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878618-B21
HPE DL385 Gen10 CTO Mod-X 12LFF TAA Svr Server
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878618-B21 is a high-performance rackmount server engineered for data center, virtualization, file server, and application server environments. It supports Intel Xeon Scalable processors on an LGA 4189 socket with 2P scalability, enabling robust CPU performance with up to 32 cores and 64 threads per processor. The server is equipped with ECC DDR4 memory across 8 DIMM slots for a maximum capacity of 512 GB, features a mix of 2.5-inch and 3.5-inch drive bays with hot-swap support, and provides RAID 10 support to ensure data integrity.
The 878618-B21 is designed with four PCIe 4.0 expansion slots and dual 10GbE network interfaces for optimal connectivity. It includes redundant 800W power supplies with active cooling to maintain system reliability, and its integrated iDRAC remote management facilitates efficient monitoring and control. Certified for operating systems including Windows Server, this server meets the rigorous demands of virtualized and high-availability infrastructures.
878618-B21 price is is available on request. Get immediate quote.
Request bulk order quote for 878618-B21 for additional pricing. Browse the full Hpe Proliant Dl385 Gen10 Servers series or explore all Hpe products.
A mid-sized enterprise consolidates 20+ legacy physical servers onto the 878618-B21 HPE DL385 Gen10 CTO Mod-X 12LFF TAA Svr Server running VMware vSphere to host multi-tier applications. Benefit: achieves a 60% reduction in rack footprint, cuts power and cooling costs by 45%, and streamlines IT management while maintaining TAA compliance and enterprise-grade performance.
A regional financial services firm deploys SAP HANA in-memory analytics on the 878618-B21 HPE DL385 Gen10 CTO Mod-X 12LFF TAA Svr Server to accelerate risk modeling, fraud detection, and regulatory reporting. Benefit: delivers sub-second query response times, scales to multi-TB datasets, and ensures 99.99% availability for mission-critical insights.
A leading online retailer leverages the 878618-B21 HPE DL385 Gen10 CTO Mod-X 12LFF TAA Svr Server with NVMe storage to power Microsoft SQL and NoSQL clusters during peak shopping events. Benefit: sustains over 20,000 transactions per second, scales storage capacity to 5 PB, and maintains 99.99% uptime for seamless customer checkout experiences.
To get the detailed certification, please go to the Compliance Center.
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Cooling | Active | Active | Active | Active | Active |
| Depth | 28 inches | 28 | 28 inches | 28.0 inches | 30 inches |
| Drive Bay Size | Mixed | 3.5-inch | 3.5-inch | 3.5-inch | Mixed |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | Yes | Yes | Yes | Yes | No |
| Height | 3.5 inches | 3.5 | 3.5 inches | 3.5 inches | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 2 | 2 | 4 | 2 | 2 |
| Max Cores per CPU | 32 | 64 | 32 | 16 | 24 |
| Max RAM Capacity | 512 GB | 1 TB | 1 TB | 1 TB | 2 TB |
| Max Threads per CPU | 64 | 128 | 64 | 32 | 48 |
| Network Interface | 10GbE | 10GbE | 10GbE | 10GbE | 10GbE |
| Operating System | Windows Server | Windows Server / VMware ESXi / Ubuntu | Windows Server / VMware ESXi / Ubuntu | VMware ESXi | VMware ESXi |
| PCIe Slots | 4 | 4 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 800W | 1000W | 1000W | 1000W | 800W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 4th Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | 878618-B21 High Performance Rack Server | 878722-B21 | 878619-B21 Enterprise Rack Server | 878724-B21 Enterprise Rackmount Server | P00325-S01 Enterprise Rack Server |
| Product Type | Server | Server | Server | Server | Server |
| RAID Support | RAID 10 | RAID 0 / RAID 1 / RAID 5 / RAID 6 / RAID 10 | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 0 / RAID 1 / RAID 5 | RAID 10 |
| RAM Slots | 8 | 16 | 16 | 16 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| Rail Kit Included | Yes | No | Yes | N/A | Yes |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 12 | 8 | 8 | 8 |
| Storage Type | SATA SSD | Hybrid | SATA HDD | SATA SSD | SATA SSD |
| Use Case | Virtualization | Virtualization / File Server / Application Server / Data Center | Virtualization / File Server / Application Server | Virtualization | Virtualization |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 45 lbs | 45 | 50 lbs | 75 lbs | 75 lbs |
| Width | 17.5 inches | 17.3 | 17.2 inches | 17.0 inches | 17 inches |
12LFF TAA option works well for compliant storage builds.
Reliable under daily operational load.
Predictable airflow and performance.
Good serviceability.
Meets compliance and stability needs.
The HPE DL385 Gen10 CTO Mod-X 12LFF TAA Server (SKU: 878618-B21) is a 2U rack-mount, TAA-compliant, configurable system featuring dual AMD EPYC CPUs, up to 12 large form-factor drives, advanced storage, networking options, and HPE iLO 5 management.
This server supports dual 1st- and 2nd-generation AMD EPYC processors with up to 64 cores and 128 threads per CPU, delivering high performance for virtualization, database, and HPC workloads.
The system supports up to 4 TB of DDR4 SmartMemory across 16 DIMM slots, with speeds up to 3200 MT/s and HPE Persistent Memory options for in-memory compute acceleration.
It provides 12 large form-factor (3.5") hot-plug drive bays supporting SAS, SATA, and NVMe HDD/SSDs, enabling high-capacity storage and flexible performance tiers.