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8LFF CTO provides flexible SATA configurations.
878615-B21
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HPE ProLiant DL385 Gen10 CTO Mod-X 8 Large Form Factor Serve...
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878615-B21
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- HPE ProLiant DL385 Gen10 CTO Mod-X 8 Large Form Factor Server
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878615-B21 Overview
878615-B21 is a high-performance rackmount server built on Intel Xeon Scalable 3rd Gen processors featuring the LGA 4189 socket. It supports dual-processor (2P) configurations with up to 32 cores and 64 threads per CPU, paired with ECC DDR4 memory across 16 slots that can be expanded to a maximum of 512 GB, and offers 4 PCIe 4.0 expansion slots.
Engineered for demanding data center environments, 878615-B21 includes 8 hot-swap bays for 3.5-inch SATA HDDs with RAID 0, RAID 1, RAID 5, and RAID 10 support, along with dual 1GbE network interfaces. The server delivers reliable performance through its redundant 750W power supplies, active cooling system, and iDRAC remote management, making it an ideal choice for virtualization, file server, and application server use cases under operating systems such as Windows Server, VMware ESXi, Ubuntu, and RHEL.
878615-B21 price is is available on request. Get immediate quote.
Request bulk order quote for 878615-B21 for additional pricing. Browse the full Hpe Proliant Dl385 Gen10 Servers series or explore all Hpe products.
878615-B21 Specifications
- Width
- 17.3 inches
- Weight
- 35 lbs
- Height
- 3.44 inches
- Form Factor
- Rackmount
- RAID Support
- RAID 0 / RAID 1 / RAID 5 / RAID 10
- PCIe Version
- PCIe 4.0
- CPU Socket
- LGA 4189
- Product Type
- Server
- Rack Units
- 2U
- Processor Brand
- Intel
- Processor Series
- Intel Xeon Scalable
- Scalability
- 2P
- Max Cores per CPU
- 32
- Max Threads per CPU
- 64
- RAM Type
- ECC DDR4
- RAM Slots
- 16
- Storage Type
- SATA HDD
- Storage Bays
- 8
- Hot-Swap Support
- Yes
- PCIe Slots
- 4
- LAN Ports
- 2
- Remote Management
- iDRAC
- Power Supply
- Redundant
- Cooling
- Active
- Virtualization Ready
- Yes
- GPU Support
- Yes
- Processor Generation
- Xeon 3rd Gen
- Max RAM Capacity
- 512 GB
- Rail Kit Included
- Yes
- Drive Bay Size
- 3.5-inch
- Network Interface
- 1GbE
- Power Supply Wattage
- 750W
- Use Case
- Virtualization / File Server / Application Server
- Operating System
- Windows Server / VMware ESXi / Ubuntu / RHEL
- Depth
- 27.6 inches
- Product Name
- 878615-B21
878615-B21 Use Case
Private Cloud Virtualization and Consolidation
Deploy the 878615-B21-HPE ProLiant DL385 Gen10 CTO Mod-X 8 LFF Server as a VMware vSphere or Microsoft Hyper-V host to consolidate 50+ virtual machines. Benefit: Delivers up to 2× compute efficiency and 30% lower TCO through high-density AMD EPYC™ cores and flexible storage expansion, enabling agile private cloud operations at enterprise scale.
High-Performance Database and Analytics Acceleration
Run mission-critical Oracle, SAP HANA, or Microsoft SQL Server workloads on the 878615-B21-HPE ProLiant DL385 Gen10 CTO Mod-X 8 LFF Server with NVMe caching. Benefit: Achieves sub-millisecond query response and 4× faster analytics insights by leveraging 3rd Gen AMD EPYC™ processors and HPE Persistent Memory, optimizing real-time decision-making.
AI/ML Model Training and Inference
Utilize the 878615-B21-HPE ProLiant DL385 Gen10 CTO Mod-X 8 LFF Server for TensorFlow and PyTorch workloads in Kubernetes or bare-metal environments. Benefit: Speeds up deep learning training by up to 50% with high-core count CPUs and GPU accelerator support, driving rapid AI innovation and scalable inference pipelines.
Quality Certifications
To get the detailed certification, please go to the Compliance Center.
Product Comparison Table 
| 878615-B21 |  P09707-B21 |  878613-B21 |  878716-B21 |  878619-B21 | |
|---|---|---|---|---|---|
| CPU Socket | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 | LGA 4189 |
| Cooling | Active | Active | Active | Active | Active |
| Depth | 27.6 inches | 28 inches | 28 inches | 28 inches | 28 inches |
| Drive Bay Size | 3.5-inch | 3.5-inch | 3.5-inch | 3.5-inch | 3.5-inch |
| Form Factor | Rackmount | Rackmount | Rackmount | Rackmount | Rackmount |
| GPU Support | Yes | No | No | Yes | Yes |
| Height | 3.44 inches | 3.5 inches | 3.5 inches | 3.5 inches | 3.5 inches |
| Hot-Swap Support | Yes | Yes | Yes | Yes | Yes |
| LAN Ports | 2 | 2 | 4 | 4 | 4 |
| Max Cores per CPU | 32 | 64 | 32 | 32 | 32 |
| Max RAM Capacity | 512 GB | 2 TB | 1 TB | 1 TB | 1 TB |
| Max Threads per CPU | 64 | 128 | 64 | 64 | 64 |
| Network Interface | 1GbE | 10GbE | 10GbE | 1GbE | 10GbE |
| Operating System | Windows Server / VMware ESXi / Ubuntu / RHEL | Windows Server / VMware ESXi / Ubuntu / RHEL | Windows Server | Windows Server | Windows Server / VMware ESXi / Ubuntu |
| PCIe Slots | 4 | 4 | 4 | 4 | 4 |
| PCIe Version | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 | PCIe 4.0 |
| Power Supply | Redundant | Redundant | Redundant | Redundant | Redundant |
| Power Supply Wattage | 750W | 1600W | 800W | 1000W | 1000W |
| Processor Brand | Intel | Intel | Intel | Intel | Intel |
| Processor Generation | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen | Xeon 3rd Gen |
| Processor Series | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable | Intel Xeon Scalable |
| Product Name | 878615-B21 | P09707-B21 Enterprise Server | 878613-B21 | 878716-B21 | 878619-B21 Enterprise Rack Server |
| Product Type | Server | Server | Server | Server | Server |
| RAID Support | RAID 0 / RAID 1 / RAID 5 / RAID 10 | RAID 0 / RAID 1 / RAID 5 / RAID 6 / RAID 10 | RAID 5 | RAID 5 | RAID 0 / RAID 1 / RAID 5 / RAID 10 |
| RAM Slots | 16 | 16 | 16 | 16 | 16 |
| RAM Type | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 | ECC DDR4 |
| Rack Units | 2U | 2U | 2U | 2U | 2U |
| Rail Kit Included | Yes | N/A | Yes | No | Yes |
| Remote Management | iDRAC | iDRAC | iDRAC | iDRAC | iDRAC |
| Scalability | 2P | 2P | 2P | 2P | 2P |
| Storage Bays | 8 | 8 | 8 | 8 | 8 |
| Storage Type | SATA HDD | SATA HDD | SATA HDD | SATA HDD | SATA HDD |
| Use Case | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server | Virtualization / File Server / Application Server | Virtualization | Virtualization / File Server / Application Server |
| Virtualization Ready | Yes | Yes | Yes | Yes | Yes |
| Weight | 35 lbs | 60 lbs | 45 lbs | 65 lbs | 50 lbs |
| Width | 17.3 inches | 17 inches | 17.2 inches | 17.2 inches | 17.2 inches |
Reviews & Ratings
A
Adnan Qadir
4
Good option for capacity driven roles.
O
Olivier Martin
5
Consistent cooling and performance.
P
Paul Ridley
4
Easy rack integration.
S
Sami Ullah
5
Meets storage requirements well.
Questions & Answers
What are the key specifications of the HPE ProLiant DL385 Gen10 CTO Mod-X 8 LFF Server (SKU: 878615-B21)?
The HPE ProLiant DL385 Gen10 CTO Mod-X 8 LFF features dual AMD EPYC™ processors, up to 4.5TB DDR4 memory, eight 3.5″ drive bays, HPE iLO for management, redundant Platinum power supplies, and HPE Smart Array controllers.
Which processor options are supported by this server?
This server supports dual AMD EPYC 7002 and 7003 series CPUs, offering up to 64 cores per processor for high-performance compute and virtualization workloads.
How much memory can the DL385 Gen10 CTO Mod-X accommodate?
It supports up to 32 DDR4 DIMM slots with a maximum capacity of 4.5TB using 128GB RDIMMs or LRDIMMs, enabling large-scale in-memory and virtualization applications.
What storage configurations are available in the 8 LFF chassis?
The server offers eight hot-plug 3.5″ drive bays supporting SAS, SATA, and NVMe SSDs or HDDs, delivering up to 112TB raw capacity and high-I/O options with NVMe modules.
Which RAID controllers are compatible with this HPE server?
Compatible controllers include the HPE Smart Array P408i-a, P816i-a, and HPE Smart HBA, providing hardware RAID levels 0/1/5/6/10/50/60 for data protection and performance.
What networking options does the DL385 Gen10 support?
Standard FlexibleLOM options include 1/10/25/40/100Gb Ethernet adapters. Additional PCIe slots support 1/10/25/40/50/100Gb NICs for high-speed networking and RDMA.
Can I add GPUs for AI and ML workloads?
Yes. The CTO Mod-X chassis supports up to three single-width or two dual-width GPUs (NVIDIA Tesla or AMD Instinct) in available PCIe Gen4 slots for AI/ML acceleration.
Which hypervisors and operating systems are supported?
Certified for VMware vSphere, Microsoft Hyper-V, Red Hat Enterprise Linux, SUSE Linux Enterprise Server, Ubuntu, CentOS, and other major Linux distributions and bare-metal deployments.
What remote management features are included?
HPE iLO 5 provides out-of-band management with automated provisioning, health monitoring, firmware updates, scripting, and remote KVM, reducing downtime and administrative effort.
How energy efficient is the DL385 Gen10?
Equipped with redundant HPE Platinum or Titanium power supplies and Smart Power Capping, the server meets 80 PLUS Platinum/Titanium standards for efficient power delivery and cooling.
What security features are integrated into this server?
Security includes HPE Silicon Root of Trust, Secure Boot, Runtime Firmware Validation, TPM 2.0, and drive encryption options to protect critical firmware, data, and credentials.
How scalable is the HPE ProLiant DL385 Gen10 CTO Mod-X?
The platform scales from entry-level to enterprise: add CPUs, expand memory to 4.5TB, increase storage up to 112TB, and attach multiple networking or GPU cards for growth.
What are the typical use cases for this server?
Ideal for virtualization, database analytics, HPC, cloud deployments, AI/ML inference, enterprise applications, and software-defined storage requiring high CPU, memory, and I/O density.
How does the DL385 Gen10 compare to the DL380 Gen10?
The DL385 uses AMD EPYC for higher core counts and memory capacity, while the DL380 uses Intel Xeon. The DL385 offers superior price/performance for multi-threaded workloads.
What warranty and support options are available?
Standard HPE 3-year parts, labor, and onsite support. Optional HPE Foundation Care, Proactive Care, and Datacenter Care services for 24×7 critical support and rapid hardware replacement.
What PCIe expansion options are provided?
Up to 8 PCIe Gen4 slots (mix of x16 and x8) allow installation of additional NICs, HBAs, GPUs, NVMe adapters, and accelerators for flexible workload acceleration and connectivity.