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8SFF CTO chassis suits performance focused builds.
878612-B21
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HPE ProLiant DL385 Gen10 CTO Mod-X 8 Small Form Factor Serve...
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878612-B21
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- HPE ProLiant DL385 Gen10 CTO Mod-X 8 Small Form Factor Server
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878612-B21 Overview
878612-B21 is a high-performance rackmount server engineered for data center and virtualization environments. It supports Intel Xeon Scalable processors of the Xeon 4th Gen series with a 2P scalability via LGA 4677 sockets, paired with ECC DDR5 memory across 16 slots that can reach up to 2 TB of RAM. The system features 4 PCIe 4.0 expansion slots, along with 8 dedicated 2.5-inch storage bays supporting NVMe SSDs in a RAID 10 configuration for data integrity and performance. Additionally, it provides four 10GbE LAN ports for robust network connectivity.
The server is powered by dual redundant 1000W power supplies with active cooling for optimal thermal management and reliability. Remote management is facilitated via an integrated iDRAC interface, and the system is pre-qualified for operating systems such as VMware ESXi. This design makes 878612-B21 an excellent choice for use cases spanning data centers, virtualization, file serving, and application hosting.
878612-B21 price is is available on request. Get immediate quote.
Request bulk order quote for 878612-B21 for additional pricing. Browse the full Hpe Proliant Dl385 Gen10 Servers series or explore all Hpe products.
878612-B21 Specifications
- Width
- 17.5
- Depth
- 28
- Height
- 3.5
- Form Factor
- Rackmount
- PCIe Version
- PCIe 4.0
- RAID Support
- RAID 10
- Product Type
- Server
- Rack Units
- 2U
- Processor Brand
- Intel
- Processor Series
- Intel Xeon Scalable
- Processor Generation
- Xeon 4th Gen
- CPU Socket
- LGA 4677
- Scalability
- 2P
- Max Cores per CPU
- 32
- Max Threads per CPU
- 64
- RAM Slots
- 16
- Max RAM Capacity
- 2 TB
- Storage Bays
- 8
- Hot-Swap Support
- Yes
- PCIe Slots
- 4
- Network Interface
- 10GbE
- Remote Management
- iDRAC
- Power Supply
- Redundant
- Cooling
- Active
- Virtualization Ready
- Yes
- GPU Support
- Yes
- Drive Bay Size
- 2.5-inch
- Operating System
- VMware ESXi
- Rail Kit Included
- Yes
- Power Supply Wattage
- 1000W
- LAN Ports
- 4
- Storage Type
- NVMe SSD
- Use Case
- Virtualization / File Server / Application Server
- Weight
- 50
- RAM Type
- ECC DDR5
- Product Name
- 878612-B21 Enterprise Server
878612-B21 Use Case
Virtualization Consolidation for SMB IT Infrastructures
In a mid-sized enterprise IT environment, the 878612-B21 HPE ProLiant DL385 Gen10 CTO Mod-X 8 Small Form Factor Server hosts VMware vSphere with eight high-performance AMD EPYC cores and 128 GB DDR4 memory. By consolidating 10+ virtual machines onto a single chassis, IT teams achieve 45% lower rack space usage, streamlined management through HPE iLO, and 30% reduction in power and cooling costs.
High-Performance SQL Database Acceleration
A financial services firm runs mission-critical Microsoft SQL Server workloads on the 878612-B21 HPE ProLiant DL385 Gen10 CTO Mod-X 8 SFF Server, leveraging NVMe drives and AMD EPYC multi-threading. This deployment delivers sub-millisecond query response times for 2 TB transactional databases, ensures 99.99% uptime with HPE SmartArray RAID, and scales I/O performance by 3× to support peak trading hours.
Scalable VDI Deployment for Distributed Offices
A global consultancy rolls out Citrix Virtual Apps & Desktops across 50 branch locations using the 878612-B21 HPE ProLiant DL385 Gen10 CTO Mod-X 8 SFF Server. Each node supports up to 120 concurrent remote desktops with 4 GB RAM per user, delivering accelerated login times under 10 seconds, centralized image management via HPE OneView, and a 25% reduction in endpoint hardware spend.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table 
| 878612-B21 |  878615-B21 |  P00326-S01 |  878619-B21 |  P09708-B21 | |
|---|---|---|---|---|---|
| CPU Socket | LGA 4677 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Cooling | Active | Active | Active | Active | Active |
| Depth | 28 | 27.6 inches | 27 inches | 28 inches | 28 inches |
| Drive Bay Size | 2.5-inch | 3.5-inch | Mixed | 3.5-inch | Mixed |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | Yes | Yes | Yes | Yes | Yes |
| Height | 3.5 | 3.44 inches | 3.5 inches | 3.5 inches | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 4 | 2 | 4 | 4 | 4 |
| Max Cores per CPU | 32 | 32 | 32 | 32 | 32 |
| Max RAM Capacity | 2 TB | 512 GB | 512 GB | 1 TB | 1 TB |
| Max Threads per CPU | 64 | 64 | 64 | 64 | 64 |
| Network Interface | 10GbE | 1GbE | 10GbE | 10GbE | 10GbE |
| Operating System | VMware ESXi | Windows Server / VMware ESXi / Ubuntu / RHEL | Windows Server / VMware ESXi / Ubuntu | Windows Server / VMware ESXi / Ubuntu | VMware ESXi |
| PCIe Slots | 4 | 4 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 1000W | 750W | 750W | 1000W | 1000W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 4th Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | 878612-B21 Enterprise Server | 878615-B21 | P00326-S01 Enterprise Server | 878619-B21 Enterprise Rack Server | P09708-B21 Enterprise Rackmount Server |
| Product Type | Server | Server | Server | Server | Server |
| RAID Support | RAID 10 | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 0 / RAID 1 / RAID 5 | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 10 |
| RAM Slots | 16 | 16 | 8 | 16 | 16 |
| RAM Type | ECC DDR5 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| Rail Kit Included | Yes | Yes | N/A | Yes | Yes |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 8 | 6 | 8 | 8 |
| Storage Type | NVMe SSD | SATA HDD | SATA SSD | SATA HDD | NVMe SSD |
| Use Case | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server | Virtualization |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 50 | 35 lbs | 50 lbs | 50 lbs | 50 lbs |
| Width | 17.5 | 17.3 inches | 19 inches | 17.2 inches | 17.5 inches |
Reviews & Ratings
U
Umer Farooq
5
Reliable base for compute workloads.
K
Klaus Becker
5
Good airflow and serviceability.
J
James Turner
5
Predictable enterprise behavior.
B
Bilal Hussain
5
Stable after deployment.
Questions & Answers
What are the key specifications of the HPE ProLiant DL385 Gen10 CTO Mod-X 8 SFF server (SKU: 878612-B21)?
The HPE ProLiant DL385 Gen10 CTO Mod-X 8 Small Form Factor server (878612-B21) features dual AMD EPYC processor sockets, up to 2 TB DDR4 ECC memory across 16 DIMM slots, eight 2.5″ drive bays, HPE SmartArray storage controllers, flexible LOM networking, and HPE iLO 5 integrated management.
Which processors are supported by the HPE ProLiant DL385 Gen10 CTO Mod-X 8 SFF server?
The server supports the full range of 1st and 2nd Gen AMD EPYC 7002 and 7003 series CPUs, offering up to 64 cores per socket for high-performance compute workloads.
What is the maximum memory capacity of the HPE ProLiant DL385 Gen10 CTO Mod-X 8 SFF server?
This chassis supports up to 2 TB of DDR4 SmartMemory (Registered DIMMs) using sixteen DIMM slots, delivering high memory bandwidth and advanced error correction.
How many storage drive bays does the HPE ProLiant DL385 Gen10 CTO Mod-X 8 SFF server include?
The server provides eight Small Form Factor (2.5″) hot-plug drive bays, enabling flexible configurations of NVMe, SAS, or SATA SSDs and HDDs for balanced performance and capacity.
What storage controllers come standard with the HPE ProLiant DL385 Gen10 CTO Mod-X 8 SFF server?
It ships with an HPE SmartArray S100i Software RAID on the motherboard and offers optional hardware RAID controllers such as the SmartArray P408i-a for RAID 0/1/5/6/10/50/60 support.
What networking connectivity options are available on the HPE ProLiant DL385 Gen10 CTO Mod-X 8 SFF server?
Standard networking includes an integrated FlexibleLOM slot supporting 10/25/40/100 GbE adapters, with additional PCIe slots for extra NICs or converged network adapters.
Can the HPE ProLiant DL385 Gen10 CTO Mod-X 8 SFF server support GPU or accelerator cards?
Yes, the server’s PCIe Gen4 slots accommodate up to two full-height, half-length GPUs or accelerators, enabling AI, ML, and HPC acceleration.
What integrated management features does the HPE ProLiant DL385 Gen10 CTO Mod-X 8 SFF server offer?
The server includes HPE Integrated Lights-Out (iLO) 5 for remote management, HPE OneView for infrastructure automation, and RESTful API support for seamless DevOps integration.
Which operating systems are compatible with the HPE ProLiant DL385 Gen10 CTO Mod-X 8 SFF server?
It is certified for Red Hat Enterprise Linux, SUSE Linux Enterprise Server, VMware vSphere, Microsoft Windows Server, and supports major Linux distributions for maximum flexibility.
What are the power and cooling specifications of the HPE ProLiant DL385 Gen10 CTO Mod-X 8 SFF server?
This model supports up to two hot-plug HPE Flexible Slot Platinum or Titanium power supplies (800 W–1600 W) and features redundant variable-speed fans for efficient thermal management.
What is the form factor and chassis design of the HPE ProLiant DL385 Gen10 CTO Mod-X 8 SFF server?
The server is a 2U rack-mount chassis designed for eight 2.5″ drives, offering high density in a standard datacenter rack footprint.
How does the HPE ProLiant DL385 Gen10 CTO Mod-X 8 SFF server ensure platform security?
It features HPE Silicon Root of Trust, secure boot, runtime firmware verification, and TPM 2.0 support to protect against firmware attacks and unauthorized changes.
What warranty and support options are available for the HPE ProLiant DL385 Gen10 CTO Mod-X 8 SFF server?
It includes a one-year parts, labor, and on-site support warranty, with optional HPE Foundation Care and HPE Proactive Care services for extended coverage and proactive monitoring.
What are the ideal use cases for the HPE ProLiant DL385 Gen10 CTO Mod-X 8 SFF server?
This server excels in virtualization, database management, high-performance computing, software-defined storage, and mixed-workload environments requiring high core density and memory bandwidth.
Can I customize the HPE ProLiant DL385 Gen10 CTO Mod-X 8 SFF server configuration?
Yes, the CTO (Configure-To-Order) model allows you to select CPUs, memory modules, storage controllers, drive types, networking adapters, and power supplies to meet specific workload requirements.
Is the HPE ProLiant DL385 Gen10 CTO Mod-X 8 SFF server energy efficient?
Yes, it leverages HPE Power Discovery Services, high-efficiency power supplies (80 PLUS Platinum/Titanium), and dynamic power capping to optimize energy consumption and reduce operational costs.