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878724-B21
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- HPE ProLiant DL385 Gen10 7451 2P 64GB-R P408i-a 24SFF SAS 2x800W PS Perf Server
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878724-B21
HPE ProLiant DL385 Gen10 7451 2P 64GB-R P408i-a 24...
$6,715.61
44 in Global Warehouse
$6,715.61
56% off
TRUSTED, TRIED, PROVEN
878724-B21 Overview
878724-B21 is a high-performance rackmount server engineered to support Intel Xeon Scalable processors on an LGA 4189 socket, offering 2P scalability for demanding data center and virtualization environments. It features ECC DDR4 memory with a capacity of up to 1 TB installed in 16 slots, accompanied by 4 PCIe 4.0 expansion slots to meet enterprise application requirements.
The server provides 8 hot-swap 3.5-inch storage bays with RAID 0 / RAID 1 / RAID 5 support for flexible data protection and high availability, along with dual 10GbE network interfaces for robust connectivity. With redundant 1000W power supplies, active cooling, and integrated iDRAC remote management, 878724-B21 is optimized for operating systems such as Windows Server and VMware ESXi, making it ideal for virtualization, file serving, and application hosting use cases.
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878724-B21 Specifications
| Product Type | Server |
| Form Factor | Rackmount |
| Rack Units | 2U |
| Processor Brand | Intel |
| Processor Series | Intel Xeon Scalable |
| Processor Generation | Xeon 3rd Gen |
| Use Case | Virtualization |
| CPU Socket | LGA 4189 |
| Scalability | 2P |
| Max Cores Per CPU | 16 |
| Max Threads Per CPU | 32 |
| RAM Type | ECC DDR4 |
| RAM Slots | 16 |
| Max RAM Capacity | 1 TB |
| Storage Type | SATA SSD |
| Storage Bays | 8 |
| Drive Bay Size | 3.5-inch |
| Hot-Swap Support | Yes |
| RAID Support | RAID 0 / RAID 1 / RAID 5 |
| PCIe Slots | 4 |
| PCIe Version | PCIe 4.0 |
| Network Interface | 10GbE |
| LAN Ports | 2 |
| Remote Management | iDRAC |
| Power Supply | Redundant |
| Power Supply Wattage | 1000W |
| Cooling | Active |
| Operating System | VMware ESXi |
| Virtualization Ready | Yes |
| GPU Support | Yes |
| Rail Kit Included | N/A |
| Product Name | 878724-B21 Enterprise Rackmount Server |
| Height | 3.5 inches |
| Width | 17.0 inches |
| Depth | 28.0 inches |
| Weight | 75 lbs |
878724-B21 Use Case
Enterprise Virtualization and Private Cloud Consolidation
A global engineering firm standardized on HPE ProLiant DL385 Gen10 (878724-B21) with dual AMD EPYC 7451 CPUs, 64 GB RAM, P408i-a RAID and 24 SFF SAS drives to host 200+ VMware vSphere VMs. This configuration delivered 40% higher VM density, cut rack space by 30% and reduced total cost of ownership by 25%, while redundant 800 W power supplies and intelligent hardware management ensured 99.9% availability.
High-Performance Transactional Database Hosting for Financial Services
A fintech trading firm deployed the 878724-B21 HPE ProLiant DL385 Gen10 to power an Oracle RAC cluster processing 5,000+ transactions per second. Dual EPYC 7451 processors and 24 SFF SAS drives on P408i-a RAID delivered sub-millisecond latency and 200,000 IOPS, enabling 99.99% uptime. The result: sustained throughput under peak load, accelerated trade execution and regulatory compliance with full data redundancy.
Real-Time Big Data Analytics and AI Inference Platform
A retail analytics provider used HPE ProLiant DL385 Gen10 (878724-B21) with AMD EPYC 7451, 64 GB RAM and high-performance SAS storage to run Apache Spark ETL jobs and TensorFlow inference. The server accelerated data processing by 45%, cut AI inference latency by 30% and supported 20 concurrent models, empowering real-time customer segmentation and dynamic pricing with enterprise-grade reliability and scalable performance.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table
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| Cooling | Active | Active | Active | Active | Active |
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Depth | 28.0 inches | 28 | 28.0 inches | 28 inches | 27 inches |
| Drive Bay Size | 3.5-inch | 3.5-inch | 3.5-inch | 3.5-inch | Mixed |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | Yes | Yes | Yes | Yes | Yes |
| Height | 3.5 inches | 3.5 | 3.5 inches | 3.5 inches | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 2 | 2 | 2 | 4 | 4 |
| Max Cores per CPU | 64 | 64 | 16 | 32 | 32 |
| Max RAM Capacity | 2 TB | 1 TB | 1 TB | 1 TB | 512 GB |
| Max Threads per CPU | 128 | 128 | 32 | 64 | 64 |
| Network Interface | 10GbE | 10GbE | 10GbE | 1GbE | 10GbE |
| Operating System | VMware ESXi | Windows Server / VMware ESXi / Ubuntu | VMware ESXi | Windows Server | Windows Server / VMware ESXi / Ubuntu |
| PCIe Slots | 4 | 4 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 800W | 1000W | 1000W | 1000W | 750W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | 878718-B21 High Performance Rack Server | 878722-B21 | 878724-B21 Enterprise Rackmount Server | 878716-B21 | P00326-S01 Enterprise Server |
| Product Type | Server | Server | Server | Server | Server |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| RAID Support | RAID 10 | RAID 0 / RAID 1 / RAID 5 / RAID 6 / RAID 10 | RAID 0 / RAID 1 / RAID 5 | RAID 5 | RAID 0 / RAID 1 / RAID 5 |
| Rail Kit Included | Yes | No | N/A | No | N/A |
| RAM Slots | 16 | 16 | 16 | 16 | 8 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 12 | 8 | 8 | 6 |
| Storage Type | SATA HDD | Hybrid | SATA SSD | SATA HDD | SATA SSD |
| Use Case | Virtualization | Virtualization / File Server / Application Server / Data Center | Virtualization | Virtualization | Virtualization / File Server / Application Server |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 45 lbs | 45 | 75 lbs | 65 lbs | 50 lbs |
| Width | 17.0 inches | 17.3 | 17.0 inches | 17.2 inches | 19 inches |
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Questions & Answers
Q
What are the core specifications of the HPE ProLiant DL385 Gen10 7451 server (SKU: 878724-B21)?
A
The DL385 Gen10 features dual AMD EPYC 7451 2.3 GHz processors, 64 GB DDR4 RAM, HPE P408i-a RAID controller, 24 SFF SAS bays, and dual 800 W power supplies.
Q
How does the AMD EPYC 7451 CPU enhance performance?
A
With 24 cores per processor and a 2.3 GHz base clock, the EPYC 7451 delivers high-throughput compute for virtualization, database, and HPC workloads.
Q
What memory capacity and scalability does the DL385 Gen10 support?
A
It ships with 64 GB of DDR4 memory and supports up to 1 TB across 16 DIMM slots for intensive applications.
Q
Which storage options are available on this server?
A
The server offers 24 hot-plug SFF bays compatible with SAS/SATA drives and NVMe SSDs for flexible capacity and performance.
Q
What RAID levels does the HPE P408i-a controller support?
A
The P408i-a supports RAID 0, 1, 10, 5, 50, 6, and 60, enabling balanced data protection and performance.
Q
How redundant are the power supplies?
A
It includes two hot-swappable 800 W Platinum efficiency power supplies with N+1 redundancy for high availability.
Q
Which management tools come integrated with this server?
A
HPE Integrated Lights-Out (iLO 5) provides remote management, firmware updates, health monitoring, and agentless convergence.
Q
Is the DL385 Gen10 optimized for virtualization?
A
Yes, its high core count, large memory capacity, and virtualization-ready drivers make it ideal for VMware, Hyper-V, and KVM environments.
Q
What operating systems are officially supported?
A
HPE certifies Windows Server, various Linux distributions (RHEL, SUSE), VMware ESXi, and select virtualization stacks.
Q
Which workloads are best suited for this server?
A
It excels in database management, virtualization, analytics, HPC, and software-defined storage applications.
Q
How many expansion slots are available?
A
The chassis includes three PCIe 3.0 slots for additional NICs, HBAs, GPUs, or storage controllers.
Q
What networking options can I install?
A
You can add 1/10/25/40/100 GbE adapters via PCIe and utilize onboard FlexibleLOM slots for integrated network modules.
Q
Can I upgrade storage capacity later?
A
Yes, you can populate empty SFF bays, add NVMe modules, or attach external JBOD enclosures as needed.
Q
What GPU support does this server provide?
A
It supports up to two low-profile GPUs or one full-height GPU via available PCIe slots for AI and graphics acceleration.
Q
What warranty and support options are available?
A
HPE offers a standard 3-year parts, labor, and onsite warranty, with optional ProActive Care and Foundation Care services.
Q
How energy efficient is the DL385 Gen10?
A
Featuring high-efficiency power supplies, adaptive cooling, and silicon root of trust, it reduces energy consumption and operational costs.