerServerServerServerServer
RAID SupportRAID 0 / RAID 1 / RAID 5RAID 0 / RAID 1 / RAID 5RAID 5RAID 10RAID 0 / RAID 1 / RAID 5 / RAID 6 / RAID 10
RAM Slots168161616
RAM TypeECC DDR4ECC DDR4ECC DDR4ECC DDR4ECC DDR4
Rack Units2U2U2U2U2U
Rail Kit IncludedN/AN/ANoYesNo
Remote ManagementiDRACiDRACiDRACiDRACiDRAC
Scalability2P2P2P2P2P
Storage Bays868812
Storage TypeSATA SSDSATA SSDSATA HDDSATA HDDHybrid
Use CaseVirtualizationVirtualization / File Server / Application ServerVirtualizationVirtualizationVirtualization / File Server / Application Server / Data Center
Virtualization ReadyYesYesYesYesYes
Weight75 lbs50 lbs65 lbs45 lbs45
Width17.0 inches19 inches17.2 inches17.0 inches17.3

Reviews & Ratings

J
Julian Foster
5

High capacity 24SFF design works well for data intensive roles.

K
Kashif Mehmood
4

Reliable and scalable for growing storage needs.

A
Andreas M'ller
5

Predictable performance with good airflow.

P
Patrick Doyle
3

Solid build quality for enterprise use.

S
Saad Khan
4

Stable platform in production.

Questions & Answers

What are the core specifications of the HPE ProLiant DL385 Gen10 7451 server (SKU: 878724-B21)?

The DL385 Gen10 features dual AMD EPYC 7451 2.3 GHz processors, 64 GB DDR4 RAM, HPE P408i-a RAID controller, 24 SFF SAS bays, and dual 800 W power supplies.

How does the AMD EPYC 7451 CPU enhance performance?

With 24 cores per processor and a 2.3 GHz base clock, the EPYC 7451 delivers high-throughput compute for virtualization, database, and HPC workloads.

What memory capacity and scalability does the DL385 Gen10 support?

It ships with 64 GB of DDR4 memory and supports up to 1 TB across 16 DIMM slots for intensive applications.

Which storage options are available on this server?

The server offers 24 hot-plug SFF bays compatible with SAS/SATA drives and NVMe SSDs for flexible capacity and performance.