United States$5,000,000+
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T
Tom Ellison
5
12LFF TAA option works well for compliant storage builds.
878618-B21
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HPE DL385 Gen10 CTO Mod-X 12LFF TAA Svr Server
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878618-B21
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- HPE DL385 Gen10 CTO Mod-X 12LFF TAA Svr Server
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878618-B21 Overview
878618-B21 is a high-performance rackmount server engineered for data center, virtualization, file server, and application server environments. It supports Intel Xeon Scalable processors on an LGA 4189 socket with 2P scalability, enabling robust CPU performance with up to 32 cores and 64 threads per processor. The server is equipped with ECC DDR4 memory across 8 DIMM slots for a maximum capacity of 512 GB, features a mix of 2.5-inch and 3.5-inch drive bays with hot-swap support, and provides RAID 10 support to ensure data integrity.
The 878618-B21 is designed with four PCIe 4.0 expansion slots and dual 10GbE network interfaces for optimal connectivity. It includes redundant 800W power supplies with active cooling to maintain system reliability, and its integrated iDRAC remote management facilitates efficient monitoring and control. Certified for operating systems including Windows Server, this server meets the rigorous demands of virtualized and high-availability infrastructures.
878618-B21 price is is available on request. Get immediate quote.
Request bulk order quote for 878618-B21 for additional pricing. Browse the full Hpe Proliant Dl385 Gen10 Servers series or explore all Hpe products.
878618-B21 Specifications
- Width
- 17.5 inches
- Depth
- 28 inches
- Height
- 3.5 inches
- Weight
- 45 lbs
- Form Factor
- Rackmount
- PCIe Version
- PCIe 4.0
- RAID Support
- RAID 10
- CPU Socket
- LGA 4189
- Product Type
- Server
- Rack Units
- 2U
- Processor Brand
- Intel
- Processor Series
- Intel Xeon Scalable
- Use Case
- Virtualization
- Scalability
- 2P
- Max Cores per CPU
- 32
- Max Threads per CPU
- 64
- RAM Type
- ECC DDR4
- Storage Bays
- 8
- Drive Bay Size
- Mixed
- Hot-Swap Support
- Yes
- PCIe Slots
- 4
- Network Interface
- 10GbE
- LAN Ports
- 2
- Remote Management
- iDRAC
- Power Supply
- Redundant
- Cooling
- Active
- Virtualization Ready
- Yes
- GPU Support
- Yes
- Processor Generation
- Xeon 3rd Gen
- Max RAM Capacity
- 512 GB
- Power Supply Wattage
- 800W
- Rail Kit Included
- Yes
- Operating System
- Windows Server
- RAM Slots
- 8
- Storage Type
- SATA SSD
- Product Name
- 878618-B21 High Performance Rack Server
878618-B21 Use Case
Virtualization and Server Consolidation with 878618-B21 HPE DL385 Gen10 CTO Mod-X 12LFF TAA Svr Server
A mid-sized enterprise consolidates 20+ legacy physical servers onto the 878618-B21 HPE DL385 Gen10 CTO Mod-X 12LFF TAA Svr Server running VMware vSphere to host multi-tier applications. Benefit: achieves a 60% reduction in rack footprint, cuts power and cooling costs by 45%, and streamlines IT management while maintaining TAA compliance and enterprise-grade performance.
Real-Time In-Memory Analytics on SAP HANA with 878618-B21 HPE DL385 Gen10 CTO Mod-X 12LFF TAA Svr Server
A regional financial services firm deploys SAP HANA in-memory analytics on the 878618-B21 HPE DL385 Gen10 CTO Mod-X 12LFF TAA Svr Server to accelerate risk modeling, fraud detection, and regulatory reporting. Benefit: delivers sub-second query response times, scales to multi-TB datasets, and ensures 99.99% availability for mission-critical insights.
High-Performance E-commerce Transaction Processing on 878618-B21 HPE DL385 Gen10 CTO Mod-X 12LFF TAA Svr Server
A leading online retailer leverages the 878618-B21 HPE DL385 Gen10 CTO Mod-X 12LFF TAA Svr Server with NVMe storage to power Microsoft SQL and NoSQL clusters during peak shopping events. Benefit: sustains over 20,000 transactions per second, scales storage capacity to 5 PB, and maintains 99.99% uptime for seamless customer checkout experiences.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table 
| 878618-B21 |  878722-B21 |  878619-B21 |  878724-B21 |  P00325-S01 | |
|---|---|---|---|---|---|
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Cooling | Active | Active | Active | Active | Active |
| Depth | 28 inches | 28 | 28 inches | 28.0 inches | 30 inches |
| Drive Bay Size | Mixed | 3.5-inch | 3.5-inch | 3.5-inch | Mixed |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | Yes | Yes | Yes | Yes | No |
| Height | 3.5 inches | 3.5 | 3.5 inches | 3.5 inches | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 2 | 2 | 4 | 2 | 2 |
| Max Cores per CPU | 32 | 64 | 32 | 16 | 24 |
| Max RAM Capacity | 512 GB | 1 TB | 1 TB | 1 TB | 2 TB |
| Max Threads per CPU | 64 | 128 | 64 | 32 | 48 |
| Network Interface | 10GbE | 10GbE | 10GbE | 10GbE | 10GbE |
| Operating System | Windows Server | Windows Server / VMware ESXi / Ubuntu | Windows Server / VMware ESXi / Ubuntu | VMware ESXi | VMware ESXi |
| PCIe Slots | 4 | 4 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 800W | 1000W | 1000W | 1000W | 800W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 4th Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | 878618-B21 High Performance Rack Server | 878722-B21 | 878619-B21 Enterprise Rack Server | 878724-B21 Enterprise Rackmount Server | P00325-S01 Enterprise Rack Server |
| Product Type | Server | Server | Server | Server | Server |
| RAID Support | RAID 10 | RAID 0 / RAID 1 / RAID 5 / RAID 6 / RAID 10 | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 0 / RAID 1 / RAID 5 | RAID 10 |
| RAM Slots | 8 | 16 | 16 | 16 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| Rail Kit Included | Yes | No | Yes | N/A | Yes |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 12 | 8 | 8 | 8 |
| Storage Type | SATA SSD | Hybrid | SATA HDD | SATA SSD | SATA SSD |
| Use Case | Virtualization | Virtualization / File Server / Application Server / Data Center | Virtualization / File Server / Application Server | Virtualization | Virtualization |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 45 lbs | 45 | 50 lbs | 75 lbs | 75 lbs |
| Width | 17.5 inches | 17.3 | 17.2 inches | 17.0 inches | 17 inches |
Reviews & Ratings
M
Muneeb Raza
5
Reliable under daily operational load.
J
Jan Kowalski
5
Predictable airflow and performance.
H
Henry Moore
4
Good serviceability.
Z
Zubair Nawaz
5
Meets compliance and stability needs.
Questions & Answers
What is the HPE DL385 Gen10 CTO Mod-X 12LFF TAA Server (SKU: 878618-B21)?
The HPE DL385 Gen10 CTO Mod-X 12LFF TAA Server (SKU: 878618-B21) is a 2U rack-mount, TAA-compliant, configurable system featuring dual AMD EPYC CPUs, up to 12 large form-factor drives, advanced storage, networking options, and HPE iLO 5 management.
Which processors are supported in the HPE DL385 Gen10 CTO Mod-X 12LFF TAA Server?
This server supports dual 1st- and 2nd-generation AMD EPYC processors with up to 64 cores and 128 threads per CPU, delivering high performance for virtualization, database, and HPC workloads.
What is the maximum memory capacity of this HPE DL385 Gen10 server?
The system supports up to 4 TB of DDR4 SmartMemory across 16 DIMM slots, with speeds up to 3200 MT/s and HPE Persistent Memory options for in-memory compute acceleration.
How many and what type of drives does the HPE DL385 Gen10 CTO Mod-X server accommodate?
It provides 12 large form-factor (3.5") hot-plug drive bays supporting SAS, SATA, and NVMe HDD/SSDs, enabling high-capacity storage and flexible performance tiers.
What RAID and storage controller options are available?
Choose from HPE Smart Array controllers, including hardware RAID 0/1/5/6/10/50/60 with cache—to optimize performance and data protection—or software RAID for entry-level configurations.
How many PCIe expansion slots are included?
The server offers eight PCIe Gen4 slots (six full-height, full-length plus two low-profile) for GPUs, networking, storage accelerators, or additional controllers.
What networking capabilities does the HPE DL385 Gen10 CTO Mod-X server have?
Standard features include two 1 Gb Ethernet ports, with optional FlexibleLOM or PCIe adapters supporting 10/25/40/50/100 Gb Ethernet or InfiniBand for low-latency, high-bandwidth connectivity.
Which management tools are integrated into this server?
HPE iLO 5 provides agentless remote management, 24×7 firmware updates, automated deployment via HPE OneView, and HPE Insight Remote Support for proactive health monitoring.
What power supply options are supported?
Choose from redundant hot-plug Platinum or Titanium-level power supplies in 800 W, 1200 W, or 1600 W configurations, with load-sharing and efficiency up to 96%.
Is the HPE DL385 Gen10 CTO Mod-X server TAA compliant?
Yes. This model is Trade Agreements Act (TAA) compliant, ensuring procurement eligibility for U.S. government and federal agencies.
What are the ideal use cases for this server?
It excels in virtualized infrastructures, large-scale databases, in-memory analytics, HPC, cloud deployments, and software-defined storage environments.
How does the CTO (Configure-To-Order) feature work?
HPE’s CTO process lets you select CPUs, memory, storage, networking, and power supplies to match workload requirements, ensuring a tailored solution on delivery.
Which operating systems are supported on the HPE DL385 Gen10 CTO Mod-X server?
Certified OS options include Windows Server, Red Hat Enterprise Linux, SUSE Linux Enterprise Server, VMware ESXi, and major Linux distributions with optimized drivers.
What security features are included in this server?
Built-in security includes Silicon Root of Trust, TPM 2.0, secure boot, encrypted storage, runtime firmware validation, and HPE Secure Erase for data sanitization.
What is the server’s warranty and support guarantee?
It comes with a standard three-year HPE Warranty and 1 year of 24×7 parts, labor, and onsite support, upgradeable with HPE Pointnext Services.
What is the physical form factor and dimensions of this server?
The HPE DL385 Gen10 CTO Mod-X is a 2U rack server measuring 86 mm (H) × 447 mm (W) × 737 mm (D), suitable for data center racks, with front-to-back airflow.