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878720-B21
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- HPE ProLiant DL385 Gen10 7401 1P 32GB-R P408i-a 24SFF SAS 800W PS Base Server
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878720-B21
HPE ProLiant DL385 Gen10 7401 1P 32GB-R P408i-a 24...
$7,482.47
15 in Global Warehouse
$7,482.47
7% off
TRUSTED, TRIED, PROVEN
878720-B21 Overview
878720-B21 is a robust rackmount server built to deliver high performance in demanding data center and enterprise environments. It supports Intel Xeon Scalable processors with an LGA 4189 socket in a 2P configuration, paired with ECC DDR4 memory capacity of up to 1 TB across 16 slots, and features 4 PCIe 4.0 expansion slots alongside comprehensive dual 10GbE network interfaces, making it ideal for virtualization, file serving, and application hosting.
This enterprise server is engineered for reliability with redundant 800W power supplies, active cooling, and integrated remote management via iDRAC, ensuring continuous operation in critical environments. It also offers versatile storage options with 8 hot-swap 3.5-inch drive bays supporting RAID 5 configurations, rendering it perfectly suited for data center deployments and mission-critical application infrastructures.
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878720-B21 Specifications
| Product Type | Server |
| Form Factor | Rackmount |
| Rack Units | 2U |
| Processor Brand | Intel |
| Processor Series | Intel Xeon Scalable |
| Processor Generation | Xeon 3rd Gen |
| Use Case | Data Center / Virtualization / File Server / Application Server |
| CPU Socket | LGA 4189 |
| Scalability | 2P |
| Max Cores Per CPU | 32 |
| Max Threads Per CPU | 64 |
| RAM Type | ECC DDR4 |
| RAM Slots | 16 |
| Max RAM Capacity | 1 TB |
| Storage Type | SATA HDD |
| Storage Bays | 8 |
| Drive Bay Size | 3.5-inch |
| Hot-Swap Support | Yes |
| RAID Support | RAID 5 |
| PCIe Slots | 4 |
| PCIe Version | PCIe 4.0 |
| Network Interface | 10GbE |
| LAN Ports | 2 |
| Remote Management | iDRAC |
| Power Supply | Redundant |
| Power Supply Wattage | 800W |
| Cooling | Active |
| Operating System | Windows Server |
| Virtualization Ready | Yes |
| GPU Support | Yes |
| Rail Kit Included | Yes |
| Product Name | 878720-B21 Enterprise Rackmount Server |
| Height | 3.44 |
| Width | 17.32 |
| Depth | 29.53 |
| Weight | 38 lbs |
878720-B21 Use Case
Virtualization Consolidation with HPE ProLiant DL385 Gen10
A mid-sized enterprise deploys the 878720-B21-HPE ProLiant DL385 Gen10 7401 1P 32GB-R P408i-a 24SFF SAS 800W PS Base Server as a VMware ESXi host to consolidate 50+ virtual machines onto a single platform. Leveraging the AMD EPYC 7401 processor and 24 SFF SAS bays improves CPU density, accelerates I/O throughput, and reduces rack space. Outcome: 40% lower hardware costs, 30% faster VM provisioning, and simplified capacity planning for growth.
High-Performance Transactional Database Workloads
A financial services firm implements the 878720-B21-HPE ProLiant DL385 Gen10 to power a Microsoft SQL Server environment handling real-time trading transactions. The P408i-a RAID controller and multi-lane SAS connectivity deliver sustained 200,000 IOPS and sub-millisecond latency for critical OLTP workloads. Benefit: guaranteed transaction throughput, 99.99% system availability, and streamlined compliance reporting.
Hyper-Converged Infrastructure for Remote Offices
A global retailer deploys three 878720-B21-HPE ProLiant DL385 Gen10 nodes running Nutanix AOS at its regional distribution centers. Each node’s 32 GB memory, AMD EPYC cores, and redundant 800 W power supplies enable inline deduplication, compression, and automated failover. Result: consolidated compute/storage footprint, 50% faster site roll-outs, and centralized management with zero-touch updates.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table
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| Cooling | Active | Active | Active | Active | Active |
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Depth | 29.53 | 28.0 inches | 28 | 28 inches | 27.5 inches |
| Drive Bay Size | 3.5-inch | 2.5-inch | 2.5-inch | 3.5-inch | 3.5-inch |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | Yes | No | Yes | No | Yes |
| Height | 3.44 | 3.5 inches | 3.5 | 3.5 inches | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 2 | 4 | 4 | 2 | 4 |
| Max Cores per CPU | 32 | 32 | 32 | 32 | 32 |
| Max RAM Capacity | 1 TB | 512 GB | 1 TB | 1 TB | 512 GB |
| Max Threads per CPU | 64 | 64 | 64 | 64 | 64 |
| Network Interface | 10GbE | 1GbE | 10GbE | 1GbE | 10GbE |
| Operating System | Windows Server | Windows Server | VMware ESXi | Windows Server | Windows Server / VMware ESXi / Ubuntu |
| PCIe Slots | 4 | 4 | 4 | 6 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 800W | 750W | 1200W | 750W | 750W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 4th Gen | Xeon 3rd Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | 878720-B21 Enterprise Rackmount Server | P00323-S01 High Performance Rackmount Server | 878614-B21 High Performance Rack Server | 878617-B21 | P00324-S01 |
| Product Type | Server | Server | Server | Server | Server |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| RAID Support | RAID 5 | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 10 | RAID 0/RAID 1/RAID 5/RAID 10 | RAID 10 |
| Rail Kit Included | Yes | Yes | N/A | N/A | No |
| RAM Slots | 16 | 16 | 16 | 16 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 8 | 8 | 4 | 8 |
| Storage Type | SATA HDD | SATA SSD | NVMe SSD | SATA SSD | SATA HDD |
| Use Case | Data Center / Virtualization / File Server / Application Server | Virtualization | Virtualization / File Server / Application Server | Virtualization | Virtualization / File Server / Application Server |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 38 lbs | 45 lbs | 45 | 45 lbs | 65 lbs |
| Width | 17.32 | 17.0 inches | 17 | 17.5 inches | 17.3 inches |
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Questions & Answers
Q
What are the key specifications of the HPE ProLiant DL385 Gen10 7401 1P 32GB-R P408i-a 24SFF SAS 800W PS Base Server?
A
The DL385 Gen10 features a single AMD EPYC 7401P 16-core processor, 32 GB DDR4-2666 RDIMM, HPE Smart Array P408i-a RAID controller, 24 SFF drive bays, 800 W hot-plug power supply and integrated HPE iLO 5 management.
Q
Which CPU does the HPE ProLiant DL385 Gen10 7401 1P use?
A
It uses the AMD EPYC 7401P single-socket processor offering 16 cores, 32 threads and a base clock of 2.0 GHz, burst up to 3.0 GHz.
Q
How much memory comes installed and what is the maximum supported?
A
The server ships with 32 GB of DDR4-2666 RDIMM across four DIMM slots and supports up to 2 TB using sixteen DIMM modules.
Q
What storage capacity and drive types are supported?
A
It supports up to 24 SFF SAS or SATA drives (2.5-inch) with a total raw capacity scalable to multiple petabytes, depending on drive selection.
Q
Which RAID levels does the HPE Smart Array P408i-a controller support?
A
The P408i-a supports RAID 0, 1, 5, 6, 10, 50 and 60 with cache protection and up to 24 internal drive endpoints.
Q
What type of power supply is included and is it redundant?
A
An 800 W hot-plug, high-efficiency (94%+) power supply is included; this base configuration does not include redundant PSUs but can be upgraded to N+1 redundancy.
Q
How do I manage and monitor the server remotely?
A
Integrated HPE iLO 5 provides secure remote management, monitoring, firmware updates and out-of-band control via web console or RESTful APIs.
Q
How many PCIe expansion slots are available?
A
The chassis provides three full-height, full-length PCIe Gen4 slots for network, storage or accelerator cards.
Q
Which operating systems are supported?
A
Supported OSes include VMware ESXi, Microsoft Windows Server, Red Hat Enterprise Linux, SUSE Linux Enterprise Server and Ubuntu LTS.
Q
Is the DL385 Gen10 suitable for virtualization workloads?
A
Yes, with up to 16 cores, large memory capacity and high I/O throughput, it’s optimized for VMware, Hyper-V and containerized environments.
Q
What are the server’s dimensions and weight?
A
It measures 2U high, 86 mm (H) x 438 mm (W) x 714 mm (D) and weighs approximately 19 kg fully configured.
Q
What warranty does this server include?
A
Standard HPE limited warranty of 3 years parts, labor and on-site support with next business day response.
Q
Does the DL385 Gen10 support NVMe drives?
A
With optional NVMe backplane kits and compatible NVMe SSDs, it supports up to 24 NVMe drives for ultra-low latency storage.
Q
What energy-efficiency features does it offer?
A
Features include HPE Power Discovery Services, dynamic power capping, efficient 94%+ power supplies and BIOS power-optimization settings.
Q
What networking options are available out of the box?
A
Integrated FlexibleLOM supports up to four 10/25 GbE ports; additional network adapters can be installed in PCIe slots.
Q
How can I expand the memory in this server?
A
Add up to 12 additional DDR4 RDIMM modules in available DIMM slots, mixing only identical size and speed modules to meet capacity requirements.