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Flexible CTO chassis allows tailored configurations.
878613-B21
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HPE ProLiant DL385 Gen10 CTO Mod-X 24 Small Form Factor Serv...
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878613-B21
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- HPE ProLiant DL385 Gen10 CTO Mod-X 24 Small Form Factor Server
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878613-B21 Overview
878613-B21 is a rackmount server engineered for high-density data center environments and designed to support Intel Xeon Scalable processors on an LGA 4189 socket. It offers 2P CPU scalability, ECC DDR4 memory supporting up to 1 TB via 16 DIMM slots, 4 PCIe 4.0 expansion slots, and 8 hot-swappable 3.5-inch drive bays with RAID 5 support, ensuring reliable performance for virtualization and file serving applications.
878613-B21 comes equipped with redundant 800W power supplies, active cooling to maintain optimal operating temperatures, and iDRAC remote management for streamlined administration. Certified for Windows Server deployments, this server is ideally suited for data center operations, application hosting, and virtualization environments where robust performance and scalability are imperative.
878613-B21 price is is available on request. Get immediate quote.
Request bulk order quote for 878613-B21 for additional pricing. Browse the full Hpe Proliant Dl385 Gen10 Servers series or explore all Hpe products.
878613-B21 Specifications
- Width
- 17.2 inches
- Depth
- 28 inches
- Height
- 3.5 inches
- Weight
- 45 lbs
- Form Factor
- Rackmount
- PCIe Version
- PCIe 4.0
- CPU Socket
- LGA 4189
- Product Type
- Server
- Rack Units
- 2U
- Processor Brand
- Intel
- Processor Series
- Intel Xeon Scalable
- Scalability
- 2P
- Max Cores per CPU
- 32
- Max Threads per CPU
- 64
- RAM Type
- ECC DDR4
- RAM Slots
- 16
- Storage Type
- SATA HDD
- Storage Bays
- 8
- Hot-Swap Support
- Yes
- PCIe Slots
- 4
- Network Interface
- 10GbE
- Remote Management
- iDRAC
- Power Supply
- Redundant
- Cooling
- Active
- Virtualization Ready
- Yes
- Processor Generation
- Xeon 3rd Gen
- Power Supply Wattage
- 800W
- Rail Kit Included
- Yes
- Max RAM Capacity
- 1 TB
- Drive Bay Size
- 3.5-inch
- RAID Support
- RAID 5
- Operating System
- Windows Server
- GPU Support
- No
- LAN Ports
- 4
- Use Case
- Virtualization / File Server / Application Server
- Product Name
- 878613-B21
878613-B21 Use Case
Private Cloud Virtualization and Consolidation
Deploy the 878613-B21-HPE ProLiant DL385 Gen10 CTO Mod-X 24 SFF Server as a private cloud host with VMware vSphere or Red Hat OpenStack. Leveraging up to 64 AMD EPYC cores, 4 TB DDR4 memory, and HPE OneView automation, it consolidates 100+ VMs per node. Outcome: 70% rack-space reduction, 40% lower power draw, faster provisioning, and a streamlined ROI on compute infrastructure.
Enterprise VDI for Distributed Workforces
Implement large-scale virtual desktop infrastructure on the HPE ProLiant DL385 Gen10 CTO Mod-X server with 2 TB memory and NVMe storage. Certified for VMware Horizon and Citrix Virtual Apps, it delivers sub-20 ms login times for 150+ concurrent users. Outcome: enhanced end-user experience, centralized data security via HPE iLO, and a 50% cut in desktop lifecycle management costs.
Edge AI Inference and Real-Time Analytics
Use the 878613-B21 HPE ProLiant DL385 Gen10 CTO Mod-X 24 SFF Server at the edge with PCIe Gen4 acceleration cards and NVMe SSDs for AI/ML workloads. Process high-resolution video streams or sensor data with sub-1 ms latency in retail or manufacturing environments. Outcome: real-time decisioning, 30% faster inference, optimized supply chain operations, and secure remote management via HPE iLO.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table 
| 878613-B21 |  878615-B21 |  878716-B21 |  878722-B21 |  P11747-B21 | |
|---|---|---|---|---|---|
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Cooling | Active | Active | Active | Active | Active |
| Depth | 28 inches | 27.6 inches | 28 inches | 28 | 28.5 inches |
| Drive Bay Size | 3.5-inch | 3.5-inch | 3.5-inch | 3.5-inch | Mixed |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | No | Yes | Yes | Yes | No |
| Height | 3.5 inches | 3.44 inches | 3.5 inches | 3.5 | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 4 | 2 | 4 | 2 | 4 |
| Max Cores per CPU | 32 | 32 | 32 | 64 | 32 |
| Max RAM Capacity | 1 TB | 512 GB | 1 TB | 1 TB | 2 TB |
| Max Threads per CPU | 64 | 64 | 64 | 128 | 64 |
| Network Interface | 10GbE | 1GbE | 1GbE | 10GbE | 10GbE |
| Operating System | Windows Server | Windows Server / VMware ESXi / Ubuntu / RHEL | Windows Server | Windows Server / VMware ESXi / Ubuntu | VMware ESXi |
| PCIe Slots | 4 | 4 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 800W | 750W | 1000W | 1000W | 750W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | 878613-B21 | 878615-B21 | 878716-B21 | 878722-B21 | P11747-B21 |
| Product Type | Server | Server | Server | Server | Server |
| RAID Support | RAID 5 | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 5 | RAID 0 / RAID 1 / RAID 5 / RAID 6 / RAID 10 | RAID 10 |
| RAM Slots | 16 | 16 | 16 | 16 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| Rail Kit Included | Yes | Yes | No | No | N/A |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 8 | 8 | 12 | 12 |
| Storage Type | SATA HDD | SATA HDD | SATA HDD | Hybrid | Hybrid |
| Use Case | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server | Virtualization | Virtualization / File Server / Application Server / Data Center | Virtualization |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 45 lbs | 35 lbs | 65 lbs | 45 | 45 lbs |
| Width | 17.2 inches | 17.3 inches | 17.2 inches | 17.3 | 17.3 inches |
Reviews & Ratings
K
Kamran Latif
5
Solid base for custom storage builds.
P
Pavel Novak
5
Good build quality and airflow.
D
Daniel Wright
5
Predictable results after configuration.
A
Adeel Raza
5
Reliable enterprise foundation.
Questions & Answers
What processors are supported by the HPE ProLiant DL385 Gen10 CTO Mod-X 24 SFF Server (SKU: 878613-B21)?
The HPE ProLiant DL385 Gen10 CTO Mod-X 24 SFF Server supports 2nd- and 3rd-generation AMD EPYC™ processors with up to 64 cores per CPU, delivering scalable compute performance for virtualization, database, and HPC workloads.
How much memory can the HPE ProLiant DL385 Gen10 CTO Mod-X hold?
This server accommodates up to 32 DDR4 DIMM slots, supporting a maximum of 4 TB of memory with HPE TruDDR4 modules, enabling high-density in-memory databases and accelerated analytics.
What storage options are available for the HPE ProLiant DL385 Gen10 CTO Mod-X 24 SFF Server?
The system offers 24 small-form-factor (SFF) drive bays compatible with SAS, SATA, and NVMe drives. You can configure up to 184 TB of SAS/SATA storage or 153.6 TB of NVMe storage to meet performance and capacity needs.
Which power supply configurations does this HPE server support?
It supports hot-plug, redundant power supplies in 500 W, 800 W, and 1600 W Flex Slot options with up to 94% efficiency to ensure high availability and reduced energy costs.
Does the HPE ProLiant DL385 Gen10 CTO Mod-X include remote management features?
Yes. It includes HPE Integrated Lights-Out (iLO) 5 with RESTful API, enabling remote server provisioning, monitoring, firmware updates, and enhanced security through iLO Federation and Advanced Premium Security Edition.
How many PCIe expansion slots are available in this server?
The server features eight PCIe Gen4 slots (six full-height, full-length and two half-height, half-length), providing ample connectivity for accelerators, networking cards, and storage controllers.
What network connectivity options come with the DL385 Gen10 CTO Mod-X?
It ships with embedded FlexibleLOM supporting 10/25 GbE or 10/25/100 GbE modules. Additional NICs can be installed in PCIe slots to expand bandwidth or add Fibre Channel connectivity.
Which operating systems are certified for the HPE ProLiant DL385 Gen10?
HPE certifies this server for multiple OS environments, including Windows Server, Red Hat Enterprise Linux, SUSE Linux Enterprise Server, VMware vSphere, and major open-source distributions.
Can I use GPUs with the HPE ProLiant DL385 Gen10 CTO Mod-X 24 SFF Server?
Yes. The chassis supports up to three double-wide GPUs or six single-wide accelerators in available PCIe Gen4 slots, making it ideal for AI/ML, graphics rendering, and compute-intensive tasks.
What security features are included in this ProLiant server?
Security features include HPE Silicon Root of Trust, secure boot, secure firmware rollback, runtime firmware validation, and TPM 2.0 to protect firmware, data, and systems against threats.
Is the DL385 Gen10 CTO Mod-X optimized for virtualization?
Absolutely. With high core counts, large memory capacity, and HPE Distributed Smart Array controllers, it supports dense virtual machine deployment in VMware, Microsoft Hyper-V, and open-source hypervisors.
What does CTO Mod-X mean for this HPE ProLiant server?
CTO Mod-X stands for Configure-to-Order Modular Experience, allowing you to tailor CPU, memory, storage, networking, and power supplies to your specific workload requirements at the time of purchase.
What are the physical dimensions of the HPE ProLiant DL385 Gen10 CTO Mod-X?
This is a 2U rack-mount chassis measuring 86 mm (H) × 447 mm (W) × 739 mm (D) and weighing up to 27 kg fully configured, fitting standard 19-inch server racks.
Does HPE offer warranty and support for the DL385 Gen10 CTO Mod-X?
Yes. It comes with a standard 3-year parts, 3-year labor, and 3-year on-site support warranty, with options to upgrade to HPE Foundation Care or HPE Proactive Care for enhanced SLAs and response times.
How energy efficient is the HPE ProLiant DL385 Gen10 CTO Mod-X Server?
Featuring 94% efficient power supplies, advanced cooling, and HPE Thermal Discovery Services, it minimizes power consumption and optimizes thermal performance for reduced TCO.
What typical workloads is the HPE ProLiant DL385 Gen10 CTO Mod-X best suited for?
This server excels in virtualization, database management, high-performance computing, big data analytics, and cloud environments thanks to its scalable CPU, memory, and storage capabilities.