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878724-B21
HPE ProLiant DL385 Gen10 7451 2P 64GB-R P408i-a 24SFF SAS 2x...
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878724-B21 is a high-performance rackmount server engineered to support Intel Xeon Scalable processors on an LGA 4189 socket, offering 2P scalability for demanding data center and virtualization environments. It features ECC DDR4 memory with a capacity of up to 1 TB installed in 16 slots, accompanied by 4 PCIe 4.0 expansion slots to meet enterprise application requirements.
The server provides 8 hot-swap 3.5-inch storage bays with RAID 0 / RAID 1 / RAID 5 support for flexible data protection and high availability, along with dual 10GbE network interfaces for robust connectivity. With redundant 1000W power supplies, active cooling, and integrated iDRAC remote management, 878724-B21 is optimized for operating systems such as Windows Server and VMware ESXi, making it ideal for virtualization, file serving, and application hosting use cases.
878724-B21 price is $6,715.61, a 56% saving from the Hpe list price of $15,262.75. 878724-B21 is in stock and available for next-day dispatch. (terms applied)
Request bulk order quote for 878724-B21 for additional pricing. Browse the full Hpe Proliant Dl385 Gen10 Servers series or explore all Hpe products.
A global engineering firm standardized on HPE ProLiant DL385 Gen10 (878724-B21) with dual AMD EPYC 7451 CPUs, 64 GB RAM, P408i-a RAID and 24 SFF SAS drives to host 200+ VMware vSphere VMs. This configuration delivered 40% higher VM density, cut rack space by 30% and reduced total cost of ownership by 25%, while redundant 800 W power supplies and intelligent hardware management ensured 99.9% availability.
A fintech trading firm deployed the 878724-B21 HPE ProLiant DL385 Gen10 to power an Oracle RAC cluster processing 5,000+ transactions per second. Dual EPYC 7451 processors and 24 SFF SAS drives on P408i-a RAID delivered sub-millisecond latency and 200,000 IOPS, enabling 99.99% uptime. The result: sustained throughput under peak load, accelerated trade execution and regulatory compliance with full data redundancy.
A retail analytics provider used HPE ProLiant DL385 Gen10 (878724-B21) with AMD EPYC 7451, 64 GB RAM and high-performance SAS storage to run Apache Spark ETL jobs and TensorFlow inference. The server accelerated data processing by 45%, cut AI inference latency by 30% and supported 20 concurrent models, empowering real-time customer segmentation and dynamic pricing with enterprise-grade reliability and scalable performance.
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| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Cooling | Active | Active | Active | Active | Active |
| Depth | 28.0 inches | 27 inches | 28 inches | 28.0 inches | 28 |
| Drive Bay Size | 3.5-inch | Mixed | 3.5-inch | 3.5-inch | 3.5-inch |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | Yes | Yes | Yes | Yes | Yes |
| Height | 3.5 inches | 3.5 inches | 3.5 inches | 3.5 inches | 3.5 |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 2 | 4 | 4 | 2 | 2 |
| Max Cores per CPU | 16 | 32 | 32 | 64 | 64 |
| Max RAM Capacity | 1 TB | 512 GB | 1 TB | 2 TB | 1 TB |
| Max Threads per CPU | 32 | 64 | 64 | 128 | 128 |
| Network Interface | 10GbE | 10GbE | 1GbE | 10GbE | 10GbE |
| Operating System | VMware ESXi | Windows Server / VMware ESXi / Ubuntu | Windows Server | VMware ESXi | Windows Server / VMware ESXi / Ubuntu |
| PCIe Slots | 4 | 4 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 1000W | 750W | 1000W | 800W | 1000W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | 878724-B21 Enterprise Rackmount Server | P00326-S01 Enterprise Server | 878716-B21 | 878718-B21 High Performance Rack Server | 878722-B21 |
| Product Type | Server | Server | Server | Server | Server |
| RAID Support | RAID 0 / RAID 1 / RAID 5 | RAID 0 / RAID 1 / RAID 5 | RAID 5 | RAID 10 | RAID 0 / RAID 1 / RAID 5 / RAID 6 / RAID 10 |
| RAM Slots | 16 | 8 | 16 | 16 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| Rail Kit Included | N/A | N/A | No | Yes | No |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 6 | 8 | 8 | 12 |
| Storage Type | SATA SSD | SATA SSD | SATA HDD | SATA HDD | Hybrid |
| Use Case | Virtualization | Virtualization / File Server / Application Server | Virtualization | Virtualization | Virtualization / File Server / Application Server / Data Center |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 75 lbs | 50 lbs | 65 lbs | 45 lbs | 45 |
| Width | 17.0 inches | 19 inches | 17.2 inches | 17.0 inches | 17.3 |
High capacity 24SFF design works well for data intensive roles.
Reliable and scalable for growing storage needs.
Predictable performance with good airflow.
Solid build quality for enterprise use.
Stable platform in production.
The DL385 Gen10 features dual AMD EPYC 7451 2.3 GHz processors, 64 GB DDR4 RAM, HPE P408i-a RAID controller, 24 SFF SAS bays, and dual 800 W power supplies.
With 24 cores per processor and a 2.3 GHz base clock, the EPYC 7451 delivers high-throughput compute for virtualization, database, and HPC workloads.
It ships with 64 GB of DDR4 memory and supports up to 1 TB across 16 DIMM slots for intensive applications.
The server offers 24 hot-plug SFF bays compatible with SAS/SATA drives and NVMe SSDs for flexible capacity and performance.